Finimal Painkiller Bayer, Finimal

Finimal means end to the pain.

Headache, muscle aches, menstrual pain.

From toothache, neuralgia, lumbago.

Pain with flu and colds.

Lowering fever with flu and colds.

Pain after vaccination.

Fever-lowering with vaccinations.

Contains 500 mg acetaminophen and 50 mg of caffeine per tablet.

Acetaminophen relieves pain and lower fever. Caffeine enhances the possible analgesic effect of paracetamol and is uplifting. No stomach and intestinal complaints.

Finimal belongs to painkillers that cause stomach and intestinal problems.

Leaflet of Finimal painkiller Bayer

Contains 500 mg acetaminophen and 50 mg of caffeine per tablet.

Adults and teenagers from 15 years: 1-2 tablets at a time, up to 6 tablets per day. Teens 12-15 years: 1 tablet at a time, up to 4-6 times per day. Children 9-12 years: 1 tablet each time, 3-4 times per day. Children aged 6-9 years: 1/2 tablet at a time up to 4-6 times per day. Teens aged 12 and older: between two intakes must be at least 4 hours.

Caution! Do not use in hypersensitivity to paracetamol.

Parlodel Informaci - N Espa - Ola De La Droga, Parloder

Parlodel

¿Qué es Parlodel?

Esta guía del medicamento provee información sobre bromocriptine de la marca Parlodel. Cycloset es el nombre de otra marca de bromocriptine que no ha sido incluida en esta guía del medicamento.

La marca de bromocriptine Parlodel es usada para tratar ciertas condiciones causadas por un desequilibrio de hormonas en el que hay demasiada prolactina en la sangre (hiperprolactinemia). Los síntomas incluyen falta de desarrollo sexual en los adolescentes. Las mujeres pueden tener periodos menstruales ausentes, pérdida de interés en las relaciones sexuales, calores menopáusicos, infertilidad, o producción inesperada y fuga de leche materna de los pezones. Los hombres pueden tener mamas agrandadas, libido disminuida, vellos faciales o corporales reducidos, y pérdida de músculo. Parlodel es también usado para tratar estos trastornos cuando son causados por tumores del cerebro que pueden producir prolactina.

Parlodel es algunas veces usado junto con cirugía o radiación para tratar acromegalia, una condición causada por un tumor de la glándula pituitaria que produce demasiada hormona de crecimiento. Parlodel es también usado para tratar síntomas de la enfermedad de Parkinson, como rigidez, temblores, espasmos musculares, y pobre control de los músculos.

Bromocriptine puede también usarse para fines no mencionados en esta guía del medicamento.

¿Cuál es la información más importante que debo saber sobre Parlodel?

Esta guía del medicamento provee información sobre bromocriptine de la marca Parlodel. Cycloset es el nombre de otra marca de bromocriptine que no ha sido incluida en esta guía del medicamento.

Usted no debe usar Parlodel si usted tiene presión arterial alta (hipertensión) no controlada, si ha tenido recientemente un bebé y si usted tiene un historial de enfermedad de las arterias coronarias o enfermedad cardíaca grave, o si tiene hipertensión causada por el embarazo (incluyendo eclampsia y pre-eclampsia). Quizás necesite dejar de tomar Parlodel si usted queda embarazada durante el tratamiento. Siga las instrucciones de su médico.

Usted no debe amamantar mientras está usando bromocriptine.

Dígale de inmediato a su médico si queda embarazada mientras toma bromocriptine.

¿Qué debería discutir con el profesional del cuidado de la salud antes de tomar Parlodel?

Usted no debe usar este medicamento si usted es alérgico a bromocriptine o a una medicina de cornezuelo del centeno (Ergomar, Cafergot, Migergot, D. H.E. 45, Migranal, Methergine).

Usted no debe usar Parlodel si usted tiene:

presión arterial alta (hipertensión) no controlada;

hipertensión causada por el embarazo (incluyendo eclampsia y pre-eclampsia);

si usted también está usando una medicina derivada de cornezuelo del centeno (ergot) para el tratamiento de los dolores de cabeza por migraña; o

si ha tenido recientemente un bebé y si usted tiene un historial de enfermedad de las arterias coronarias o enfermedad cardíaca grave.

Bromocriptine puede contener lactosa. Antes de tomar Parlodel, dígale a su médico si usted tiene una forma hereditaria de intolerancia a la galactosa, deficiencia severa de lactasa, o malabsorción de glucosa-galactosa.

Para asegurarse que usted puede tomar bromocriptine de forma segura, dígale a su médico si usted tiene cualquiera de estas otras condiciones:

presión arterial alta o baja, enfermedad del corazón, o un historial de ataque al corazón;

enfermedad del hígado o riñón;

un tumor de la glándula pituitaria;

una úlcera gástrica o historial de sangrado en el estómago o del intestino; o

un historial de enfermedad mental o psicosis.

Categoría B del embarazo por la FDA. No se espera que bromocriptine le cause daño al bebé nonato. Sin embargo, un tumor de la glándula pituitaria en la madre puede expandirse durante el embarazo. La presión arterial alta también puede ocurrir durante el embarazo y bromocriptine puede ser peligroso si es tomado por una mujer embarazada con presión arterial alta. Dígale a su médico si usted está embarazada o planea quedar embarazada durante el tratamiento.

Algunas mujeres toman Parlodel para normalizar los periodos menstruales y aumentar las oportunidades de quedar embarazada. Dígale a su médico tan pronto quede embarazada. Usted probablemente necesitará dejar de tomar Parlodel Siga las instrucciones de su médico.

Si usted no está tomando Parlodel para ayudarle a quedar embarazada, use un método no-hormonal para el control de la natalidad (como un condón, diafragma, o espermicida) para prevenir el embarazo durante el tratamiento. Su médico también puede querer hacerle una prueba de embarazo cada 4 semanas durante el tratamiento.

Bromocriptine disminuye la hormona necesaria para producir leche materna. No tome este medicamento se está amamantando a un bebé.

¿Cómo debo tomar Parlodel?

Tómelo exactamente como lo haya recetado su médico. No lo tome en cantidades mayores o menores, o por más tiempo de lo recomendado. Siga las instrucciones en la etiqueta de su prescripción. Tal vez su médico en ocasiones cambie su dosis para asegurarse de que está obteniendo los mejores resultados.

Parlodel por lo general se toma dos veces al día con comida.

Mientras usa bromocriptine, usted puede necesitar exámenes de sangre en la oficina de su médico. Visite a su médico con regularidad.

Usted puede tener un incremento en el impulso por el deseo sexual, impulso inusual por apostar, u otros impulsos intensos mientras toma esta medicina. Hable con su médico si usted cree tener impulsos intensos o inusuales mientras está tomando Parlodel .

Algunas personas que toman medicamentos para la enfermedad de Parkinson han desarrollado cáncer de la piel (melanoma). Sin embargo, las personas con la enfermedad de Parkinson pueden tener un riesgo más alto de melanoma. Hable con su médico acerca de este riesgo y los síntomas de la piel que debe observar. Usted puede necesitar exámenes regulares de la piel.

Guarde a temperatura ambiente fuera de la humedad, el calor, y la luz.

¿Qué sucede si me salto una dosis?

Tome la dosis de Parlodel pasada con comida tan pronto se acuerde. Sáltese la dosis pasada si ya casi es hora para la siguiente dosis. No tome más medicina para alcanzar la dosis pasada.

¿Qué sucedería en una sobredosis?

Busque atención médica de emergencia o llame a la línea de Poison Help al 1-800-222-1222. Los síntomas de sobredosis pueden incluir náusea, vómitos, estreñimiento, sudoración, piel pálida, mareos, somnolencia, bostezo, confusión, alucinaciones, y desmayo.

¿Qué debo evitar mientras tomo Parlodel?

Evite usar una medicina derivada de cornezuelo del centeno en tiempo mientras usted está tomando Parlodel. medicinas derivadas de cornezuelo del centeno (ergot) se usan para el tratamiento de los dolores de cabeza por migraña, y incluyen ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D. H.E. 45, Migranal), y methylergonovine (Methergine):

Bromocriptine puede perjudicar su pensamiento o reacciones. Algunas personas que toman Parlodel se han quedado dormidas durante las actividades normales del día, como durante el trabajo, hablar, comer, o conducir un vehículo. Usted puede quedarse dormido de forma súbita, aun después de sentirse despierto. Tenga cuidado si usted conduce un vehículo o tiene que hacer algo que demande se mantenga alerta.

¿Cuáles son los efectos secundarios posibles de Parlodel?

Busque atención médica de emergencia si usted tiene alguno de estos síntomas de una reacción alérgica: ronchas, dificultad para respirar; hinchazón de la cara, labios, lengua, o garganta.

Deje de usar esta medicina y llame a su médico de inmediato si usted tiene un efecto secundario grave como:

problemas con la visión, nariz mocosa constante;

dolor de pecho, dolor al respirar, latido cardíaco rápido, respiración rápida, siente que le falta aire al respirar (especialmente cuando está acostado);

dolor de espalda, hinchazón en sus tobillos o pies, orinar menos de lo usual o nada en absoluto;

confusión, alucinaciones, sentir que se puede desmayar;

nivel bajo de azúcar en la sangre (dolor de cabeza, hambre, debilidad, sudoración, temblores, irritabilidad, dificultad para concentrarse);

movimientos musculares que usted no puede controlar, pérdida del equilibrio o la coordinación;

heces fecales negras o con sangre, toser sangre o vómito que parece café molido; o

presión arterial peligrosamente alta (dolor de cabeza severo, visión borrosa, zumbido en sus oídos, ansiedad, confusión, dolor de pecho, falta de aire al respirar, latidos cardíacos desiguales, convulsiones).

Efectos secundarios de menor gravedad pueden incluir:

mareos, sensación de girar, somnolencia leve, sentirse cansado;

dolor de cabeza leve, sentirse deprimido, problemas para dormir (insomnio);

boca seca, nariz congestionada;

malestar estomacal, náusea, vómito, dolor de estómago, pérdida del apetito, diarrea, estreñimiento; o

sensación fría o entumecimiento en sus dedos.

Esta lista no menciona todos los efectos secundarios y puede ser que ocurran otros. Llame a su médico para consejos médicos relacionados a efectos secundarios. Usted puede reportar efectos secundarios llamando al FDA al 1-800-FDA-1088.

¿Qué otras drogas afectarán a Parlodel?

Varias drogas pueden tener interacciones con bromocriptine. La lista que se presenta abajo no incluye todas las drogas. Dígale a su médico si usted está usando:

un antidepresivo, un sedante o narcóticos para el dolor, medicinas para el tratamiento de problemas psiquiátricos;

un antibiótico o medicamento antifúngico, drogas contra la malaria;

medicamento para asma o alergias;

medicinas para el cáncer, medicina para evitar el rechazo de un trasplante de órgano

medicamentos para reducir el colesterol como simvastatin (Zocor);

un medicamento antidiabético oral;

medicamento para el corazón o la presión arterial, medicamentos para el ritmo cardíaco;

medicamentos para el tratamiento del VIH o SIDA

medicamento para convulsiones;

sildenafil (Viagra) y otras medicinas para la disfunción eréctil; o

medicinas para reducir el ácido del estómago.

Esta lista no incluye todas las drogas y hay muchas otras drogas que pueden tener interacciones con bromocriptine. Dígale a su médico acerca de todos los medicamentos que usted usa. Incluya los productos que se obtienen con o sin receta, vitaminas, y productos herbarios. No empiece un nuevo medicamento sin primero decirle a su médico. Mantenga una lista de todas sus medicinas y muéstresela a cualquier profesional de la salud que lo atienda.

¿Dónde puedo obtener más información?

Su médico o farmacéutico le puede dar más información acerca de bromocriptine (Parlodel).

Recuerde, mantenga ésta y todas las otras medicinas fuera del alcance de los niños, no comparta nunca sus medicinas con otros, y use este medicamento sólo para la condición por la que fue recetada.

Se ha hecho todo lo posible para que la información que proviene de Cerner Multum, Inc. ('Multum') sea precisa, actual, y completa, pero no se hace garantía de tal. La información sobre el medicamento incluida aquí puede tener nuevas recomendaciones. La información preparada por Multum se ha creado para uso del profesional de la salud y para el consumidor en los Estados Unidos de Norteamérica (EE. UU.) y por lo cual Multum no certifica que el uso fuera de los EE. UU. sea apropiado, a menos que se mencione específicamente lo cual. La información de Multum sobre drogas no sanciona drogas, ni diagnóstica al paciente o recomienda terapia. La información de Multum sobre drogas sirve como una fuente de información diseñada para la ayuda del profesional de la salud licenciado en el cuidado de sus pacientes y/o para servir al consumidor que reciba este servicio como un suplemento a, y no como sustituto de la competencia, experiencia, conocimiento y opinión del profesional de la salud. La ausencia en éste de una advertencia para una droga o combinación de drogas no debe, de ninguna forma, interpretarse como que la droga o la combinación de drogas sean seguras, efectivas, o apropiadas para cualquier paciente. Multum no se responsabiliza por ningún aspecto del cuidado médico que reciba con la ayuda de la información que proviene de Multum. La información incluida aquí no se ha creado con la intención de cubrir todos los usos posibles, instrucciones, precauciones, advertencias, interacciones con otras drogas, reacciones alérgicas, o efectos secundarios. Si usted tiene alguna pregunta acerca de las drogas que está tomando, consulte con su médico, enfermera, o farmacéutico.

Copyright 1996-2012 Cerner Multum, Inc. Version: 1.02. Revision Date: 8/25/2014 7:34:39 AM.

Ansiten, Ansiten

Buspirone is an antidepressant used to treat anxiety disorders such as obsessive-compulsive disorder (OCD) and social phobia. It can be also applied in other cases.

Dosage and direction

Take Buspar by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you.

Precautions Before taking Buspirone tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have bipolar confusion, eye, liver or kidney problems. Avoid drinking alcohol as well as eating grapefruit or drinking grapefruit juice while you are being treated with this medication. Aged people can be more sensitive to side effects of the medicine. During the pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.

Buspar should not be used by pregnant/nursing women or children as well as by the patients having demonstrated a reaction of hypersensitivity to Buspirone.

Possible side effect The most common side effects are fever, insomnia, tremor, anxiety, blurred vision, vomiting, diarrhea, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Drug interaction Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use before using this medication. Buspirone can interact with: * Alcohol; * Grapefruit, grapefruit juice, grapefruit extract; * Haloperidol; * Rifampicin. Turn to your doctor or pharmacist for more details.

Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.

Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

Storage Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from children and pets.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Dilcardia 120 Xl, Dilcardia

DILCARDIA 120 XL

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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Drugs. com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Sep 2nd, 2016), Cerner Multum™ (updated Sep 5th, 2016), Wolters Kluwer™ (updated Aug 8th, 2016) and others. To view content sources and attributions, please refer to our editorial policy .

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Amoksiklav - Drug Review Dosage, Side Effects, Action, Buy Amoksiklav, Amoksiklav

Amoksiklav

Amoksiklav belongs to a group of antibiotics called penicillin. When combined with Amoxicillin. Amoksiklav fights bacteria that cause various infections in the body.

