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Adoption & Foster Care Certificate Program

THE CERTIFICATE IN ADOPTION AND FOSTER CARE PRACTICE provides clinical and practical training for those working with families and children whose lives are touched by the issues of foster care and adoption.

Please note: Workshops in the Adoption and Foster Care Practice Certificate Program are open to all. You do not need to be seeking an AFCC certificate.

Our Vision: Adoption and foster care competent professionals throughout the greater Rhode Island area.

Our Mission: Through the Adoption and Foster Care Certificate program, we will promote adoption and foster care competent professionals as resources to support permanency for children in Rhode Island’s child welfare system.

Pre-2014 Certificate Completion Form - This form applies to participants who started the program prior to the Fall semester of 2014.

Current Certificate Completion Form - This form applies to participants who started the program during or after the Fall semester of 2014.

Program Requirements:

There are eleven required core courses. Participants will also be required to attend three elective courses, which cover a wide range of topics. In order to receive credit towards the certificate, participants are asked to complete a short post-test. Courses are held at the Rhode Island College School of Social Work. Core courses are listed below. Please click on each course title for further information.

Core Workshops :

AFCC-36 Policy and Advocacy: Impacts on Care and Adoption (Core)

AFCC-37 Understanding Core Clinical Issues in Foster Care and Adoption (Core)

AFCC-38 Trauma & Brain Development: Foundations for Foster Care & Adoption Practice (Core)

AFCC-47 Ethics: Reflective Practice (Core)

There are no elective workshops for the AFCC program this semester.

Course Descriptions:

AFCC-36 Policy and Advocacy: Impacts on Care and Adoption (Core)

This course focuses on the history of child welfare in Rhode Island. Relevant laws and policies are discussed and dissected to determine their impacts on adoption and foster care. Participants learn about the importance of advocacy and use role-playing to demonstrate new skills and knowledge.

AFCC-37 Understanding Core Clinical Issues in Foster Care and Adoption (Core)

This workshop explores seven core clinical issues associated with adoption & foster care practice. Through the training, participants cultivate an understanding of these clinical issues and their relevance to the human experience and the meaning they hold for individuals. The workshop presents a strength-based approach to viewing developmental and situational aspects of adoption & foster care experiences. Scenario-based exercises are used to allow participants to make connections with the new knowledge learned.

AFCC-38 Trauma & Brain Development: Foundations for Foster Care & Adoption Practice (Core)

This training explores neurological and environmental effects of trauma on children who are survivors of abuse and neglect. During training, participants learn about brain development in children and adolescents. This course also introduces participants to strategies that assist with healing from trauma and techniques for creating healthy relationships.

AFCC-47 Ethics: Reflective Practice

This workshop addresses the identification and exploration of ethical and legal issues that are relevant to adoption and foster care. This training provides participants with the opportunity to confront biases that can impact clinical practice. The training provides participants with a framework for ethical decision making.

AFCC Faculty:

AFCC faculty includes professionals from various fields of expertise, such as social work, counseling, and psychology.

Catherine Lewis . MSW & LICSW is a clinical social worker having worked more than 25 years with foster and adoptive children and families. She is an adjunct professor in the Rhode Island College of Social Work and is in private practice. Catherine Lewis is the trainer for AFCC-42 Working With and Understanding the Role of Birth families.

Daniel Harvey . LICSW is an Assistant Professor at the Rhode Island College of School of Social Work. He is a licensed clinician, with approximately three decades of experience in addressing the needs of children experiencing trauma. Daniel Harvey is the trainer for AFCC-38 Foundations for Foster Care and Adoptions Practice: Trauma and Brain Development and AFCC-46 Clinical Work with Foster Care and Adoptive Families: Promoting Positive Identify and Managing Challenging Behaviors.

Deoshore Haig . MSW is the Director of Haig & Associates, has over twenty-five years of experience working with culturally diverse communities in social services, and managing health and human service programs. As an independent consultant, Deoshore’s services include designing and facilitating diversity and cultural competency training, advising in program development, conducting program evaluations, and providing technical assistance for organizational development. Deoshore Haig is the trainer for AFCC-41 Considering the Value and Role of Culture and Diversity.

Frederic Reamer . Ph. D. is professor in the School of Social Work, Rhode Island College. He has published extensively on professional ethics and chaired the national task force that wrote the current NASW Code of Ethics. Reamer frequently serves as an expert witness in litigation and licensing board cases. Frederic Reamer is the trainer for AFCC-47 Ethics: A Reflective Practice.

Lori Geiselman . MSW is a clinical training specialist for the Department of Children, Youth and Families. She has worked primarily within the field of Public Child Welfare. She has held positions as a Social Case Worker II, Clinical Social Worker, and Clinical Training Specialist within the Department of Children, Youth and Families and the Child Welfare Institute. In the last year, Lori is also a clinician for Rhode Island Hospital’s Emergency Services. Lori Geiselman is the trainer for AFCC-37 Understanding Core Clinical Issues in Foster Care and Adoption.

Melinda Gushwa . MSW, PhD, is an assistant professor at Simmons College School of Social Work. She has over 17 years of practice experience in the areas of public child welfare, psychotherapy, mental health case management and medical social work. Melinda Gushwa is the trainer for AFCC-40 Grief and Loss in Foster Care and Adoption.

Pamela Lowell . LICSW is an author and licensed clinical social worker in private practice with twenty-five plus years of experience counseling children and their families. She is a clinical consultant at Adoption Rhode Island where she provides case consultation to staff and community collaborators. Pamela Lowell is the trainer for AFCC-Clinical Work with Foster Care and Adoptive Families: Family Formation and Development Stages.

Contact AFCC

Joining the email list is the most effective way to keep informed on upcoming workshop and course offerings. If you need further assistance, please contact Krista Handfield by phone or email. Email and phone messages are returned with-in 3-5 business days. If you need immediate assistance, please contact the program administrator Sue Pearlmutter. Contact information is below:

Sue Pearlmutter, PhD AFCC Program Administration Dean and Professor Rhode Island College School of Social Work 600 Mount Pleasant Avenue Providence, RI 02908 Email: rpearlmutter@ric. edu Telephone: (401) 456-8043

Krista Handfield Program Coordinator & Graduate Assistant Rhode Island College School of Social Work 600 Mount Pleasant Avenue Providence, RI 02908 Email: afcc@ric. edu Telephone: (401) 456-2753

The Adoption & Foster Care Certificate is a program in partnership with:

Rhode Island College School of Social Work

Rhode Island Department of Children, Youth and Families (DCYF)

Adoption Rhode Island

Beacon Health Strategies

Child & Family

Family Service of Rhode Island



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Acitretin or isotretinoin because side effects, such as increased pressure in the fluid surrounding the brain, may occur

Digoxin, methotrexate, methoxyflurane, or oral anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Sumycin

Atovaquone, lithium, oral contraceptives (birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Sumycin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sumycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Sumycin may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Sumycin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Be sure to use Sumycin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Sumycin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Sumycin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Do not use after expiration date. Outdated medicine is highly toxic to the kidneys.

Long-term or repeated use of Sumycin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Sumycin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Lab tests may be performed while you use Sumycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use of Sumycin in children may cause permanent discoloring of the teeth.

Sumycin should be used with extreme caution in children younger 8 years; safety and effectiveness in these children have not been confirmed.

Pregnancy and beast-feeding: Sumycin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sumycin while you are pregnant. Sumycin is found in breast milk. Do not breast-feed while taking Sumycin.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Black hairy tongue; blurred vision; bulky loose stools; diarrhea; difficulty swallowing; fever; headache; hives; hoarseness; indigestion; inflammation or redness of tongue; joint pain; loss of appetite; mouth sores; nausea; rash; sensitivity to sunlight; sore throat; stomach pain; swelling and itching of the rectum.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); infection (fever, chills, sore throat); itching; nausea; severe skin reaction to the sun; vaginal irritation or discharge; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Sumycin is used for treating infections caused by certain bacteria. Sumycin is a tetracycline antibiotic. It works by slowing the growth of sensitive bacteria by interfering with the production of proteins needed by the bacteria to grow. Slowing the bacteria's growth allows the body's defense mechanisms to destroy them.

Use Sumycin as directed by your doctor.

Take Sumycin by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Take Sumycin with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Sumycin.

If you also take antacids containing aluminum, calcium, or magnesium; preparations containing bismuth, iron, zinc, or sodium bicarbonate; or calcium rich foods (eg, milk, dairy products, calcium-enriched juices), do not take them within 2 to 3 hours before or after taking Sumycin. Check with your doctor if you have questions.

To clear up your infection completely, take Sumycin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Sumycin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sumycin.

Store Sumycin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed, light-resistant container. Keep away from heat, moisture, and light. Do not store in the bathroom. Keep Sumycin out of the reach of children and away from pets.

Active Ingredient: Tetracycline hydrochloride.

Do NOT use Sumycin if:

you are allergic to any ingredient in Sumycin or other tetracycline antibiotics (eg, doxycycline)

you are taking acitretin or methoxyflurane.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Sumycin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have diarrhea, a stomach infection, or kidney problems.

Some medicines may interact with Sumycin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Acitretin or isotretinoin because side effects, such as increased pressure in the fluid surrounding the brain, may occur

Digoxin, methotrexate, methoxyflurane, or oral anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Sumycin

Atovaquone, lithium, oral contraceptives (birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Sumycin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sumycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Sumycin may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Sumycin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Be sure to use Sumycin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Sumycin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Sumycin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Do not use after expiration date. Outdated medicine is highly toxic to the kidneys.

Long-term or repeated use of Sumycin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Sumycin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Lab tests may be performed while you use Sumycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use of Sumycin in children may cause permanent discoloring of the teeth.

Sumycin should be used with extreme caution in children younger 8 years; safety and effectiveness in these children have not been confirmed.

Pregnancy and beast-feeding: Sumycin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sumycin while you are pregnant. Sumycin is found in breast milk. Do not breast-feed while taking Sumycin.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Black hairy tongue; blurred vision; bulky loose stools; diarrhea; difficulty swallowing; fever; headache; hives; hoarseness; indigestion; inflammation or redness of tongue; joint pain; loss of appetite; mouth sores; nausea; rash; sensitivity to sunlight; sore throat; stomach pain; swelling and itching of the rectum.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); infection (fever, chills, sore throat); itching; nausea; severe skin reaction to the sun; vaginal irritation or discharge; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Sumycin is used for treating infections caused by certain bacteria. Sumycin is a tetracycline antibiotic. It works by slowing the growth of sensitive bacteria by interfering with the production of proteins needed by the bacteria to grow. Slowing the bacteria's growth allows the body's defense mechanisms to destroy them.

Use Sumycin as directed by your doctor.

Take Sumycin by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Take Sumycin with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Sumycin.

If you also take antacids containing aluminum, calcium, or magnesium; preparations containing bismuth, iron, zinc, or sodium bicarbonate; or calcium rich foods (eg, milk, dairy products, calcium-enriched juices), do not take them within 2 to 3 hours before or after taking Sumycin. Check with your doctor if you have questions.

To clear up your infection completely, take Sumycin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Sumycin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sumycin.

Store Sumycin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed, light-resistant container. Keep away from heat, moisture, and light. Do not store in the bathroom. Keep Sumycin out of the reach of children and away from pets.

Active Ingredient: Tetracycline hydrochloride.

Do NOT use Sumycin if:

you are allergic to any ingredient in Sumycin or other tetracycline antibiotics (eg, doxycycline)

you are taking acitretin or methoxyflurane.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Sumycin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have diarrhea, a stomach infection, or kidney problems.

Some medicines may interact with Sumycin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Acitretin or isotretinoin because side effects, such as increased pressure in the fluid surrounding the brain, may occur

Digoxin, methotrexate, methoxyflurane, or oral anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Sumycin

Atovaquone, lithium, oral contraceptives (birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Sumycin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sumycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Sumycin may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Sumycin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Be sure to use Sumycin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Sumycin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Sumycin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Do not use after expiration date. Outdated medicine is highly toxic to the kidneys.

Long-term or repeated use of Sumycin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Sumycin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Lab tests may be performed while you use Sumycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use of Sumycin in children may cause permanent discoloring of the teeth.

Sumycin should be used with extreme caution in children younger 8 years; safety and effectiveness in these children have not been confirmed.

