Gita - Definition Of Gita By The Free Dictionary, Gitas

Gita - (Hinduism) the sacred `song of God' composed about 200 BC and incorporated into the Mahabharata (a Sanskrit epic); contains a discussion between Krishna and the Indian hero Arjuna on human nature and the purpose of life

Hindooism. Hinduism - a body of religious and philosophical beliefs and cultural practices native to India and based on a caste system; it is characterized by a belief in reincarnation, by a belief in a supreme being of many forms and natures, by the view that opposing theories are aspects of one eternal truth, and by a desire for liberation from earthly evils

Mahabharata. Mahabharatam. Mahabharatum - (Hinduism) a sacred epic Sanskrit poem of India dealing in many episodes with the struggle between two rival families

Gita - (Hinduism) the sacred `song of God' composed about 200 BC and incorporated into the Mahabharata (a Sanskrit epic); contains a discussion between Krishna and the Indian hero Arjuna on human nature and the purpose of life

Hindooism. Hinduism - a body of religious and philosophical beliefs and cultural practices native to India and based on a caste system; it is characterized by a belief in reincarnation, by a belief in a supreme being of many forms and natures, by the view that opposing theories are aspects of one eternal truth, and by a desire for liberation from earthly evils

Mahabharata. Mahabharatam. Mahabharatum - (Hinduism) a sacred epic Sanskrit poem of India dealing in many episodes with the struggle between two rival families

Timolol - Fda Prescribing Information, Side Effects And Uses, Timonil

Timolol

Timolol Description

Timolol maleate is a nonselective beta-adrenergic receptor blocking agent. The chemical name for Timolol maleate is ( S ) - 1 - [(1,1 - dimethylethyl)amino] - 3 - [[4 - (4 - morpholinyl) - 1,2,5 - thiadiazol - 3 - yl]oxy] - 2 - propanol ( Z )-2-butenedioate (1:1) salt. It possesses an asymmetric carbon atom in its structure and is provided as the levo isomer. Its molecular formula is C 13 H 24 N 4 O 3 S•C 4 H 4 O 4 and its structural formula is:

Timolol maleate has a molecular weight of 432.50. It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol.

Timolol maleate is supplied as tablets containing 5 mg, 10 mg and 20 mg Timolol maleate for oral administration. Inactive ingredients are: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium lauryl sulfate, FD&C Blue #2 aluminum lake, and D&C Yellow #10 aluminum lake.

Timolol - Clinical Pharmacology

Timolol maleate is a beta 1 and beta 2 (nonselective) adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic activity.

Pharmacodynamics

Clinical pharmacology studies have confirmed the beta-adrenergic blocking activity as shown by (1) changes in resting heart rate and response of heart rate to changes in posture; (2) inhibition of isoproterenol-induced tachycardia; (3) alteration of the response to the Valsalva maneuver and amyl nitrite administration; and (4) reduction of heart rate and blood pressure changes on exercise.

Timolol decreases the positive chronotropic, positive inotropic, bronchodilator, and vasodilator responses caused by beta-adrenergic receptor agonists. The magnitude of this decreased response is proportional to the existing sympathetic tone and the concentration of Timolol at receptor sites.

In normal volunteers, the reduction in heart rate response to a standard exercise was dose dependent over the test range of 0.5 to 20 mg, with a peak reduction at 2 hours of approximately 30% at higher doses.

Beta-adrenergic receptor blockade reduces cardiac output in both healthy subjects and patients with heart disease. In patients with severe impairment of myocardial function beta-adrenergic receptor blockade may inhibit the stimulatory effect of the sympathetic nervous system necessary to maintain adequate cardiac function.

Beta-adrenergic receptor blockade in the bronchi and bronchioles results in increased airway resistance from unopposed parasympathetic activity. Such an effect in patients with asthma or other bronchospastic conditions is potentially dangerous.

Clinical studies indicate that Timolol maleate at a dosage of 20 to 60 mg/day reduces blood pressure without causing postural hypotension in most patients with essential hypertension. Administration of Timolol to patients with hypertension results initially in a decrease in cardiac output, little immediate change in blood pressure, and an increase in calculated peripheral resistance. With continued administration of Timolol, blood pressure decreases within a few days, cardiac output usually remains reduced, and peripheral resistance falls toward pretreatment levels. Plasma volume may decrease or remain unchanged during therapy with Timolol. In the majority of patients with hypertension Timolol also decreases plasma renin activity. Dosage adjustment to achieve optimal antihypertensive effect may require a few weeks. When therapy with Timolol is discontinued, the blood pressure tends to return to pretreatment levels gradually. In most patients the antihypertensive activity of Timolol is maintained with long-term therapy and is well tolerated.

The mechanism of the antihypertensive effects of beta-adrenergic receptor blocking agents is not established at this time. Possible mechanisms of action include reduction in cardiac output, reduction in plasma renin activity, and a central nervous system sympatholytic action.

A Norwegian multi-center, double-blind study, which included patients 20 to 75 years of age, compared the effects of Timolol maleate with placebo in 1,884 patients who had survived the acute phase of a myocardial infarction. Patients with systolic blood pressure below 100 mm Hg, sick sinus syndrome and contraindications to beta-blockers, including uncontrolled heart failure, second - or third-degree AV block and bradycardia (< 50 beats per minute), were excluded from the multi-center trial. Therapy with Timolol, begun 7 to 28 days following infarction, was shown to reduce overall mortality; this was primarily attributable to a reduction in cardiovascular mortality. Timolol significantly reduced the incidence of sudden deaths (deaths occurring without symptoms or within 24 hours of the onset of symptoms), including those occurring within one hour, and particularly instantaneous deaths (those occurring without preceding symptoms). The protective effect of Timolol was consistent regardless of age, sex or site of infarction. The effect was clearest in patients with a first infarction who were considered at a high risk of dying, defined as those with one or more of the following characteristics during the acute phase: transient left ventricular failure, cardiomegaly, newly appearing atrial fibrillation or flutter, systolic hypotension, or SGOT (ASAT) levels greater than four times the upper limit of normal. Therapy with Timolol also reduced the incidence of nonfatal reinfarction. The mechanism of the protective effect of Timolol is unknown.

Timolol was studied for the prophylactic treatment of migraine headache in placebo-controlled clinical trials involving 400 patients, mostly women between the ages of 18 and 66 years. Common migraine was the most frequent diagnosis. All patients had at least two headaches per month at baseline. Approximately 50 percent of patients who received Timolol had a reduction in the frequency of migraine headache of at least 50 percent, compared to a similar decrease in frequency in 30 percent of patients receiving placebo. The most common cardiovascular adverse effect was bradycardia (5%).

Pharmacokinetics and Metabolism

Timolol maleate is rapidly and nearly completely absorbed (about 90%) following oral ingestion. Detectable plasma levels of Timolol occur within one-half hour and peak plasma levels occur in about one to two hours. The drug half-life in plasma is approximately 4 hours and this is essentially unchanged in patients with moderate renal insufficiency. Timolol is partially metabolized by the liver and Timolol and its metabolites are excreted by the kidney. Timolol is not extensively bound to plasma proteins; i. e. < 10% by equilibrium dialysis and approximately 60% by ultrafiltration. An in vitro hemodialysis study, using 14 C Timolol added to human plasma or whole blood, showed that Timolol was readily dialyzed from these fluids; however, a study of patients with renal failure showed that Timolol did not dialyze readily. Plasma levels following oral administration are about half those following intravenous administration indicating approximately 50% first pass metabolism. The level of beta sympathetic activity varies widely among individuals, and no simple correlation exists between the dose or plasma level of Timolol maleate and its therapeutic activity. Therefore, objective clinical measurements such as reduction of heart rate and/or blood pressure should be used as guides in determining the optimal dosage for each patient.

Indications and Usage for Timolol

Hypertension

Timolol maleate tablets are indicated for the treatment of hypertension. They may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.

Myocardial Infarction

Timolol is indicated in patients who have survived the acute phase of myocardial infarction, and are clinically stable, to reduce cardiovascular mortality and the risk of reinfarction.

Migraine

Timolol is indicated for the prophylaxis of migraine headache.

Contraindications

Timolol maleate is contraindicated in patients with bronchial asthma or with a history of bronchial asthma, or severe chronic obstructive pulmonary disease (see WARNINGS ); sinus bradycardia; second - and third-degree atrioventricular block; overt cardiac failure (see WARNINGS ); cardiogenic shock; hypersensitivity to this product.

Warnings

Cardiac Failure

Sympathetic stimulation may be essential for support of the circulation in individuals with diminished myocardial contractility, and its inhibition by beta-adrenergic receptor blockade may precipitate more severe failure. Although beta-blockers should be avoided in overt congestive heart failure, they can be used, if necessary, with caution in patients with a history of failure who are well compensated, usually with digitalis and diuretics. Both digitalis and Timolol maleate slow AV conduction. If cardiac failure persists, therapy with Timolol maleate should be withdrawn.

In Patients Without a History of Cardiac Failure

Continued depression of the myocardium with beta-blocking agents over a period of time can, in some cases, lead to cardiac failure. At the first sign or symptom of cardiac failure, patients receiving Timolol should be digitalized and/or be given a diuretic, and the response observed closely. If cardiac failure continues, despite adequate digitalization and diuretic therapy, Timolol should be withdrawn.

Exacerbation of Ischemic Heart Disease Following Abrupt Withdrawal

Hypersensitivity to catecholamines has been observed in patients withdrawn from beta-blocker therapy; exacerbation of angina and, in some cases, myocardial infarction have occurred after abrupt discontinuation of such therapy. When discontinuing chronically administered Timolol maleate, particularly in patients with ischemic heart disease, the dosage should be gradually reduced over a period of one to two weeks and the patient should be carefully monitored. If angina markedly worsens or acute coronary insufficiency develops, Timolol maleate administration should be reinstituted promptly, at least temporarily, and other measures appropriate for the management of unstable angina should be taken. Patients should be warned against interruption or discontinuation of therapy without the physician's advice. Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue Timolol maleate therapy abruptly even in patients treated only for hypertension.

Obstructive Pulmonary Disease

PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (e. g. CHRONIC BRONCHITIS, EMPHYSEMA) OF MILD OR MODERATE SEVERITY, BRONCHOSPASTIC DISEASE OR A HISTORY OF BRONCHOSPASTIC DISEASE (OTHER THAN BRONCHIAL ASTHMA OR A HISTORY OF BRONCHIAL ASTHMA, IN WHICH ‘Timolol MALEATE’ IS CONTRAINDICATED, see CONTRAINDICATIONS ), SHOULD IN GENERAL NOT RECEIVE BETA-BLOCKERS, INCLUDING ‘Timolol’. However, if Timolol is necessary in such patients, then the drug should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta 2 receptors.