Amoksiklav is available under the brand name Augmentin which comes in tablet and liquid forms. It should be taken by patients who are undergoing treatment for various infections such as sinusitis. urinary tract infections. pneumonia. bronchitis. ear infections. and skin infections. It can be taken by adults and even children. Amoksiklav is not effective in treating common infections like the flu or colds.

Adults are usually prescribed 500 milligrams of Amoksiklav every 12 hours, or 250 milligrams every 8 hours. For more severe cases of infections, particularly in the respiratory tract, the dosage can be increased to 875 milligrams every 12 hours, or 500 milligrams every 8 hours.

Those who have weakened renal function are not required to have a reduction in dosage unless their injury is serious. Usually, seriously injured patients are not allowed to take 875 milligrams of Amoksiklav.

Patients suffering from hemodialysis are required to have at least 250 milligrams of Amoksiklav depending on the seriousness of the infection. Patients are required to take additional dosages during and after dialysis. Children who weigh more than 80 lbs should be given dosages similar to those of adults.

Amoksiklav can be administered even if the patient has an empty stomach. However, for best results it is advised that the patient take Amoksiklav prior to a meal. It would also lessen the chances of a gastrointestinal problem.

The tablet form of Augmentin should be taken as a whole. The chewable tablet should be chewed first and never swallowed as a whole. The extended-release tablet should be swallowed whole or broken into halves, but never chewed. The liquid form should be shaken first before taking.

Amoksiklav must be taken at equal intervals as prescribed by your doctor or pharmacist. Taking the medication regularly allows a patient to get the most effectiveness of Amoksiklav.

In case a patient misses a dose, they should take it immediately. If the next dose is almost due, it is recommended that they pass over the missed dosage and then proceed to take the dosage at the next scheduled dosage. It is not recommended that patients take another medicine to make up for a missed dose.

Like most medicines, Amoksiklav can result to side effects, although the chances are pretty low. Some of the less serious side effects include difficulty in breathing, hives. and skin edema of the face, lips. and throat. More serious side effects may include fever. stomach pain, lack of appetite, and yellowing of the eyes or skin.

Patients should consult a doctor immediately in case any of these side effects become apparent or persist.

Amoksiklav, like most antibiotic medicines, can cause a patient to have diarrhoea, which could indicate a new infection. Patients should immediately notify a doctor especially if their bowel is watery or has blood in it. Never use a medication to control the diarrhoea unless prescribed by your doctor.

Patients who have kidney or liver illness should inform their physician about their condition prior to taking Amoksiklav. These conditions can prevent a patient from taking Amoksiklav or can require an adjustment in the dosage.

Amoksiklav has the following structural formula:

• Molecular formula of amoksiklav is C8H9NO5 • Chemical IUPAC Name is (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid • Molecular weight is 199.1608 g/mol • Amoksiklav available. 250mg tablets, 500mg tablets, 625mg tablets, 875mg tablets

Generic name: Clavulanate

Motrin - Pain Relief, Infibu

Motrin is used for treating rheumatoid arthritis, osteoarthritis, menstrual cramps, or mild to moderate pain. Motrin is an NSAID. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Use Motrin as directed by your doctor.

Take Motrin by mouth with or without food. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.

Take Motrin with a full glass of water (8 oz/240 mL) as directed by your doctor.

If you miss a dose of Motrin and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about the proper use of Motrin .

Store Motrin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Motrin out of the reach of children and away from pets.

Active Ingredient: Ibuprofen.

Do NOT use Motrin if:

you are allergic to any ingredient in Motrin

you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

you have recently had or will be having bypass heart surgery

you are in the last 3 months of pregnancy.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Motrin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal product, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)

if you have a history of swelling or fluid buildup, lupus, asthma, or growths in the nose (nasal polyps), or mouth inflammation

if you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

if you have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse.

Some medicines may interact with Motrin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased

Probenecid because it may increase the risk of Motrin 's side effects

Cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Motrin

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Motrin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Motrin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Motrin may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Motrin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Serious stomach ulcers or bleeding can occur with the use of Motrin. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Motrin with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Motrin has ibuprofen in it. Before you start any new medicine, check the label to see if it has ibuprofen in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Do not take aspirin while you are using Motrin unless your doctor tells you to.

Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

Use Motrin with caution in the elderly; they may be more sensitive to its effects, including stomach bleeding and kidney problems.

Motrin should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: Motrin may cause harm to the fetus. Do not take it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Motrin while you are pregnant. It is not known if Motrin is found in breast milk. Do not breastfeed while taking Motrin .

All medicines can cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; dizziness; gas; headache; heartburn; nausea; stomach pain or upset.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; stiff neck; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Phenergan - Sleep Aid, Oftalgesic

Product Description Common use Phenergan is an antihistamine used to treat different types of allergy symptoms, including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. It works by decreasing the effects of histamine, a chemical the body releases in response to certain irritants. Also Phenegran is used as a sedative and sleep aid for all types of patients and prevent or control nausea and vomiting, treat motion sickness. You can use it with other medications, for pain after surgery also.

Dosage and direction Take it orally with or without food/milk. It is better take this medication with food if you want to avoid stomach upset. For treating allergy the recommended dose is 25 mg before sleeping. You can repeat the dose within two hours if necessary. For treating motion sickness the recommended dose is 25 mg twice daily. Note: this instruction presented here just for review. It's very necessary to consult your doctor before using. It will help you to get better results.

Precautions Do not give this drug to patients in coma. Do not use alcohol while taking Phenergan because it can extreme drowsiness. Avoid alcohol use. Phenergan may increase sensitivity to sunlight. Wear a sunscreen and protective clothing when you are exposed to the sun, it'll help you to avoid a heat stroke. Phenergan should not be used during pregnancy, becoming pregnancy or lactating without telling your doctor. Do not use before breast-feeding without doctor's advice.

Contraindications Phenergan is not allowed to children under 2 years of age. Phenergan is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. Also this drug is contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.

Possible side effect They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include: twitching, or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking; feeling restless, jittery, or agitated; high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing; feeling like you might pass out; seizure (convulsions); pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms; decreased night vision, tunnel vision, watery eyes, increased sensitivity to light; hallucinations, agitation; nausea and stomach pain, skin rash, and jaundice (yellowing of the skin or eyes); urinating less than usual or not at all; joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious include: dizziness, drowsiness, anxiety; blurred vision, dry mouth, stuffy nose; ringing in your ears; weight gain, swelling in your hands or feet; impotence, trouble having an orgasm; or constipation. If you experience one of them stop using Phenegran and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction Phenergan interact with such drugs as: lithium (Eskalith, Lithobid); atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop); blood pressure medication such as guanadrel (Hylorel), guanethidine (Ismelin), propranolol (Inderal), and others; a blood thinner such as warfarin (Coumadin); bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva); bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), solifenacin (Vesicare), and others; an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), selegiline (Eldepryl, Emsam); medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma); medicine to treat stomach ulcer or irritable bowel syndrome, such as dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), mepenzolate (Cantil), or propantheline (Pro-Banthine). Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.

Overdose Symptoms of Phenergan overdose may include: severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting. If you experience one of them call your doctor immediately.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Amatol - Military Wiki, Almatol

Amatol

Not to be confused with the barbiturate amytal .

Amatol is a highly explosive material made from a mixture of TNT and ammonium nitrate. [1] The British name originates from the words ammonium and toluene (a raw material of TNT). Similar mixtures were known as Schneiderite in France. Amatol was used extensively during World War I and World War II. typically as an explosive in military weapons such as aircraft bombs. shells. depth charges. and naval mines. [2] It was eventually replaced with alternative explosives such as composition B. torpex. and tritonal.

Contents

Manufacture and use Edit

Amatol exploits synergy between TNT and ammonium nitrate. TNT has higher explosive velocity and brisance. but is deficient in oxygen. Oxygen deficiency causes black smoke residue [3] from a pure TNT explosion. The oxygen surplus of ammonium nitrate increases the energy release of TNT during detonation. Depending on the ratio of ingredients used, amatol leaves a residue of white or grey smoke after detonation. Amatol has a lower explosive velocity and correspondingly lower brisance than TNT but is cheaper to make.

Amatol allowed supplies of TNT to be expanded considerably, with little reduction in the destructive power of the final product, so long as the amount of TNT in the mixture did not fall below 60%. Mixtures containing as little as 20% TNT were for less demanding uses.

It must be remembered that TNT is 50% deficient in oxygen. Amatol is oxygen balanced and is therefore more effective than pure TNT when exploding underground or underwater. RDX is also has a negative oxygen balance. Oxygen balanced filaments also have application for nuclear weapons ; the Hiroshima bomb "Little Boy " used amatol.

Relatively unsophisticated cannery equipment can be adapted to amatol production. TNT is gently heated with steam or hot water until it melts, acquiring the physical characteristics of a syrup. Then the correct weight ratio of powdered ammonium nitrate is added and mixed in. Whilst this mixture is still in a molten state, it is poured into empty bomb casings and allowed to cool and solidify. However, the lowest grades of amatol could not be produced by casting molten TNT. Instead, flaked TNT was thoroughly mixed with powdered ammonium nitrate and then compressed or extruded. [2]

The colour of amatol ranges from off-white to slightly yellow or pinkish brown, depending on the mixture used and remains soft for long periods of storage. It is also hygroscopic. which complicates long-term storage. [4] To prevent moisture problems, amatol charges were coated with a thin layer of pure molten TNT or alternatively bitumen. Long-term storage was rare during wars because munitions charged with amatol were generally used soon after manufacture.

Amatol should not be stored in containers made from copper or brass, as it can form unstable compounds sensitive to vibration. [4] Pressed, it is relatively insensitive but may be detonated by severe impact, whereas when cast, it is extremely insensitive. Primary explosives such as mercury fulminate were often used as a detonator. in combination with an explosive booster charge such as tetryl.

The explosive charges hidden in HMS Campbeltown during the St. Nazaire Raid of 1942 contained amatol. The British X class midget submarines which planted explosive charges beneath the German battleship Tirpitz in September 1943 carried two "saddle charges" containing four Long ton of amatol. Warheads for the German V-1 flying bomb and V-2 rockets also contained amatol.

A derivative of amatol is amatex. consisting of 51% ammonium nitrate, 40% TNT, and 9% RDX.

Ammonite Edit

Amatol is rare today, except in legacy munitions or unexploded ordnance. A form of amatol exists under a different name — ammonite . Ammonite is a civilian explosive, generally comprising a 20/80 mixture of TNT and ammonium nitrate. Typically, it is used for quarrying or mining purposes. It is a popular civil engineering explosive in Eastern Europe and China.

Because the proportion of TNT is significantly lower than in its military counterpart, ammonite has much less destructive power; given ammonite's use, this is not a problem. In general, a 30 kilogram charge of ammonite is roughly equivalent to 20 kilograms of TNT.

Amatol, the town Edit

Amatol was the name given to a munitions factory and planned community built by the United States government in Mullica Township, New Jersey during World War I. [5] After the war, the town was dismantled. The Atlantic City Speedway was built on part of the Amatol site in 1926.

References Edit

See also Edit

Gastran

GasTran TM

A New Class of High-Selectivity Membranes for Bubble-Free Gas Transfer to or from Aqueous Solutions

GasTran TM membranes are composite hollow fibers with a thin polymeric layer on the surface of a porous support. When gas is transfered, the membrane functions mainly as a barrier between gas-gas and gas-liquid phases. To perform well, it must have a high mass transfer rate for gases, be essentially impermeable to water, and have good mechanical strength. NeoMecs applies such a layer by the precisely controlled process of plasma polymerization.

Practical use of the GasTran hollow-fiber membrane has led to the module design shown below. It has a compact and convenient structure which provides many options of total membrane surface area through choice of fiber bundle size. The external shell has versatile connections to bring into the module the two fluid streams separated by a membrane barrier.

For information on NeoMecs's products and services, please send e-mail to neomecsi@skypoint. com . phone us at 952-946-0506, or FAX your request to 952-941-7019.

This page, and all contents, are Copyright (C) 1996 by NeoMecs Inc. United States

Is Cholelithiasis A Side Effect Of Climopax ( ), Climopax

About this FactMed analysis covering adverse side effect reports of CLIMOPAX patients who developed CHOLELITHIASIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking CLIMOPAX reported CHOLELITHIASIS to the FDA. A total of 23 CLIMOPAX drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between CLIMOPAX and CHOLELITHIASIS. In doing so, we compare CLIMOPAX with other drugs that cause CHOLELITHIASIS, to help you evaluate whether or not CLIMOPAX causes CHOLELITHIASIS. Likewise, this page shows the most highly-reported side effects of CLIMOPAX, so you can see if CHOLELITHIASIS ranks among CLIMOPAX's most well-known side effects.

Summary Statistics Reports of CLIMOPAX causing CHOLELITHIASIS: 1 Reports of any side effect of CLIMOPAX. 23 Percentage of CLIMOPAX patients where CHOLELITHIASIS is a reported side effect: 4.3478%

FDA reports of any drug causing CHOLELITHIASIS. 20521 Average percentage for all medicated patients where CHOLELITHIASIS is reported as a complication: 0.1286%

Physician opinion on CLIMOPAX as adverse event culprit:

Sildenafil Medlineplus Drug Information, Zilden

Sildenafil

Why is this medication prescribed?

Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).

How should this medicine be used?

Sildenafil comes as a tablet and suspension (liquid; Revatio only) to take by mouth.

If you are taking sildenafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity. Sildenafil usually should not be taken more than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take sildenafil less often. You can take sildenafil with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work.

If you are taking sildenafil to treat PAH, follow your doctor's directions and the guidelines in this paragraph. You will probably take sildenafil three times a day with or without food. Take sildenafil at around the same times every day, and space your doses about 4 to 6 hours apart.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sildenafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well for 10 seconds before each use to mix the medication evenly. Use the oral syringe provided with your medication to measure and take your dose. Follow the manufacturer's directions to use and clean the oral syringe. Do not mix the liquid with other medications or add anything to flavor the medication.

If you are taking sildenafil for erectile dysfunction, your doctor will probably start you on an average dose of sildenafil and increase or decrease your dose depending on your response to the medication. Tell your doctor if sildenafil is not working well or if you are experiencing side effects.