Pregnancy and beast-feeding: Sumycin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sumycin while you are pregnant. Sumycin is found in breast milk. Do not breast-feed while taking Sumycin.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Black hairy tongue; blurred vision; bulky loose stools; diarrhea; difficulty swallowing; fever; headache; hives; hoarseness; indigestion; inflammation or redness of tongue; joint pain; loss of appetite; mouth sores; nausea; rash; sensitivity to sunlight; sore throat; stomach pain; swelling and itching of the rectum.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); infection (fever, chills, sore throat); itching; nausea; severe skin reaction to the sun; vaginal irritation or discharge; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.



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Cefixime is used to treat many different types of infections caused by bacteria. Cefixime may also be used for other purposes not listed in this medication guide.

Use Cefixime as directed by your doctor.

Take this medicine with a full glass of water. Cefixime works best if you take it with a meal or within 30 minutes of a meal. Swallow the pill whole. Breaking the pill may cause too much of the drug to be released at one time. Ask your health care provider any questions you may have about how to use Cefixime.

Drug Class and Mechanism

Cefixime is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.

If you miss a dose of Cefixime, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Store Cefixime at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Cefixime out of the reach of children and away from pets. Warnings/Precautions

Do not use Cefixime if:

you are allergic to any ingredient in Cefixime or to other cephalosporins (e. g. cephalexin); you will be having a live typhoid vaccine. Contact your doctor or health care provider right away if any of these apply to you.

Important : Cefixime may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Cefixime with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Cefixime only works against bacteria; it does not treat viral infections (eg, the common cold). Be sure to use Cefixime for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of Cefixime may cause a second infection. Tell your doctor if signs of a second infection occur. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor. Cefixime may reduce the ability of your blood to clot. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bleeding or bruising or dark, tarry, or bloody stools. Diabetes patients - Cefixime may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine. Cefixime may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Cefixime. Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cefixime while you are pregnant. It is not known if Cefixime is found in breast milk. If you are or will be breast-feeding while you use Cefixime, check with your doctor or pharmacist. Discuss any possible risks to your baby.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

diarrhea; gas; loose stools; nausea; stomach pain or upset. Seek medical attention right away if any of these severe side effects occur:

severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; decreased urination; fever; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe nausea or vomiting; severe stomach pain or cramping; unusual bruising or bleeding; vaginal discharge or itching; white spots in the mouth; yellowing of the skin or eyes. More Information

Cefixime is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor.



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Adrexan is a non selective beta blocker which is used in the treatment of hypertension. It may be used alone or with a diuretic to adequately treat hypertension or high blood pressure. Adrexan can also treat other circulatory diseases such as atrial fibrillation, angina pectoris and acute myocardial infarction or heart attack. It is also used in the treatment of migraine headaches, essential tremors, hyperoptic sub aortic stenosis, and phenocromocytoma.

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Actinerval (Tegretol) Description

Actinerval target is the treatment of simple and complex forms of seizure. It is also used to treat nerve pain of the face such as trigeminal neuralgia and diabetic neuropathy, bipolar disorder. Actinerval is acting by reducing the action of nerve which causes pain and seizures. It is anticonvulsant.

Generic name of Actinerval is Carbamazepine.

Actinerval is also known as Carbamazepine, Tegrital.

Brand names of Actinerval are Actinerval, Actinerval XR, Epitol, Equetro, Carbatrol.

Actinerval (Tegretol) Dosage

Actinerval is available in:

100mg Low Dosage

200mg Standard Dosage

400mg Increased Dosage

Actinerval is available in tablets (100 mg, 200 mg, 400 mg), chewable tablets, extended release tablets and suspension.

Do not crush, chew, or break the extended release tablets.

Before taking the liquid form of Actinerval you should shake it.

Chewable tablets should be chewed before swallowing.

The treatment with Actinerval can be resulting after 4 weeks.

For trigeminal neuralgia treatment

The starting dose of Actinerval is 100 mg taken twice a day.

For bipolar disorders treatment

The starting dose of Actinerval is 200-400 mg a day in divided doses.

Take Actinerval at the same time every day, with or without food.

Take Actinerval tablets orally with water.

Avoid grapefruit and grapefruit juice.

If you want to achieve most effective results do not stop taking Actinerval suddenly.

Actinerval (Tegretol) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Actinerval (Tegretol) Overdose

If you overdose Actinerval and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Actinerval overdosage: fast heartbeat, difficulties with shallow and breathing, nausea, impatience, muscle twitches, seizures, dizziness, slurred speech, tremors, languor, vomiting, problems with urinating.

Actinerval (Tegretol) Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Protect from moisture. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Actinerval (Tegretol) Side effects

Actinerval has its side effects. The most common are:

dizziness

joint or muscle pain

unsteadiness

vomiting

confusion

leg cramps

depression

headache

blurred vision

stomach pain

dry mouth

swollen tongue

diarrhea, edema

fluid retention

nausea

ringing in your ears

Less common but more serious side effects during taking Actinerval:

allergy reactions (urticaria, breathing difficulties, rash, and eruption)

sore throat

abnormal weakness

problems with urinating

aches of body

swelling

roblems with appetite

low fever

jaundice

clay-colored stools

fever

easy bruising or bleeding

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Actinerval (Tegretol) Contra-indications

Do not take Actinerval if you are allergic to Actinerval components.

Do not take Actinerval if you ever had an allergy to antidepressants such as desipramine (Norpramin), amitriptyline (Elavil), imipramine (Tofranil), clomipramine (Anafranil), doxepin (Sinequan), nortriptyline (Pamelor).

Do not take Actinerval if you are pregnant, planning to become pregnant, or are breast-feeding.

Do not take Actinerval if you are taking such medicines as selegiline (such as Eldepryl, Emsam), tranylcypromine (such as Parnate), isocarboxazid (such as Marplan)), MAO inhibitor (phenelzine (such as Nardil), sleeping drugs.

Be careful if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.

Be careful with Actinerval if you suffer from or have a history of liver or heart disease; mental illness; lupus, glaucoma, bone marrow suppression.

Elderly people should be very careful with Actinerval.

Be careful with sunlight. Try to protect your skin.

If you experience drowsiness and dizziness while taking Actinerval you should avoid any activities such as driving or operating machinery.

Avoid alcohol while taking Actinerval.

It can be dangerous to stop Actinerval taking suddenly.

Actinerval (Tegretol) Frequently asked questions

Q: What is Actinerval?

A: It is anticonvulsant.

Q: What is Actinerval target?

A: Actinerval target is the treatment of simple and complex forms of seizure. It is also used to treat nerve pain of the face such as trigeminal neuralgia and diabetic neuropathy, bipolar disorder.

Q: How does Actinerval work?

A: Actinerval is acting by reducing the action of nerve which causes pain and seizures.

Q: What should I do in case of dose missing?

A: In case of dose missing you should take your tablet as soon as possible. Do not take double dosage. And if it is right time for the next dosage you should continue your regular schedule of Actinerval taking.

Q: Why should I not use Actinerval?

A: Do not take Generic Topamax if you are allergic to Generic Topamax components. Do not take Generic Topamax if you are pregnant, planning to become pregnant, or are breast-feeding.

Q: Can Actinerval cause allergic reaction?

A: Actinerval allergy reactions are urticaria, breathing difficulties, rash, and eruption.

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Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Product Description Common use Doxycyline is a synthetic broad-spectrum antibiotic derived from tetracycline and used to treat many different bacterial infections, such as infections of urinary tract, acne, gonorrhea, chlamydiosis, periodontitis (gum disease), blemishes, bumps, and acne-like lesions caused by rosacea.

Dosage and directions This medication should be taken after a meal with a big glass of water to decrease irritation of esophagus. Daily dose should be taken as a single dose or divided in two (12 hours between each one). Do not take it in larger amounts or continue to take it after the administered period. Certain brands of this medication cannot be used with dairy products. Do not crush, break, or open a delayed-release capsule, eat the pill whole. If it is an oral suspension shake it before use and measure with special measuring spoon. Never take this drug if it is expired as it may damage your kidney.

Precautions Usage of Doxycycline during growth of teeth may result in their permanent color change. Avoid exposure of your body to prolonged UV radiation during treatment and 4-5 days after it. If long treatment with this medication is prescribed a regular monitoring of peripheral blood cell content, liver function tests and determination of nitrogen and urea in serum are required.

Contraindications Hypersensitivity to Doxycycline and tetracyclines, pregnancy (second half of the term), breastfeeding, infancy (for children younger than 9 y. o.), leucopenia, porphyria, severe liver failure.

Possible side effect Side effects caused by Doxycycline may appear as headache, dizziness, blurred vision, fever, chills, body aches, red skin rash, pale or yellowed skin, dark colored urine, severe pain in upper stomach, loss of appetite, jaundice, easy bruising or bleeding. Contact your doctor if you experience severe effects listed above.

Drug interaction Co-administration with aluminum, magnesium, or calcium based antacids is not recommended as Doxycyline absorption maybe slowered. Minerals (such as calcium or iron) or with bismuth subsalicylate have the same effect. Doxycycline is reported to enhance the activity of warfarin. Phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (such as phenobarbital) may enhance the metabolism of Doxycycline.

Missed dose Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose In case of serious and persistent nausea, vomiting, and diarrhea consult your doctor.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.



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Sinova, Sinova

Sinova

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Nu-Metoclopramide, Nu-Metoclopramide

metoclopramide hydrochloride

Contraindications

• Hypersensitivity to drug • Pheochromocytoma • Parkinson's disease • Suspected GI obstruction, perforation, or hemorrhage • History of seizure disorders

Precautions

Use cautiously in: • diabetes mellitus, renal dysfunction • history of depression • elderly patients • pregnant or breastfeeding patients • children.

Administration

• Mix oral solution with water, juice, carbonated beverage, or semisolid food (such as applesauce or pudding) just before administration. • Remove orally disintegrating tablets with dry hands immediately before administering. After removing, place tablet on patient's tongue, where it will dissolve in approximately 1 minute. Tell patient to swallow saliva. • Give I. M. or direct I. V. without further dilution. • Administer low doses (10 mg or less) by direct I. V. injection slowly over 2 minutes. (Rapid injection may cause intense anxiety and restlessness followed by drowsiness.) • For I. V. infusion, dilute with 50 ml of 5% dextrose in 0.9% sodium chloride solution, 5% dextrose in 0.45% sodium chloride solution, or lactated Ringer's solution. Infuse over at least 15 minutes.

Adverse reactions

CNS: drowsiness, restlessness, anxiety, depression, irritability, fatigue, lassitude, insomnia, tardive dyskinesia, parkinsonian-like reactions, extrapyramidal reactions, akathisia, dystonia

CV: hypertension, hypotension, arrhythmias, neuroleptic malignant syndrome

GI: nausea, constipation, diarrhea, dry mouth

Interactions

Drug-drug. Anticholinergics, opioids: antagonism of metoclopramide's GI motility effect

Antidepressants, antihistamines, other CNS depressants (such as opioids, sedative-hypnotics ): additive CNS depression

Cimetidine, digoxin: decreased blood levels of these drugs

General anesthestics: exaggerated hypotension

Haloperidol, phenothiazines: increased risk of extrapyramidal reactions

Levodopa: decreased metoclopramide efficacy

MAO inhibitors: increased catecholamine release

Drug-diagnostic tests. Aldosterone, prolactin: increased levels

Drug-behaviors. Alcohol use: increased blood alcohol level, increased CNS depression

Patient monitoring

• Monitor blood pressure during I. V. administration. • Stay alert for depression and other adverse CNS effects.

☞ Watch for extrapyramidal reactions, which usually occur within first 24 to 48 hours of therapy. To reverse these symptoms, give diphenhydramine 50 mg I. M. or benztropine 1 to 2 mg I. M. as prescribed. • Check for development of parkinsonian-like symptoms, which may occur within first 6 months of therapy and usually subside within 2 to 3 months after withdrawal.

☞ With long-term use, assess patient for tardive dyskinesia and discontinue drug if signs or symptoms of tardive dyskinesia develop. Avoid treatment for longer than 12 weeks in all but rare cases in which therapeutic benefit outweighs risk of developing tardive dyskinesia.