Major Surgery

The necessity or desirability of withdrawal of beta-blocking therapy prior to major surgery is controversial. Beta-adrenergic receptor blockade impairs the ability of the heart to respond to beta-adrenergically mediated reflex stimuli. This may augment the risk of general anesthesia in surgical procedures. Some patients receiving beta-adrenergic receptor blocking agents have been subject to protracted severe hypotension during anesthesia. Difficulty in restarting and maintaining the heartbeat has also been reported. For these reasons, in patients undergoing elective surgery, some authorities recommend gradual withdrawal of beta-adrenergic receptor blocking agents.

If necessary during surgery, the effects of beta-adrenergic blocking agents may be reversed by sufficient doses of such agonists as isoproterenol, dopamine, dobutamine or norepinephrine (see OVERDOSAGE ).

Diabetes Mellitus

Timolol should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. Beta-adrenergic receptor blocking agents may mask the signs and symptoms of acute hypoglycemia.

Thyrotoxicosis

Beta-adrenergic blockade may mask certain clinical signs (e. g. tachycardia) of hyperthyroidism. Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-blockade which might precipitate a thyroid storm.

Precautions

General

Impaired Hepatic or Renal Function

Since Timolol is partially metabolized in the liver and excreted mainly by the kidneys, dosage reductions may be necessary when hepatic and/or renal insufficiency is present.

Dosing in the Presence of Marked Renal Failure

Although the pharmacokinetics of Timolol are not greatly altered by renal impairment, marked hypotensive responses have been seen in patients with marked renal impairment undergoing dialysis after 20 mg doses. Dosing in such patients should therefore be especially cautious.

Beta-adrenergic blockade has been reported to potentiate muscle weakness consistent with certain myasthenic symptoms (e. g. diplopia, ptosis, and generalized weakness). Timolol has been reported rarely to increase muscle weakness in some patients with myasthenia gravis or myasthenic symptoms.

Because of potential effects of beta-adrenergic blocking agents relative to blood pressure and pulse, these agents should be used with caution in patients with cerebrovascular insufficiency. If signs or symptoms suggesting reduced cerebral blood flow are observed, consideration should be given to discontinuing these agents.

Drug Interactions

Close observation of the patient is recommended when Timolol is administered to patients receiving catecholamine-depleting drugs such as reserpine, because of possible additive effects and the production of hypotension and/or marked bradycardia, which may produce vertigo, syncope, or postural hypotension.

Non-Steroidal Anti-Inflammatory Drugs

Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by non-steroidal anti-inflammatory drugs has been reported. When using these agents concomitantly, patients should be observed carefully to confirm that the desired therapeutic effect has been obtained.

Literature reports suggest that oral calcium antagonists may be used in combination with beta-adrenergic blocking agents when heart function is normal, but should be avoided in patients with impaired cardiac function. Hypotension, AV conduction disturbances, and left ventricular failure have been reported in some patients receiving beta-adrenergic blocking agents when an oral calcium antagonist was added to the treatment regimen. Hypotension was more likely to occur if the calcium antagonist were a dihydropyridine derivative, e. g. nifedipine, while left ventricular failure and AV conduction disturbances were more likely to occur with either verapamil or diltiazem.

Intravenous calcium antagonists should be used with caution in patients receiving beta-adrenergic blocking agents.

Digitalis and Either Diltiazem or Verapamil

The concomitant use of beta-adrenergic blocking agents with digitalis and either diltiazem or verapamil may have additive effects in prolonging AV conduction time.

Potentiated systemic beta-blockade (e. g. decreased heart rate) has been reported during combined treatment with quinidine and Timolol, possibly because quinidine inhibits the metabolism of Timolol via the P-450 enzyme, CYP2D6.

Beta-adrenergic blocking agents may exacerbate the rebound hypertension which can follow the withdrawal of clonidine. If the two drugs are coadministered, the beta-adrenergic blocking agent should be withdrawn several days before the gradual withdrawal of clonidine. If replacing clonidine by beta-blocker therapy, the introduction of beta-adrenergic blocking agents should be delayed for several days after clonidine administration has stopped.

Risk of Anaphylactic Reaction

While taking beta-blockers, patients with a history of atopy or a history of severe anaphylactic reaction to a variety of allergens may be more reactive to repeated accidental, diagnostic, or therapeutic challenge with such allergens. Such patients may be unresponsive to the usual doses of epinephrine used to treat anaphylactic reactions.

Carcinogenesis, Mutagenesis, Impairment of Fertility

In a 2 year study of Timolol maleate in rats, there was a statistically significant increase in the incidence of adrenal pheochromocytomas in male rats administered 300 mg/kg/day (250 times1 the maximum recommended human dose). Similar differences were not observed in rats administered doses equivalent to approximately 20 or 80 times 1 the maximum recommended human dose.

In a lifetime study in mice, there were statistically significant increases in the incidence of benign and malignant pulmonary tumors, benign uterine polyps and mammary adenocarcinoma in female mice at 500 mg/kg/day (approximately 400 times 1 the maximum recommended human dose), but not at a 5 or 50 mg/kg/day. In a subsequent study in female mice, in which postmortem examinations were limited to uterus and lungs, a statistically significant increase in the incidence of pulmonary tumors was again observed at 500 mg/kg/day.

The increased occurrence of mammary adenocarcinoma was associated with elevations in serum prolactin that occurred in female mice administered Timolol maleate at 500 mg/kg/day, but not at doses of 5 or 50 mg/kg/day. An increased incidence of mammary adenocarcinomas in rodents has been associated with administration of several other therapeutic agents which elevate serum prolactin, but no correlation between serum prolactin levels and mammary tumors has been established in man. Furthermore, in adult human female subjects who received oral dosages of up to 60 mg of Timolol maleate, the maximum recommended daily human oral dosage, there were no clinically meaningful changes in serum prolactin.

Timolol maleate was devoid of mutagenic potential when elevated in vivo (mouse) in the micronucleus test and cytogenetic assay (doses up to 800 mg/kg) and in vitro in a neoplastic cell transformation assay (up to 100 mcg/mL). In Ames tests the highest concentrations of Timolol employed, 5,000 or 10,000 mcg/plate, were associated with statistically significant elevations of revertants observed with tester strain TA100 (in seven replicate assays), but not in three additional strains. In the assays with tester strain TA100, no consistent dose-response relationship was observed, nor did the ratio of test to control revertants reach 2. A ratio of 2 is usually considered the criterion for a positive Ames test.

Reproduction and fertility studies in rats showed no adverse effect on male or female fertility at doses up to 125 times 1 the maximum recommended human dose.

1 Based on patient weight of 50 kg.

Pregnancy

Pregnancy Category C

Teratogenicity studies with Timolol in mice, rats and rabbits at doses up to 50 mg/kg/day (approximately 40 times 1 the maximum recommended daily human dose) showed no evidence of fetal malformations. Although delayed fetal ossification was observed at this dose in rats, there were no adverse effects on postnatal development of offspring. Doses of 1000 mg/kg/day (approximately 830 times 1 the maximum recommended daily human dose) were maternotoxic in mice and resulted in an increased number of fetal resorptions. Increased fetal resorptions were also seen in rabbits at doses of approximately 40 times 1 the maximum recommended daily human dose, in this case without apparent maternotoxicity. There are no adequate and well controlled studies in pregnant women. Timolol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Nursing Mothers

Timolol maleate has been detected in human milk.

Because of the potential for serious adverse reactions from Timolol in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

Geriatric Use

Clinical studies of Timolol for the treatment of hypertension or migraine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.

In a clinical study of Timolol in patients who had survived the acute phase of a myocardial infarction, approximately 350 patients (37%) were 65 to 75 years of age. Safety and efficacy were not different between these patients and younger patients (see CLINICAL PHARMACOLOGY: Pharmacodynamics ).

Other reported clinical experience has not identified differences in response between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.

This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. (See PRECAUTIONS: Impaired Hepatic or Renal Function and Dosing in the Presence of Marked Renal Failure .)

The results from 5 single - and/or multiple-dose PK studies comparing the impact of age on the PK of hydrochlorothiazide, when given in combination with other antihypertensive drugs, were consistent. They indicated a mean median increase in C max and AUC of 38% and 99% respectively, in elderly relative to younger subjects.

Adverse Reactions

Timolol maleate tablets are usually well tolerated in properly selected patients. Most adverse effects have been mild and transient.

In a multi-center (12 week) clinical trial comparing Timolol maleate and placebo in hypertensive patients, the following adverse reactions were reported spontaneously and considered to be causally related to Timolol maleate:

The following additional adverse effects have been reported in clinical experience with the drug: Body as a Whole: anaphylaxis, extremity pain, decreased exercise tolerance, weight loss, fever; Cardiovascular: cardiac arrest, cardiac failure, cerebral vascular accident, worsening of angina pectoris, worsening of arterial insufficiency, Raynaud's phenomenon, palpitations, vasodilatation; Digestive: gastrointestinal pain, hepatomegaly, vomiting, diarrhea, dyspepsia; Hematologic: nonthrombocytopenic purpura; Endocrine: hyperglycemia, hypoglycemia; Skin: rash, skin irritation, increased pigmentation, sweating, alopecia; Musculoskeletal: arthralgia; Nervous System: local weakness, increase in signs and symptoms of myasthenia gravis; Psychiatric: depression, nightmares, somnolence, insomnia, nervousness, diminished concentration, hallucinations; Respiratory: cough; Special Senses: visual disturbances, diplopia, ptosis, dry eyes; Urogenital: impotence, urination difficulties.

There have been reports of retroperitoneal fibrosis in patients receiving Timolol maleate and in patients receiving other beta-adrenergic blocking agents. A causal relationship between this condition and therapy with beta-adrenergic blocking agents has not been established.

Potential Adverse Effects

In addition, a variety of adverse effects not observed in clinical trials with Timolol maleate, but reported with other beta-adrenergic blocking agents, should be considered potential adverse effects of Timolol. Nervous System: Reversible mental depression progressing to catatonia; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics; Cardiovascular: Intensification of AV block (see CONTRAINDICATIONS ); Digestive: Mesenteric arterial thrombosis, ischemic colitis; Hematologic: Agranulocytosis, thrombocytopenic purpura; Allergic: Erythematous rash, fever combined with aching and sore throat, laryngospasm with respiratory distress; Miscellaneous: Peyronie's disease.

There have been reports of a syndrome comprising psoriasiform skin rash, conjunctivitis sicca, otitis, and sclerosing serositis attributed to the beta-adrenergic receptor blocking agent, practolol. This syndrome has not been reported with Timolol.

Clinical Laboratory Test Findings

Clinically important changes in standard laboratory parameters were rarely associated with the administration of Timolol. Slight increases in blood urea nitrogen, serum potassium, uric acid, and triglycerides, and slight decreases in hemoglobin, hematocrit and HDL cholesterol occurred, but were not progressive or associated with clinical manifestations. Increases in liver function tests have been reported.

Overdosage

Overdosage has been reported with Timolol maleate tablets. A 30 year old female ingested 650 mg of Timolol maleate (maximum recommended daily dose - 60 mg) and experienced second - and third-degree heart block. She recovered without treatment but approximately 2 months later developed irregular heart beat, hypertension, dizziness, tinnitus, faintness, increased pulse rate and borderline first degree heart block.