If you are taking sildenafil for PAH, you should know that sildenafil controls PAH but does not cure it. Continue to take sildenafil even if you feel well. Do not stop taking sildenafil without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking sildenafil,

tell your doctor and pharmacist if you are allergic to sildenafil, any other medications, or any of the ingredients in sildenafil products. Ask your pharmacist for a list of the ingredients.

do not take sildenafil if you are taking or have recently taken riociguat (Adempas) or nitrates (medications for chest pain) such as isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others). Nitrates come as tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are not sure whether any of your medications contain nitrates.

do not take street drugs containing nitrates such as amyl nitrate and butyl nitrate ('poppers') while taking sildenafil.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax, in Jalyn), and terazosin; amlodipine (Norvasc, in Amturnide, in Tekamlo); certain antifungals such as itraconazole (Onmel, Sporanox) and ketoconazole (Nizoral); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain barbiturates such as butalbital (in Butapap, in Fioricet, in Fiorinal, others) and secobarbital (Seconal); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal LA, InnoPran); bosentan (Tracleer); cimetidine ; efavirenz (Sustiva, in Atripla); erythromycin (E. E.S. E-Mycin, Erythrocin); HIV protease inhibitors including amprenavir (Agenerase; no longer available in the U. S.), atazanavir (Reyataz, in Evotaz), darunavir (Prezista, in Prezcobix), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), and tipranavir (Aptivus); nevirapine (Viramune); other medications or devices to treat erectile dysfunction; medications for high blood pressure; certain medications for seizures including carbamazepine (Carbatrol, Epitol, Tegretol, others), phenobarbital, and phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with sildenafil, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

tell your doctor what herbal products you are taking or plan to take, especially St. John's wort.

tell your doctor if you smoke, if you have ever had an erection that lasted for several hours, and if you have recently lost a large amount of body fluids (dehydration). This can happen if you are sick with fever, diarrhea, or vomiting; sweat a lot; or do not drink enough liquids. Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease (PVOD; blockage of veins in the lungs); a stomach ulcer; heart, kidney, or liver disease; a heart attack; an irregular heartbeat; a stroke; chest pain; high or low blood pressure; high cholesterol; a bleeding disorder; blood circulation problems;blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); conditions affecting the shape of the penis (e. g. angulation, cavernosal fibrosis, or Peyronie's disease); or diabetes. Also tell your doctor if you or any of your family members have or have ever had an eye disease such as retinitis pigmentosa (an inherited eye condition that causes loss of vision) or if you have ever had sudden severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see.

if you are a woman and you are taking sildenafil to treat PAH, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking sildenafil, call your doctor.

if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking sildenafil.

if you are taking sildenafil to treat erectile dysfunction, tell your doctor if you have ever been advised by a healthcare professional to avoid sexual activity for medical reasons or if you have ever experienced chest pain during sexual activity. Sexual activity may be a strain on your heart, especially if you have heart disease. If you experience chest pain, dizziness, or nausea during sexual activity, call your doctor immediately and avoid sexual activity until your doctor tells you otherwise.

tell all your healthcare providers that you are taking sildenafil. If you ever need emergency medical treatment for a heart problem, the healthcare providers who treat you will need to know when you last took sildenafil.

What special dietary instructions should I follow?

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.

What should I do if I forget a dose?

If you are taking sildenafil for erectile dysfunction, you are unlikely to miss a dose since this medication is taken as needed, not on a regular dosing schedule.

If you are taking sildenafil for PAH, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Sildenafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

headache

heartburn

diarrhea

flushing (feeling of warmth)

nosebleeds

difficulty falling asleep or staying asleep

numbness, burning, or tingling in the arms, hands, feet, or legs

muscle aches

changes in color vision (seeing a blue tinge on objects or having difficulty telling the difference between blue and green)

sensitivity to light

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

sudden severe loss of vision (see below for more information)

blurred vision

sudden decrease or loss of hearing

ringing in ears

dizziness or lightheadedness

fainting

chest pain

worsening shortness of breath

erection that is painful or lasts longer than 4 hours

itching or burning during urination

rash

Some patients experienced a sudden loss of some or all of their vision after they took sildenafil or other medications that are similar to sildenafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication. If you experience a sudden loss of vision while you are taking sildenafil, call your doctor immediately. Do not take any more doses of sildenafil or similar medications such as tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor.

There have been reports of heart attack, stroke, irregular heartbeat, bleeding in the brain or lungs, high blood pressure, and sudden death in men who took sildenafil for erectile dysfunction. Most, but not all, of these people had heart problems before taking sildenafil. It is not known whether these events were caused by sildenafil, sexual activity, heart disease, or a combination of these and other causes. Talk to your doctor about the risks of taking sildenafil.

Some patients experienced a sudden decrease or loss of hearing after they took sildenafil or other medications that are similar to sildenafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication. If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking sildenafil, call your doctor immediately. If you are taking sildenafil (Viagra) for erectile dysfunction, do not take any more doses of sildenafil (Viagra) or similar medications such as tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor. If you are taking sildenafil (Revatio) for PAH, do not stop taking your medication until you talk to your doctor.

Sildenafil may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Store the suspension at room temperature or in a refrigerator, but do not freeze it. Throw away any unused suspension after 60 days. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

Risk Assessment, Lefex

Risk Assessment

Risk Assessment is a comprehensive review of a company’s activities aimed at identifying vulnerabilities and assessing the likelihood of financial or other losses.

Our practice

Risk Assessment is one of Lefex’s most reliable features. Virtually any project of ours starts with a study of the company’s financial and legal exposure.

We perform an analysis of risk factors both as part of major projects and as a stand-alone service for businesses.

What we deliver is not only a detailed report on all internal and external corporate risks, but also a custom-made solution for managing them on a long-term basis.

Using risk management tools, our experts can create a road map for business operations and identify all threats in advance, which will minimize the risk dramatically.

What is the purpose of Risk Assessment?

Companies are advised to make risk and threat assessments virtually at every stage of their growth.

Risk Assessment is of greatest relevance in the following situations: the company’s entry into a market, a change in business strategies, persistent losses, and internal or external crisis.

More often than not, a company is exposed to risks even with the business running smoothly and no growth threats in sight. These are latent risks and can only be identified by highly skilled legal professionals and analysts.

Hydro Flask, Do-Hydro

Lifetime Warranty

We are so convinced that the Hydro Flask® is the best double wall vacuum insulated bottle available that we guarantee every Hydro Flask® product with a limited lifetime warranty against manufacturer defects! Although our lifetime warranty does not cover ordinary wear and tear, including dents, scratches, powder coat chips from the flask being dropped, damaged, etc. it does cover manufacturing defects.

Before submitting a warranty claim, please read the following:

Broken or leaking caps: If your cap breaks or you notice a leak, do not send your flask to us. Instead, simply fill out our form below. Please note you may be required to send us a photo of your cap to validate the claim. You will be responsible for the shipping charge to have the flask returned if you send the flask to us.

Flasks that no longer insulate: You can test the insulation property of your flask at home by adding boiling hot water to the flask. After 5 minutes, feel the outside of the flask (below the neck). If you feel any hot spots, the vacuum has been compromised and you are eligible for a replacement.

Flasks that are damaged during the shipping process: Please contact us if you ordered your flask from www. HydroFlask. com and it has arrived damaged. If you use your flask, we cannot replace it due to shipping damage. We will e-mail you a pre-paid shipping label to return the damaged flask and will send out a replacement flask upon receipt.

Rough welds along the rim of your flask: Our flasks are welded at the rim and, on occasion, the welding can be uneven. If you receive a flask that has an uneven rim or lip, please contact us for a replacement.

Rattling flasks: The rattle you hear is a small metal disc that sits between the double wall of your flask that aids in the vacuum insulation process. Sometimes the disc becomes dislodged, creating a small noise or rattle. This will not affect the insulation or structural integrity of your flask. If you can live with it, so can we. However, if it is an annoyance, we will exchange it for a new flask.

Warranty claims will only be approved by Hydro Flask® if the product was purchased from an authorized dealer. This warranty is limited to the lifetime of your Hydro Flask® product, as limited by or subject to applicable law. The limited warranty provided by Hydro Flask® only covers manufacturing defects and does not include any damage or defect of any Hydro Flask® products, caused by, whether directly or indirectly, any of the following: (i) improper use or misuse of the product; (ii) damage or defect caused by cleaning, disassembly, alterations or modifications; or (iii) damage or defect caused by or resulting from wear and tear, abuse, fire, or Acts of God.

If you believe you have a defective flask, and desire to make a warranty claim, please complete the form below. Alternatively, if you purchased your Hydro Flask® product from an authorized Hydro Flask® retailer, please contact the authorized Hydro Flask® retailer that you purchased your Hydro Flask® product from to make a warranty claim and avoid unnecessary shipping and handling charges and delay.

Please note your Warranty Claim Hydro Flask® will be replaced by the same size and color Hydro Flask. If the size and color are no longer available, it will be replaced by one of similar size and color and will not be of lesser MSRP value. Unfortunately, replacement flasks under warranty cannot be customized. If you have a flask with a custom logo, we are not able to screen print or engrave the artwork on your return flask (sorry). Once we have your defective flask, please allow 10-15 days for return delivery. You will receive a confirmation email once the flask has been processed for a warranty exchange and an additional email once the replacement flask has departed our warehouse. Those that have purchased engraved flasks will not get an engraved flask sent to them under our warranty replacement policy.

In no event shall Hydro Flask® be liable or responsible for any damage, loss, cost or expense, including incidental or consequential damages. Some states do not allow the exclusion or limitation of incidental or consequential damages, so the above exclusion or limitation may not apply to you. This warranty gives you specific legal rights, and you may also have other rights which vary from state to state.

Please sign in before you enter your warranty details

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Bula Do Medicamento Donaren, Donaren

Cloridrato de trazodona

FORMAS FARMACEUTICAS E APRESENTACOES - Donaren® Comprimidos revestidos de 50 mg - Caixas contendo 60 comprimidos Comprimidos revestidos de 100 mg - Caixas contendo 20 e 30 comprimidos

Cada comprimido revestido contem: Cloridrato de Trazodona. 50 mg e 100 mg *Excipientes q. s.p. 1 comprimido *Excipientes: croscarmelose sodica, celulose microcristalina, fosfato de calcio tribasico, lactose, estearato de magnesio, dioxido de titanio, hidroxipropilmetilcelulose e polietilenoglicol.

INFORMACOES AO PACIENTE - Donaren® Acao esperada do medicamento: DONAREN® e um antidepressivo, usado no tratamento de depressao com ou sem episodios de ansiedade, neuropatia2 diabetica e outros tipos de dores cronicas e tratamento da depressao Maior.

Cuidados de armazenamento: DONAREN® deve ser mantido em sua embalagem original, na temperatura ambiente (15 a 30°C), e ao abrigo da luz e da umidade.

Prazo de validade: O prazo de validade para comprimidos revestidos e de 24 meses. Verifique a validade impressa na embalagem. Nao utilize medicamento com o prazo de validade vencido, alem de nao produzir efeito, pode ser prejudicial a saude.

Gravidez1 e lactacao3: A seguranca do uso de DONAREN® durante a gravidez1 e a amamentacao4 nao foi estabelecida ainda. Informe ao seu medico a ocorrencia de gravidez1 na vigencia do tratamento ou apos o seu termino. Informe ao medico se esta amamentando.

Cuidados de administracao: Siga a orientacao do seu medico, respeitando sempre os horarios, as doses e a duracao do tratamento. Observe a prescricao e nao altere as dosagens ou os intervalos da administracao do medicamento. Os comprimidos de Trazodona devem ser administrados logo apos uma refeicao ou um pequeno lanche. Pode ocorrer tontura5, caso o comprimido seja tomado em jejum.

Interrupcao do tratamento: Nao interrompa o tratamento nem tome qualquer outro medicamento sem o conhecimento de seu medico. Informe ao seu medico sobre qualquer outra medicacao que esteja tomando, pois podera ser necessario alterar as doses ou o medicamento prescrito.

Reacoes adversas: Informe ao seu medico o aparecimento de reacoes desagradaveis para o controle adequado da medicacao. No inicio do tratamento voce pode sentir tontura5, sonolencia, nausea6, gosto desagradavel e boca seca. Em geral, essas reacoes desaparecem com a continuidade do uso do medicamento, mas devem ser informadas ao medico. Os pacientes em tratamento com o cloridrato de Trazodona, que apresentarem erecao prolongada ou inapropriada do penis devem suspender o medicamento e consultar o medico.

TODO MEDICAMENTO DEVE SER MANTIDO FORA DO ALCANCE DAS CRIANCAS.

Ingestao concomitante com outras substancias: Abstenha - se de bebidas alcoolicas durante o tratamento. A Trazodona pode intensificar o efeito do alcool, barbituricos e outros depressores do SNC (sistema nervoso7 central). Informe ao seu medico sobre qualquer medicamento que esteja utilizando, antes do inicio ou durante o tratamento. Nao se automedique e siga rigorosamente as instrucoes de seu medico.

Contra - indicacoes e precaucoes: DONAREN® e contra-indicado a pacientes que apresentam alergias a trazodona. Realize os exames de controle sanguineo durante o tratamento. Durante o tratamento, visite regularmente seu medico e realize os exames complementares solicitados. Informe ao seu medico caso sofra de qualquer problema cardiaco, renal8 ou doenca no figado9. Os antidepressivos podem diminuir a capacidade mental e/ou fisica exigidas para o desempenho de tarefas potencialmente perigosas, tais como dirigir veiculos ou operar maquinas; caso voce exerca atividade que requeira atencao, observe com cuidado o seu estado geral para evitar acidentes. Informe ao seu medico sobre qualquer medicamento que esteja usando, antes do inicio ou durante o tratamento. Nao deve ser usado durante a gravidez1 e a lactacao3. Riscos da auto - medicacao: DONAREN® so deve ser utilizado sob exclusiva prescricao e acompanhamento medico.

NAO TOME REMEDIO SEM O CONHECIMENTO DO SEU MEDICO; PODE SER PERIGOSO PARA A SUA SAUDE.

INFORMACOES TECNICAS - Donaren®

Modo de Acao DONAREN® e um novo antidepressivo cujo principio ativo e o Cloridrato de Trazodona. A Trazodona e um derivado da triazolopiridina que difere quimicamente dos demais antidepressivos disponiveis. Embora a Trazodona apresente certa semelhanca com os benzodiazepinicos, fenotiazidas e antidepressivos triciclicos, seu perfil farmacologico difere desta classe de drogas. O mecanismo da acao antidepressiva da Trazodona no homem ainda nao esta completamente elucidado. Estudos em animais demonstram inibicao seletiva da recaptura da serotonina no cerebro e outras acoes farmacologicas em receptores adrenergicos. Em animais, a Trazodona inibe seletivamente a absorcao da serotonina pelos sinaptossomas do cerebro e potencializa as alteracoes do comportamento induzidas pelo precursor de serotonina, o 5- hidroxitriptofano. Os efeitos da trazodona na conducao cardiaca de caes anestesiados sao qualitativamente dissimilares e quantitativamente menos pronunciados do que aqueles observados com antidepressivos triciclicos. A trazodona nao e um inibidor da monoaminoxidase e, ao contrario de drogas do tipo anfetaminas, nao estimula o sistema nervoso7 central. A atividade anticolinergica da Trazodona e menor do que a apresentada pelos antidepressivos triciclicos, em estudos animais, e este fato foi confirmado em estudos clinicos em pacientes deprimidos. DONAREN® e indicado para o tratamento da depressao Maior. A eficacia da Trazodona foi demonstrada em administracoes tanto em pacientes hospitalizados quanto em tratamento ambulatorial, e em pacientes deprimidos com ou sem ansiedade. Episodio Depressivo Maior implica humor depressivo ou disforico importante ou relativamente persistente (quase todo dia durante pelo menos 2 semanas) que interfere na atividade normal diaria, e inclui pelo menos quatro dos oito seguintes sintomas10: alteracao do apetite, alteracoes do sono, agitacao ou lentidao psicomotora, perda do interesse nas atividades usuais ou diminuicao do impulso sexual, aumento de fadiga, sentimentos de culpa ou de auto - desmerecimento, pensamento lento ou diminuicao da concentracao, e ideias ou tentativas suicidas.