☞ Monitor patient closely for signs and symptoms of neuroleptic malignant syndrome (hyperthermia, muscle rigidity, altered consciousness, and evidence of autonomic instability [irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac arrhythmias]); immediately discontinue drug if these symptoms occur. • In diabetic patient, stay alert for gastric stasis. Insulin dosage may need to be adjusted.

Patient teaching

• Tell patient to take 30 minutes before meals. • Tell patient taking orally disintegrating tablets to remove tablet with dry hands immediately before use. Instruct patient to place tablet on tongue, where it will dissolve in approximately 1 minute, and then swallow saliva.

☞ Instruct patient to report involuntary movements of face, eyes, or limbs; muscle rigidity; altered consciousness; irregular pulse or blood pressure; rapid or irregular heartbeats; or excessive sweating. • Caution patient to avoid driving and other hazardous activities until drug's effects are known. • As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and behaviors mentioned above.

metoclopramide hydrochloride

a GI motility agent.

indications It is prescribed to stimulate motility of and increase the tone of gastric contractions of the upper GI tract and to prevent emesis.

contraindications A history of seizures; concomitant use of drugs that cause extrapyramidal reactions; pheochromocytoma; GI hemorrhage, obstruction, or perforation; or known hypersensitivity to this drug prohibits its use.

adverse effects Among the more serious adverse effects are extrapyramidal reactions, usually in children, and GI disturbances. Drowsiness and allergic reactions and rash also may occur.

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Salbutes, A Yucatecan Tortilla Recipe, Salbutis

Salbutes, a Yucatecan Tortilla

Salbutes are delicious little snacks which typify Mayan and Yucatecan cooking. They can be made with a variety of toppings, I've listed the most popular ones. Salbutes can also be served as part of a luncheon menu. Before making these, note that the pickled red onions (so famous in Yucatan cooking) do require a standing time of several hours. It's best to make them a day in advance, they keep for about a week in the refrigerator. For a great casual lunch, try serving salbutes with a bowl of bean soup and a fresh fruit salad. It's a popular combination served at the Mayan Beach Garden in Yucatan where this recipe comes from.

Ingredients Nutrition



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Colimix® Syrup, Colimix

Colimix® syrup

Xepa SP manufactures wide range of pharmaceutical products which includes colimix® syrup. It belongs to antispasmodics products category. Features: antispasmodic that helps to bring your digestive system back to normal, relieves infant colic, wind (flatulence) and abdominal discomfort, for adults and children. Form / Packaging: each 5ml contains simethicone 50mg, dicyclomine hcl 5mg, orange colour, sweetly flavoured, pack of 90ml and 120m.

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Common use Atorvastatin is a cholesterol-lowering used to treat high cholesterol or to lower the risk of stroke, heart attack or other heart complications in patients with coronary heart disease or second type of diabetes. Atorvastatin helps to clear harmful low-density lipoprotein cholesterol out of the blood and by limiting the body's ability to form new LDL cholesterol. Thus it can help prevent hardening of the arteries and heart disease, conditions that can lead to vascular disease, heart attack, stroke.

Dosage and direction Take it orally once a day with or without food. Atorvastatine should be taken with full glass of water. The common dose for adults is 10 mg once daily. The common dose for children from 10 to 17 years of age is 10 mg once daily. Using Atorvastatin in children less than 10 years of age is not recommended and dose must be determined by your family doctor.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.

Precautions People with diabetes, underactive thyroid glands, kidney disease, or muscle disease sometimes need additional tests before or during atorvastatin therapy since dosage adjustments may be required. Do not use large amounts of alcohol while taking this drug because it can worsen the adverse effects of this medicine on the liver. Atorvastatin should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Atorvastatin before breast-feeding without doctor's permission.

Contraindications Atorvastatin is not allowed to people who have liver problems or unexplained abnormal liver function tests. Do not use it if you are taking an HIV protease inhibitor (eg, ritonavir), itraconazole, or mibefradil. Also Atorvastatin contraindicated if you are hypersensitive to any components of this medication, pregnancy or breast-feeding.

Possible side effect They may include all types of an allergic reaction. Also the most possible side effects include: muscle pain, tenderness, or weakness with fever or flu symptoms; or nausea, clay-colored stools, stomach pain, low fever, jaundice, loss of appetite, dark urine. Less serious include: mild nausea or stomach pain, stomach upset, heartburn; constipation, bloating, gas; stuffy nose; itching, skin rash; headache. If you experience one of them stop using Atorvastatin and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction Atrovastatin interact with the following drugs: digoxin; erythromycin or clarithromycin; gemfibrozil or fenofibrate; niacin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Symptoms of Atorvastatin are not known well but most possible of them include a severe drop in blood pressure and a faster heartbeat. If you experience one of them or any unusual symptoms, call your doctor immediately.

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use Atorvastatin is a cholesterol-lowering used to treat high cholesterol or to lower the risk of stroke, heart attack or other heart complications in patients with coronary heart disease or second type of diabetes. Atorvastatin helps to clear harmful low-density lipoprotein cholesterol out of the blood and by limiting the body's ability to form new LDL cholesterol. Thus it can help prevent hardening of the arteries and heart disease, conditions that can lead to vascular disease, heart attack, stroke.

Dosage and direction Take it orally once a day with or without food. Atorvastatine should be taken with full glass of water. The common dose for adults is 10 mg once daily. The common dose for children from 10 to 17 years of age is 10 mg once daily. Using Atorvastatin in children less than 10 years of age is not recommended and dose must be determined by your family doctor.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.

Precautions People with diabetes, underactive thyroid glands, kidney disease, or muscle disease sometimes need additional tests before or during atorvastatin therapy since dosage adjustments may be required. Do not use large amounts of alcohol while taking this drug because it can worsen the adverse effects of this medicine on the liver. Atorvastatin should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Atorvastatin before breast-feeding without doctor's permission.

Contraindications Atorvastatin is not allowed to people who have liver problems or unexplained abnormal liver function tests. Do not use it if you are taking an HIV protease inhibitor (eg, ritonavir), itraconazole, or mibefradil. Also Atorvastatin contraindicated if you are hypersensitive to any components of this medication, pregnancy or breast-feeding.

Possible side effect They may include all types of an allergic reaction. Also the most possible side effects include: muscle pain, tenderness, or weakness with fever or flu symptoms; or nausea, clay-colored stools, stomach pain, low fever, jaundice, loss of appetite, dark urine. Less serious include: mild nausea or stomach pain, stomach upset, heartburn; constipation, bloating, gas; stuffy nose; itching, skin rash; headache. If you experience one of them stop using Atorvastatin and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction Atrovastatin interact with the following drugs: digoxin; erythromycin or clarithromycin; gemfibrozil or fenofibrate; niacin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Symptoms of Atorvastatin are not known well but most possible of them include a severe drop in blood pressure and a faster heartbeat. If you experience one of them or any unusual symptoms, call your doctor immediately.

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use Atorvastatin is a cholesterol-lowering used to treat high cholesterol or to lower the risk of stroke, heart attack or other heart complications in patients with coronary heart disease or second type of diabetes. Atorvastatin helps to clear harmful low-density lipoprotein cholesterol out of the blood and by limiting the body's ability to form new LDL cholesterol. Thus it can help prevent hardening of the arteries and heart disease, conditions that can lead to vascular disease, heart attack, stroke.

Dosage and direction Take it orally once a day with or without food. Atorvastatine should be taken with full glass of water. The common dose for adults is 10 mg once daily. The common dose for children from 10 to 17 years of age is 10 mg once daily. Using Atorvastatin in children less than 10 years of age is not recommended and dose must be determined by your family doctor.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.

Precautions People with diabetes, underactive thyroid glands, kidney disease, or muscle disease sometimes need additional tests before or during atorvastatin therapy since dosage adjustments may be required. Do not use large amounts of alcohol while taking this drug because it can worsen the adverse effects of this medicine on the liver. Atorvastatin should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Atorvastatin before breast-feeding without doctor's permission.

Contraindications Atorvastatin is not allowed to people who have liver problems or unexplained abnormal liver function tests. Do not use it if you are taking an HIV protease inhibitor (eg, ritonavir), itraconazole, or mibefradil. Also Atorvastatin contraindicated if you are hypersensitive to any components of this medication, pregnancy or breast-feeding.

Possible side effect They may include all types of an allergic reaction. Also the most possible side effects include: muscle pain, tenderness, or weakness with fever or flu symptoms; or nausea, clay-colored stools, stomach pain, low fever, jaundice, loss of appetite, dark urine. Less serious include: mild nausea or stomach pain, stomach upset, heartburn; constipation, bloating, gas; stuffy nose; itching, skin rash; headache. If you experience one of them stop using Atorvastatin and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction Atrovastatin interact with the following drugs: digoxin; erythromycin or clarithromycin; gemfibrozil or fenofibrate; niacin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.

Symptoms of Atorvastatin are not known well but most possible of them include a severe drop in blood pressure and a faster heartbeat. If you experience one of them or any unusual symptoms, call your doctor immediately.

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.



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Metro Detroit - Tourism And Travel, Dertolit

Healthy food in a fun, fast way. Choose from a variety of ingredients to add to your 7 Greens salad. With no freezer in-house, you can be sure your creation is fresh, fresh, fresh.

Cobo Center is Detroit’s premier convention space. Explore Cobo and the many other available meeting venues in and around the city.

Detroit's mobile visitor center is serving up the city’s best attractions at every stop. Find out where the D-Rover will appear around town this summer.

Warmer weather brings a whole new set of activities to enjoy in metro Detroit. Here are a few suggestions to get you started.

The FREE D Discount Pass saves you 20% or more on entrance to Detroit’s best-loved attractions, including The Henry Ford. This year the Discount Pass features five new attractions. What are you waiting for? Sign up!

Upcoming Events

Michigan Renaissance Festival

Music, sword swallowing, comedy, fire juggling and, of course, the costumes of a bygone era all deliberately, magically on display. Aug. 20-Oct. 2.

City Sculpture Jamboree

Performances by Ethan Daniel Davidson and Botanical Fortress, along with vendors Jim Gibbons, AVS Sound, Guerrilla Food, Dilla Delights, Motor City Brewing Works and Drifter Coffee. Sept. 30.

Tour de Troit Ride

Explore Detroit’s historic and beautiful areas from your bike during this Motown streets takeover. As the city’s largest cycling event, the ride raises biking awareness and publicizes greenways. Sept. 17.

Find Events

Navigating the D

The metro Detroit area has five distinct destination districts, perfect for tourism and travel — everything from a lively urban vibe to wide-open scenic spaces. Here, we work hard and play hard.

To learn more about each area’s unique personality, click on a metro Detroit destination district to the left and let your exploration begin.

Visit the D Blog

The Detroit Free Press/Talmer Bank Marathon takes place Oct. 15 and 16. Whether it's burgers.

Often times, traveling to another city for a conference means never seeing the outside of.

Metro Detroit has its own O. C. Oakland County. With premier shopping, amazing restaurants and plenty.

Say it with us - Oktoberfest. Trust us, when a visit to Belgium isn't in.



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Oftacin

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Buy Pain Relief - Tanfedin (Brand Name Tegretol) Online - Order Carbamazepine - Purchase Pain Relief

Tegretol (carbamazepine) is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain. Tegretol is used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Carbamazepine is also used to treat bipolar disorder. Tegretol may also be used for purposes not listed in this medication guide.

Take Tegretol exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release Tegretol tablet. Swallow the pill whole. Breaking the pill would cause too much of the drug to be released at one time.

Shake the Tegretol oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and call your doctor promptly if this medicine seems to stop working as well in preventing your seizures. Tegretol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.

To be sure Tegretol is not causing harmful effects, your blood cells and kidney function may need to be tested often. Do not miss any follow up visits to your doctor for blood or urine tests. Your doctor may also recommend having your eyes checked regularly while you are taking this medicine.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using this medicine suddenly. Wear a medical alert tag or carry an ID card stating that you take Tegretol. Any medical care provider who treats you should know that you take seizure medication.

Store this medicine at room temperature away from moisture, heat, and light.

Active Ingredient: Carbamazepine

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction. Seek emergency medical attention if you have a fever, sore throat, headache and skin pain, followed by a red or purple skin rash that spreads and causes blistering and peeling.