The oral LD 50 of the drug is 1190 and 900 mg/kg in female mice and female rats, respectively.

An in vitro hemodialysis study, using 14 C Timolol added to human plasma or whole blood, showed that Timolol was readily dialyzed from these fluids; however, a study of patients with renal failure showed that Timolol did not dialyze readily.

The most common signs and symptoms to be expected with overdosage with a beta-adrenergic receptor blocking agent are symptomatic bradycardia, hypotension, bronchospasm, and acute cardiac failure. Therapy with Timolol should be discontinued and the patient observed closely. The following additional therapeutic measures should be considered:

• (1) Gastric lavage. • (2) Symptomatic bradycardia: Use atropine sulfate intravenously in a dosage of 0.25 mg to 2 mg to induce vagal blockade. If bradycardia persists, intravenous isoproterenol hydrochloride should be administered cautiously. In refractory cases the use of a transvenous cardiac pacemaker may be considered. • (3) Hypotension: Use sympathomimetic pressor drug therapy, such as dopamine, dobutamine or norepinephrine. In refractory cases the use of glucagon hydrochloride has been reported to be useful. • (4) Bronchospasm: Use isoproterenol hydrochloride. Additional therapy with aminophylline may be considered. • (5) Acute cardiac failure: Conventional therapy with digitalis, diuretics, and oxygen should be instituted immediately. In refractory cases the use of intravenous aminophylline is suggested. This may be followed if necessary by glucagon hydrochloride which has been reported to be useful. • (6) Heart block (second - or third-degree): Use isoproterenol hydrochloride or a transvenous cardiac pacemaker.

Timolol Dosage and Administration

Hypertension

The usual initial dosage of Timolol maleate is 10 mg twice a day, whether used alone or added to diuretic therapy. Dosage may be increased or decreased depending on heart rate and blood pressure response. The usual total maintenance dosage is 20 to 40 mg per day. Increases in dosage to a maximum of 60 mg per day divided into two doses may be necessary. There should be an interval of at least 7 days between increases in dosages.

Timolol maleate tablets may be used with a thiazide diuretic or with other antihypertensive agents. Patients should be observed carefully during initiation of such concomitant therapy.

Myocardial Infarction

The recommended dosage for long-term prophylactic use in patients who have survived the acute phase of a myocardial infarction is 10 mg given twice daily (see CLINICAL PHARMACOLOGY ).

Migraine

The usual initial dosage of Timolol maleate is 10 mg twice a day. During maintenance therapy the 20 mg daily dosage may be administered as a single dose. Total daily dosage may be increased to a maximum of 30 mg, given in divided doses, or decreased to 10 mg once per day, depending on clinical response and tolerability. If a satisfactory response is not obtained after 6 to 8 weeks use of the maximum daily dosage, therapy with Timolol should be discontinued.

How is Timolol Supplied

Timolol Maleate Tablets, USP are available containing 5 mg, 10 mg and 20 mg of Timolol maleate, USP.

The 5 mg tablets are green, unscored, flat-faced round tablets debossed with M over 55 on one side of the tablet and blank on the other side. They are available as follows:

NDC 0378-0055-01 bottles of 100 tablets

The 10 mg tablets are green, scored, flat-faced round tablets debossed with M above the score and 221 below the score on one side of the tablet and blank on the other side. They are available as follows:

NDC 0378-0221-01 bottles of 100 tablets

The 20 mg tablets are green, scored, capsule-shaped tablets debossed with M to the left of the score and 715 to the right of the score on one side of the tablet and blank on the other side. They are available as follows:

NDC 0378-0715-01 bottles of 100 tablets

Store at 20° to 25°C (68° to 77°F). [See USP for Controlled Room Temperature.]

Protect from light.

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505

REVISED AUGUST 2006

PRINCIPAL DISPLAY PANEL - 5 mg

Timolol Maleate Tablets, USP 5 mg

Rx only 100 Tablets

Each tablet contains: Timolol maleate, USP 5 mg

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Keep this and all medication out of the reach of children.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Protect from light.

Usual Adult Dosage: See accom - panying prescribing information.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505 U. S.A.

PRINCIPAL DISPLAY PANEL - 10 mg

Timolol Maleate Tablets, USP 10 mg

Rx only 100 Tablets

Each tablet contains: Timolol maleate, USP 10 mg

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Keep this and all medication out of the reach of children.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Protect from light.

Usual Adult Dosage: See accom - panying prescribing information.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505 U. S.A.

PRINCIPAL DISPLAY PANEL - 20 mg

Timolol Maleate Tablets, USP 20 mg

Rx only 100 Tablets

Each tablet contains: Timolol maleate, USP 20 mg

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Keep this and all medication out of the reach of children.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Protect from light.

Usual Adult Dosage: See accom - panying prescribing information.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505 U. S.A.

Kefcin 375mg (Cefaclor) - Rx Vietnam, Kefcin

Product Description

MÔ T? Kháng sinh nhóm cephalosporin CÔNG TH?C: Cefaclor. 375 mg Tá du?c v?a d?. 1 viên (Sodium starch glycolate, tinh b?t mì, aerosil, natri lauryl sulfat, ludipress, b?t talc, sepifilm, m àu indogo lake, màu blue lake). D?NGBÀOCH?: viên nén bao phim. QUY CÁCH DÓNG GÓI: H?p 2 v? x 5 viên. TÍNH CH?T: Kefcin, v?i thành ph?n chính là cefaclor, là kháng sinh nhóm cephalosporin bán t?ng h?p th? h? 2, có tác d?ng di?t vi khu?n do ?c ch? quá trình t?ng h?p thành t? bào vi khu?n. Ph? kháng khu?n c?a cefaclor bao g?m: vi khu?n hi?u khí Gram duong: Staphylococcus, Streptococcus pneumonia, Streptococcus pyogenes; vi khu?n hi?u khí Gram âm: Moraxella catarrhalis, Haemophilus influenzae, Escherichia coli, Proteus mirabilis, Klebsiella spp. Citrobacter diversus, Nesseria gonorrhoeae; vi khu?n k? khí: Bacteriodes spp. (ngo?i tr? Bacteriodes fragilis), Peptococcus spp. Peptostreptococcus spp. Propionibacterium acnes. Cefaclor du?c h?p thu r?t t?t sau khi u?ng lúc dói. Th?c an làm ch?m h?p thu, nhung t?ng lu?ng thu?c du?c h?p thu v?n không d?i. Kho?ng 25% cefaclor g?n k?t v?i protein huy?t tuong. Cefaclor phân b? r?ng kh?p co th?, di qua nhau thai, bài ti?t trong s?a m? ? n?ng d? th?p và th?i tr? qua th?n.

Di?u tr? nhi?m khu?n du?ng hô h?p: viêm h?ng, viêm amidan, viêm ph? qu?n, viêm ph?i, viêm xoang, viêm tai gi?a; nhi?m khu?n du?ng ti?t ni?u: viêm bàng quang, viêm ni?u d?o do l?u c?u; nhi?m khu?n da và mô m?m.

M?n c?m v?i kháng sinh nhóm cephalosporin.

Có ti?n s? d? ?ng v?i penicilin. Suy th?n n?ng.

Có ti?n s? b?nh du?ng tiêu hoá nhu viêm d?i tràng.

Ph? n? có thai và cho con bú. Tr? em du?i 1 tháng tu?i.

Probenecid làm tang n?ng d? cefaclor trong huy?t thanh. Dùng d?ng th?i cefaclor v?i các thu?c kháng sinh aminoglycosid ho?c thu?c l?i ti?u furosemid làm tang d?c tính d?i v?i th?n.

TÁC D?NG KHÔNG MONG MU?N:

D? ?ng: nhu ng?a, phát ban, n?i m? day. Bu?n nôn, nôn, tiêu ch?y. R?i lo?n công th?c máu (gi?m ti?u c?u, tang b?ch c?u ái toan).

Thông báo cho bác si nh?ng tác d?ng không mong mu?n g?p ph?i khi s? d?ng thu?c.

Ngu?i l?n: u?ng 1 viên ´ 2 -3 l?n / ngày.

Ho?c theo ch? d?n c?a Th?y thu?c.

D?c k? hu?ng d?n s? d?ng tru?c khi dùng.

N?u c?n thêm thông tin, xin h?i ý ki?n bác si.

Thu?c này ch? dùng theo s? kê don c?a Th?y thu?c.

24 tháng k? t? ngày s?n xu?t.

Noi khô mát, tránh ánh sáng.

DESCRIPTION Cephalosporin Antibiotics COMPOSITION Cefaclor. 375 mg Excipients q. s. 1 sachet (Saccharose, strawberry flavor, sodium lauryl sulphate, methylcellulose, erythrosine color, propylene glycol). DOSAGE FORM Powder PRESENTATION Box of 25 sachets x 3 g powder. ACTIONS INDICATIONS Treatment of upper and lower respiratory tract infections (pharyngitis, tonsillitis, bronchitis, pneumonia), sinusitis, otitis media, skin and soft tissue infections, urinary tract infections. CONTRAINDICATIONS Hypersensitivity to Cephalosporins and Penicillin. PRECAUTIONS Severe renal impairment, impaired hepatic function. History of gastrointestinal tract diseases such as colitis. Pregnant women and breast-feeding mothers. Infants under 1 month of age. INTERACTIONS Renal excretion of Cefaclor is inhibited by Probenecid. Antacids containing magnesium or aluminium decrease the effect of Cefaclor. ADVERSE EFFECTS Allergic manifestations e. g pruritus, rashes, urticaria. Rarely: Stevens-Johnson syndrome, epidermal necrosis, and anaphylactic reactions. Pseudomembranous colitis (that will be recovered after a discontinuance of drug). Rarely: nausea, vomiting, diarrhoea, mild hepatitis, and cholestatic jaundice. Hematological disturbances (thrombocytopenia, acidophilic leukocytosis). Inform your physician about any adverse effects occur during the treatment. DOSAGE & ADMINISTRATION Children: Usual doses: 20 mg / kg body-weight / day, every 8 hours. Maximum dose: 1 g daily. In case of bronchitis and pneumonia: 20 mg / kg body-weight / day, in 3 divided doses. Concretely as follows: Children 9 kg body-weight: oral dose of ½ sachet x 3 times daily. Children 18 kg body-weight: oral dose of 1 sachet x 3 times daily. In case of more severe infections, otitis media, or infections caused by less susceptible bacteria, the dose should be given 40 mg / kg body-weight / day, in many divided doses. Concretely as follows: Children 9 kg body-weight: oral dose of 1 sachet x 3 times daily. Children 18 kg body-weight: oral dose of 2 sachets x 3 times daily. Or as directed by the physician. Read the directions carefully before use. Consult the physician for more information. This drug is for prescriptions o­nly. SHELF-LIFE 24 months from the manufacturing date. STORAGE CONDITIONS Store in cool, dry place; protected from light. SPECIFICATIONS Manufacturer's.