Farmacocinetica A Trazodona e bem absorvida apos a administracao oral. Sua absorcao pode ser aumentada quando administrada com alimentos. Quando a Trazodona e tomada logo apos a ingestao de alimentos, pode haver um aumento na quantidade da droga absorvida, uma diminuicao da concentracao maxima e prolongamento do tempo para atingir a concentracao maxima. A concentracao plasmatica maxima e atingida aproximadamente em uma hora apos a administracao quando o cloridrato de Trazodona e ingerido com estomago11 vazio e duas horas apos a administracao quando ingerido com alimentos. A taxa de ligacao proteica e alta (89- 95%). A biotransformacao e hepatica, extensa, sendo a excrecao renal8 (75%) e biliar (20%). A eliminacao da Trazodona e bifasica, consistindo de uma fase inicial (meia - vida de 3 a 6 horas), seguida de uma fase mais lenta (meia-vida de 5 a 9 horas), e nao e afetada pela presenca ou ausencia de alimento. Visto que a depuracao da Trazodona e bastante variavel, em alguns pacientes, a droga podera se acumular no plasma12. Os pacientes que respondem ao tratamento com Trazodona, um terco dos pacientes hospitalizados e metade dos pacientes ambulatoriais, apresentam uma reacao terapeutica significativa no final da primeira semana de tratamento. Tres quartos de todos os pacientes que apresentam resposta positiva ao tratamento demonstram um efeito terapeutico significativo ao final da segunda semana. Em geral, sao necessarias de 2 a 4 semanas para uma reacao terapeutica significativa para um quarto dos pacientes que respondem ao tratamento.

INDICACOES - Donaren® Depressao mental com ou sem episodios de ansiedade. Dor neurogenica (neuropatia2 diabetica) e outros tipos de dores cronicas. Tratamento da Depressao Maior.

Em pacientes com hipersensibilidade a Trazodona ou aos componentes da formula. No infarto do miocardio13 (periodo de recuperacao).

A TRAZODONA ESTA ASSOCIADA A OCORRENCIA DE PRIAPISMO. OS PACIENTES DO SEXO MASCULINO COM ERECOES PROLONGADAS OU COM DURACAO INADEQUADA, DEVEM SUSPENDER IMEDIATAMENTE O TRATAMENTO COM O MEDICAMENTO E CONSULTAR O MEDICO. Foram relatados casos de detumescencia do priapismo e erecoes do penis induzidas por medicamentos por injecao14 intracavernosa com estimulantes alfa - adrenergicos tais como epinefrina e metaraminol. Em um caso de priapismo (de 12 a 24 horas de duracao) em paciente tratado com Trazodona, no qual foi aplicada a injecao14 intra-cavernosa de epinefrina, ocorreu detumescencia imediata com retorno de atividade erectil normal. Esse procedimento deve ser realizado sob a supervisao de um urologista15 ou um medico familiarizado com o tratamento e nao deve ser iniciado sem consulta urologica, se o priapismo persistir por mais de 24 horas. A Trazodona nao e recomendada para uso durante a fase inicial de recuperacao do infarto do miocardio13.

GERAIS: Administrar DONAREN® durante ou logo apos as refeicoes a fim de evitar irritacao gastrica. Embora 75% dos pacientes apresentem melhora em 2 semanas, as vezes e necessario um periodo superior a 30 dias para produzir efeitos terapeuticos significativos. Suspender a medicacao gradualmente. Evitar bebidas alcoolicas ou outros depressores do SNC. Cuidado ao levantar - se ou sentar-se abruptamente, pode ocorrer vertigem16. Evitar funcoes onde a falta de atencao aumenta o risco de acidentes. O risco/beneficio deve ser considerado em situacoes clinicas como doencas cardiacas, alcoolismo, comprometimento hepatico ou renal8 e gravidez1.

A possibilidade de suicidio em pacientes seriamente deprimidos e inerente a doenca e pode persistir ate que ocorra melhora significativa. Portanto, deve - se prescrever o menor numero possivel de comprimidos adequando o tratamento as necessidades do paciente. Ha relatos sobre a ocorrencia de hipotensao17, incluindo a hipotensao17 ortostatica e sincope18 em pacientes sob tratamento com Cloridrato de Trazodona. A administracao concomitante de terapia anti - hipertensiva com Trazodona pode exigir uma reducao da dose do medicamento anti-hipertensivo. Pouco se sabe sobre a interacao entre a Trazodona e anestesicos em geral; portanto, antes de cirurgia eletiva, o tratamento com Trazodona deve ser interrompido pelo tempo que for clinicamente viavel. Deve - se tomar precaucoes ao administrar Cloridrato de Trazodona a pacientes com disturbios cardiacos e tais pacientes devem ser monitorados cuidadosamente, visto que medicamentos antidepressivos (incluindo a Trazodona) estao associados com a ocorrencia de arritmias cardiacas. Estudos clinicos recentes relativos a pacientes com disturbios cardiacos preexistentes indicam que a Trazodona pode ser arritmogenica em alguns pacientes desse grupo. Devido a sua fraca atividade adrenolitica, a Trazodona pode provocar bradicardia19 e hipotensao17 acompanhada de eventual taquicardia20 compensatoria, o que exige cuidados no uso em pacientes cardiopatas, especialmente nos que apresentam disturbios de conducao ou bloqueio auriculo-ventricular. Assim como ocorre com todos os antidepressivos, o uso da Trazodona deve ser recomendado pelo medico levando em consideracao se os beneficios da terapia superam os fatos potenciais de risco. Como foi relatada a ocorrencia do priapismo em pacientes que receberam Cloridrato de Trazodona, os pacientes com erecao prolongada ou inapropriada do penis devem interromper imediatamente o tratamento com o medicamento e consultar o medico (veja ADVERTENCIAS). A Trazodona pode intensificar o efeito do alcool, barbituricos e outros depressores do SNC (sistema nervoso7 central). A Trazodona deve ser administrada logo apos uma refeicao ou um pequeno lanche. Em qualquer paciente, a absorcao total do medicamento pode ser ate 20% maior quando e tomado com alimento ao inves de ingeri - lo com estomago11 vazio. O risco de tontura5/delirio21 pode aumentar sob condicoes de jejum.

TESTES LABORATORIAIS - Donaren® Ocasionalmente foram observadas contagens baixas de celulas brancas e neutrofilos no sangue22 em pacientes que receberam Cloridrato de Trazodona que, em geral, nao exigiram a suspensao do medicamento; contudo, o tratamento deve ser suspenso em qualquer paciente cuja contagem de celulas brancas ou neutrofilos absolutos no sangue22 caia abaixo dos niveis normais. Contagens de celulas brancas e diferenciais sao recomendadas para pacientes que apresentem febre23 e dor de garganta (ou outros sinais24 de infeccao25) durante a terapia.

CARCINOGENESE, MUTAGENESE, DIMINUICAO DA FERTILIDADE - Donaren®

Nao houve evidencia de ocorrencia de carcinogenese relacionada com o medicamento ou, com a dosagem em ratos que receberam o Cloridrato de Trazodona em doses diarias orais ate 300 mg/kg durante 18 meses.

GRAVIDEZ1 - Donaren® Nao ha estudos adequados e bem controlados sobre os efeitos em mulheres gravidas. A Trazodona nao deve ser usada durante os tres primeiros meses da gravidez1, e nos meses restantes apenas se o beneficio esperado justificar o risco potencial para o feto.

A Trazodona e/ou seus metabolitos foram encontrados no leite de ratos lactantes26, sugerindo que o medicamento pode ser excretado no leite humano. Nao se recomenda administrar o Cloridrato de Trazodona para lactantes26.

USO PEDIATRICO - Donaren® A seguranca e eficacia em criancas abaixo de 18 anos ainda nao esta bem determinada.

O uso em pacientes idosos, acima de 65 anos de idade, exige uma administracao reduzida, conforme especificado em Posologia e Modo de Usar.

INTERACOES MEDICAMENTOSAS - Donaren®

Deve - se evitar a administracao do medicamento concomitante a terapia por eletrochoque pela ausencia de pesquisa nessa area. Ha relatos de ocorrencia de aumento e diminuicao de tempo de protrombina em pacientes sob tratamento com warfarina e Trazodona. A Trazodona na dose de 175 mg/dia nao intervem na terapia anticoagulante27 com cumarinicos, embora modere o efeito da heparina. O uso concomitante com alcool ou outros depressores do SNC, pode causar depressao excessiva do Sistema Nervoso7 Central. O uso concomitante de anti - hipertensivos pode causar hipotensao17 grave. A Trazodona na dose de 100 a 300 mcg/kg produz uma inibicao dose-dependente do efeito anti-hipertensivo da clonidina. Ha relatos da ocorrencia de aumento nos niveis de digoxina ou fenitoina no sangue22 em pacientes que recebem Trazodona juntamente com um desses medicamentos. Foi descrito um caso de possivel intoxicacao digitalica precipitada pela Trazodona em um paciente geriatrico, sugere - se especial cuidado nestes casos. Nao se conhece sobre a ocorrencia de interacoes entre inibidores da monoaminoxidase (IMAO) e a Trazodona. Devido a ausencia de pesquisa clinica, se os inibidores da MAO forem suspensos um pouco antes ou forem administrados concomitantemente a Trazodona, a terapia deve ser iniciada com cautela aumentando - se gradualmente a dosagem ate que se obtenha a reacao esperada.

REACOES ADVERSAS - Donaren®

Reacoes mais frequentes: sonolencia, boca seca, gosto desagradavel, nausea6, vomito28 e cefaleia29. Assim como outras drogas psicoativas, a Trazodona causa sedacao, mas seu efeito sobre o sono difere de todas as demais drogas da classe, pois nao deprime o sono REM como a fenotiazida que deprime o comportamento de auto - estimulacao pela acao da anfetamina e produz um bloqueio alfa-adrenergico, mas ao contrario das demais drogas a Trazodona apresenta minimos efeitos anticolinergicos e nao antagoniza a dopamina central.

Reacoes ocasionais ou raras: priapismo, efeitos no SNC, batimento cardiaco irregular, hipotensao17, excitacao anormal, visao turva, constipacao30, diarreia31, dor muscular, debilidade ou fraqueza anormal. Houve ocorrencias ocasionais de bradicardia19 sinusal em estudos a longo prazo. Outros relatos mais raros, incluem: acatisia, reacao alergica32, anemia33, dores no peito, fluxo alterado de urina34, alteracao da menstruacao35, flatulencia, hematuria36, hipersalivacao, hipomania, dificuldade da fala, impotencia37, aumento do apetite, aumento de libido, contracoes musculares, entorpecimentos e ejaculacao retrograda. O tratamento com a Trazodona foi associado a erecao do penis e priapismo. Para avaliar esta reacao adversa, um estudo duplo - cego em 6 pacientes saudaveis, comparou a acao da Trazodona com a trimipramina (triciclico). Durante o tratamento com Trazodona houve um aumento estatisticamente significativo da erecao noturna que passou de 177±21 minutos com trimipramina para 285±115 minutos com Trazodona (p www. apsen. com. br

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Interactions Between Theobron Oral And Xanthine-Derivatives-Adenosine-Hexobendine-Regadenoson, Theob

Interactions

Adenosine; Hexobendine; Regadenoson/Xanthine Derivatives

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e. g. doctor or pharmacist) for more information.

How the interaction occurs:

Xanthine derivatives, including caffeine, prevent adenosine, hexobendine and regadenoson from working.

What might happen:

Your adenosine or hexobendine may not work as well.

What you should do about this interaction:

Adenosine and regadenoson are usually used during surgical procedures or in a hospital. Hexobendine is usually used for heart disease. If you are to have either inpatient or outpatient surgery or tests, are to be admitted to the hospital, or started on hexobendine, make sure that all the healthcare professionals are aware of all the different medicines that you are taking. This includes prescription medicines, herbal drugs, and nutraceuticals. If you are scheduled for a cardiac stress test, your doctor may instruct you to avoid caffeine before your test. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Fredholm BB. On the mechanism of action of theophylline and caffeine. Acta Med Scand 1985;217(2):149-53.

2.Smits P, Schouten J, Thien T. Cardiovascular effects of two xanthines and the relation to adenosine antagonism. Clin Pharmacol Ther 1989 Jun; 45(6):593-9.

3.Adenoscan (adenosine) US prescribing information. Astellas Pharma US, Inc. August, 2014.

4.Lexiscan (regadenoson) US prescribing information. Astellas Pharma US, Inc. September, 2014.

5.Hansing CE, Folts JD, Afonso S, Rowe GG. Systemic and coronary hemodynamic effects of hexobendine and its interaction with adenosine and aminophylline. J Pharmacol Exp Ther 1972 Jun;181(3):498-511.

6.Maxwell DL, Fuller RW, Conradson TB, Dixon CM, Aber V, Hughes JM, Barnes PJ. Contrasting effects of two xanthines, theophylline and enprofylline, on the cardio-respiratory stimulation of infused adenosine in man. Acta Physiol Scand 1987 Nov;131(3):459-65.

7.Taddei S, Pedrinelli R, Salvetti A. Theophylline is an antagonist of adenosine in human forearm arterioles. Am J Hypertens 1991 Mar;4(3 Pt 1):256-9.

8.Minton NA, Henry JA. Pharmacodynamic interactions between infused adenosine and oral theophylline. Hum Exp Toxicol 1991 Nov;10(6):411-8.

9.Smits P, Boekema P, De Abreu R, Thien T, van 't Laar A. Evidence for an antagonism between caffeine and adenosine in the human cardiovascular system. J Cardiovasc Pharmacol 1987 Aug;10(2):136-43.

10.Smits P, Schouten J, Thien T. Respiratory stimulant effects of adenosine in man after caffeine and enprofylline. Br J Clin Pharmacol 1987 Dec; 24(6):816-9.

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Graphical representation showing How to order at International Drug Mart

Generic Name: Budesonide

What is Generic for Budelin* used for?

Generic for Budelin* (Budesonide) is an inhalation medication prescribed to treat asthma attacks and mild-to-moderate Crohn's disease. It belongs to a class of drugs called corticosteroids that prevent asthma symptoms such as shortness of breath, troubled breathing, and wheezing. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Generic for Budelin*?

The dosage of Generic for Budelin* prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. The following dosage information includes the common dose of Generic for Budelin*If your dose is different, do not follow the dosage described below unless your physician has approved.

Generic for Budelin* is usually used once or twice a day.

What if you miss a dose of Generic for Budelin*?

If your physician has instructed or directed you to use Generic for Budelin* medication in a regular schedule and you have missed a dose of this medicine, use it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Generic for Budelin*?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Generic for Budelin*, seek medical attention immediately.