You should not take Tegretol if you have a history of bone marrow suppression, if you are also taking nefazodone, or if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Tegretol may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking Tegretol for seizures. Do not start or stop taking Tegretol during pregnancy without your doctor's advice.

Before you take Tegretol, tell your doctor if you have heart disease, high blood pressure, high cholesterol, liver or kidney disease, glaucoma, a thyroid disorder, lupus, porphyria, or a history of mental illness or psychosis.

You may have thoughts about suicide while taking Tegretol. Your doctor will need to check you at regular visits. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

There are many other drugs that can interact with Tegretol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using Tegretol suddenly.

Do not use Tegretol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. You should not take Tegretol if you are allergic to carbamazepine, or if you have:

a history of bone marrow suppression

if you are also taking nefazodone; or

if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Important safety information:

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

To make sure you can safely take Tegretol, tell your doctor if you have any of these other conditions:

heart disease, high blood pressure, high cholesterol or triglycerides;

liver or kidney disease;

a thyroid disorder;

a history of mental illness or psychosis.

Patients of Asian ancestry may have a higher risk of developing a rare but serious skin reaction to Tegretol. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

You may have thoughts about suicide while taking Tegretol. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed. Seizure control is very important during pregnancy. The benefit of preventing seizures may outweigh any risks posed by taking Tegretol. Follow your doctor's instructions about taking Tegretol while you are pregnant.

FDA pregnancy category D. Tegretol may cause harm to an unborn baby. Do not start taking this medcine without telling your doctor if you are pregnant or planning to become pregnant. Use effective birth control while you are taking this medicine. Although Tegretol may harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. If you become pregnant while taking Tegretol, do not stop taking the medicine without your doctor's advice.

Carbamazepine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using Tegretol. Carbamazepine can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Tegretol.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It can increase some of the side effects of Tegretol, and can also increase your risk of seizures.

Avoid exposure to sunlight or tanning beds. Tegretol can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Grapefruit and grapefruit juice may interact with Tegretol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Tegretol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

pale skin, feeling light-headed, rapid heart rate, trouble concentrating;

fever, chills, sore throat, mouth and throat ulcers;

easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness;

confusion, agitation, vision problems, hallucinations;

feeling short of breath, swelling of your ankles or feet;

urinating less than usual;

jaundice (yellowing of the skin or eyes); or

severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious Tegretol side effects may include:

feeling dizzy, drowsy, or unsteady;

nausea, vomiting, diarrhea, constipation, stomach pain;

headache, ringing in your ears;

dry mouth, swollen tongue; or

joint or muscle pain, leg cramps.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



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Feldene is indicated for relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis. Feldene is an NSAID. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Use Feldene as directed by your doctor.

Take Feldene by mouth. It may be taken with food if it upsets your stomach. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.

Take Feldene with a full glass of water (8 oz/240 mL) as directed by your doctor.

If you miss a dose of Feldene and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Feldene.

Store Feldene at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Feldene out of the reach of children and away from pets.

Active Ingredient: Piroxicam.

Do NOT use Feldene if:

you are allergic to any ingredient in Feldene

you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

you have recently had or will be having bypass heart surgery

you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Feldene. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)

if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation

if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

if you have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse.

Some medicines may interact with Feldene. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased

Probenecid because it may increase the risk of Feldene's side effects

Cyclosporine, hydantoins (eg, phenytoin), lithium, methotrexate, quinolones (eg, ciprofloxacin), sulfonamides (eg, sulfamethoxazole), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Feldene

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Feldene

This may not be a complete list of all interactions that may occur. Ask your health care provider if Feldene may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Feldene may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Feldene with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Serious stomach ulcers or bleeding can occur with the use of Feldene. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Feldene with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Feldene is an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist.

Do not take aspirin while you are using Feldene unless your doctor tells you to.

Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

Use Feldene with caution in the elderly; they may be more sensitive to its effects, including stomach bleeding and kidney problems.

Feldene should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: Feldene may harm the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Feldene while you are pregnant. Feldene is found in breast milk. Do not breastfeed while you are taking Feldene.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; dizziness; gas; headache; heartburn; nausea; stomach upset.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.



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Product Description

Lynoral (Ethinyl Estradiol) is an oral contraceptive remedy. It is a synthetic oestrogen similar to estradiol produced in the ovaries. Chiefly it is used to prevent pregnancy by inhibiting ovulation. It averts conception by hampering a transport of sperm or eggs to the uterus. This medication prevents symptoms of menopause such as hot flashes, vaginal irritation and dryness. It is also used in the treatment of breast and prostate cancer.

Determine with your doctor a proper dose and intake schedule that best suits your case. Take this medication exactly as your doctor has prescribed it. You must carefully follow all directions. Avoid exceeding your dose, give up taking the medication without your doctor’s permission or taking it longer than was advised.

Immediately notify your doctor in case you are pregnant, plan to be pregnant or nursing a baby. A category of smoking patients or women that are over 35 years old are more inclined to suffer from an adverse drug response.

This medication is contraindicated in women who are pregnant or plan to be pregnant as it may cause harm to the unborn child.

Possible side effect

The most common side effects include nausea, retching, digestive upsets (diarrhea), giddiness, mastalgia, fatigue, headache, mental or mood changes, depression, chest pain, sleeping disorder, hair loss, allergic reaction (urticaria), and vaginitis. More severe side effects are: migraines, abdominal cramps, icterus, uterine bleeding, legs or groin pain, breathing trouble.

Lynoral may interact with a class of medicines used to treat hypertension, diuretics. Avoid using this medication concurrently with antibiotics and anticonvulsants as it may reduce oral contraceptives’ effectiveness.

In case you have missed to take a dose of this medication, take it as soon as possible and then resume your regular dosing schedule. Thereby, it is possible to take 2 pills per day. Use any alternative contraceptive remedies (spermicides, condoms) during a week in case you have missed two intakes in succession.

If you suspect you have used too much of this medication, seek emergency medical attention right away. You must do this even if symptoms of discomfort or poisoning haven’t been indicated at once. You may need urgent medical attention. The most common symptoms of overdose include nausea, vomiting, vertigo, faintness.

Store this product in a dry tight container away from sunlight, heat and moisture at room temperature between 15-30 C (or 59-86 F). Do not store it in the bathroom. Keep this product out of the reach of children and pets.

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.

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Alphamox (Amoxycillin) - United Pharmacies, Alfamox

Alphamox

Description

Alphamox (Amoxycillin) is a penicillin-like antibiotic used to treat certain infections caused by bacteria, such as pneumonia; bronchitis; venereal disease (VD); and ear, lung, nose, urinary tract, and skin infections. It also is used before some surgery or dental work to prevent infection. Antibiotics will not work for colds, flu, or other viral infections.

Dosage and Administration

Capsules should be swallowed whole and taken with a full glass of water. Continue to take Alphamox (Amoxycillin) even if you feel well. Do not stop taking it without talking to your physician.

Although side effects from Alphamox (Amoxycillin) are not common, they can occur. Tell your physician if any of these symptoms are severe or do not go away: upset stomach, diarrhea, vomiting, mild skin rash. If you experience any of the following symptoms, call your physician immediately: severe skin rash, itching, hives, difficulty breathing or swallowing, wheezing, vaginal infection.



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Palacimol, Palacimol

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Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Degranol, Carbamazepine, Degranol

Degranol

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Carbamazepine should not be used in patients with a history of previous bone marrow depression, hypersensitivity to the drug, or known sensitivity to any of the tricyclic compounds, such as amitriptyline, desipramine, imipramine, protriptyline, nortriptyline, etc. Likewise, on theoretical grounds its use with monoamine oxidase inhibitors is not recommended. Before administration of Carbamazepine, MAO inhibitors should be discontinued for a minimum of 14 days, or longer if the clinical situation permits. Coadministration of Carbamazepine and nefazodone may result in insufficient plasma concentrations of nefazodone and its active metabolite to achieve a therapeutic effect. Coadministration of Carbamazepine with nefazodone is contraindicated.

If adverse reactions are of such severity that the drug must be discontinued, the physician must be aware that abrupt discontinuation of any anticonvulsant drug in a responsive epileptic patient may lead to seizures or even status epilepticus with its life-threatening hazards. The most severe adverse reactions have been observed in the hemopoietic system and skin, the liver and the cardiovascular system. The most frequently observed adverse reactions, particularly during the initial phases of therapy, are dizziness, drowsiness, unsteadiness, nausea, and vomiting. To minimize the possibility of such reactions, therapy should be initiated at the low dosage recommended. The following additional adverse reactions have been reported: Hemopoietic System: Aplastic anemia, agranulocytosis, pancytopenia, bone marrow depression, thrombocytopenia, leukopenia, leukocytosis, eosinophilia, acute intermittent porphyria. Skin: Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS), pruritic and erythematous rashes, urticaria, photosensitivity reactions, alterations in skin pigmentation, exfoliative dermatitis, erythema multiforme and nodosum, purpura, aggravation of disseminated lupus erythematosus, alopecia, and diaphoresis. In certain cases, discontinuation of therapy may be necessary. Isolated cases of hirsutism have been reported, but a causal relationship is not clear. Cardiovascular System: Congestive heart failure, edema, aggravation of hypertension, hypotension, syncope and collapse, aggravation of coronary artery disease, arrhythmias and AV block, thrombophlebitis, thromboembolism, and adenopathy or lymphadenopathy. Some of these cardiovascular complications have resulted in fatalities. Myocardial infarction has been associated with other tricyclic compounds. Liver: Abnormalities in liver function tests, cholestatic and hepatocellular jaundice, hepatitis; very rare cases of hepatic failure. Pancreatic: Pancreatitis. Respiratory System: Pulmonary hypersensitivity characterized by fever, dyspnea, pneumonitis, or pneumonia. Genitourinary System: Urinary frequency, acute urinary retention, oliguria with elevated blood pressure, azotemia, renal failure, and impotence. Albuminuria, glycosuria, elevated BUN, and microscopic deposits in the urine have also been reported. Testicular atrophy occurred in rats receiving Carbamazepine orally from 4 to 52 weeks at dosage levels of 50 to 400 mg/kg/day. Additionally, rats receiving Carbamazepine in the diet for 2 years at dosage levels of 25, 75, and 250 mg/kg/day had a dose? related incidence of testicular atrophy and aspermatogenesis. In dogs, it produced a brownish discoloration, presumably a metabolite, in the urinary bladder at dosage levels of 50 mg/kg and higher. Relevance of these findings to humans is unknown. Nervous System: Dizziness, drowsiness, disturbances of coordination, confusion, headache, fatigue, blurred vision, visual hallucinations, transient diplopia, oculomotor disturbances, nystagmus, speech disturbances, abnormal involuntary movements, peripheral neuritis and paresthesias, depression with agitation, talkativeness, tinnitus, and hyperacusis. There have been reports of associated paralysis and other symptoms of cerebral arterial insufficiency, but the exact relationship of these reactions to the drug has not been established. Isolated cases of neuroleptic malignant syndrome have been reported with concomitant use of psychotropic drugs. Digestive System: Nausea, vomiting, gastric distress and abdominal pain, diarrhea, constipation, anorexia, and dryness of the mouth and pharynx, including glossitis and stomatitis. Eyes: Scattered punctate cortical lens opacities, as well as conjunctivitis, have been reported. Although a direct causal relationship has not been established, many phenothiazines and related drugs have been shown to cause eye changes. Musculoskeletal System: Aching joints and muscles, and leg cramps. Metabolism: Fever and chills. Inappropriate antidiuretic hormone (ADH) secretion syndrome has been reported. Cases of frank water intoxication, with decreased serum sodium (hyponatremia) and confusion, have been reported in association with Carbamazepine use. Decreased levels of plasma calcium have been reported. Other: Multi-organ hypersensitivity reactions occurring days to weeks or months after initiating treatment have been reported in rare cases. Signs or symptoms may include, but are not limited to fever, skin rashes, vasculitis, lymphadenopathy, disorders mimicking lymphoma, arthralgia, leukopenia, eosinophilia, hepato-splenomegaly and abnormal liver function tests. These signs and symptoms may occur in various combinations and not necessarily concurrently. Signs and symptoms may initially be mild. Various organs, including but not limited to, liver, skin, immune system, lungs, kidneys, pancreas, myocardium, and colon may be affected. Isolated cases of a lupus erythematosus-like syndrome have been reported. There have been occasional reports of elevated levels of cholesterol, HDL cholesterol, and triglycerides in patients taking anticonvulsants. A case of aseptic meningitis, accompanied by myoclonus and peripheral eosinophilia, has been reported in a patient taking Carbamazepine in combination with other medications. The patient was successfully dechallenged, and the meningitis reappeared upon rechallenge with Carbamazepine.