COMPOSITION Cefaclor. 125 mg Excipients q. s. 1 sachet (Saccharose, strawberry flavor, sodium lauryl sulphate, methylcellulose, erythrosine color, propylene glycol). DOSAGE FORM Powder PRESENTATION Box of 25 sachets x 3 g powder. ACTIONS INDICATIONS Treatment of upper and lower respiratory tract infections (pharyngitis, tonsillitis, bronchitis, pneumonia), sinusitis, otitis media, skin and soft tissue infections, urinary tract infections. CONTRAINDICATIONS Hypersensitivity to Cephalosporins and Penicillin. PRECAUTIONS Severe renal impairment, impaired hepatic function. History of gastrointestinal tract diseases such as colitis. Pregnant women and breast-feeding mothers. Infants under 1 month of age. INTERACTIONS Renal excretion of Cefaclor is inhibited by Probenecid. Antacids containing magnesium or aluminium decrease the effect of Cefaclor. ADVERSE EFFECTS Allergic manifestations e. g pruritus, rashes, urticaria. Rarely: Stevens-Johnson syndrome, epidermal necrosis, and anaphylactic reactions. Pseudomembranous colitis (that will be recovered after a discontinuance of drug). Rarely: nausea, vomiting, diarrhoea, mild hepatitis, and cholestatic jaundice. Hematological disturbances (thrombocytopenia, acidophilic leukocytosis). Inform your physician about any adverse effects occur during the treatment. DOSAGE & ADMINISTRATION Children: Usual doses: 20 mg / kg body-weight / day, every 8 hours. Maximum dose: 1 g daily. In case of bronchitis and pneumonia: 20 mg / kg body-weight / day, in 3 divided doses. Concretely as follows: Children 9 kg body-weight: oral dose of ½ sachet x 3 times daily. Children 18 kg body-weight: oral dose of 1 sachet x 3 times daily. In case of more severe infections, otitis media, or infections caused by less susceptible bacteria, the dose should be given 40 mg / kg body-weight / day, in many divided doses. Concretely as follows: Children 9 kg body-weight: oral dose of 1 sachet x 3 times daily. Children 18 kg body-weight: oral dose of 2 sachets x 3 times daily. Or as directed by the physician. Read the directions carefully before use. Consult the physician for more information. This drug is for prescriptions o­nly. SHELF-LIFE 24 months from the manufacturing date. STORAGE CONDITIONS Store in cool, dry place; protected from light. SPECIFICATIONS Manufacturer's.

Find Similar Products by Category

Primaquine (Phosphate Tablets) Side Effects, Interactions, Warning, Dosage & Uses, Primaquin

DRUG DESCRIPTION

Primaquine phosphate is 8-[(4-Amino-1-methylbutyl) amino]-6-methoxyquinoline phosphate, a synthetic compound with potent antimalarial activity. Each tablet contains 26.3 mg of primaquine phosphate (equivalent to 15 mg of primaquine base). The dosage is customarily expressed in terms of the base.

Inactive Ingredients

Carnauba Wax, Hydroxypropyl Methylcellulose, Lactose, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol 400, Polysorbate 80, Pregelatinized Starch, Red Ferric Oxide, Talc, Titanium Dioxide.

What are the possible side effects of primaquine ()?

Stop taking primaquine and seek emergency medical attention if you experience an allergic reaction (flushing; swelling of your lips, tongue, or face, difficulty breathing; closing of your throat; vision problems; a rash; or itching).

Notify your doctor if you experience darkening of your urine.

Nausea, stomach pain or upset, vomiting, and loss of appetite may also occur during therapy.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at.

What are the precautions when taking phosphate tablets (Primaquine)?

Before taking primaquine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system disease (such as lupus, rheumatoid arthritis), blood problems (such as low white blood cell counts, anemia), history of blood problems due to primaquine (such as hemolytic anemia, methemoglobinemia), personal/family history of favism, low levels of certain blood enzymes (glucose-6-phosphate dehydrogenase-G6PD, NADH methemoglobin reductase).

Your doctor may order a blood test to see if you have any enzyme.

Last reviewed on RxList: 8/5/2016 This monograph has been modified to include the generic and brand name in many instances.

Andropel, Andropel

Andropel

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Was this page helpful?

Androgel and weight gain

androgel

Exercise has been known to increase testosterone levels naturally. The back pain could be due to decreased calcium levels or weight gain. You will need to increase intake of calcium-rich foods so as to have a daily intake of calcium between 500-1000 mg. Insulin has been reported to interact with T from androgel, so discuss this with your physician if you are diabetic. Oral zinc has also been reported to increase testosterone production.

I realize I look a bit gaunt when my weight is lower than this, but I could not gain weight until my tract healed. People are just jealous I suppose. I can eat 2000 calories a day just to maintain. Not my fault. It's hard to do when you can't eat gluten.

It is 4am and i cant sleep because all this weight gain consumes me. I am so miserable and i need HELP. This protocol feels like a heaven sent or the last result, lol. I appreciate all of you who are sharing your experiences and references. This really helps in making a wise decision.

I have been suffering for about 3 or even more years for fatigue, slow, poor, brittle hair and nails growth, fluid retention, weight gain. yo yo diet, and most important, my vision is getting worsen from year to year! AND my cold feet became ICY COLD TOES / feet. So, i decided to go on self-paid thyroid test. Endo said from results that i have only Testosterone deficiency - SECONDARY HYPOGONADISM. And.

I had consistent GI issues for about 4 months prior to starting Androgel - with the result I lost a lot of weight and am now very thin. I've gotten mixed messages on this query - from "No it makes no difference" to "Yes - low T affects your entire body.

I have been suffering for about 3 or even more years for fatigue, slow, poor, brittle hair and nails growth, fluid retention, weight gain. yo yo diet, and most important, my vision is getting worsen from year to year! AND my cold feet became ICY COLD TOES / feet. So, i decided to go on self-paid thyroid test. Endo said from results that i have only Testosterone deficiency - SECONDARY HYPOGONADISM. And.

. depression), dizziness, breast pain or enlargement, weight gain. change in size or shape of the testicles etc. Get a ultrasound abdomen with ECG done. I would suggest that you get a work up done for elevated levels of SGOT, by your physician and rule out the causes for the same. Best.

the shots because the shots are much stronger. Did you have much weight gain on the shots, and high of testosterone level did you get to. Why are you now switching to the patch. I think you would do better if you are comming off the shots to go to androgel than the patch.

The downside risks appear to be modest, and include weight gain. sleep apnea, and an increased red blood cell count. There is also much concern about long-term effects on the prostate, including an acceleration of benign enlargement or an increased risk of prostate cancer. Those with higher levels of testosterone are more inclined to smoke, drink alcohol excessively and indulge in risky behavior that leads to injury.

I am currently on 88mcg of Synthroid and 10 mcg of Cytomel. My symptoms of fatigue, hair loss, weight gain (more fat than weight ), tinnitus, and muscle cramps are still with me. I am just over 5'9" and weigh 170.

Within the last 6 weeks I have experienced severe weakness (CPK at 1200), unusual weight gain. enlarged and painful breasts, fatigue worse than usual. My GP ordered labs which included: CMP, TSH, Testosterone total, LH, CK total. He called Saturday primarily concerned with Testosterone level of 23. I have history of volatile TSH, cortisol and low potassium levels. I currently take 40 meq? of potassium a day and prescribed Androgel 1.

fatigue, depression at times, extremeties that easily lose circulation, very cold and very dry hands in winter, salt cravings, joint pain, significant weight gain in abdominal region despite diet and exercise. Currently work in South Korea, treated by Korean MDs. Recent results: T3 normal, TSH 1.26 normal (range 0.4 - 4.1), T4 normal 6.2, Free T4 low 0.59 (range 0.70 - 1.80). Also: Prolactin (normal), GH (normal), FSH (low), LH (low), Cortisol (afternoon draw) low 4.

I am 55, soon to be 56. I noticed an incredible weight gain when I worked for a year and a half from 53-55. Then I stopped working earlier this year, did the low-carb thing for four months and started working out again. Lo and behold, my figure came back! I would trade being slender any day of the week for somewhat crepy skin. But that is our nemesis. I don't have money to spend on beauty products, nor on many supplements. So my routine is so basic it's ridiculous.

Depression can cause testosterone to drop and so can weight gain. In Australia Testogel costs about $90 a month but when prescribed on the pharmacy benefits scheme only costs the consumer about $32.

Went to the ER, they sent me home with Xanax. I won't take it. Then my doc tried to get me to take androgel (t gel), and about 20 minutes after I used the gel, I had another panic attack. I can't figure it out. its not like I am thinking anything in particular. just minding my own business, then a strange feeling comes over me and I can't breath. heart starts pounding. WTH. And my Serum T level is at 185.

Again, it is very strange that I would experience hair loss on my face, eyebrow, head, gain weight. lose sex drive, experience extreme fatigue, and facial flushing all at the same time. Lastly, the dermatologist thought it was odd that my eyebrow hair falls out and re-grows weekly. He normally sees a complete re-growth or no re-growth at all. It seems when I use my over the counter inhauler (contains epinephrine) my flushing gos away.

I never had this additional head congestion issue until I started with the blood pressure/Androgel meds. Could you please give me your comments on this and any suggestions for relief. Thank you. Merf.

Every time I see my endo I constantly complain of many side effects. These effects include fatigue, weakness, WEIGHT GAIN of about 40 pounds, decreased sex drive, depression, and some memory loss. Also, blood tests reveal a trigylceride level of 557 with no family history of high trigylceride and I eat a healthy diet and exercise regularly. I was wondering if anyone had any useful information for me so I could finally feel "normal" again!

Just this past week I gained 6 pounds Constipation I'm a 27 y/o male that is generally healthy. My mental state is great even though I have these symptoms. They can't pawn it off on depression. I just received a fax of my bloodwork. It was a CBC (which all is fine) and just a TSH test on my thyroids. It came back as 2.1 and the range is .45 - 4.5. I fall under "normal". Now I know from reading here I need to get my free T3 and free T4 checked.

They are considered safe, but no long term studies have been done yet though the short studies all look good though they do increase your dht levels as well as the testosterone so many people notice side effects like balding, enlarged pituatary gland, and acne so unless you are working out and trying to gain muscle mass, you should probably just try the zinc test.

I have been taking the Androgel for 3 weeks now and still haven't seen any improvement down there. I also still have a little excess belly fat that I never used to have (I work out alot and have always been skinier than most people). I also noticed that if I consume alcohol (even just a beer) it exascerbates the symptoms. Do you think the gel just isn't working? Or is it that I have too much estrogen? I'm scheduled to see another urologist in two weeks. Any suggestions. Again, thanks alot.

I mean absolutely no energy even when his mind has plenty of energy. Sometimes he wants to do things and just can't. - weight gain.