What other drugs could interact with Generic for Budelin*?

It may be noted that drugs other than those listed above may also interact with Generic for Budelin*.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Generic for Budelin*, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Generic for Budelin* can interact with antibiotics, HIV/AIDS medicines, tricyclic antidepressants, and antifungal medicines.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Generic for Budelin*?

Like other medicines, Generic for Budelin* can cause some side effects. If they do occur, the side effects of Generic for Budelin* are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Generic for Budelin* cannot be anticipated. If any side effects of Generic for Budelin* develop or change in intensity, the doctor should be informed as soon as possible.

Generic for Budelin* can cause side effects such as mouth sores, cough, headache, runny nose, nosebleeds, nausea, vomiting, diarrhea, and stomach pain. Some of the serious side effects of this drug are swelling of the face, difficulty breathing, severe acne, and vision problems. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Generic for Budelin*.

What are the questions to ask your doctor before taking Generic for Budelin*?

Is it possible for me to use Generic for Budelin* with other drugs? Should certain beverages, foods and other products be avoided when I use Generic for Budelin*? What are the possible drug interactions of Generic for Budelin*? How will Generic for Budelin* work in my body? How should Generic for Budelin* be used? How to reduce the risk of Generic for Budelin* drug interactions and side effects?

Note

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Generic for Budelin* is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Before using Generic for Budelin*, tell your doctor if you have a history of tuberculosis, liver disease, and osteoporosis. Also, tell your doctor if you are pregnant or plan to become pregnant or breast-feeding. Avoid being near individuals who have chicken pox or measles.

Flagystatine, Flagystatine

Nystatin

Click for further information on drug naming conventions and International Nonproprietary Names .

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Types Of Coughs - Chesty, Dry, Mucus & Tickly - Benylin® Uk, Benylin

Types of Cough

Coughing starts when part of your breathing passage becomes inflamed or irritated by matter such as dust, smoke or mucus.

A cough is simply a reflex that tries to remove the irritant and to clear the airway.

Broadly speaking there are two main types of cough:

Productive coughs which produce excess mucus or phlegm

Unproductive coughs which produce no mucus or phlegm

Based on consumer perception, these two types can be further differentiated into mucus and chesty coughs (productive) & dry and tickly coughs (unproductive).

For more details on the different types of cough please read below.

Chesty cough

What does a chesty cough feel like?

When you’ve got a chesty cough it can feel tight as if someone was squeezing your chest too hard. Find out how BENYLIN ® Chesty Cough products can help you ease the symptoms of your chesty cough. (Not a suitable treatment for asthma)

Why do you have a chesty cough?

Chesty coughs are caused by a build-up of phlegm in the lungs and result in chest congestion. Chest congestion is a common symptom of respiratory tract infections. Sometimes irritants such as dust, bacteria or viruses can enter your lungs and cause an infection. This can result in inflammation of the airways and result in extra phlegm (or mucus) in your lungs. The cough mechanism kicks in to try to get rid of it.

Mucus cough

What does a mucus cough feel like?

When a wet mucus cough sits on your chest it feels heavy as though an octopus is weighing down on your chest. Find out how BENYLIN ® Mucus Cough products can help you ease the symptoms of your mucus cough.

Why do you have a mucus cough?

Mucus producing tissue lines our lungs. The function of mucus is to protect the body from dust, bacteria, viruses and other inhaled debris. Even when you are not ill, your body produces mucus to trap external particles and keep them from entering the lungs, acting as a filter.

When you get a cold, more mucus is produced to trap the viruses or bacteria. This mucus can gather in the respiratory system and a cough reflex is triggered to help remove it.

When mucus builds up in the chest, it can be thick and difficult to get rid of by coughing. Therefore it is useful to have something that can help loosen the mucus and ease bronchial congestion – relieving that feeling of heaviness on your chest.

Tickly cough

What does a tickly cough feel like?

A tickly cough can be quite irritating. It feels uncomfortable and can bother you while talking as if someone is tickling your throat with a feather. You would feel it in your throat rather than in the chest as opposed to the chesty and mucus coughs. Find out how BENYLIN ® Tickly Cough can help you ease the symptoms of your tickly cough.

Why do you have a tickly cough?

The irritated area in the throat produces a tickly sensation causing you to cough. A sore throat can also be experienced with a tickly cough, as the constant coughing may irritate the throat.

Dry cough

What does a dry cough feel like?

When you experience a hacking dry cough it can be intense and painful. Sometimes you even want to avoid coughing, because you are afraid it will hurt. A dry cough can be felt in your throat rather than in the chest as opposed to the chesty and mucus coughs. Find out how BENYLIN ® Dry Cough products can help you ease the symptoms of your dry cough.

Why do you have a dry cough?

Dry coughs are caused by an inflammation of the upper airways. There is no mucus or phlegm produced. A dry cough can be caused by infections such as a cold or the flu. Dry coughs can also be triggered by other environmental irritants such as fumes, dust or cigarette smoke.

When to contact your GP:

If your cough lasts longer than three weeks after a viral infection or if it’s starting to get worse instead of better you should contact your GP. You should also contact your GP when you:

Experience breathing difficulties

Experience chest pain

Cough up blood

Have other symptoms that worry you (weight loss, swelling in the neck…)

BENYLIN ® is not indicated in chronic coughs.

Protonix Uses, Dosage - Side Effects, Protonil

Protonix

Protonix (pantoprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome .

Protonix is not for immediate relief of heartburn symptoms.

Important information

You should not use Protonix if you are allergic to pantoprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox).

Protonix is not for immediate relief of heartburn symptoms.

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Take Protonix for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.

Protonix should not be taken together with atazanavir (Reyataz) or nelfinavir (Viracept). Tell your doctor if you are taking either of these medications to treat HIV or AIDS.

Some conditions must be treated long-term with Protonix. Chronic use has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.

Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.

Before taking this medicine

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

You should not use Protonix if you are allergic to pantoprazole or to similar medicines such as lansoprazole (Prevacid), esomeprazole (Nexium), omeprazole (Prilosec, Zegerid), or rabeprazole (AcipHex).

To make sure Protonix is safe for you, tell your doctor if you have:

severe liver disease;

low levels of magnesium in your blood;

low bone mineral density (osteopenia).

Taking a proton pump inhibitor such as pantoprazole may increase your risk of bone fracture in the hip, wrist, or spine . This effect has occurred mostly in people who have taken the medicine long term or at high doses, and in those who are age 50 and older. It is not clear whether Protonix is the actual cause of an increased risk of fracture.

Protonix is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Pantoprazole can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Protonix is not approved for use by anyone younger than 5 years old.

How should I take Protonix?

Take Protonix exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Protonix tablets can be taken with or without food. Protonix oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break the tablet . Swallow it whole.

The oral granules should be mixed with applesauce or apple juice. Do not use any other type of liquid or soft food. Sprinkle the granules directly onto 1 teaspoon of applesauce or apple juice. Stir for 5 seconds and swallow this mixture right away without chewing. Do not save the mixture for later use.

To give Protonix granules through a nasogastric (NG) feeding tube:

Attach a 60-milliliter syringe to the NG tube and remove the plunger. Hold the syringe high enough to prevent any bends in the tube.

Empty the Protonix granules into the syringe barrel and mix in 2 teaspoons of apple juice.

Add 2 more teaspoons of apple juice to the syringe to rinse the granules through. Tap or shake the syringe as the juice empties into the tube.

Rinse with 2 teaspoons of apple juice at least twice more to make sure there are no granules remaining in the syringe or NG tube.

Take Protonix for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.

If you use Protonix for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.

Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine.

If you use Protonix for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.

This medicine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking Protonix.

Store Protonix at room temperature away from moisture and heat.

Protonix dosing information

Usual Adult Dose for Erosive Esophagitis:

Treatment of Erosive Esophagitis: 40 mg orally once a day for up to 8 weeks; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Maintenance of Healing of Erosive Esophagitis: 40 mg orally once a day. Controlled studies have been limited to 12 months of Protonix therapy.

Usual Adult Dose for Gastroesophageal Reflux Disease:

Parenteral: 40 mg once a day for 7 to 10 days, administered via intravenous infusion over a period of 15 minutes. Intravenous therapy should be discontinued as soon as the patient is able to resume oral therapy.

Oral: 40 mg orally once a day, for short-term administration (up to 8 weeks); however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Usual Adult Dose for Duodenal Ulcer:

Study (n=54) 40 mg orally once a day, dose was increased every 12 weeks by 40 mg increments to a maximum of 120 mg per day, for 28 weeks. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete duodenal ulcer healing in up to 87% and 94% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Gastric Ulcer:

40 mg orally once a day. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete gastric ulcer healing in up to 87% and 97% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Helicobacter pylori Infection:

Study (n=242) - Triple therapy: 40 mg orally twice daily for 7 days, commonly in conjunction with clarithromycin and either amoxicillin or metronidazole to eradicate Helicobacter pylori, followed with 40 mg Protonix orally once daily until day 28. Triple therapy has resulted in eradication rates of greater than 95%.

The QUADRATE Study (n=405) - Quadruple therapy: 40 mg orally twice daily for 7 days, concomitantly with bismuth subcitrate and tetracycline, both four times daily, and metronidazole 200 mg three times daily and 400 mg at bedtime. Helicobacter Pylori eradication was achieved in 82% of patients.

Usual Adult Dose for Zollinger-Ellison Syndrome:

Parenteral: 80 mg every 12 hours, administered by 15-minute infusion. Daily doses higher than 240 mg administered in equally divided doses by 15-minute infusion, or administered for more than 6 days have not been studied.

Oral: 40 mg twice daily, to a maximum of 240 mg per day. Some patients have received treatment with Protonix for more than 2 years.

Usual Adult Dose for Stress Ulcer Prophylaxis:

Study (n=21) - Stress Ulcer bleeding prophylaxis in the Critical Care Setting: 80 mg twice daily, as a bolus infusion over a period of 15 minutes, to a maximum daily dose of 240 mg, divided into three equal doses.

Study (n=20 ) - Peptic Ulcer rebleeding prophylaxis after hemostasis in the Critical Care Setting: 80 mg IV bolus, followed by continuous infusion of 8 mg/hr for 3 days, after which therapy may be continued with an oral PPI.

Usual Adult Dose for Peptic Ulcer:

Study (n=21) - Stress Ulcer bleeding prophylaxis in the Critical Care Setting: 80 mg twice daily, as a bolus infusion over a period of 15 minutes, to a maximum daily dose of 240 mg, divided into three equal doses.

Study (n=20 ) - Peptic Ulcer rebleeding prophylaxis after hemostasis in the Critical Care Setting: 80 mg IV bolus, followed by continuous infusion of 8 mg/hr for 3 days, after which therapy may be continued with an oral PPI.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Protonix?

This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Protonix side effects

Get emergency medical help if you have signs of an allergic reaction to Protonix: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

severe stomach pain, nausea, vomiting, and weight loss;

diarrhea that is watery or bloody;

kidney problems - urinating more or less than usual, blood in your urine, swelling, rapid weight gain; or

symptoms of low magnesium - dizziness, confusion; fast or uneven heart rate; tremors (shaking) or jerking muscle movements; feeling jittery;muscle cramps, muscle spasms in your hands and feet; cough or choking feeling.

Common Protonix side effects may include:

cold symptoms such as stuffy nose, sneezing, sore throat;

stomach pain, gas, nausea, vomiting;

mild diarrhea; or

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Protonix?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Protonix, especially:

warfarin (Coumadin, Jantoven);

HIV or AIDS medicine - atazanavir, nelfinavir; or

iron-containing medicines - ferrous fumarate, ferrous gluconate, ferrous sulfate, and others.

This list is not complete. Other drugs may interact with pantoprazole, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about Protonix (pantoprazole)

Consumer resources

Professional resources

Other formulations

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about Protonix.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Protonix only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 16.01. Revision Date: 2015-01-20, 11:04:42 AM.

Drug Status

Rosicon-Mf, Rosicon-Mf

Why register with MediGuard?

We are a free monitoring service designed for patients like you who want to be in the driver seat of your medical treatment. We have a community of more than 2.6 million members and offer the services below.

Medication Information Personalized Risk Rating Easy to understand overview Serious Side Effects Printable Medication List

Information you can understand Overview on Safety Alerts & Recalls Overview of Medications & Conditions

Community of patients Members’ Feedback Members Treatment Satisfaction

Health condition information Easy to understand overview Commonly Used Medications

Safety checks Safety Alerts & Recalls Drug - Drug Interaction Drug - Condition Interaction

Research participation Option to participate in medical surveys & studies*

Metformin with Rosiglitazone

Why register with MediGuard?

We are a free monitoring service designed for patients like you who want to be in the driver seat of your medical treatment. We have a community of more than 2.6 million members and offer the services below.

Medication Information Personalized Risk Rating Easy to understand overview Serious Side Effects Printable Medication List

Information you can understand Overview on Safety Alerts & Recalls Overview of Medications & Conditions

Community of patients Members’ Feedback Members Treatment Satisfaction

Health condition information Easy to understand overview Commonly Used Medications

Safety checks Safety Alerts & Recalls Drug - Drug Interaction Drug - Condition Interaction

Research participation Option to participate in medical surveys & studies*

Metformin with Rosiglitazone

Buy Allergies - Rotadin (Brand Name Alavert) Online - Order Cheap Loratadine - Purchase Allergies -

Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Alavert is used for relieving symptoms of seasonal allergies.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not crush, chew, or break the regular loratadine tablet. Swallow the pill whole. Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon.

Alavert is usually taken once per day. Follow your doctor's instructions.

To take Alavert orally disintegrating tablet:

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Using dry hands, remove the tablet and place it on your tongue. It will begin to dissolve right away.

Take Alavert by mouth with food.

Store at room temperature between 20 and 25 degrees C and away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep Alavert out of the reach of children and away from pets.

You should not take Alavert if:

You are allergic to loratadine or to desloratadine (Clarinex). Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

kidney disease; Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Loratadine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Loratadine disintegrating tablets (Claritin Reditab, Alavert) may contain phenylalanine. Talk to your doctor before using this form of loratadine if you have phenylketonuria (PKU). Do not give this medication to a child younger than 6 years old without the advice of a doctor.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

fast or uneven heart rate;

feeling like you might pass out;

jaundice (yellowing of your skin or eyes);

seizures (convulsions).

Call your doctor at once if you noticed these serious side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

headache;

skin rash;

nervousness;

nosebleed;

feeling tired or drowsy;

eye redness, blurred vision;

stomach pain, diarrhea;

dry mouth, sore throat hoarseness.

Buy Amolex Duo - Amoxicillin, Clavulanate - Online Without Prescriptions, Amolex Duo

Augmentin (Amolex duo)

Augmentin is used for treating infections caused by certain bacteria. Augmentin is a penicillin antibiotic. It works by killing sensitive bacteria.

Use Augmentin as directed by your doctor.

Take Augmentin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, take Augmentin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Augmentin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Augmentin.

Store Augmentin at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Augmentin out of the reach of children and away from pets.

Active Ingredient: Amoxicillin/clavulanate potassium.