Clinically meaningful drug interactions have occurred with concomitant medications and include, but are not limited to, the following: Agents That May Affect Carbamazepine Plasma Levels CYP 3A4 inhibitors inhibit Carbamazepine metabolism and can thus increase plasma Carbamazepine levels. Drugs that have been shown, or would be expected, to increase plasma Carbamazepine levels include: cimetidine, danazol, diltiazem, macrolides, erythromycin, troleandomycin, clarithromycin, fluoxetine, fluvoxamine, nefazodone, loratadine, terfenadine, isoniazid, niacinamide, nicotinamide, propoxyphene, azoles (e. g. ketoconazole, itraconazole, fluconazole), acetazolamide, verapamil, grapefruit juice, protease inhibitors, valproate.1 CYP 3A4 inducers can increase the rate of Carbamazepine metabolism. Drugs that have been shown, or that would be expected, to decrease plasma Carbamazepine levels include: cisplatin, doxorubicin HCl, felbamate,2 rifampin, phenobarbital, phenytoin, primidone, methsuximide, theophylline. When Carbamazepine is given with drugs that can increase or decrease Carbamazepine levels, close monitoring of Carbamazepine levels is indicated and dosage adjustment may be required. Effect of Carbamazepine on Plasma Levels of Concomitant Agents Increased levels: clomipramine HCl, phenytoin, primidone Carbamazepine induces hepatic CYP activity. Carbamazepine causes, or would be expected to cause, decreased levels of the following: acetaminophen, alprazolam, dihydropyridine calcium channel blockers (e. g. felodipine), cyclosporine, corticosteroids (e. g. prednisolone, dexamethasone), clonazepam, clozapine, dicumarol, doxycycline, ethosuximide, haloperidol, itraconazole, lamotrigine, levothyroxine, methadone, methsuximide, midazolam, olanzapine, oral and other hormonal contraceptives, oxcarbazepine, phensuximide, phenytoin, praziquantel, protease inhibitors, risperidone, theophylline, tiagabine, topiramate, tramadol, tricyclic antidepressants (e. g. imipramine, amitriptyline, nortriptyline), valproate, warfarin, ziprasidone, zonisamide. In concomitant use with Carbamazepine, dosage adjustment of the above agents may be necessary. Coadministration of Carbamazepine with nefazodone results in insufficient plasma concentrations of nefazodone and its active metabolite to achieve a therapeutic effect. Coadministration of Carbamazepine with nefazodone is contraindicated. Concomitant administration of Carbamazepine and lithium may increase the risk of neurotoxic side effects. Alterations of thyroid function have been reported in combination therapy with other anticonvulsant medications. Concomitant use of Carbamazepine with hormonal contraceptive products (e. g. oral, and levonorgestrel subdermal implant contraceptives) may render the contraceptives less effective because the plasma concentrations of the hormones may be decreased. Breakthrough bleeding and unintended pregnancies have been reported. Alternative or back-up methods of contraception should be considered. Carcinogenesis, Mutagenesis, Impairment of Fertility Carbamazepine, when administered to Sprague-Dawley rats for two years in the diet at doses of 25, 75, and 250 mg/kg/day, resulted in a dose-related increase in the incidence of hepatocellular tumors in females and of benign interstitial cell adenomas in the testes of males. Carbamazepine must, therefore, be considered to be carcinogenic in Sprague-Dawley rats. Bacterial and mammalian mutagenicity studies using Carbamazepine produced negative results. The significance of these findings relative to the use of Carbamazepine in humans is, at present, unknown. Usage in Pregnancy Teratogenic Effects Pregnancy category D Labor and Delivery The effect of Carbamazepine on human labor and delivery is unknown. Nursing Mothers Carbamazepine and its epoxide metabolite are transferred to breast milk. The ratio of the concentration in breast milk to that in maternal plasma is about 0.4 for Carbamazepine and about 0.5 for the epoxide. The estimated doses given to the newborn during breast feeding are in the range of 2 to 5 mg daily for Carbamazepine and 1 to 2 mg daily for the epoxide. Because of the potential for serious adverse reactions in nursing infants from Carbamazepine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use Substantial evidence of Carbamazepine’s effectiveness for use in the management of children with epilepsy is derived from clinical investigations performed in adults and from studies in several in vitro systems which support the conclusion that (1) the pathogenetic mechanisms underlying seizure propagation are essentially identical in adults and children, and (2) the mechanism of action of Carbamazepine in treating seizures is essentially identical in adults and children. Taken as a whole, this information supports a conclusion that the generally accepted therapeutic range of total Carbamazepine in plasma (i. e. 4 to 12 mcg/mL) is the same in children and adults. The evidence assembled was primarily obtained from short-term use of Carbamazepine. The safety of Carbamazepine in children has been systematically studied up to 6 months. No longer-term data from clinical trials is available. Geriatric Use No systematic studies in geriatric patients have been conducted.

General Before initiating therapy, a detailed history and physical examination should be made. Carbamazepine should be used with caution in patients with a mixed seizure disorder that includes atypical absence seizures, since in these patients Carbamazepine has been associated with increased frequency of generalized convulsions. Therapy should be prescribed only after critical benefit-to-risk appraisal in patients with a history of cardiac conduction disturbance, including second and third degree AV heart block; cardiac, hepatic, or renal damage; adverse hematologic or hypersensitivity reaction to other drugs, including reactions to other anticonvulsants; or interrupted courses of therapy with Carbamazepine. Hepatic effects, ranging from slight elevations in liver enzymes to rare cases of hepatic failure have been reported. In some cases, hepatic effects may progress despite discontinuation of the drug. Multiorgan hypersensitivity reactions occurring days to weeks or months after initiating treatment have been reported in rare cases. Discontinuation of Carbamazepine should be considered if any evidence of hypersensitivity develops. Information for Patients Patients should be made aware of the early toxic signs and symptoms of a potential hematologic problem, as well as dermatologic, hypersensitivity or hepatic reactions. These symptoms may include, but are not limited to, fever, sore throat, rash, ulcers in the mouth, easy bruising, lymphadenopathy and petechial or purpuric hemorrhage, and in the case of liver reactions, anorexia, nausea/vomiting, or jaundice. The patient should be advised that, because these signs and symptoms may signal a serious reaction, that they must report any occurrence immediately to a physician. In addition, the patient should be advised that these signs and symptoms should be reported even if mild or when occurring after extended use. Patients, their caregivers, and families should be counseled that AEDs, including Carbamazepine, may increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm. Behaviors of concern should be reported immediately to healthcare providers. Carbamazepine may interact with some drugs. Therefore, patients should be advised to report to their doctors the use of any other prescription or nonprescription medications or herbal products. Caution should be exercised if alcohol is taken in combination with Carbamazepine therapy, due to a possible additive sedative effect. Since dizziness and drowsiness may occur, patients should be cautioned about the hazards of operating machinery or automobiles or engaging in other potentially dangerous tasks. Patients should be encouraged to enroll in the NAAED Pregnancy Registry if they become pregnant.

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Fields of color blend with great subtlety in Marinella Perosa's Sun and Sea series. Influenced early in her career by abstract expressionist Mark Rothko and Zen painting, the Italian artist focuses primarily on color. She approaches the canvas intuitively, using abstraction to synthesize experience and freeing color from dense layering to give it the lightness of simple, essential gesture. Hung individually or in groups, Perosa's paintings bring highly nuanced color to the home.

16.75"W x 21.75"H, overall.

High quality giclée print of original artwork.

Used for fine art reproductions, giclée printing involves transferring millions of tiny drops of ink to archival-quality paper, capturing the fine nuances of the original – including tone, shade and brushstrokes.

Set behind glass in a solid wood frame with a matte white painted finish.

Ready to hang with D-rings at the back.

Framed Artwork: 16.75"W x 1.5"D x 21.75"H.

Image: 15"W x 20"H

Weight: 5 lb.

Print: Made in USA.

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Shipping Information

This item is shipped from our warehouse by UPS to arrive within five business days of our receiving your order.

Shipping Rates

The charge for all shipping is included in the flat-rate delivery fee listed below the item’s price.

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At Williams-Sonoma, we take great pride in the quality and craftsmanship of our products. If, within 30 days, you are not completely satisfied with your purchase for any reason, please return the item for an exchange or refund of the merchandise value. Final sale items ending in .97 or .99 cannot be returned. View Full Return Policy.

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Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs. com website is intended primarily for audiences in the United States and its territories. Indications, uses and warnings on Drugs. com patient information leaflets are derived from FDA product labels and may differ in countries outside the USA. Every effort has been made to ensure that the information provided on this page is accurate, up-to-date and complete, but no guarantee is made to that effect. Drugs. com does not endorse drugs, diagnose patients or recommend specific therapies. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice.

Chemical formula: C6H9N3O3 Drugbank ID: DB00916 ATC code(s): A01AB17, A02BD01, A02BD02, A02BD03, A02BD08, A02BD11, D06BX01, G01AF01, J01RA03, J01RA04, J01RA10, J01XD01, P01AB01, P01AB51

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Welcome to Allen at Steinbeck

Vision Statement

All San Jose Unified School District students are inspired and prepared to succeed in a global society.

Mission Statement

San Jose Unified School District’s mission is to eliminate the opportunity gap and provide every student with the finest 21st century education.

©2016 Allen at Steinbeck | 820 Steinbeck Drive, San Jose, CA 95123 | San Jose Ca, 95123 | 1-408-535-6205 Site Map | Website Disclaimer | Site by NetRaising Non-Discrimination Statement San Jose Unified School District does not discriminate on the basis of age, sex, sexual orientation, gender, gender identity, gender expression, ethnic group identification, race, ancestry, national origin, religion, marital or parental status, color, mental or physical disability, or on the basis of a person’s association with a person or group with one or more of these actual or perceived characteristics in its educational programs and activities or employment practices as required by Americans with Disabilities Act (ADA), Title VI of the Civil Rights Act of 1964, Title IX of the Education Amendments of 1972, the Age Discrimination Act of 1975, Section 504 or the Rehabilitation Act of 1973, and the Vocational Education Act of 1976. The lack of English language skills will not be a barrier to admission and participation in the District’s program s. Students, parents, employees, or others who wish further information about these regulations, or who wish to file a complaint, should contact the following persons: Director of Student Services, Dane Caldwell-Holden at 408-535-6080 ext. 13212; Assistant Superintendent of Human Resources, Dominic Bejarano at 408-535-6139 ext. 15015; Manager of Academic Supports, Michelle Herlth at 408-535-6008 ext. 14314; SJUSD 504 Coordinator, Yvonne King at 408 535-6195 ext. 13229.

Declaracion contra la discriminacion El Distrito Escolar Unificado de San Jose no discrimina por motivos de edad, sexo, orientacion sexual, genero, raza, identificacion de grupo etnico, linaje, religion, color de piel o discapacidad fisica o mental, en sus programas y actividades educativos ni en sus practicas de empleo, de acuerdo con los requisitos de la Ley de Estadounidenses con Discapacidades (ADA), el Titulo VI de la Ley de Derechos Civiles de 1964, el Titulo IX de las Enmiendas a la Educacion de 1972, la Ley de Discriminacion por Edad de 1975, Articulo 504 o la Ley de Rehabilitacion de 1973 y la Ley de Educacion Vocacional de 1976. La falta de destrezas en el idioma ingles no sera una barrera para ser admitido y participar en los programas del Distrito. Los estudiantes, padres de familia, empleados u otras personas que deseen mas informacion acerca de estos reglamentos o que deseen presentar una queja, deben ponerse en contacto con las siguientes personas: Director de Servicios Estudiantiles, Dane Caldwell-Holden, 408-535-6080 ext. 13212, Superintendente Auxiliar de Recursos Humanos, Dominic Bejarano, 408-535-6139 ext. 15015, Administradora de Apoyo Academico, Michelle Herlth 408-535-6608 ext. 14314, Coordinadora del Articulo 504 del Distrito, Yvonne King 408 535-6195 ext. 13229.