The oral medication cured that and the mood swings disappeared. I was on Androgel for a time, but there is a caveat about that. Being a topical testosterone it can rub off on your wife while being intimate and cause her problems. I know of one woman who was so affected. Perhaps a consultation with your husband's urologist would be in order. We had to work with mine for a time to find what was right for me.

i allready know that i have hypogonadism and was on androgel for about 10 months but did not fix my ed and started to cause testicular atropey im hopeing that if i go back on the trt that i will be useing hcg or something to keep the testis working. hopeing if any of you could think of any more test that i should ask for (will be getting the basic blood test to) tird of the urigist hopeing endo will know more. i have been off of the androgel for about 3 months. ill get to see where im at.

I know it is the same as candy bars but it makes me feel a little better if I can fool myself into thinking it may be good for me. Because of the weight gain my high blood pressur returned. I have constapation that requires me to take laxitives, try to use the fiber ones. After taking the meds for several years I had a big drop in my testastrone levels, I now take androgel to get the levels back up. Not to mention the reduced sex drive. so I wont mention it. My skin has changed.

If I have an appt to attend I have to get up 4 hrs prior just to get myself able to shower n dress. Ive gained back 60# of the 25# I lost during g tx even tho I barely eat. The weight gain just keeps coming. My hair that fell out grew back a little but now is falling out again. I have muscle aches and joint pain so bad sometimes I can't move and feel like I'm 95 I'm only 46.

and like most teenagers i love sports, staying active and weight lifting. 5 months without doing anything realy *****. and now i have usual pain along the surgical area and inside part of my leg and groin is this normal? i dont have any testicular pain what so ever. and i dont realy know when to start weight lifting and playing sports again itss been harrasing me for all this time. how do u know when to start again. can i start even though i feel a little bit of pain?

I go to gym for run and mild weight lift. I do yoga, without crunching my abdomen much. By experimenting a little, I found that the pain is not related to these activities. But, sometimes I apply warm towel to left lower abdomen (not to the balls!) and it seems to help. Anyone can try this and see if it works. And experiment with your physical activities to see if there are any agravating factor in them. If not, keep yourself physically active, it helps a lot.

During the time of the pain I've gone from extremely out of shape, to fairly fit, and back again. No changes. No major weight changes either. Has anyone tired massage yet? Sounds like I don't need to bother with sleeping pills, and better if I don't.

Atensina, Atensina

Neurontin is used for treating seizures associated with epilepsy. Neurontin is an anticonvulsant.

Use Neurontin as directed by your doctor.

Take Neurontin by mouth with or without food.

Do not take an antacid containing aluminum or magnesium within 2 hours before you take Neurontin.

If you are taking half of a scored tablet as your dose, take the other half of that tablet as your next dose. Throw away any half-tablets not used within several days of breaking a scored tablet.

Do not suddenly stop taking Neurontin. You may have an increased risk of side effects (eg, seizures). If you need to stop Neurontin or add a new medicine, your doctor will gradually lower your dose.

If you miss a dose of Neurontin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Neurontin.

Store Neurontin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Neurontin out of the reach of children and away from pets.

Active Ingredient: Gabapentin.

Do NOT use Neurontin if:

you are allergic to any ingredient in Neurontin.

Some medical conditions may interact with Neurontin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have kidney problems and are on dialysis

if you have a history of mental or mood problems (eg, depression), or suicidal thoughts or actions.

Some medicines may interact with Neurontin. Tell your health care provider if you are taking any medicines, especially any of the following:

Morphine because it may increase the risk of Neurontin's side effects, including drowsiness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Neurontin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Neurontin may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Neurontin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Patients who take Neurontin may be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take Neurontin closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.

Diabetes patients - Neurontin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Neurontin may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Neurontin.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Neurontin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Neurontin with caution in the elderly; they may be more sensitive to its effects.

Neurontin may cause emotional or behavioral side effects in children 3 to 12 years. If the following side effects occur, notify your doctor immediately: emotional "swings", hostile or aggressive behavior, problems concentrating, decreased performance at school, an increase in restlessness or hyperactivity.

Neurontin should be used with extreme caution in children younger 3 years; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Neurontin while you are pregnant. Neurontin is found in breast milk. If you are or will be breast-feeding while you use Neurontin, check with your doctor. Discuss any possible risks to your baby.

If you stop taking Neurontin suddenly, you may have withdrawal symptoms. These may include dizziness, drowsiness, clumsiness, hostility, hyperactivity, mood swings, nausea, tiredness, or vomiting.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Back pain; changes in vision (double or blurred vision); clumsiness; constipation; diarrhea; dizziness; drowsiness; dry mouth; nausea; stomach upset; tiredness; vomiting; weight gain.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal thoughts; back and forth eye movements; behavioral problems; change in school performance; chest pain; confusion; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hyperactivity; loss of coordination; memory loss; new or worsening mental or mood changes (eg, depression, agitation, anxiety, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, inability to sit still); new or worsening seizures; numbness of an arm or leg; one-sided weakness; severe headache or dizziness; shortness of breath; speech changes; suicidal thoughts or actions; swelling of the hands, legs, or feet; tremor; trouble concentrating; twitching.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Joseph Losack - Wharton Journal-Spectator Obituaries, Flozak

Joseph Losack

Posted: Saturday, December 13, 2014 6:30 am

Joseph Patrick “Joe” Losack, age 80, of Wharton, died Monday, Dec. 8, 2014. Joe was born on March 21, 1934 in Orchard, son of the late John Martin and Martha Lisiecki Losack.

Joe was reared in the East Bernard area and graduated from East Bernard High School. He played football at Wharton County Junior College and University of Texas where he received his bachelor’s degree. He served in the U. S. Marine Corps for five years. Joe met the love of his life, Linda Faye Cale, at Camp Lejeune, N. C. where he was stationed in 1962. They married in Wilson, N. C. on Jan. 26, 1963.

kA 4=2DDlQAaQmkDA2? 4=2DDlQD`Qmy@6 2?5

=:G:2[ p56=J?[ yF=6D[

kA 4=2DDlQAaQmkDA2? 4=2DDlQD`Qm! C6465:?8 9:>. 562E9 H6C6 9:D A2C6?EDj 3C@E96CD[ y@9. 6[ %9@>2D[

kA 4=2DDlQAaQmkDA2? 4=2DDlQD`Qm':8:= H2D 96=5 7C@> d E@ f A]>] 7@==@H65 3J 2 C@D2CJ @? %9FCD52J[ s64] ``[ 2E vF2C5:2? p?86= r2E9@=:4 r9FC49. (2==:D] uF?6C2= D6CG:46D H6C6 96=5 2E a A]>] uC:52J[ s64] `a[ 2E vF2C5:2? p?86= r2E9@=:4 r9FC49] |2DD @77:4:2E6D H6C6 #6G] %9FJ >8FJ6? 2?5 s624@? v6C@>6

kA 4=2DDlQAaQmkDA2? 4=2DDlQD`QmuF?6C2= D6CG:46D H6C6 F?56C E96 5:C64E:@? @7 z?6D6< uF?6C2= w@>6. (2==:D]k^DA2?mk^Am

Senaglinide, Senaglinide

Nateglinide

D-Phenylalanine, N-((4-(1-metyletyl)cyclohexyl)carbonyl)-, trans -

Foreign Names

Generic Names

Nateglinide (OS: USAN, BAN, JAN)

Nateglinide (OS: DCF)

A 4166 (IS)

AY 4166 (IS: Ajinomoto)

DJN 608 (IS)

Meglitinide (IS)

SDZ DJN 608 (IS: Sandoz)

Senaglinide (IS)

YM 026 (IS: Yamanouchi)

Nataglinide (PH: Ph. Eur. 8)

Nateglinid (PH: Ph. Eur. 8)

Nateglinide (PH: BP 2016, JP XVI, USP 38)

Nateglinide (PH: Ph. Eur. 8)

Nateglinidum (PH: Ph. Eur. 8)

Brand Names

Antangping The United Laboratories Ltd, China

Bei Jia Chia Tai Tianqing, China

Cankexin HuaXia Pharm Group, China

Changtai Xingan Pharmaceutical, China

Danping (pediatric) Wuhan, China

Di Fang Topfond Pharmaceutical, China

Fastic Ajinomoto Seiyaku, Japan

Fei Ge Na Qilu, China

Fu Ge Qing Hailing, China

Glinate Glenmark, India

Glinate-MF (Nateglinide and Metformin) Glenmark, India

Glunat U. C. Pharma, Taiwan

Incuria Sanovel, Turkey

Inglex Deva, Turkey

Kai Shu Jiacheng Medical Treatment Apparatus, China

Ke Bin Zhaohui, China

La Mu Southwest, China

Luoyu Luoxin Pharmacy, China

Naglid Abdi Ibrahim, Turkey

Natefine NeoCarDiabCare, India

Nateglinide Actavis Actavis, United States

Nateglinide Mylan Mylan Seiyaku, Japan

Nateglinide Nichi-Iko Nichi-Iko Pharmaceutical, Japan

Nateglinide Par Par Pharmaceutical, Inc. United States

Nateglinide Teva Taisho Yakuhin, Japan

Natenide Standard, Taiwan

Nds Emcure, India

Netcose Chen Ho, Taiwan

Nopik Square, Bangladesh

Qi Fu Hailing, China; Yangtze River Pharma, China

Roxiton Washington, Taiwan

Starform (Nateglinide and Metformin) Novartis, Brazil

Starlidine Idi, Egypt

Starlix Grupo Novartis, Spain; Novartis, Argentina; Novartis, Bangladesh; Novartis, Brazil; Novartis, Chile; Novartis, China; Novartis, Egypt; Novartis, Croatia (Hrvatska); Novartis, Hungary; Novartis, Indonesia; Novartis, Lithuania; Novartis, Oman; Novartis, Poland; Novartis, Portugal; Novartis, Sweden; Novartis, Turkey; Novartis, Taiwan; Novartis, United States; Novartis AH, South Africa; Novartis Biosciences, Peru; Novartis Europharm, Greece; Novartis Healthcare, Philippines; Novartis Pharma, Switzerland; Novartis Pharmaceuticals, Canada; Novartis Pharmaceuticals UK, United Kingdom

STARLIX Novartis Pharma, Germany

Starlix Combi (Nateglinide and Metformin) Novartis, Egypt

Starlix mite Novartis Pharma, Switzerland

Starnet Genovate, Taiwan

Starsis Astellas, Japan

Tang Ling Zhijun, China

Tang Na Zhongyi Pharmaceutical, China

Tang Rui Deyuan Pharmaceutical, China

Tang Yi Global Pharmaceutical, China

Teglix Biofarma, Turkey

Trazec Novartis, Portugal

Wan Su Xin Wanbang Biochemical Pharmaceutical Company, China

Xi Rui Ruinian Qianjin Pharmaceutical, China

Ya Li Ding Yabang Pharmaceutical, China

Yi Ke Xian Shihuida Group, China

Yi Ke Ya Xin Chongqing Kang er Wei Pharmaceutical Co. Ltd, China

Yi You Li An Beijing DongFang XieHe Medical Biotechnology Co. Ltd, China

Glossary

Click for further information on drug naming conventions and International Nonproprietary Names .