Do NOT use Augmentin if:

you are allergic to any ingredient in Augmentin or another penicillin antibiotic (eg, ampicillin)

you have a history of liver problems or yellowing of the eyes or skin caused by Augmentin

you have infectious mononucleosis (mono)

you are taking a tetracycline antibiotic (eg, doxycycline)

you have recently received or will be receiving live oral typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Augmentin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of allergies, asthma, hay fever, or hives

if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)

if you have kidney problems or gonorrhea

if you have a history of liver problems or yellowing of the eyes or skin.

Some medicines may interact with Augmentin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Probenecid because it may increase the amount of Augmentin in your blood

Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Augmentin's effectiveness

Methotrexate because the risk of its side effects may be increased by Augmentin

Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Augmentin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Augmentin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Augmentin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Augmentin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Augmentin only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Augmentin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Augmentin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Augmentin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Augmentin. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.

Diabetes patients - Augmentin may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Augmentin for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Augmentin with caution in the elderly; they may be more sensitive to its effects, especially patients with kidney problems.

Use Augmentin with extreme caution in children younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

Augmentin should not be used in children who weigh less than 88 lbs (40 kg); safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Augmentin while you are pregnant. Augmentin is found in breast milk. If you are or will be breast-feeding while you use Augmentin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Tompkins Financial Advisors Relays Advice For Planning For Long-Term Care - Oklahoma City, Ok - News

Tompkins Financial Advisors Relays Advice for Planning for Long-Term Care - News9.com - Oklahoma City, OK - News, Weather, Video and Sports |

19 Sep, 2016 – Nearly 70 percent of Americans will depend on long-term care at some point during their lifetimes after reaching age 65. Despite those odds, few people plan for how they will be able to finance their long-term care needs, says Susan Herendeen, CFP®, a wealth advisor and vice president with Tompkins Financial Advisors in Rochester, NY.

Long-term care doesn’t only refer to the services provided in a nursing home. The most common type of long-term care is home-based care, and services may also be provided in settings such as assistant living facilities and adult day care centers.

There are three levels of long-term care:

• Skilled care: Round-the-clock care given by professional health care providers, such as nurses, therapists or aides under a doctor’s supervision

• Intermediate care: Professional health care services provided on a less frequent basis

• Custodial care: Personal care delivered by family health caregivers, nurses’ aides, or home health workers who provide assistance with activities of daily living, such as bathing, eating and dressing

Whatever type of care you may need, you can count on it being expensive. “Our financial planners recommend that people assess their ability to cover the cost of long-term care years before the services are needed, just as they would plan for their retirement,” says Herendeen.

Costs of Long-Term Care

The cost of long-term care can be daunting, especially if you are suddenly faced with the prospect of having to enter a nursing home. Paying for long-term care can quickly absorb your income and deplete your savings, which is why you need to plan for how you will finance it.

Here are some of the average costs for long-term care* in the United States:

• A semi-private room in a nursing home costs $6,235 per month, or $74,820 per year • A private room in a nursing home costs $6,965 per month, or $83,580 per year • A one-bedroom unit in an assisted living facility costs $3,293 per month • A home health aide costs $21 per hour

*U. S. Department of Health and Human Services, December 1, 2015

Evaluating Available Sources to Pay for Long-Term Care

Many people assume that Medicare, the federal health insurance program for older Americans, will pay for long-term care. But Medicare only provides limited coverage for nursing home care. Under current regulations, Medicare covers up to 100 days in a nursing home after you have spent three days in a hospital and as long as you need skilled care. After that period ends, you are responsible for 100 percent of any remaining costs.

Medicaid, the joint federal-state program, is used by two-thirds of nursing home residents to pay some of their long-term care expenses. But many seniors have too much income and too many assets to qualify for Medicaid. And while Medicaid covers nursing home care, it provides only limited coverage for home health care in some states.

You may consider using your income, savings, investments and assets (such as your home) to pay for long-term care. That will give you the most control over where and how you receive care. The high costs of long-term care, however, may make it difficult for you to afford extended care when you need it.

Buying Long-Term Care Insurance

Tompkins Insurance financial planners advise that investing in long-term care insurance can help preserve assets and guarantee that you’ll have access to a range of care options. In exchange for your premium payments, an insurance company will cover part of your future long-term care costs. The cost of long-term care insurance, however, can be expensive, so you need to evaluate whether you can afford the premiums on an ongoing basis.

How much you pay for long-term health insurance depends primarily on your age — the younger you are when you buy a policy, the lower your premium will be. It also varies according to the following benefits:

• Benefit amount: The maximum amount your policy will pay for your care each day • Benefit period: The length of time your policy pays benefits • Elimination period: The number of days you must pay for your own care before the policy begins paying for care • Types of facilities included: Most policies cover care in a range of settings, including your own home, assisted living facilities, and nursing homes • Inflation protection: This allows your benefit to increase by a certain percentage each year to keep pace with rising prices

If you are thinking of purchasing long-term care insurance, you should contact a financial planner to help you compare policies. Regardless of whether you buy the insurance or not, the sooner you begin planning for long-term care, the more options you’ll have in the future.

Some of this material was prepared by Forefield/Broadridge for Tompkins Financial Advisors. The opinions voiced in this material are for general information only and are not intended to provide specific advice or recommendations for any individual.

We suggest that you discuss your specific situation with your financial advisor prior to investing.

Investing involves risk including loss of principal. No strategy assures success or protects against loss.

Securities and advisory services offered through LPL Financial, a Registered Investment Advisor, Member FINRA/SIPC. Insurance products offered through LPL Financial or its licensed affiliates. LPL Financial is a separate entity from Tompkins Financial Advisors. The investment products sold through LPL Financial are not insured Tompkins Trust Company deposits and are not FDIC insured. These products are not obligations of Tompkins Trust Company and are not endorsed, recommended or guaranteed by Tompkins Trust Company or any government agency. The value of the investment may fluctuate, the return on the investment is not guaranteed, and loss of principal is possible. Tompkins Financial Corporation, Tompkins Trust Company and Tompkins Wealth Advisors are not registered broker/dealers and are not affiliated with LPL Financial.

Information contained on this page is provided by an independent third-party content provider. Frankly and this Station make no warranties or representations in connection therewith. If you are affiliated with this page and would like it removed please contact pressreleases@franklyinc. com

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Avirax Description

Generic Avirax is an anti-infectious medicine which is taken to fight with symptoms of herpes virus.

Generic Avirax works by killing bacteria of herpes virus.

Generic name of Generic Avirax is Acyclovir.

Brand name of Generic Avirax is Avirax.

Avirax Dosage

Generic Avirax is available in:

200mg Low Dosage400mg Standard Dosage800mg Increased Dosage

Generic Avirax is available in tablets (200 mg, 400 mg, 800 mg), capsules and suspension which should be taken orally.

It would be better to take Generic Avirax at the same time every day with full glass of water.

Generic Avirax in liquid forms should be shaken before usage. It is better to take Generic Avirax with food then without.

Do not stop taking it suddenly.

Avirax Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Avirax Overdose

If you overdose Generic Avirax and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Avirax overdosage: problems with urinating, hallucinations, seizure.

Avirax Side effects

Generic Avirax has its side effects. The most common are:

dizzinessnauseaswellingdiarrheaproblems with appetitevomitingstomach painheadache

Less common but more serious side effects during taking Generic Avirax:

allergy reactions (urticaria, breathing difficulties, rash, and eruption)abnormal weaknesseasy bruisingproblems with urinatingbleeding

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Avirax Contra-indications

Be careful with Generic Avirax while you are pregnant or have nurseling. Generic Avirax can pass in breast milk and harm your baby.

Do not use Generic Avirax if you are allergic to Generic Avirax components or to valacyclovir (Valtrex).

Be careful with Generic Avirax if you are taking such medicines as probenecid (Benemid).

Do not take such medicines as moisturizers while taking Generic Avirax because moisturizers can give effect of demulcent.

Be careful with Generic Avirax if you have kidney disease.

Herpes virus is very infectious. Be attentive and avoid close contacts with surrounding people to protect them from herpes. Do not touch the infected place. Wash your hand if you touch it.

If you have genital herpes you should use latex condom while having sex.

Do not stop taking it suddenly.

Avirax Frequently asked questions

Q: How does Generic Avirax work?

A: Generic Avirax works by killing bacteria of herpes virus.

Q: Can I take Generic Avirax if I am pregnant?

A: Be careful with Generic Avirax if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Avirax can pass in breast milk and harm your baby.

Q: What should I do if I miss a dose or overdose?

A: If you miss a dose you should take it as soon as you remember it. If it is the time for the next dose you should just continue your regular dosing schedule. Do not take double dose. Do not take Generic Avirax in larger amounts. If you overdose Generic Avirax, you should just visit you doctor or health care provider immediately.

Q: What is Generic Avirax?

A: Generic Avirax is a medicine which is used to reduce the development and the contagion of the virus called herpes. Generic Avirax also treats different infections caused by herpes such as cold sores, genital herpes, chicken pox and shingles.

Q: Can other drugs be taken with Generic Avirax?

A: Do not take such medicines as moisturizers while taking Generic Avirax because moisturizers can give effect of demulcent. Be careful with Generic Avirax if you are taking such medicines as probenecid (Benemid).

Q: What is brand name of Generic Avirax?

A: Brand name of Generic Avirax is Avirax.

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Erythromycin (Zuracyn)

Erythromycin is used for treating infections caused by certain bacteria. It is also used to prevent bacterial endocarditis and attacks of rheumatic fever. Erythromycin is a macrolide antibiotic. It works by slowing the growth of, or sometimes killing, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Use Erythromycin as directed by your doctor.

Take Erythromycin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Swallow Erythromycin whole. Do not break, crush, or chew before swallowing.

Do not eat grapefruit or drink grapefruit juice while you use Erythromycin.

Erythromycin works best if taken at the same time each day.

To clear up your infection completely, take Erythromycin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Erythromycin, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Erythromycin.

Store Erythromycin at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tightly closed. Keep Erythromycin out of the reach of children and away from pets.

Do NOT use Erythromycin if:

you are allergic to any ingredient in Erythromycin

you are taking astemizole, cisapride, conivaptan, diltiazem, dofetilide, an ergot alkaloid (eg, dihydroergotamine, ergotamine), everolimus, an HIV protease inhibitor (eg, ritonavir), an imidazole (eg, ketoconazole), nilotinib, pimozide, a QT-prolonging agent (eg, quinidine, sotalol), a quinolone (eg, ciprofloxacin), a streptogramin (eg, quinupristin/dalfopristin), terfenadine, or verapamil.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Erythromycin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have diarrhea or a stomach or intestinal infection

if you have a history of kidney or liver disease, heart problems, a fast or irregular heartbeat, myasthenia gravis, or the blood disease porphyria.

Some medicines may interact with Erythromycin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Astemizole, cisapride, diltiazem, dofetilide, an HIV protease inhibitor (eg, ritonavir), imidazoles (eg, ketoconazole), nilotinib, pimozide, a QT-prolonging agent (eg, quinidine, sotalol), a quinolone (eg, ciprofloxacin), a streptogramin (eg, quinupristin/dalfopristin), terfenadine, or verapamil because side effects, such as heart toxicity or irregular heartbeat, may occur. Check with your doctor if you have questions about which medicines may affect your heartbeat.

Conivaptan, ergot alkaloids (eg, dihydroergotamine, ergotamine), or everolimus because the risk of their side effects may be increased by Erythromycin

Many prescription and nonprescription medicines (eg, used for aches and pains, allergies, blood thinning, breathing problems, cancer, diabetes, erection problems, gout, heart problems, high blood calcium levels, high blood pressure, high cholesterol, HIV infection, inflammation, infections, low blood sodium levels, migraine, mood or mental problems, overactive bladder, Parkinson disease, prevention of organ transplant rejection, seizures, stomach problems, trouble sleeping), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may also interact with Erythromycin. Ask your doctor or pharmacist if you are unsure if any of your medicines might interfere with Erythromycin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Erythromycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Erythromycin only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Erythromycin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Erythromycin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Tell your doctor or dentist that you take Erythromycin before you receive any medical or dental care, emergency care, or surgery.

Rarely, patients taking Erythromycin have developed reversible hearing loss. The risk is greater if you have kidney problems or you take high doses of Erythromycin. Contact your doctor if you develop decreased hearing or hearing loss.

Erythromycin may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Erythromycin.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Erythromycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Erythromycin while you are pregnant. Erythromycin is found in breast milk. If you are or will be breast-feeding while you use Erythromycin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; loss of appetite; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; decreased hearing or hearing loss; irregular heartbeat; muscle weakness; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe stomach pain or cramps; symptoms of liver problems (eg, yellowing of the skin or eyes, pale stools, severe or persistent nausea, vomiting, loss of appetite, or dark urine).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Amovet is used for:

Treating infections caused by certain bacteria. It is also used with other medicines to treat Helicobacter pylori infection and ulcers of the small intestines. Amovet is a penicillin antibiotic. It works by killing sensitive bacteria.

Do NOT use Amovet if:

you are allergic to any ingredient in Amovet or another penicillin antibiotic (eg, ampicillin)

you have infectious mononucleosis (mono)

you are taking a tetracycline antibiotic (eg, doxycycline)

Contact your doctor or health care provider right away if any of these apply to you.

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Diclofenac is used primarily for the treatment of inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also effective in treating soft tissue inflammations due to tendinitis and bursitis, and treating dysmenorrhea (menstrual cramps). Diclofenac is an NSAID. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Use Diclofenac as directed by your doctor!

Take Diclofenac by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.

Take Diclofenac with a full glass of water (8 oz/240 mL) as directed by your doctor.

If you miss a dose of Diclofenac, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Diclofenac.

Store Diclofenac at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diclofenac out of the reach of children and away from pets.

Do NOT use Diclofenac if:

you are allergic to any ingredient in Diclofenac or to bovine (cow) protein

you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

you have recently had or will be having bypass heart surgery

you have severe kidney problems

you are in the last 3 months of pregnancy.

Contact your doctor or health care provider right away if this applies to you.

Some medical conditions may interact with Diclofenac. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of kidney or liver problems, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)

if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation

if you have high blood pressure, blood disorders (eg, porphyria), bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

if you have poor health, dehydration or low fluid volume, or low blood sodium levels, you smoke, drink alcohol, or have a history of alcohol abuse

if you are taking an antibiotic or an anti-seizure medicine. The risk of liver problems may be increased with some of these medicines.

Some medicines may interact with Diclofenac. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin), aspirin, clopidogrel, corticosteroids (eg, prednisone), heparin and other blood thinners (eg, dalteparin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased

Acetaminophen because the risk of liver problems may be increased

Probenecid because it may increase the risk of Diclofenac's side effects

Cyclosporine, lithium, metformin, methotrexate, oral NSAIDs (eg, ibuprofen), or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Diclofenac

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Diclofenac.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diclofenac may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Diclofenac may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Diclofenac with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Serious stomach ulcers or bleeding can occur with the use of Diclofenac. Taking it in high doses, for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Diclofenac with food will NOT reduce the risk of these effects. If you have severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling, contact your doctor or emergency room right away.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Diclofenac is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Do not take aspirin while you are using Diclofenac unless your doctor tells you to.