Welcome to Allen at Steinbeck

Vision Statement

All San Jose Unified School District students are inspired and prepared to succeed in a global society.

Mission Statement

San Jose Unified School District’s mission is to eliminate the opportunity gap and provide every student with the finest 21st century education.

©2016 Allen at Steinbeck | 820 Steinbeck Drive, San Jose, CA 95123 | San Jose Ca, 95123 | 1-408-535-6205 Site Map | Website Disclaimer | Site by NetRaising Non-Discrimination Statement San Jose Unified School District does not discriminate on the basis of age, sex, sexual orientation, gender, gender identity, gender expression, ethnic group identification, race, ancestry, national origin, religion, marital or parental status, color, mental or physical disability, or on the basis of a person’s association with a person or group with one or more of these actual or perceived characteristics in its educational programs and activities or employment practices as required by Americans with Disabilities Act (ADA), Title VI of the Civil Rights Act of 1964, Title IX of the Education Amendments of 1972, the Age Discrimination Act of 1975, Section 504 or the Rehabilitation Act of 1973, and the Vocational Education Act of 1976. The lack of English language skills will not be a barrier to admission and participation in the District’s program s. Students, parents, employees, or others who wish further information about these regulations, or who wish to file a complaint, should contact the following persons: Director of Student Services, Dane Caldwell-Holden at 408-535-6080 ext. 13212; Assistant Superintendent of Human Resources, Dominic Bejarano at 408-535-6139 ext. 15015; Manager of Academic Supports, Michelle Herlth at 408-535-6008 ext. 14314; SJUSD 504 Coordinator, Yvonne King at 408 535-6195 ext. 13229.

Declaracion contra la discriminacion El Distrito Escolar Unificado de San Jose no discrimina por motivos de edad, sexo, orientacion sexual, genero, raza, identificacion de grupo etnico, linaje, religion, color de piel o discapacidad fisica o mental, en sus programas y actividades educativos ni en sus practicas de empleo, de acuerdo con los requisitos de la Ley de Estadounidenses con Discapacidades (ADA), el Titulo VI de la Ley de Derechos Civiles de 1964, el Titulo IX de las Enmiendas a la Educacion de 1972, la Ley de Discriminacion por Edad de 1975, Articulo 504 o la Ley de Rehabilitacion de 1973 y la Ley de Educacion Vocacional de 1976. La falta de destrezas en el idioma ingles no sera una barrera para ser admitido y participar en los programas del Distrito. Los estudiantes, padres de familia, empleados u otras personas que deseen mas informacion acerca de estos reglamentos o que deseen presentar una queja, deben ponerse en contacto con las siguientes personas: Director de Servicios Estudiantiles, Dane Caldwell-Holden, 408-535-6080 ext. 13212, Superintendente Auxiliar de Recursos Humanos, Dominic Bejarano, 408-535-6139 ext. 15015, Administradora de Apoyo Academico, Michelle Herlth 408-535-6608 ext. 14314, Coordinadora del Articulo 504 del Distrito, Yvonne King 408 535-6195 ext. 13229.



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Efavirenz Oral Uses, Side Effects, Interactions, Pictures, Warnings - Dosing, Efavirenzum

efavirenz

GENERIC NAME(S): EFAVIRENZ

Uses

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer ) and improves your quality of life. Efavirenz belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Efavirenz is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, do all of the following: (1) continue to take all HIV medications exactly as prescribed by your doctor, (2) always use an effective barrier method (latex or polyurethane condoms /dental dams) during all sexual activity, and (3) do not share personal items (such as needles/syringes, toothbrushes. and razors) that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This product may also be used to lessen the risk of HIV infection after contact with the virus (for example, due to a needle stick). Ask your doctor for more details.

How to use efavirenz

Read the Patient Information Leaflet if available from your pharmacist before you start taking efavirenz and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.

Take this medication by mouth on an empty stomach. without food, usually once daily at bedtime or as directed by your doctor. Taking efavirenz with food increases the blood level of this medication, which may increase your risk of certain side effects. See Side Effects section.

Swallow this medication whole with water. If you have difficulty swallowing the capsule, it may be opened and the contents mixed gently in a small amount (1 to 2 teaspoons) of soft food such as applesauce, grape jelly, or yogurt. After taking the mixed medication, add 2 more teaspoons of food to the empty mixing container. Swallow the remaining mixture to make sure that you get the entire dose. Swallow within 30 minutes of mixing. Do not eat any food for 2 hours after taking this medication. For babies who cannot eat solid foods, the contents may be mixed in 2 teaspoons of infant formula and drawn up into an oral syringe to be given to the baby. (See Patient Information Leaflet.)

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). In children, the dosage is also based on weight .

It is very important to continue taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not skip any doses. Do not increase your dose, take this drug more often than prescribed, or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects.

This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.

Side Effects

Dizziness. trouble sleeping. drowsiness, unusual dreams. and trouble concentrating may frequently occur. These side effects may begin 1-2 days after starting this medication and usually go away in 2-4 weeks. They are also reduced by taking efavirenz on an empty stomach at bedtime. Avoid alcohol and street drugs while taking efavirenz. They may worsen these side effects.

If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Some people may experience worsening of a previous medical condition (such as an old infection) as their immune systems improve, or develop new conditions because their immune systems have become overactive. This reaction may occur at any time (soon after starting HIV treatment or many months later). Tell your doctor right away if you have any serious side effects, including: unexplained weight loss. persistent muscle aches/weakness. joint pain. numbness/tingling of the hands/feet/arms/legs, severe tiredness, vision changes, severe/persistent headaches. signs of infection (such as fever, chills, trouble breathing. cough. non-healing skin sores), signs of an overactive thyroid (such as irritability, nervousness, heat intolerance, fast/pounding/irregular heartbeat. bulging eyes. unusual growth in the neck/thyroid known as a goiter ), signs of a certain nerve problem known as Guillain - Barre Syndrome (such as difficulty breathing/swallowing/moving your eyes. drooping face, paralysis, slurred speech).

Infrequently, serious psychiatric symptoms may occur during efavirenz treatment, although it is unclear if they are caused by efavirenz. These effects may be seen especially in people who have mental/mood conditions. Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (such as depression. rare thoughts of suicide. nervousness, angry behavior, hallucinations ).

Tell your doctor right away if any of these rare but serious side effects occur: signs of liver problems (such as persistent nausea/vomiting, stomach/abdominal pain. severe tiredness, yellowing eyes /skin, dark urine).

Changes in body fat may occur while you are taking this medication (such as increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of treatment with your doctor, as well as the possible use of exercise to reduce this side effect.

Efavirenz can commonly cause a rash that is usually not serious. In adults, a rash may occur in the first 2 weeks after starting treatment and if it is not serious, it will usually resolve in 4 weeks. In children, a rash may occur in the first 4 weeks after starting treatment. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, seek immediate medical attention if you develop any rash.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, blisters, peeling skin, fever, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking efavirenz, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: mental/mood conditions (such as depression, thoughts of suicide, psychosis), liver problems (such as hepatitis B or C, cirrhosis), drug/substance/alcohol abuse, seizures, high cholesterol/triglyceride levels.

This drug may make you dizzy or drowsy or cause trouble concentrating. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

A rash may be more common and serious in children taking efavirenz. Report any rash right away. The doctor may prescribe an antihistamine for your child to take before efavirenz is started. Consult the doctor for more information.

This medication is not recommended for use during pregnancy. It may harm an unborn baby, especially if taken during the first 3 months of pregnancy. Women of childbearing age should have a pregnancy test before starting efavirenz. It is important to prevent pregnancy while taking this medication and for 3 months after treatment. Consult your doctor about using at least 2 reliable forms of birth control (such as condoms with birth control pills) during treatment and for 3 months after the end of treatment (see also Drug Interactions section). If you become pregnant or think you may be pregnant, tell your doctor right away. Discuss the risks and benefits of HIV treatment and alternatives to efavirenz during pregnancy to decrease the risk of HIV transmission to the baby.

This medication passes into breast milk. Because breast milk can transmit HIV, do not breast-feed.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: a certain combination product used to treat chronic hepatitic C (ombitasvir/paritaprevir/ritonavir/dasabuvir).

Do not take this medication with other products that contain efavirenz unless specifically directed by your doctor.

Other medications can affect the removal of efavirenz from your body, which may affect how efavirenz works. Examples include some drugs used to treat seizures (such as carbamazepine, phenobarbital, phenytoin), rifamycins (such as rifampin), among others.

Efavirenz can speed up the removal of many other medications from your body, which may affect how they work. Examples of affected drugs include atovaquone/proguanil, azole antifungals (such as itraconazole, ketoconazole), bedaquiline, calcium channel blockers (such as diltiazem, verapamil), cobicistat, macrolide antibiotics (such as clarithromycin), methadone, rifabutin, sertraline, some cholesterol-lowering statins (such as atorvastatin, pravastatin, simvastatin), certain protease inhibitors (boceprevir, simeprevir), warfarin, among others.

Some other drugs to treat HIV infection (such as elvitegravir, other NNRTIs including etravirine/nevirapine/rilpivirine) may also interact with efavirenz. If you are taking atazanavir with this medication, you may need to also take another medication (ritonavir). Consult your doctor or pharmacist for more details.

This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Talk to your doctor about additional or alternative reliable forms of birth control, and always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity to decrease the risk of spreading HIV to others. Tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your hormonal birth control is not working well. (See also Precautions section.)

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain laboratory tests (including urine cannabinoid tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Laboratory and/or medical tests (such as liver tests, viral load, T-cell counts, cholesterol and triglyceride levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Keep all medical and laboratory appointments.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised May 2016. Copyright(c) 2016 First Databank, Inc.

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Tetralisal, Tetralisal

Lymecycline

Click for further information on drug naming conventions and International Nonproprietary Names .

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.



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Fluconazole Side Effects In Detail, Flucanol

Fluconazole Side Effects

Applies to fluconazole: oral capsule, oral powder for suspension, oral tablet

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by fluconazole. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking fluconazole:

Rare

Abdominal or stomach pain

chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with swallowing

dizziness

fast heartbeat

fever

general feeling of tiredness or weakness

headache

hives, itching, or skin rash

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

nausea and vomiting

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

stomach pain, continuing

tightness in the chest

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting of blood

yellow eyes and skin

Incidence not known:

Black, tarry stools

blistering, peeling, or loosening of the skin

chest pain or discomfort

convulsions

decreased urine

dry mouth

fainting

hoarseness

increased thirst

irregular or slow heart rate

joint or muscle pain

loss of bladder control

lower back or side pain

mood changes

muscle pain or cramps

muscle spasm or jerking of all extremities

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pale skin

red skin lesions, often with a purple center

red, irritated eyes

sore throat

sores, ulcers, or white spots in the mouth or on the lips

sudden loss of consciousness

swollen glands

unusual bleeding or bruising

If any of the following symptoms of overdose occur while taking fluconazole, get emergency help immediately:

Symptoms of overdose:

Fearfulness, suspiciousness, or other mental changes

seeing, hearing, or feeling things that are not there

Minor Side Effects

Some of the side effects that can occur with fluconazole may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Acid or sour stomach

belching

change in taste or bad, unusual, or unpleasant (after) taste

heartburn

indigestion

stomach discomfort or upset

Incidence not known:

Hair loss or thinning of the hair

For Healthcare Professionals

Applies to fluconazole: intravenous solution, oral powder for reconstitution, oral tablet

General

This drug was generally well tolerated. Changes in renal and hematological function test results and hepatic abnormalities reported during therapy with this and comparative agents in some patients, primarily those with serious underlying diseases (e. g. AIDS, cancer); clinical significance and relationship to therapy unclear.

During clinical trials of single-dose therapy, side effects possibly related to therapy were reported in 26% of patients using this drug and 16% of patients using active comparative agents. The most common side effects reported in patients receiving a single 150 mg dose of this drug for vaginitis were headache, nausea, and abdominal pain. Most side effects were of mild to moderate severity.