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Was this page helpful?

Drugs. com Mobile Apps

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

Skyrim Kinect Commands, Kenicet

Skyrim:Kinect Commands

See Dragon Shouts for a list of both English and Dragon Language commands .

In order to activate the shouts, they must be unlocked at the level you are trying to use.

Shouts can be said in English or Dragon Language.

English shouts can be used without holding . while Dragon Language shouts require that be held (If you're having trouble casting the shouts, try to say them in a fluent pace at a fast speed).

Favorites Menu and Hotkeying Equipment

Only usable in the Favorites menu.

ASSIGN <hotkey command> sets the selected item to the spoken hotkey. <hotkey command> can be any of the following:

The following are only usable during main gameplay.

EQUIP <hotkey command>

Equips item in the default hand

EQUIP LEFT <hotkey command>

Equips item in the Left hand, if possible.

Equips item in the Right hand, if possible.

EQUIP DUAL <hotkey command>

Equips item in both hands, if possible.

EQUIP SWORD AND SHIELD EQUIP MACE AND SHIELD EQUIP AXE AND SHIELD EQUIP DAGGER AND SHIELD

Equips the item assigned to the Sword / Mace / Axe / Dagger hotkey in the right hand, and the item assigned to the Shield hotkey in the left hand.

EQUIP DUAL WEAPONS

Equips the item assigned to the DualWieldLeft hotkey in the left hand, and the item assigned to the DualWieldRight hotkey in the right hand.

Piroxicam Medlineplus Drug Information, Exipan

Piroxicam

People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as piroxicam may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time. Do not take an NSAID such as piroxicam if you have recently had a heart attack, unless directed to do so by your doctor. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech.

If you will be undergoing a coronary artery bypass graft (CABG; a type of heart surgery), you should not take piroxicam right before or right after the surgery.

NSAIDs such as piroxicam may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, or drink large amounts of alcohol while you are taking piroxicam. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). Also tell your doctor if you have or have ever had ulcers or bleeding in your stomach or intestines or other bleeding disorders. If you experience any of the following symptoms, stop taking piroxicam and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools.

Keep all appointments with your doctor and the laboratory. Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to piroxicam. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with piroxicam and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www. fda. gov/Drugs/DrugSafety/ucm085729.htm ) or the manufacturer's website to obtain the Medication Guide.

Why is this medication prescribed?

Piroxicam is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Piroxicam is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

How should this medicine be used?

Piroxicam comes as a capsule to take by mouth. It is usually taken once or twice a day. Take piroxicam at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take piroxicam exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Piroxicam will help control your symptoms but will not cure your condition. It may take 8 to 12 weeks or longer before you feel the full benefit of piroxicam.

Other uses for this medicine

Piroxicam is also sometimes used to treat gouty arthritis (attacks of severe joint pain and swelling caused by a build-up of certain substances in the joints) and ankylosing spondylitis (arthritis that mainly affects the spine). It is also sometimes used to relieve muscle pain and swelling, menstrual pain, and pain after surgery or childbirth. Talk to your doctor about the risks of using this medication for your condition.

What special precautions should I follow?

Before taking piroxicam,

tell your doctor and pharmacist if you are allergic to piroxicam, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients in piroxicam capsules. Ask your pharmacist for a list of the inactive ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARBs) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, in Azor, in Benicar HCT, in Tribenzor), telmisartan (Micardis, in Micardis HCT, in Twynsta), and valsartan (in Exforge HCT); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal, Innopran); diuretics ('water pills'); lithium (Lithobid); medications for diabetes; methotrexate (Otrexup, Rasuvo, Trexall); and phenytoin (Dilantin, Phenytek). Your doctor may need to change the doses of your medication or monitor you more carefully for side effects.

tell your doctor if you have or have ever had asthma, especially if you also have frequent stuffy or runny nose or nasal polyps (swelling of the lining of the nose); heart failure; swelling of the hands, feet, ankles, or lower legs ; or liver, or kidney disease.

tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breastfeeding. If you become pregnant while taking piroxicam, call your doctor.

talk to your doctor about the risks and benefits of taking piroxicam if you are 65 years of age or older. Older adults should usually take lower doses of piroxicam for short periods of time because higher doses taken regularly may not be more effective and are more likely to cause serious side effects.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking piroxicam.

What special dietary instructions should I follow?

Piroxicam may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more piroxicam until you speak to your doctor.

vision problems

unexplained weight gain

shortness of breath or difficulty breathing

swelling in the abdomen, ankles, feet, or legs

fever

blisters

joint pain

rash

itching

hives

swelling of the eyes, face, lips, tongue, throat, arms, or hands

difficulty breathing or swallowing

hoarseness

pale skin

fast heartbeat

excessive tiredness

unusual bleeding or bruising

lack of energy

upset stomach

loss of appetite

pain in the upper right part of the stomach

flu-like symptoms

yellowing of the skin or eyes

cloudy, discolored, or bloody urine

back pain

difficult or painful urination

Piroxicam may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo. gl/c4Rm4p ) for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the following:

lack of energy

drowsiness

upset stomach

vomiting

stomach pain

bloody, black, or tarry stools

vomiting a substance that is bloody or looks like coffee grounds

difficulty breathing

coma (loss of consciousness for a period of time)

What other information should I know?

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

Ethambutol - American Chemical Society, Servambutol

Molecule of the Week

Ethambutol is a drug used, alone or in combination with other drugs, to treat tuberculosis and other infections. It is sold under the trade names Myambutol (X-GEN Pharmaceuticals) and Servambutol (Sandoz). Although it is effective, it has several adverse side effects, such as vision, liver, and allergy problems.

L. L. Kiessling (University of Wisconsin–Madison), in her Fred Kavli Innovations in Chemistry Lecture at the spring 2015 ACS National Meeting in Denver, described ethambutol as “a not great drug”. She advocated targeting microbial cell-surface carbohydrates to combat mycobacterial diseases. In particular, she suggested galactofuranoses as particularly attractive targets for protein antibiotics.

More about this molecule from CAS, the most authoritative and comprehensive source for chemical information.

Molecule of the Week —Menu

Share this page:

Copyright © 2016 American Chemical Society

1155 Sixteenth Street, NW, Washington, DC 20036, USA, service@acs. org. 1-800-333-9511 (US and Canada), 614-447-3776 (outside North America)

Still there, or gone to get coffee.

For your security, this online session is about to end due to inactivity.

If you do not respond, everything you entered on this page will be lost and you will have to login again.

Time remaining: 00:00

Hydrochlorothiazide - Blood Pressure, Fempress Plus

Blood Pressure - Fempress plus (Brand name: hydrochlorothiazide)

Hydrochlorothiazide is used for treating high blood pressure. It is also used to treat fluid buildup in the body caused by certain conditions (e. g. heart failure, liver cirrhosis, kidney problems) or medicines (e. g. corticosteroids, estrogen). It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Use Hydrochlorothiazide as directed by your doctor.

Take Hydrochlorothiazide by mouth with or without food. Hydrochlorothiazide may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. Ask your health care provider any questions you may have about how to use Hydrochlorothiazide. Drug Class and Mechanism

Hydrochlorothiazide is a thiazide diuretic. It helps the kidneys to remove fluid from the body.

If you miss a dose of Hydrochlorothiazide and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Store Hydrochlorothiazide between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hydrochlorothiazide out of the reach of children and away from pets.

Do not use Hydrochlorothiazide if:

you are allergic to any ingredient in Hydrochlorothiazide; you are unable to urinate; you are taking dofetilide or ketanserin. Contact your doctor or health care provider right away if any of these apply to you.

Important : Hydrochlorothiazide may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Hydrochlorothiazide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Hydrochlorothiazide may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Your doctor may also prescribe a potassium supplement for you. If so, take the potassium supplement exactly as prescribed. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor. Tell your doctor or dentist that you take Hydrochlorothiazide before you receive any medical or dental care, emergency care, or surgery. Tell your doctor if you will be exposed to high temperatures. The risk of certain side effects (eg, low blood sodium levels) may be increased in hot weather. Hydrochlorothiazide may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Hydrochlorothiazide. Use a sunscreen or wear protective clothing if you must be outside for more than a short time. Hydrochlorothiazide may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away. Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. Lab tests, including kidney function, blood pressure, and electrolyte levels, may be performed while you use Hydrochlorothiazide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Pregnancy and breast-feeding: Hydrochlorothiazide may cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hydrochlorothiazide while you are pregnant. Hydrochlorothiazide is found in breast milk. If you are or will be breast-feeding while you use Hydrochlorothiazide, check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; dizziness; lightheadedness (especially when sitting up or standing); loss of appetite; nausea; temporary blurred vision. Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; dark urine; decreased urination; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; increased thirst; joint pain, swelling, warmth, or redness (especially of the big toe joint); mental or mood changes; muscle pain or cramps; numbness or tingling; red, swollen, blistered, or peeling skin; seizures; severe or persistent dizziness; severe or persistent nausea or stomach pain; shortness of breath; unusual bruising or bleeding; unusual drowsiness, restlessness, tiredness, or weakness; unusually dry mouth; vomiting; yellowing of the eyes or skin.

If you have any questions about Hydrochlorothiazide, please talk with your doctor, pharmacist, or other health care provider. Hydrochlorothiazide is to be used only by the patient for whom it is prescribed. Do not share it with other people.

Odizol, Odizol

Omeprazole

Click for further information on drug naming conventions and International Nonproprietary Names .

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Was this page helpful?

Glukozamin, Glukozamin

Glucosamine / Chondroitin Supplements | Glucosamine / Chondroitin Products | at Puritan's Pride glucosamine, glucosamine supplements, glucosamine vitamins, chondroitin, chondroitin supplements, chondroitin vitamins, glucosamine chondroitin, glucosamine chondroitin supplements, glucosamine chondroitin vitamins, glucosamine chondroitin msm joint soother, joint soother, glucosamine chondroitin complex, glucosamine msm complex, glucosamine sulfate, glucosamine complex with chondroitin, joint soother liquid Glucosamine and Chondroitin promote joint comfort, flexibility and mobility when taken together. Help lubricate joints and revitalize cartilage. Promote and support comfortable movement. http://www. puritan. com/glucosamine-chondroitin-045

Glucosamine / Chondroitin Supplements

Glucosamine and Chondroitin support joint comfort. mobility and flexibility.** Glucosamine and Chondroitin work together to support joint health.**

Glucosamine and Chrondroitin help lubricate joints and promote healthy cartilage.**

Glucosamine and Chondroitin promote and support comfortable movement.**

Above Statements not applicable to all products below

When you think about it, the joints in our bodies are pretty complicated things. We demand a lot from them, too. We expect them to make repetitive movements day after day, month after month, year after year. They must fight off gravity, repair themselves after overuse, and absorb the pounding we regularly give them while running or playing sports.

It's no surprise that cartilage health is a concern all over the world. As people age, decreased joint function is relatively common. In fact, a majority of Americans will have joint concerns by the time they reach 65.