Check with your doctor or pharmacist before you take acetaminophen while you are taking Diclofenac. The risk of liver problems may be increased.

Do not switch between different forms of Diclofenac (eg, enteric-coated tablets, immediate-release tablets, capsules) unless your doctor tells you to. They may not provide the same amount of medicine to your body.

Lab tests, including kidney function, liver function, blood electrolyte levels, complete blood cell counts, and blood pressure, may be performed while you use Diclofenac. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Diclofenac with caution in the elderly; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.

Diclofenac should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: Diclofenac may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diclofenac while you are pregnant. It is not known if Diclofenac is found in breast milk. Do not breastfeed while taking Diclofenac.

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Norcet

GENERIC NAME(S): HYDROCODONE BITARTRATE/ACETAMINOPHEN

Warnings

One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. People with liver problems and children should take less acetaminophen. Ask your doctor or pharmacist how much acetaminophen is safe to take.

Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough - and-cold products). Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure.

Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. Overdose symptoms may include nausea. vomiting. loss of appetite, sweating. stomach /abdominal pain. extreme tiredness, yellowing eyes /skin. and dark urine.

Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Avoid alcohol.

Uses

This combination medication is used to relieve moderate to severe pain. It contains a narcotic pain reliever (hydrocodone ) and a non-narcotic pain reliever (acetaminophen). Hydrocodone works in the brain to change how your body feels and responds to pain. Acetaminophen can also reduce a fever.

How to use Norcet

See also Warning section.

Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).

If you are using a liquid form of this medication, use a medication measuring device to carefully measure the prescribed dose. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on weight. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.

Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

If you have ongoing pain (such as due to cancer ), your doctor may direct you to also take long-acting narcotic medications. In that case, this medication might be used for sudden (breakthrough) pain only as needed. Other non-narcotic pain relievers (such as naproxen. ibuprofen ) may also be prescribed with this medication. Ask your doctor or pharmacist if you have any questions about using this product safely with other drugs.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, watering eyes. runny nose. nausea, sweating. muscle aches) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction ). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.

Tell your doctor if your pain persists or worsens.

Side Effects

See also Warning section.

Nausea, vomiting, constipation. lightheadedness, dizziness. or drowsiness may occur. Some of these side effects may decrease after you have been using this medication for a while. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To prevent constipation. eat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative (such as a stimulant type with stool softener ).

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as agitation, confusion, hallucinations ), stomach /abdominal pain, difficulty urinating, signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss ).

Get medical help right away if you have any very serious side effects, including: fainting. seizure. slow/shallow breathing, unusual drowsiness/difficulty waking up.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

See also Warning section.

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (such as hydromorphone. morphine. codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease - COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression, thoughts of suicide), personal or family history of regular use/abuse of drugs/alcohol, stomach/intestinal problems (such as blockage, constipation, diarrhea due to infection, paralytic ileus), difficulty urinating (such as due to enlarged prostate ), gallbladder disease, disease of the pancreas (pancreatitis).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Liquid products may contain sugar and alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Children may be more sensitive to the side effects of this drug, especially slow/shallow breathing.

Older adults may be more sensitive to the side effects of this drug, especially confusion, dizziness, drowsiness, and slow/shallow breathing.

Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time. Tell the doctor right away if you notice any symptoms in your newborn baby such as slow/shallow breathing, irritability, abnormal/persistent crying, vomiting, or diarrhea.

This medication passes into breast milk and may rarely have undesirable effects on a nursing infant. Tell the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing. Consult your doctor before breast-feeding.

Interactions

See also Warning section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: certain pain medications (mixed narcotic agonist/antagonists such as pentazocine, nalbuphine, butorphanol), ketoconazole, narcotic antagonists (such as naltrexone, naloxone).

The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also affect breathing or cause drowsiness. Therefore, tell your doctor or pharmacist if you are taking other products such as alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), and other narcotic pain relievers (such as codeine, hydromorphone).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain laboratory tests (including amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow/shallow breathing, nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, slow heartbeat, yellowing eyes/skin, dark urine, loss of consciousness.

Notes

Do not share this medication with others. It is against the law.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case.

Missed Dose

If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised April 2016. Copyright(c) 2016 First Databank, Inc.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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Combination Of Alendronate Plus Alfacalcidol In The Treatment Of Osteoporosis, Tevabone

Citation

MMW Fortschr Med. 2012 Apr 5;154 Suppl 1:10-21.

Abstract

BACKGROUND: The therapeutic strategy for the reduction of fracture risk in osteoporosis should not only aim to increase bone strength, but should also improve muscle function and reduce falls without increasing the risk of significant side effects. Since 2008 a combination therapy of the antiresorptive active bisphosphonatealendronate and the pleiotropic active D-hormone-prodrug alfacalcidol is licensed in Germanyfor treatment of postmenopausal osteoporosis (Tevabone).

METHODS: In the review the results of numerous preclinical and clinical studies are reported, showing the efficacy of the combination of alendronate plus alfacalcidol.

RESULTS: In preclinical trials with ovariectomized rats the combination has shown a significantly better effect on increased bone turnover in comparison with bisphosphonate monotherapy. Presumably the "oversuppression" of bone remodeling and the resulting risk of reduced microfracture healing, which is known to occur after long-term therapy with bisphosphonates, will be reduced by the combination. Clinical studies have shown better efficacy of the combination in the increase of bone density and reduction of fracture rate (vertebral and non-vertebral fractures). Less falls were reported compared to alendronate plus genuine vitamin D. The reduction of increased parathormone levels by the alendronate plus alfacalcidol combination compared to alendronate alone was proven to increase the responder rate of the alendronate therapy. The potential risks of alendronate-induced hypocalcemia as well as alfacalcidol-induced hypercalcemia or hypercalcuria are reduced due to the contrasting mode of action of both compounds.

CONCLUSION: Treatment with the alendronate plus alfacalcidol combination meets the demands of an optimized therapy for osteoporosis. With the especially developed, self-explanatory combination package better compliance and less dispensing mistakes can be expected.

PMID

23427364 [PubMed - indexed for MEDLINE]

Article in German.

Amoxinsol 50 150g, Amoxisol

Amoxinsol 50 150g

Click the image for a larger version.

A soluble antibiotic powder for oral use containing Amoxycillin.

Chickens For the treatment of pasteurellosis and colibacillosis. Turkeys For the treatment of pasteurellosis. Ducks For the treatment of infections caused by Streptococcus bovis, Pasteurella anatipestifer and Escherichia coli. Pigs For the treatment of salmonellosis and pasteurellosis caused by isolates sensitive to amoxicillin.

Follow manufacturers dilution and administration rates for each species.

Buy Clinda Mip Clindamycin Online Without Prescriptions, Clinda Mip

Cleocin is used for treating serious infections caused by certain bacteria. Cleocin is a lincomycin antibiotic. Cleocin kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Use Cleocin as directed by your doctor.

Take Cleocin by mouth with or without food.

Take Cleocin with a full glass of water (8 oz/240 mL).

Cleocin works best if it is taken at the same time each day.

To clear up your infection completely, take Cleocin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Cleocin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cleocin.

Store Cleocin at room temperature, between 68 to 77 degrees F (20 to 25 degrees C) in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cleocin out of the reach of children and away from pets.

Active Ingredient: Clindamycin hydrochloride.

Do NOT use Cleocin if:

you are allergic to any ingredient in Cleocin or to lincomycin

you have certain intestinal problems (eg, antibiotic-associated colitis, Crohn disease, ulcerative colitis) or meningitis.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Cleocin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have diarrhea, or a history of liver problems or stomach or bowel problems (eg, colitis)

if you are allergic to tartrazine.

Some medicines may interact with Cleocin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Nondepolarizing muscle relaxants (eg, vecuronium) or succinylcholine because the risk of their side effects may be increased by Cleocin.

Erythromycin because it may decrease Cleocin's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cleocin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Cleocin only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Cleocin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Cleocin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

This product may contain tartrazine dye. This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Cleocin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Cleocin with caution in the elderly; they may be more sensitive to its effects, especially diarrhea.

Use Cleocin with extreme caution in children younger 10 years who have diarrhea or an infection of the stomach or bowel.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cleocin while you are pregnant. Cleocin is found in breast milk. If you are or will be breast-feeding while you use Cleocin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Mild diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or tarry stools; decreased urination; joint pain or swelling; red, swollen, blistered, or peeling skin; severe or persistent diarrhea; severe stomach cramps or pain; unusual vaginal discharge, itching, or odor; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Copyright © 2004-2016 All Rights Reserved

President - Definition Of President By The Free Dictionary, Presdeten

president

a. The chief executive of a republic.

b. The chief executive officer of the United States, with powers as determined by the US Constitution.

3. The chief officer of a branch of government, corporation, board of trustees, university, or similar body.

[Middle English, from Old French, from Latin praesidēns , praesident - . from present participle of praesidēre . to preside ; see preside .]

Usage Note: Occupations that are also titles, like president, doctor, and senator are normally capitalized when they precede a proper name but are not capitalized when used as common nouns: the comments of President Obama; the president's news conference.

president

1. (Government, Politics & Diplomacy) ( often capital ) the chief executive or head of state of a republic, esp of the US

2. (Commerce) (in the US) the chief executive officer of a company, corporation, etc

3. a person who presides over an assembly, meeting, etc

4. (Education) the chief executive officer of certain establishments of higher education

[C14: via Old French from Late Latin praesidens ruler; see preside]

pres•i•dent

(ˈprɛz ɪ dənt)

1. ( often cap. ) the chief of state and often the chief executive officer of a modern republic, as the United States.

2. an officer appointed or elected to preside over an organized body of persons.

3. the chief officer of a college, society, corporation, etc.

4. one who presides.

[1325–75; Middle English < Latin praesident - (s. of praesidēns ), n. use of present participle of praesidēre to preside over]

Thesaurus Antonyms Related Words Synonyms Legend:

President - the person who holds the office of head of state of the United States government; "the President likes to jog every morning"

executive branch. Executive Office of the President - the branch of the United States government that is responsible for carrying out the laws

chief of state. head of state - the chief public representative of a country who may also be the head of government

president - the chief executive of a republic

chief of state. head of state - the chief public representative of a country who may also be the head of government

president - the officer who presides at the meetings of an organization; "address your remarks to the chairperson"

Kalon Tripa - the chairman of the Kashag and essentially head of the Tibetan government-in-exile

presiding officer - the leader of a group meeting

vice chairman - one ranking below or serving in the place of a chairman

president - the head administrative officer of a college or university

academic administrator - an administrator in a college or university

President - the office of the United States head of state; "a President is elected every four years"

presidentship. presidency - the office and function of president; "Andrew Jackson expanded the power of the presidency beyond what was customary before his time"

president

1. head of state. chief of state The White House says the president would veto the bill.

president

preside

to be the chairman of a meeting etc . The prime minister presided at/over the meeting. voorsitter wees ?????? ??????? председателствам presidir predsedat den Vorsitz haben pr?sidere over; lede ????????? presidir (koosolekut) juhatama ????? ???? ?? ??? ????? ?? ???? ??? ??? toimia puheenjohtajana presider ??????? ?????? ???? predsjedati, sjediti na celu elnokol memimpin stjorna; vera i fors?ti presiedere ???? ??? ?? pirmininkauti vadit (sapulci), but par priekssedetaju menjadi pengerusi voorzitten v?re ordstyrer. lede przewodniczyc ? ???? ?? ? ?? ?? ????? ?? ???? ?????? presidir a prezida председательствовать predsedat predsedovati predsedavati presidera, leda ??????????????????? baskanl?k etmek ?? головувати ????? ???? ch? to? ??

presidency ( ?prezid?nsi ) – plural ?presidencies – noun

1. the rank or office of a president. His ambition is the presidency. presidentskap ??????? ????? президенство presidencia predsednictvi die Prasidentschaft pr?sidentembede ???????? presidencia presidendiamet ????? ?????? presidentinvirka presidence ?????? ????????? predsjednistvo elnoki tisztseg kepresidenan forsetaemb?tti presidenza ????? ?? ?, ?? prezidentyste, pirmininko pareigos prezidentura, prezidenta amats jawatan Presiden voorzitterschap. presidentschap presidentembete ; direktorstilling prezydentura ? ?????? ????? presidencia presedintie место президента predsednictvo predsednistvo mandat predsednika presidentskap, - post, - ambete ??????????????????? baskanl?k ???????????? президентство ????? ????? ch?c ch? t?ch; t?ng th?ng ????????????

2. the period of time for which somebody is president. during the presidency of Dwight D. Eisenhower. ampstyd ?????? ??????? мандат на председателство presidencia prezidentstvi Eisenhower. die Amtszeit eines Prasidenten/einer Prasidentin pr?sidenttid ????????? ?????? presidencia presidendiaeg ????? ????? ?????? presidenttikausi presidence ???????? ?????????? ????????????? predsjedanje, predsjednicki mandat elnokseg masa jabatan presiden forsetati? presidenza ?????? ?? ?? prezidentavimas, pirmininkavimas prezidentura; prezidenturas laiks memegang jawatan presiden presidentschap presidentperiode kadencja ? ??????? ????? ????? presidencia presedintie президентство prezidentstvo predsedovanje mandat predsednika presidentperiod ?????????????????????????????????? baskanl?k donemi ???????????? термін перебування на посаді президента ?????? ????? nhi?m k? ????????????

president ( ?prezid?nt ) noun

1. the leading member of a club, association etc . She was elected president of the Music Society. hoof ????? президент presidente predseda, - kyne der/die Prasident(in) pr?sident ???????? presidente esimees ???? puheenjohtaja president/-ente ???? ??????? rektor, dekan elnok ketua forseti presidente. presidentessa ?? ? prezidentas, pirmininkas prezidents; priekssedetajs presiden voorzitter leder. formann/-kvinne, president prezes ???? presidente pre­se­dinte председатель, президент; глава predseda, - kyna predsednik predsednik ordforande ?????? baskan. mudur. rektor ??,??,?? голова ??? ????? ch? t?ch ??,??,??

2. the leader of a republic. the President of the United States. president ????? ??????? президент presidente prezident, - ka der/die Prasident(in) pr?sident ???????? ??? ??????????? presidente. presidenta president ???? ????? presidentti president/-ente ???? ?????????? predsjednik elnok presiden forseti presidente. presidentessa ??? ??? prezidentas prezidents Presiden president president prezydent ?????? presidente presedinte президент prezident, - ka predsednik predsednik president ???????????? cumhurbaskan? ?? президент ??? ??????? t?ng th?ng ??

presidential ( prezi?den??l ) adjective

a presidential election. presidensieel ??????? ??????? ??????????? президентски presidencial prezidentsky Prasidentschafts-. pr?sident - ?????????? presidencial presidendi - ?????? ?? ???? ????? presidentin - presidentiel ?????? ????????? predsjednicki elnoki presiden forseta - presidenziale ???? ???? prezidento prezidenta - presiden presidents - president-. leder - prezydencki ?? ?????? ????? ????? presidencial prezidential президентский prezidentsky predsedniski predsednicki president - ????????????????????? cumhurbaskanl?g?na ait ??? президентський ?????? thu?c t?ng th?ng ???

president

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Sarcoplasm - Definition Of Sarcoplasm By The Free Dictionary, Sarcop

sarcoplasm

2+] from the mitochondria and sarcoplasmic reticulum into the sarcoplasm by enhance the stability of membrane, then reduced GP and increased pH value (den Hertog-Meischke et al.