During clinical trials of multiple-dose therapy, side effects were reported in 16% of patients. Therapy discontinuation occurred in 1.5% and 1.3% of patients due to adverse clinical events and laboratory test abnormalities, respectively. Clinical side effects were reported more often in HIV-infected patients than in non-HIV-infected patients (21% versus 13%), but the patterns in both groups were similar. [Ref ]

Nervous system

Rare cases of seizures have been reported, but a causal relationship was difficult to establish, since some of these patients had cryptococcal meningitis or severe underlying disease. Nonetheless, at least 1 case of seizure following a 100 mg oral dose has been reported.

Seizures, dizziness, paresthesia, somnolence, tremor, and vertigo have also been reported during postmarketing experience. [Ref ]

Very common (10% or more): Headache (up to 13%) Uncommon (0.1% to 1%): Seizures, dizziness, paresthesia, somnolence, vertigo, visual field defect, taste perversion, hyperkinesia, hypertonia Rare (less than 0.1%): Tremor Frequency not reported: Dysesthesias [Ref ]

Gastrointestinal

Very common (10% or more): Nausea, abdominal pain, diarrhea, vomiting Common (1% to 10%): Dyspepsia Uncommon (0.1% to 1%): Constipation, flatulence, loose stools, dry mouth Frequency not reported: General abdominal discomfort [Ref ]

Dry mouth, dyspepsia, and vomiting have also been reported during postmarketing experience. [Ref ]

Hepatic

Fatal hepatic reactions have occurred primarily in patients with serious underlying medical conditions (primarily AIDS or malignancy) and often taking multiple concomitant medications. One reported patient with AIDS experienced acute hepatic necrosis and hepatic failure about 3 weeks after starting this drug.

Transient hepatic reactions have been reported in patients with no other identifiable risk factors. Liver function returned to baseline after stopping this drug.

Serum transaminase elevations (greater than 8 times the upper limit of normal [8 x ULN]; about 1%) and statistically significant increases in AST have been reported. Serum transaminase elevations have been reported primarily in patients with serious underlying medical conditions (primarily AIDS or malignancy) and often taking multiple concomitant medications, including agents known to be hepatotoxic.

Transaminase elevations greater than 2 to 3 x ULN have also been reported.

Cholestasis, hepatocellular damage, and hepatocellular necrosis have also been reported during postmarketing experience. [Ref ]

Very common (10% or more): Increased ALT, increased AST Uncommon (0.1% to 1%): Serum transaminase elevations, cholestasis, jaundice, increased bilirubin Rare (less than 0.1%): Serious hepatic reactions, hepatic toxicity (including fatalities), hepatic failure, hepatocellular necrosis, hepatitis, hepatocellular damage Frequency not reported: Hepatic reactions (ranging from mild transient transaminase elevations to clinical hepatitis, fulminant hepatic failure [including fatalities]), transient hepatic reactions (including hepatitis, jaundice), elevated liver function tests (transient and asymptomatic), cholestatic jaundice, fatal hepatic necrosis, increased plasma levels of hepatic enzymes [Ref ]

Dermatologic

Reversible alopecia has been associated with long-term (2 months or longer) therapy.

In patients with serious underlying diseases (primarily AIDS and malignancy), exfoliative skin disorders have resulted in a fatal outcome.

Acute generalized exanthematous pustulosis, drug eruption, increased sweating, exfoliative skin disorders (including Stevens-Johnson syndrome, toxic epidermal necrolysis), and alopecia have also been reported during postmarketing experience. [Ref ]

Very common (10% or more): Rash Common (1% to 10%): Maculopapular erythema Uncommon (0.1% to 1%): Pruritus, genital pruritus, erythematous rash, dry skin, abnormal skin odor, urticaria, herpes simplex, drug eruption, increased sweating Rare (less than 0.1%): Angioedema, exfoliative skin disorders (including Stevens-Johnson syndrome, toxic epidermal necrolysis), alopecia, acute generalized exanthematous pustulosis, exfoliative dermatitis Frequency not reported: Reversible alopecia, exfoliative skin disorders (including fatalities) [Ref ]

Metabolic

Very common (10% or more): Increased blood alkaline phosphatase Uncommon (0.1% to 1%): Hypokalemia, anorexia, decreased appetite Rare (less than 0.1%): Hypercholesterolemia, hypertriglyceridemia [Ref ]

Hypercholesterolemia, hypertriglyceridemia, and hypokalemia have also been reported during postmarketing experience. [Ref ]

Hypersensitivity

Rare cases of exfoliative dermatitis and ulcerative eruptions consistent with Stevens-Johnson syndrome have been reported in association with hypersensitivity reactions.

A 52-year-old female experienced a fixed drug eruption (FDE) when administered a single 400 mg oral dose for extensive pityriasis versicolor. Within 12 hours, she noticed 3 oval, painful, eroded, pigmented patches over her trunk with diameters of 3 to 4 cm and erythematous halos. A clinical diagnosis of FDE due to drug therapy was made. The FDE was confirmed when the patient was rechallenged with a 25 mg oral dose. [Ref ]

Rare (less than 0.1%): Anaphylactic reaction, anaphylaxis Frequency not reported: Hypersensitivity reactions (including generalized edema, stridor, hypotension, exfoliative dermatitis, ulcerative eruptions), fixed drug eruption Postmarketing reports: Anaphylaxis (including angioedema, face edema, pruritus) [Ref ]

Cardiovascular

Most reports of QT interval prolongation and torsades de pointes involved seriously ill patients with multiple confounding risk factors, such as structural heart disease, electrolyte abnormalities, and concomitant medications that may have been contributory.

An 11-year-old male with neurofibromatosis-1 presented to the hospital in septic shock secondary to a perforated gastric volvulus. After initial stabilization, the patient underwent total gastrectomy and multiple peritoneal lavages. Culture of peritoneal fluid showed infection with Candida albicans. Therapy was started with fluconazole 150 mg IV every 12 hours. After starting this drug, the patient developed QT prolongation and complex ventricular arrhythmia. The drug was discontinued. Over the subsequent 36-hours, the patient remained in sinus rhythm except for one brief run of ventricular bigeminy. An ECG recorded 5 months after admission (and about 4 months after cessation of all QT-prolonging medications) showed sinus rhythm with normal heart rate and corrected QT interval.

QT prolongation and torsade de pointes have also been reported during postmarketing experience. [Ref ]

Rare (less than 0.1%): QT prolongation, torsade de pointes Frequency not reported: Prolongation of the QT interval on the ECG, palpitations, complex ventricular arrhythmia [Ref ]

Hematologic

Anemia, eosinophilia, leukopenia, neutropenia, and thrombocytopenia have been reported, often in patients with severe deep fungal infections or underlying disease.

Spontaneous reports of anemia were more frequent in patients 65 years of age or older than in those between 12 and 65 years of age; however, there is a natural increase in the incidence of anemia in the elderly. A causal relationship to drug exposure could not be determined.

Anemia, leukopenia, neutropenia, agranulocytosis, and thrombocytopenia have also been reported during postmarketing experience. [Ref ]

Uncommon (0.1% to 1%): Anemia Rare (less than 0.1%): Leukopenia, neutropenia, agranulocytosis, thrombocytopenia Frequency not reported: Eosinophilia [Ref ]

Other

Uncommon (0.1% to 1%): Thirst, fatigue, malaise, pain, rigors, asthenia, fever, flushing, hot flushes Rare (less than 0.1%): Face edema Frequency not reported: Infection due to resistant microorganisms [Ref ]

Fever, asthenia, fatigue, and malaise have also been reported during postmarketing experience. [Ref ]

Musculoskeletal

Uncommon (0.1% to 1%): Back pain, myalgia Frequency not reported: Joint pain, finger stiffness [Ref ]

Myalgia has also been reported during postmarketing experience. [Ref ]

Psychiatric

Uncommon (0.1% to 1%): Insomnia, nervousness

Insomnia has also been reported during postmarketing experience.

Renal

Uncommon (0.1% to 1%): Polyuria, renal pain, changes in renal function tests Frequency not reported: Membranous nephropathy Postmarketing reports: Acute renal failure [Ref ]

A 58-year-old female with a history of hypertension and cervical cancer experienced membranous nephropathy coincident with this drug. The patient presented with increasing generalized edema accompanied by nausea and indigestion for 3 weeks. Clinical findings showed the patient had stage I membranous nephropathy. At initial presentation, the patient's medication history included amlodipine, hydrochlorothiazide, metoclopramide, and levosulpiride. She did not admit to taking fluconazole. Five months after the initial presentation, the patient returned with reports of increasing pedal edema. At that point, the patient admitted to taking this drug once a week for tinea pedis. The patient went into complete remission when the drug was stopped.

Spontaneous reports of acute renal failure were more frequent in patients 65 years of age or older than in those between 12 and 65 years of age; however, there is a natural increase in the incidence of renal failure in the elderly. A causal relationship to drug exposure could not be determined. [Ref ]

Genitourinary

Uncommon (0.1% to 1%): Intermenstrual bleeding, dysmenorrhea, leukorrhea, menorrhagia, uterine spasm, vaginal disorders, female sexual dysfunction

Respiratory

Uncommon (0.1% to 1%): Pharyngitis Frequency not reported: Respiratory disorders [Ref ]

Ocular

Uncommon (0.1% to 1%): Abnormal vision

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Grant SM, Clissold SP "Fluconazole: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial and systemic mycoses." Drugs 39 (1990): 877-916

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Diflucan (fluconazole)." Roerig Division, New York, NY.

5. Saag MS, Powderly WG, Cloud GA, et al "Comparison of amphotericin B with fluconazole in the treatment of acute AIDS-associated cryptococcal meningitis." N Engl J Med 326 (1992): 83-9

6. Inman W, Pearce G, Wilton L "Safety of fluconazole in the treatment of vaginal candidiasis - a prescription-event monitoring study, with special reference to the outcome of pregnancy." Eur J Clin Pharmacol 46 (1994): 115-8

7. Phillips RJ, Watson SA, McKay FF "An open multicentre study of the efficacy and safety of a single dose of fluconazole 150 mg in the treatment of vaginal candidiasis in general practice." Br J Clin Pract 44 (1990): 219-22

8. Gupta AK, Ryder JE "The use of oral antifungal agents to treat onychomycosis." Dermatol Clin 21 (2003): 469-79, vi

9. Thompson GR 3rd, Cadena J, Patterson TF "Overview of antifungal agents." Clin Chest Med 30 (2009): 203-15, v

10. Robinson PA, Knirsch AK, Joseph JA "Fluconazole for life-threatening fungal infections in patients who cannot be treated with conventional antifungal agents." Rev Infect Dis 12 (1990): s349-63

11. Bozzette SA, Larsen RA, Chiu J, et al "A placebo-controlled trial of maintenance therapy with fluconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome." N Engl J Med 324 (1991): 580-4

12. Holechek MJ "Medication review: fluconazole." ANNA J 18 (1991): 585-6

13. Goodman JL, Winston DJ, Greenfield RA, et al "A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation." N Engl J Med 326 (1992): 845-51

14. Morrow JD "Fluconazole: a new triazole antifungal agent." Am J Med Sci 302 (1991): 129-32

15. Vincent-Ballereau FN, Patey ON, Lafaix C "Fluconazole: review and situation among antifungal drugs in the treatment of opportunistic mycoses of human immuno-deficiency virus infections." Pharm Weekbl Sci 13 (1990): 45-57

16. Ikemoto H "A clinical study of fluconazole for the treatment of deep mycoses." Diagn Microbiol Infect Dis 12 (1989): s239-47

17. De Wit S, Clumeck N "Fluconazole in the treatment of fungal infections associated with AIDS." Infection 17 (1989): 121-3

18. Gearhart MO "Worsening of liver function with fluconazole and review of azole antifungal hepatotoxicity." Ann Pharmacother 28 (1994): 1177-81

19. Wells C, Lever AM "Dose-dependent fluconazole hepatotoxicity proven on biopsy and rechallenge ." J Infect 24 (1992): 111-2

20. Munoz P, Moreno S, Berenguer J, et al "Fluconazole-related hepatotoxicity in patients with acquired immunodeficiency syndrome." Arch Intern Med 151 (1991): 1020-1

21. Franklin IM, Elias E, Hirsch C "Fluconazole-induced jaundice." Lancet 336 (1990): 565

22. Jacobson MA, Hanks DK, Ferrell LD "Fatal acute hepatic necrosis due to fluconazole." Am J Med 96 (1994): 188-90

23. Nightingale SD, Cal SX, Peterson DM, et al "Primary prophylaxis with fluconazole against systemic fungal infections in HIV-positive patients." AIDS 6 (1992): 191-4