Joints like the shoulder, knee and hip are surrounded by a tough, fibrous material which is lined by a thin membrane. That membrane produces a lubricating liquid called synovial fluid . As joints age, they lose cartilage partly because aging changes the consistency of the synovial fluid and interferes with its ability to lubricate and nourish the joint.

Normal cartilage is composed of water, collagen and molecules called proteoglycans which are basically complex combinations of protein and sugar. Two important proteoglycans are keratin and chondroitin sulfate and glucosamine and other related compounds are the basic components of each.

There are several different forms of glucosamine glucosamine sulfate . glucosamine hydrochloride (HCI) . and N-acetyl-glucosamine . Most supplements contain the sulfate or HCI form. Glucosamine occurs naturally in the fluid surrounding the joints, and the sulfate form is also found in the shells of shellfish. It can also be produced in a laboratory.

Glucosamine and chondroitin are especially good for anyone seeking joint and connective tissue support.

Glucosamine and chondroitin help support the joints.

Glucosamine and chondroitin are top joint ingredients. They promote joint comfort, flexibility, and mobility when taken in combination.

Glucosamine and chondroitin are key components in cartilage.

Glucosamine provides cartilage support while chondroitin helps to maintain joint cartilage.

Glucosamine and chondroitin act as lubricating factors.

Glucosamine and chondroitin promote range of motion.

Glucosamine (or glucosamine sulfate) has multiple functions in the body, but its value is mostly related to its benefits for cartilage. Here are its most important points:

Glucosamine sulfate is an amino sugar used to create the cushioning fluids and tissues around joints.

Glucosamine is commonly used to support joint comfort and function. Glucosamine also can support cartilage maintenance by supplying the raw materials needed for cartilage health.

Glucosamine stimulates the process by which sulfur is incorporated into cartilage. That's important because sulfur is essential to cartilage maintenance.

Glucosamine can be important for athletes who put a lot of strain on their joints.

There are no major food sources of glucosamine; it can be obtained only through supplements.

The structure function claims made on this website have not been evaluated by the Food and Drug Administration. These dietary supplement products are not intended to diagnose, treat, cure, or prevent any disease.

¦ Puritan's Pride provides these articles for information only. They are not approved or recommended by us, do not provide medical advice, diagnosis, or treatment, and are not meant to replace professional medical advice or apply to any products.

** These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition. The information on this website is not intended to diagnose, treat, cure or prevent any disease. Never disregard medical advice or delay in seeking it because of something you have read on the Puritan's Pride site. Product sold on this site are for personal use and not for resale. All orders placed through this website are subject to Puritan's Pride acceptance, in its sole discretion. This means that Puritan's Pride may refuse to accept, or may cancel, any order, whether or not it has been confirmed, without liability to you or any third party. Puritan's Pride reserves the right to discontinue any program or offer.

If you would like to unsubscribe from future Puritan's Pride emails, please click here to unsubscribe.

^ Same item, same size Puritan's Pride® brand products, discount already reflected in the applicable product price. Certain products, including clearance section items, may be excluded. All products subject to availability. To expedite orders, we may substitute bottles if ordered product or quantity is out of stock. Terms and conditions subject to change. Free Shipping applies to orders shipping within the contiguous 48 U. S. states; valid on orders of $49.95 or more and will automatically apply to your cart at checkout; not valid on orders greater than $1,000.00 USD or on prior purchases. A flat rate shipping fee of $3.95 will apply to orders under $49.95. Sale prices and/or discounts are not valid on orders greater than $1000.00 USD or on prior purchases.

Puritan's Pride, 1233 Montauk Highway, PO Box 9001, Oakdale, NY 11769-9001

Apofarm Group Unia Hurtowni Aptekarskich Sp?Ka Z O, Apofarm

Financial reports of Polish companies on an e-mail

APOFARM GROUP UNIA HURTOWNI APTEKARSKICH Sp?ka z o. o.

Zam?w skany sprawozda? finansowych z Monitora Polskiego B:

A typical financial report includes:

Balance sheet,

Income statement,

Cash-flow,

Changes specification in one's own capital (fund)

Controller's opinion,

Introduction to the financial report.

Description

Photo formats of the financial report,

PDF format, printable version in A4 format,

The resolution 200 dpi - High quality of the printout guaranteed,

In order to open the files PDF - Acrobat Reader browser is required.

Sending

Immediately after the payment accounting,

At e-mail.

Possible means of payment

Credit Card prepayment,

Transfer prepayment.

In order to order

Add to the basket chosen financial reports,

Place an order

Pay for the order.

The financial reports of polish companies in PDF on your e-mail.

Cetril, Cetril

Os proprietarios pioneiros de boa fe, apos honrarem pecuniariamente os seus compromissos com a parceladora do sitio Estrela, edificadas as casas, perceberam que o beneficio da rede eletrica divulgada pelos corretores e prometida pelos parceladores estava praticamente impossivel de se alcancar, devido a clandestinidade daqueles quatro projetos que era desconhecida de todos.

Os mais abastados foram se resolvendo com a compra de moto-gerador que possibilitava iluminar suas residencias e manter ao menos uma televisao ligada. Geladeira, chuveiro eletrico, torneiras eletricas, nem pensar. Alem disto, estes mais afortunados prestavam favores para alguns caseiros carregando baterias veiculares para alimentar aquelas TVs de 5" que suportavam uma semana de carga.

Roberto Pasquale, " in-memoriam ", entao proprietario da fracao ideal 16-I, na epoca (1990) tomou a frente desse problema e iniciou contatos com as concessionarias e permissionarias da regiao para tentar viabilizar a entrada da rede primaria para dentro do loteamento Floresta IV quando entao constatou-se que sem a regularizacao do empreendimento junto aos cartorios de registro de imoveis, essa benfeitoria nao seria possivel.

Reunioes foram realizadas com a parceladora Makopil. Esta por sua vez garantia de que a rede eletrica seria conseguida junto a Eletropaulo dada a influencia politica de um de seus diretores no municipio de Sao Paulo, que teria livre transito com o Governador do Estado da epoca. No entanto, nada foi exequivel. Por um lado a Eletropaulo afirmava nao poder cruzar linhas de transmissao com a Cetril. A Cetril por sua vez declinava de adentrar com a sua rede, ao loteamento, em face a clandestinidade do empreendimento, podendo, se o fizesse, sofrer com consequencias judiciais indesejaveis. Por outro lado, a regularizacao do Floresta IV implicava na compra de mais de 110.000 m? de terras para atender uma area de reserva institucional, correspondente a 35% da area total parcelada. Esta area teria que ser suportada pecuniariamente por todos aqueles proprietarios. Para se defender alegava a parceladora Makopil que o metro quadrado vendido foi muito barato, esquecendo - se de que o preco pago foi por todos os compradores fora o preco ofertado por ela.

A obtencao da rede eletrica via Eletropaulo estava descartada. A Cetril, acenava em uma direcao a de constituir uma Associacao com personalidade juridica regular, que legalmente representasse os interessados, atraves da qual, levaria a rede primaria para o empreendimento. Tentou-se a sua constituicao de uma primeira Associacao, para os quatro projetos, Floresta I, II, III e IV, a APROF. O baixo interesse de uma parcela consideravel de proprietarios nao nos permitia conseguir um " quorum " para aprovacao com 50% mais 1 o que sempre inviabilizava a sua constituicao. Nove anos se passaram e geradores eram roubados, a Iluminacao retroagia atraves dos candieiros, banhos frios constantes, a conservacao de alimentos se dava atraves de caixas termicas com pedras de gelo, enfim, muita dificuldade e pouco conforto.

Diante desse quadro, resolveu-se abandonar a ideia de uma Associacao que congregasse os interesses dos quatro projetos passando-se a dedicarem-se apenas aos interesses do Floresta IV, onde um grupo de proprietarios era mais unido e decidido. Tres estatutos foram elaborados, mas nenhum levado a cabo. A ultima tentativa sucumbiu pelo simples fato das assinaturas nas atas de constituicao nao terem sido colhidas por aqueles que se propuseram fazer. Mais uma vez a constituicao ficou a beira do caminho. Em um dado momento, uma parte desse grupo de proprietarios, de posse de uma planta baixa, apocrifa, desprovida de ART / memorial descritivo resolveu reconhecer a firma do Engenheiro Abrao, cujo carimbo estava aplicado no centro do documento e juntamente com uma propensa candidata a vereadora para a Camara Municipal de Ibiuna, resolveram tomar a frente dessa questao. Estes agendaram reuniao com o gerente administrativo da Cetril da epoca, na pessoa do Sr. Altair, para tentarem fechar a questao quanto a contratacao da rede eletrica achando que desta forma tudo seria possivel. O atual presidente, que sempre esteve a frente disto, que presidiu a comissao provisoria que passou a tratar diretamente e a defender os interesses de todos os proprietarios, tanto na regularizacao do loteamento quanto na obtencao da rede eletrica com a Makopil de nada sabia e, atraves de um telefonema de um desses proprietarios foi informado sobre essa reuniao e que a sua presenca la era desejavel uma vez conhecer profundamente todos os detalhes sobre essa questao. Nao foi muito receptiva a presenca do atual presidente naquela reuniao.

Iniciadas as conversacoes. o Sr. Altair tomando a palavra quis saber de pronto sobre o estatuto e CNPJ da Associacao. Como isto nao havia sido providenciado por aqueles senhores que protagonizaram aquela reuniao, esta praticamente se encerrou naquele momento. Ficou acertado que o projeto de eletrificacao so seria examinado e viabilizado quando de posse desses documentos e mais: em quanto tempo o atual presidente constituiria a Associacao e disponibilizaria esses documentos sem os quais nada seria possivel. Andamos em circulo eis que todas as acoes recairam na mesma pessoa que sempre esteve a frente disto. Assim. a ASF IV f oi constituida e as renegociacoes com a Cetril, retomadas e concluidas.

Projetos de viabilidade tecnica e topografia foram desenvolvidos pela Cetril, permissoes de passagens por dentro de propriedades foram providenciadas pelos administradores da ASF IV para manter os requisitos minimos de altitude do embarrigamento da linha em relacao ao solo e ao linhao Embu-Guacu/Bauru existente no local, orcamentos apresentados que orbitaram em torno de R$70.000,00 na epoca condicoes de pagamento, contrato celebrado com a responsabilidade civil do atual presidente e do vice-presidente Dorivaldo Antonio Colla " in-memoriam " servicos de posteamentos e instalacao da rede que contratualmente fora prometida a sua entrega dentro de 60 dias da assinatura do contrato fora disponibilizada aos proprietarios num prazo maximo de 30 dias. Este investimento fora suportado na epoca por apenas 28 (*) proprietarios de um grupo de 56 (*) . Por se tratar de uma Cooperativa, a rede eletrica por forca de contrato, foi doada a propria Cetril e o valor investido transformado em quotas de participacao da ASF IV na Cooperativa.

(*) Estes sao numeros aproximados da epoca.