Cluster Dextrin contributes to accelerated muscle building, because carbs help in the development of sarcoplasm. the cytoplasm of striated muscle fiber.

The muscle tissue is composed of muscle fibres with plenty of water and inorganic salts in the sarcoplasm .

70% of the water of the flesh is thought to be located in the myofibrils, 20% in the sarcoplasm and 10% in the connective tissue [17].

Enacard (5 Mg) (Canada) For Animal Use, Enacard

Enacard (5 mg) (Canada)

This page contains information on Enacard (5 mg) for veterinary use . The information provided typically includes the following:

Enacard (5 mg) Indications

Warnings and cautions for Enacard (5 mg)

Direction and dosage information for Enacard (5 mg)

Enacard (5 mg)

This treatment applies to the following species:

Dogs

Tablets for Dogs

Veterinary Use Only

For the Treatment of Heart Failure in Dogs

DIN 02060531 (1 mg), 02060558 (2.5 mg), 02060566 (5 mg), 02060574 (10 mg), 02060582 (20 mg)

Description

ENACARD (enalapril maleate) is the maleate salt of enalapril, a derivative of two amino-acids, L-alanine and L-proline. Following oral administration, enalapril is rapidly absorbed and then hydrolyzed to enalaprilat, which is a highly specific, long-acting, non-sulphydryl angiotensin converting enzyme (ACE) inhibitor. ENACARD tablets are round, non-scored, and available in five colour-coded dosage strengths.

Enacard (5 mg) Indications

ENACARD is indicated for the treatment of mild, moderate or severe heart failure in dogs caused by mitral regurgitation or dilated cardiomyopathy, in combination with standard therapy. For improved tolerance and increased survival in dogs with mild, moderate or severe heart failure.

Enacard (5 mg) Dosage And Administration

The recommended dose of ENACARD is 0.5 mg/kg administered orally s. i.d. (once a day) to dogs. In the absence of adequate clinical response within 2 weeks of initiation of therapy, the dose should be increased to b. i.d. (twice a day). This dose increase may be initiated more rapidly if indicated by signs of heart failure. Dogs should be observed closely for 48 hours following initial dosing or an increase in the dose.

Individual dosages should be administered on the basis of body weight using the appropriate tablet or combination of tablet sizes.

Safety

At the recommended dose level, ENACARD has been shown to have an adequate margin of safety in dogs with heart failure. The safety of ENACARD has been thoroughly investigated in several animal species including mice, rats, monkeys and man to assess its general toxicity. Normal dogs given 15 mg/kg/day for up to one year showed no adverse changes.

Enacard (5 mg) Caution

Renal Function Impairment

Pre-renal azotemia is usually a result of hypotension induced by impaired cardiovascular performance. On occasion, substances that deplete blood volume, such as diuretics or vasodilators (e. g. ACE inhibitors), may contribute to lowering systemic blood pressure. This may create a hypotensive state, exacerbate an existing hypotensive situation, resulting in an azotemic patient. Dogs with no detectable renal disease may develop minor and transient increases in BUN or CRT when ENACARD is administered concomitantly with a diuretic. Dosage reduction and/or discontinuation of the diuretic and/or ENACARD may be required if signs of hypotension become apparent or azotemia develops.

Dogs should be on standard therapy for heart failure at least one day prior to initiating treatment with ENACARD. Clinical manifestations of the heart failure syndrome may include pre-renal azotemia defined as elevations in the blood urea nitrogen (BUN) or creatinine (CRT), or both, provided urinalysis is normal. Renal function should be monitored both before and 2 to 7 days after starting treatment with ENACARD. The dose of diuretic or diuretic and ENACARD should be reduced if clinical signs of azotemia occur, or the concentration of blood urea nitrogen or serum creatinine increases significantly over pre-treatment levels. Periodic monitoring of renal function should be continued.

Should clinical signs of overdosage occur (e. g. azotemia) after the dose is increased from s. i.d. to b. i.d. the dose should be decreased to s. i.d.

Use In Breeding Animals

Not recommended for use in pregnant bitches. Safety in breeding dogs has not been established.

Warnings

Keep this and all drugs out of the reach of children.

In case of human ingestion, clients should be advised to contact a physician immediately.

Physicians may contact a Poison Control Center for advice concerning cases of human ingestion.

Side Effects

ENACARD has been demonstrated to be generally well tolerated. In clinical studies, the overall incidence of side effects was no greater with ENACARD than with placebo. For the most part, side effects have been mild and transient in nature, and have not required discontinuation of therapy. The following side effects have been reported.

Azotemia

In clinical trials, no significant difference in the incidence of azotemia was reported between dogs receiving standard therapy and placebo (8.3%) and dogs receiving standard therapy and ENACARD (9.4%).

General

No significant differences in the incidence of clinical signs, including lethargy, drowsiness, hypotension, disorientation or incoordination, were reported between dogs receiving standard therapy and placebo (0.8%) and dogs treated with standard therapy and ENACARD (3.0%).

Availability

Each tablet strength is supplied in blister cards containing 7 tablets each. Four blister cards are supplied in a carton box.

Storage

Store between 15°C - 25°C and protect product from light and moisture.

Merial Canada Inc. 20000 Clark Graham, Baie d’Urfé Qc H9X 4B6

® ENACARD is a registered trademark of Merial Limited.

© 2009 Merial Limited.

Merial Limited, a company limited by shares registered in England and Wales (registered number 3332751) with a registered office at PO Box 327, Sandringham House, Sandringham Avenue, Harlow Business Park, Harlow, Essex CM19 5QA, England, and domesticated in Delaware, U. S.A. as Merial LLC, and having its place of business at 3239 Satellite Boulevard, Duluth, GA, U. S.A.

NAC No.: 11820123

MERIAL CANADA INC. 20000 CLARK GRAHAM, BAIE D'URF?, QC, H9X 4B6

Cyclin - Definition Of Cyclin By The Free Dictionary, Cycin

cyclin

References in periodicals archive ?

Comparison of the cell cycle-regulating elements cyclin A, B, D, and E, and CDKIs p16 and p21 in the control group showed that cyclin D was expressed most frequently during the GO/G1 phase; the other cyclins were present in 33% of the cells, and the cyclin E level was very low.

Abnormal expression of cyclin D1 and cyclin - dependent kinases (CDKs) have been considered to be one of the most important factors in the tumourigenesis of various human malignancies.

It is reported that cyclin L2 is a novel substrate of DYRK1A.

Derailments of the RB-pathway components, cyclin D1 and cdk4 in particular, seems to participate in the endometrial cancer development in humans.

The researchers speculated that this effect stemmed from the drug's ability to block cyclin D1.

The P53-dependent transactivation of target genes including cyclin G, P21/wafl/Cipl/mdm2 underwent reversible inhibition by PFT-[alpha] as judged by Northern Blot analysis [13].

The researchers said breast cancers made of cells containing both the overactive cyclin D1-CDK4 switch and a mutated cancer-causing gene known as HER-2 were extremely difficult to treat.

In addition, melanomas that did not reveal mutations in BRAF or ras genes had frequent copy number increases and overexpression of cyclin D1 or CDK4, genes acting downstream of BRAF and ras.

Thus, up-regulation of cyclin G2 ceases cell proliferation, allowing conservation of energy (Horne et al.

In addition, mouse studies have already resulted in some discoveries about HIV, including the identification of co-receptors, cyclin T1 (a necessary co-factor for Tat and TAR during transcriptional elongation), and host factors required for viral assembly and release.

Cyclin D1 is one of a number of genes involved in the cell cycle - the mechanism through which cells to grow and divide.

Wetmore William Jewell College EXPRESSION OF CYCLIN Bi IN U373 GLIOBLASTOMA MULTIFORME CELLS.

cyclin

References in periodicals archive ?

Comparison of the cell cycle-regulating elements cyclin A, B, D, and E, and CDKIs p16 and p21 in the control group showed that cyclin D was expressed most frequently during the GO/G1 phase; the other cyclins were present in 33% of the cells, and the cyclin E level was very low.

Abnormal expression of cyclin D1 and cyclin - dependent kinases (CDKs) have been considered to be one of the most important factors in the tumourigenesis of various human malignancies.

It is reported that cyclin L2 is a novel substrate of DYRK1A.

Derailments of the RB-pathway components, cyclin D1 and cdk4 in particular, seems to participate in the endometrial cancer development in humans.

The researchers speculated that this effect stemmed from the drug's ability to block cyclin D1.

The P53-dependent transactivation of target genes including cyclin G, P21/wafl/Cipl/mdm2 underwent reversible inhibition by PFT-[alpha] as judged by Northern Blot analysis [13].

The researchers said breast cancers made of cells containing both the overactive cyclin D1-CDK4 switch and a mutated cancer-causing gene known as HER-2 were extremely difficult to treat.

In addition, melanomas that did not reveal mutations in BRAF or ras genes had frequent copy number increases and overexpression of cyclin D1 or CDK4, genes acting downstream of BRAF and ras.

Thus, up-regulation of cyclin G2 ceases cell proliferation, allowing conservation of energy (Horne et al.

In addition, mouse studies have already resulted in some discoveries about HIV, including the identification of co-receptors, cyclin T1 (a necessary co-factor for Tat and TAR during transcriptional elongation), and host factors required for viral assembly and release.

Cyclin D1 is one of a number of genes involved in the cell cycle - the mechanism through which cells to grow and divide.

Wetmore William Jewell College EXPRESSION OF CYCLIN Bi IN U373 GLIOBLASTOMA MULTIFORME CELLS.

Corotrend Cr Medicine (Basf) And Medications, Corotrend

Corotrend CR Medicine From BASF Pharmaceutical Company

Corotrend CR is manufactured by BASF. Corotrend CR is used in adults to treat dieases and it affects chemicals and nerves in the body that are involved in the cause of illness. Corotrend CR medicine contains nifedipine so before using it please read the corotrend cr prescription.

Corotrend CR Medicine Interactions

Corotrend CR contains C08CA05 - Nifedipine chemicals.

Corotrend CR Medicine Usage

There are several types of forms for Corotrend CR medicine. We have Tablet, Controlled Release Corotrend CR form. Before using Nifedipine 40 mg Corotrend CR medicine . please talk with your doctor.

Corotrend CR Indications

Use Corotrend CR medicine for disease will rapidly heal with its active ingredients.

Price Of Corotrend CR Medicine

The price range for corotrend cr can be changeable about its mg and forms. We assume that corotrend cr price is: 2 - 8.99 USD.

Use only the brand and form of corotrend cr that your doctor has prescribed. Check your medicine each time you get a refill at the pharmacy, to make sure you have received the correct form of this medication.

Copyright 2016 © - MedicineDef. com Medicine Definitions Information Resource. Medicine prescriptions gathers from online resources and they are not %100 true. Please talk with your doctor first.

Activella Oral Reviews And User Ratings Effectiveness, Ease Of Use, And Satisfaction, Activella

User Reviews & Ratings - Activella oral

« Activella oral Information

Current Rating: 5

Comment: I have been taking this drug for 6 months. No more hot flashes. My mood has improved and my hair stopped falling out. Was very hungry when I first started taking it, but that was only in the first few weeks. I am very happy with it so far.

Comment: I have been taking this drug for 6 months. No more hot flashes. My mood has improved and my hair stopped falling out. Was very hungry when I first started taking it, but that was only in the first few weeks. I am very happy with it so far. Hide Full Comment

12 people found this review helpful. Was this review helpful? Yes | No

Condition: "Change of Life" Signs

1/23/2015 1:14:33 AM

Reviewer: CoolSleep, 55-64 Female on Treatment for 2 to less than 5 years (Patient)

Current Rating: 5

Current Rating: 5

Current Rating: 5

Comment: This RX has been a lifesaver. I was having hot flashes ever hour and 45 minutes and couldn't sleep at night. Now I have zero hot flashes and can sleep again.

Comment: This RX has been a lifesaver. I was having hot flashes ever hour and 45 minutes and couldn't sleep at night. Now I have zero hot flashes and can sleep again. Hide Full Comment

7 people found this review helpful. Was this review helpful? Yes | No

Condition: "Change of Life" Signs

7/28/2014 4:01:54 PM

Reviewer: Cindy, 45-54 Female on Treatment for less than 1 month (Patient)

Current Rating: 5

Current Rating: 5

Current Rating: 5

Comment: I have been on this medication for 3 weeks, I began to notice a change within 2 weeks with less hot flashes. Hot flashes did seem to get worse for the first week, However, are completely gone now. I am currently experiencing bleeding. is this normal? does it eventually stop? I also experience anxiety, however, I experienced that before and don't think this drug has anything to do with tha. Show Full Comment

Comment: I have been on this medication for 3 weeks, I began to notice a change within 2 weeks with less hot flashes. Hot flashes did seem to get worse for the first week, However, are completely gone now. I am currently experiencing bleeding. is this normal? does it eventually stop? I also experience anxiety, however, I experienced that before and don't think this drug has anything to do with that. Hide Full Comment

2 people found this review helpful. Was this review helpful? Yes | No

Condition: "Change of Life" Signs

7/28/2014 9:01:35 AM

Reviewer: Chipper, 45-54 Female on Treatment for 1 to less than 2 years (Patient)

Current Rating: 4

Current Rating: 5

Current Rating: 4

Comment: I have been taking Activella for about 18 months and suddenly experienced face hives, face swelling, chapped upper lip and crepe-y eye lids. I stopped taking the drug for 2 weeks and although I'm not my usual chipper self (as I was ON Activella), the swelling, crepe-y-ness and chapped upper lip are subsiding. I'm not positive these symptoms are a reaction to the drug - but curious if anyon. Show Full Comment

Comment: I have been taking Activella for about 18 months and suddenly experienced face hives, face swelling, chapped upper lip and crepe-y eye lids. I stopped taking the drug for 2 weeks and although I'm not my usual chipper self (as I was ON Activella), the swelling, crepe-y-ness and chapped upper lip are subsiding. I'm not positive these symptoms are a reaction to the drug - but curious if anyone else has experienced something similar. Hide Full Comment

3 people found this review helpful. Was this review helpful? Yes | No

Condition: "Change of Life" Signs

6/8/2014 5:31:18 PM

Reviewer: Female (Patient)

Current Rating: 1

Current Rating: 3

Current Rating: 1

Comment: I was diagnosed as post menopausal and was prescribed this med and in the month that I have been taking it I have bled for 3 weeks.

Comment: I was diagnosed as post menopausal and was prescribed this med and in the month that I have been taking it I have bled for 3 weeks. Hide Full Comment

1 person found this review helpful. Was this review helpful? Yes | No

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