24. Guillaume MP, Deprez C, Cogan E "Subacute mitochondrial liver disease in a patient with AIDS: possible relationship to prolonged fluconazole administration." Am J Gastroenterol 91 (1996): 165-8

25. Craig TJ, Peralta F, Boggavarapu J "Desensitization for fluconazole hypersensitivity." J Allergy Clin Immunol 98 (1996): 845-6

26. Shear NH "Alopecia associated with fluconazole therapy." Ann Intern Med 125 (1996): 153

27. Pappas PG, Kauffman CA, Perfect J, Johnson PC, Mckinsey DS, Bamberger DM, Hamill R, Sharkey PK, Chapman SW, Sobel JD "Alopecia associated with fluconazole therapy." Ann Intern Med 123 (1995): 354-7

28. Goldsmith LA "Alopecia associated with fluconazole therapy." Ann Intern Med 125 (1996): 153

29. Neuhaus G, Pavic N, Pletscher M "Anaphylactic reaction after oral fluconazole." Br Med J 302 (1991): 1341

30. Gupta R, Thami GP "Fixed drug eruption caused by itraconazole: Reactivity and cross reactivity." J Am Acad Dermatol 58 (2008): 521-522

31. Gussenhoven MJ, Haak A, Peereboom-Wynia JD, van Wout JW "Stevens-Johnson syndrome after fluconazole." Lancet 338 (1991): 120

32. Abbott M, Hughes DL, Patel R, Kinghorn GR "Angio-oedema after fluconazole." Lancet 338 (1991): 633

33. Beecker J, Colantonio S "Fixed drug eruption due to fluconazole." CMAJ 184 (2012): 675

34. McMahon JH, Grayson ML "Torsades de pointes in a patient receiving fluconazole for cerebral cryptococcosis." Am J Health Syst Pharm 65 (2008): 619-23

35. Esch JJ, Kantoch MJ "Torsades de pointes ventricular tachycardia in a pediatric patient treated with fluconazole." Pediatr Cardiol 29 (2007): 210-3

36. Mercurio MG, Elewski BE "Thrombocytopenia caused by fluconazole - reply." J Am Acad Dermatol 35 (1996): 284

37. Kalivas J "Thrombocytopenia caused by fluconazole." J Am Acad Dermatol 35 (1996): 284

38. Pappas PG, Kauffman CA, Sobel JD "Alopecia associated with fluconazole therapy." Ann Intern Med 125 (1996): 153-4

39. Mercurio MG, Elewski BE "Thrombocytopenia caused by fluconazole therapy." J Am Acad Dermatol 32 (1995): 525-6

40. Agarwal A, Sakhuja V, Chugh KS "Fluconazole-induced thrombocytopenia." Ann Intern Med 113 (1990): 899

41. Shin GT, Yim H, Park J, Kim H "Membranous nephropathy associated with fluconazole treatment." Am J Kidney Dis 49 (2007): 318-22

Not all side effects for fluconazole may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .



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Keflex Side Effects In Detail, Kefalex

Keflex Side Effects

For the Consumer

Applies to cephalexin: oral capsule, oral powder for suspension, oral tablet, oral tablet for suspension

In addition to its needed effects, some unwanted effects may be caused by cephalexin (the active ingredient contained in Keflex). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking cephalexin:

More common:

Diarrhea

Rare

Abdominal or stomach pain

blistering, peeling, or loosening of the skin

chills

clay-colored stools

cough

dark urine

diarrhea

dizziness

fever

general tiredness and weakness

headache

itching

joint or muscle pain

light-colored stools

loss of appetite

nausea and vomiting

rash

red skin lesions, often with a purple center

red, irritated eyes

sore throat

sores, ulcers, or white spots in the mouth or on the lips

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting of blood

yellow eyes or skin

Incidence not known:

Abdominal or stomach cramps or tenderness

back or leg pains

black, tarry stools

bleeding gums

bloating

blood in the urine or stools

chest pain

coughing up blood

diarrhea, watery and severe, which may also be bloody

difficulty with breathing or swallowing

fast heartbeat

general body swelling

hives

increased menstrual flow or vaginal bleeding

increased thirst

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

nosebleeds

pain

painful or difficult urination

pale skin

paralysis

pinpoint red spots on the skin

prolonged bleeding from cuts

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red or black, tarry stools

red or dark brown urine

shortness of breath

swollen or painful glands

tightness in the chest

unusual bleeding or bruising

unusual weight loss

watery or bloody diarrhea

wheezing

Minor Side Effects

Some of the side effects that can occur with cephalexin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:

Acid or sour stomach

anxiety

belching

burning feeling in the chest or stomach

difficulty with moving

dry mouth

heartburn

hives or welts

hyperventilation

indigestion

irregular heartbeats

irritability

itching of the vagina or genital area

muscle pain or stiffness

nervousness

pain during sexual intercourse

pain, swelling, or redness in the joints

redness of the skin

restlessness

seeing, hearing, or feeling things that are not there

shaking

stomach upset

trouble with sleeping

white or brownish vaginal discharge

For Healthcare Professionals

Applies to cephalexin: oral capsule, oral powder for reconstitution, oral tablet, oral tablet dispersible

General

Cephalexin is generally well-tolerated. Large studies report an overall 6% incidence of side effects, some of which may not be related to cephalexin (the active ingredient contained in Keflex) [Ref ]

Hypersensitivity

Hypersensitivity side effects have included fever, urticaria, rash, eosinophilia, anaphylaxis, angioedema, contact dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute paronychia, and hepatitis. [Ref ]

Up to 20% of patients with a penicillin allergy may be allergic to cephalexin. [Ref ]

Gastrointestinal

Gastrointestinal side effects have included diarrhea, nausea, vomiting, dyspepsia, abdominal cramping, anorexia, and anal pruritus. Diarrhea due to Clostridium difficile colitis has been reported with some cephalosporins. [Ref ]

If diarrhea occurs and it does not resolve with discontinuation of the drug and/or institution of standard antidiarrheal therapy, pseudomembranous colitis should be suspected. [Ref ]

Hepatic

Hepatic side effects have included transient elevations of liver function tests, transient hepatitis, and rare cases of cholestatic jaundice. [Ref ]

Renal

Renal side effects have rarely included interstitial nephritis. Reversible fever, azotemia, pyuria and eosinophiluria are the hallmarks of cephalosporin-induced interstitial nephritis. Acute tubular necrosis has also been reported. [Ref ]

Hematologic

Hematologic side effects have included eosinophilia, neutropenia, thrombocytopenia and hemolytic anemia. [Ref ]

Nervous system

Nervous system side effects have included dizziness, fatigue, headache, agitation, confusion, and hallucinations. Reversible ototoxicity and vertigo, apparently due to labyrinthine disease, have been reported in a few patients with renal disease. [Ref ]

Genitourinary

Genitourinary side effects have included genital pruritus, genital moniliasis, vaginitis, and vaginal discharge. [Ref ]

Musculoskeletal

Musculoskeletal side effects have included arthralgia, arthritis, and joint disorder. [Ref ]

Dermatologic

Dermatologic side effects have included urticaria, rash, contact dermatitis, erythema multiforme, and toxic epidermal necrolysis. Acute generalized exanthematous pustulosis has been reported. [Ref ]

References

1. "Product Information. Keflex (cephalexin)." Dista Products Company, Indianapolis, IN.

2. Burt RA "A review of the drug events reported by 12,917 patients treated with cephalexin." Postgrad Med J 59 (1983): 47-50,51-3

3. Filipe P, Almeida RSLS, Rodrigo FG "Occupational allergic contact dermatitis from cephalosporins." Contact Dermatitis 34 (1996): 226

4. Moellering RC Jr, Swartz MN "The newer cephalosporins." N Engl J Med 294 (1976): 24-8

5. Milligan A, Douglas WS "Contact dermatitis to cephalexin." Contact Dermatitis 15 (1986): 91

6. Jackson H, Vion B, Levy PM "Generalized eruptive pustular drug rash due to cephalexin." Dermatology 177 (1988): 292-4

7. Dave J, Heathcock R, Fenelon L, et al "Cephalexin induced toxic epidermal necrolysis." J Antimicrob Chemother 28 (1991): 477-8

8. Baran R, Perrin C "Fixed-drug eruption presenting as an acute paronychia." Br J Dermatol 125 (1991): 592-5

9. Hogan DJ, Rooney ME "Toxic epidermal necrolysis due to cephalexin." J Am Acad Dermatol 17 (1987): 852-3

10. Harnar TJ, Dobke M, Simoni J, Ninnemann JL "Toxic epidermal necrolysis complicated by severe wound sepsis: a case study." J Burn Care Rehabil 8 (1987): 554-7

11. Raff MJ "Cephalexin in lower respiratory tract infections." Postgrad Med J 59 (1983): 32-9

12. Manoharan A, Kot T "Cephalexin-induced haemolytic anaemia." Med J Aust 147 (1987): 202

13. Ammann R, Neftel K, Hardmeier T, Reinhardt M "Cephalosporin-induced cholestatic jaundice." Lancet 2 (1982): 336-7

14. Ramakrishnan K, Scheid DC "Diagnosis and management of acute pyelonephritis in adults." Am Fam Physician 71 (2005): 933-42

15. Longstreth KL, Robbins SD, Smavatkul C, Doe NS "Cephalexin-induced acute tubular necrosis." Pharmacotherapy 24 (2004): 808-11

16. Sennesael J, Verbeelen D, Lauwers S "Ototoxicity associated with cephalexin in two patients with renal failure." Lancet 2 (1982): 1154-5

17. Wolf R, Dechner E, Ophir J, Brenner S "Cephalexin: a nonthiol drug that may induced pemphigus vulgaris." Int J Dermatol 30 (1991): 213-5

18. Holscher CM, Mauck SK, Armstrong L, Buchanan JA "Man with rash and nausea. Acute generalized exanthematous pustulosis after cephalexin use." Ann Emerg Med 58 (2011): 508, 516

Not all side effects for Keflex may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .

More about Keflex (cephalexin)

Consumer resources

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill. knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Drug Status



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Zimox, Zimox

amoxicillin

amoxicillin

an antibiotic that is a penicillin analogue similar in action to ampicillin but more efficiently absorbed from the gastrointestinal tract and therefore requiring less frequent dosage and not as likely to cause diarrhea.

a·mox·i·cil·lin

A semisynthetic penicillin antibiotic with an antimicrobial spectrum similar to that of ampicillin.

amoxicillin

/amox·i·cil·lin/ ( ah-mok″sĭ-sil?in ) a semisynthetic derivative of ampicillin effective against a broad spectrum of gram-positive and gram-negative bacteria.

amoxicillin

A semisynthetic penicillin, C 16 H 19 N 3 O 5 S, having an antibacterial spectrum of action similar to that of ampicillin.

amoxicillin

a beta-lactam semisynthetic oral penicillin antibiotic.

indication It is prescribed in the treatment of infections caused by a susceptible gram-negative or gram-positive bacteria.

contraindication Known hypersensitivity to any penicillin prohibits its use.

adverse effects Among the most serious adverse reactions are anaphylaxis, nausea, and diarrhea. Allergic reactions and rashes are common.

amoxicillin

Infectious disease A broad-spectrum semisynthetic penicillin with activity similar to that of ampicillin

amoxicillin

Amoxycillin, an AMPICILLIN - like penicillin antibiotic, effective in TYPHOID and many other infections. Brand names are Amoxil and Galenamox. Compounded with lansoprazol and clarithromycin it is marketed as Heliclear.

amoxicillin

penicillin antibiotic of similar action to ampicillin; usually administered as 250 mg by mouth every 8 hours (125 mg every 8 hours for a child) for soft-tissue infections

a·mox·i·cil·lin

A semisynthetic penicillin antibiotic with an antimicrobial spectrum similar to that of ampicillin.

amoxicillin, amoxycillin

an aminopenicillin, similar in action to ampicillin and susceptible to β-lactamase, but more efficiently absorbed from the gastrointestinal tract and with a longer duration of action.

addition of clavulanic acid widens the spectrum of activity and renders amoxicillin resistant to β-lactamase. A widely used antibiotic in dogs and cats.

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