Buy Cetafloxo - Ciprofloxacin - Online Without Prescriptions, Cetafloxo

Ciplox (Cetafloxo)

Ciplox is used to treat different types of bacterial infections. It may also be used to prevent or slow anthrax after exposure.

Take Cipro exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take Cipro with a full glass of water (8 ounces). Drink several extra glasses of fluid each day while you are taking this medicine. Cipro may be taken with or without food, but take it at the same time each day. Shake the oral suspension (liquid) for at least 15 seconds just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

When taking the Cipro oral liquid, swallow it without chewing the medicine beads you may notice in the liquid.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Do not take Cipro with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products as part of a regular meal, but do not use them alone when taking Cipro. They could make the medication less effective.

Take Cipro for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Cipro will not treat a viral infection such as the common cold or flu.

Store Cipro at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Take exactly as prescribed by your Health Provider.

Store this medicine at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

You should not use Ciplox if you are taking tizanidine (Zanaflex), if you have a history of myasthenia gravis, or if you are allergic to ciprofloxacin or similar antibiotics such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and others.

Before taking Ciplox, tell your doctor if you have a heart rhythm disorder, kidney or liver disease, joint problems, diabetes, muscle weakness or trouble breathing, a condition called pseudotumor cerebri, a history of seizures, a history of head injury or brain tumor, low levels of potassium in your blood, a personal or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

Do not take Ciplox with dairy products such as milk or yogurt, or with calcium-fortified juice. Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 6 hours before or 2 hours after you take Ciplox. Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

You should NOT take Ciplox if:

you are also taking tizanidine (Zanaflex);

you have a history of myasthenia gravis; or

you are allergic to ciprofloxacin or similar medications such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

To make sure you can safely take Ciplox, tell your doctor if you have any of these other conditions:

heart rhythm disorder, especially if you take quinidine (Quin-G), disopyramide (Norpace), bretylium (Bretylol), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), or sotalol (Betapace);

a history of head injury or brain tumor;

a condition called pseudotumor cerebri (high pressure inside the skull that may cause headaches, vision loss, or other symptoms);

a history of allergic reaction to an antibiotic;

joint problems;

kidney or liver disease;

epilepsy or seizures;

diabetes;

muscle weakness or trouble breathing;

low levels of potassium in your blood (hypokalemia); or

a personal or family history of Long QT syndrome.

FDA pregnancy category C. It is not known whether Ciplox will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using it. Ciprofloxacin passes into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Ciplox may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions. Do not share Ciplox with another person (especially a child), even if they have the same symptoms you have.

Get emergency medical help if you have any of these signs of an allergic reaction to Ciplox: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Ciplox and call your doctor at once if you have a serious side effect such as:

severe dizziness, fainting, fast or pounding heartbeats;

sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;

diarrhea that is watery or bloody;

confusion, hallucinations, depression, unusual thoughts or behavior;

seizure (convulsions);

severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

pale or yellowed skin, dark colored urine, fever, weakness;

urinating less than usual or not at all;

easy bruising or bleeding;

numbness, tingling, or unusual pain anywhere in your body;

the first sign of any skin rash, no matter how mild; or

severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects:

nausea, vomiting;

dizziness or drowsiness;

blurred vision;

feeling nervous, anxious, or agitated; or

sleep problems (insomnia or nightmares).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Customers who bought this product also bought

Buy Generic For Pramin 10mg And Save $, Pramin

Danielle Jolla, United States says, "I love your online pharmacy Because of your quick shipping and reasonable prices."

Jill Barrella, United States says, "Seemed easy to purchase, reasonable prices. Good customer service when I used it."

Brian Pavey, United States says, "I am very satisfied with IDM and plan on making more purchases in the future. IDMs prices are low which makes it very compelling to use over conventional pharmacies with high copays and more restrictions continually implemented."

Eric Gonzales, United States says, "The website is very user friendly, there is a lot of variety and checking out was easy."

Albert Martinez, United States says, "Very organized and efficient concerning delivery and products are great. Very satisfied, impressed with delivery and product."

Natalie Wallace, United States says, "I absolutely love getting my medications at a great price and I always get that here. And I recommend this site to my family and friends."

Just look at what our Tens of Thousands of Satisfied Customers say about us

Graphical representation showing How to order at International Drug Mart

Generic Name: Metoclopramide

Generic for Pramin* (Metoclopramide) is used to treat the symptoms of diabetic gastroparesis such as nausea, vomiting, heartburn, indigestion, persistent fullness after meals, and loss of appetite. It is also used in the short-term treatment of heartburn in people with gastroesophageal reflux disorder (GERD). By increasing the muscle contractions in the upper digestive tract, Generic for Pramin* aids the passage of food. This medicine may also be used to treat other conditions as determined by your doctor. Read More>>

We sell only Metoclopramide . the generic version of Pramin *. Buy Now and Save with Generics.

*We do not sell Pramin brand.

Facts about Generic Drugs

Generic drugs are chemically identical to brand-name drugs in terms of active ingredient(s), intended use, quality, dosage, safety, bioavailability and effectiveness.

Generic drugs are cheaper than brand-name drugs.

What is Generic for Pramin* used for?

Generic for Pramin* (Metoclopramide) is used to treat the symptoms of diabetic gastroparesis such as nausea, vomiting, heartburn, indigestion, persistent fullness after meals, and loss of appetite. It is also used in the short-term treatment of heartburn in people with gastroesophageal reflux disorder (GERD). By increasing the muscle contractions in the upper digestive tract, Generic for Pramin* aids the passage of food. This medicine may also be used to treat other conditions as determined by your doctor.

What is the recommended dosage of Generic for Pramin*?

The dosage of Generic for Pramin* prescribed to each patient will vary. Always follow your physician's instructions and/or the directions on the prescription drug label.

Take Generic for Pramin* on an empty stomach, at least 30 minutes before a meal.

What if you miss a dose of Generic for Pramin*?

If your physician has instructed or directed you to take Generic for Pramin* medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

What if you overdose on Generic for Pramin*?

Any medication taken in excess can have serious consequences. If you suspect an overdose of Generic for Pramin*, seek medical attention immediately.

What other drugs could interact with Generic for Pramin*?

It may be noted that drugs other than those listed above may also interact with Generic for Pramin*

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Generic for Pramin*, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

Generic for Pramin* can interact with irritable bowel medications, bronchodilators, and urinary medications.

Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

What are the side effects of Generic for Pramin*?

Like other medicines, Generic for Pramin* can cause some side effects. If they do occur, the side effects of Generic for Pramin* are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

It is pertinent to note that side effects of Generic for Pramin* cannot be anticipated. If any side effects of Generic for Pramin* develop or change in intensity, the doctor should be informed as soon as possible.

Generic for Pramin* can cause side effects such as sleeplessness, dizziness, nausea, diarrhea, headache, and dry mouth. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Generic for Pramin*

What are the questions to ask your doctor before taking Generic for Pramin*?

Is it possible for me to take Generic for Pramin* with other drugs? Should certain beverages, foods and other products be avoided when I take Generic for Pramin*? What are the possible drug interactions of Generic for Pramin*? How will Generic for Pramin* work in my body? How should Generic for Pramin* be taken? How to reduce the risk of Generic for Pramin* drug interactions and side effects?

Note

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Generic for Pramin* is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Bloxham School, Bloxan

Welcome to Bloxham

Bloxham School is an independent, co-educational boarding and day school for students aged 11 to 18. Situated in north Oxfordshire, Bloxham offers a rural setting whilst being easily accessible from London and the Home Counties.

Admissions

Choosing the best secondary school to suit your child’s needs can be a daunting process. Our Admissions Department are happy to advise and discuss any questions you may have regarding life and learning at Bloxham School.

Parents' Information

Bloxham School Parents' Information gives information that is useful for both current and prospective parents of the school, including minibus routes, uniform lists and the school calendar

Our Five Hallmarks #01

A Passion for Learning

Fostering creativity and the capacity for dynamic, independent and critical thought.

Our Five Hallmarks #02

A balanced curriculum

A challenging academic programme, complemented by a broader curriculum which inspires curiosity, rigour and ambition.

Our Five Hallmarks #03

A gold standard of care

Nurturing the well-being of all within the setting of a boarding community.

Our Five Hallmarks #04

The Development of Character

Through promotion of responsibility, generosity, resilience and imagination.

Our Five Hallmarks #05

Christian Values

Nurturing a compassionate spirit so that our students become a force for good in an ever-changing world.

Sixth Form Seminar Series - Mastering the Art of Giving an Outstanding Presentation

Taucaron, Taucaron

Taucaron

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Was this page helpful?

Vasomil - 40 Tablets; Vasomil - 80 Tablets; Vasomil - 120 Tablets, Vasomil

PROPRIETARY NAME (and dosage form):

VASOMIL - 40 TABLETS VASOMIL - 80 TABLETS VASOMIL - 120 TABLETS

COMPOSITION: Each tablet contains: Vasomil - 40 Verapamil hydrochloride 40 mg Vasomil - 80 Verapamil hydrochloride 80 mg Vasomil - 120 Verapamil hydrochloride 120 mg

PHARMACOLOGICAL CLASSIFICATION: A 7.1.4 - Vasodilators - Coronary and other medicines used in angina pectoris

PHARMACOLOGICAL ACTION: Verapamil hydrochloride is a calcium channel blocker that reduces myocardial oxygen consumption in vitro directly by intervening in the energy consuming metabolic processes of the myocardial cell, and indirectly by diminishing the peripheral resistance (afterload). It prolongs impulse conduction in the A. V. node.

INDICATIONS: Angina pectoris, supraventricular tachydysrythmia.

CONTRA-INDICATIONS: Hypersensitivity to verapamil. Safety in pregnancy and lactation has not been established. Verapamil is contra-indicated in hypotension, cardiogenic shock, marked bradycardia, second and third-degree atrioventricular block and uncompensated heart failure. Verapamil is also contra-indicated in the sick-sinus syndrome unless a pacemaker is fitted.

DOSAGE AND DIRECTIONS FOR USE:

1 to 2 tablets three times daily.

1 to 2 tablets three times daily.

1 tablet three times daily.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS: Adverse effects connected with verapamil’s pharmacological effects on cardiac conduction can arise and may be particularly severe in patients with hypertrophic cardiomyopathies. Adverse effects on the heart include bradycardia, atrioventricular block, worsening heart failure and transient asystole. The most troublesome non-cardiac adverse effect is constipation. Nausea may occur but is less frequently reported. Other adverse effects include hypotension, dizziness, flushing and headaches. There have been reports of skin reactions. Some cases of abnormal liver function and hepatotoxicity have been reported. Gingival hyperplasia has occurred. Gynaecomastia has been reported less frequently. In patients with atrial flutter or fibrillation and an accessory pathway with antero-grade conduction, e. g. Wolff-Parkinsons White syndrome, verapamil may induce severe ventricular tachycardia. Doses of verapamil should be reduced m patients with impaired liver function. Sudden withdrawal of verapamil might be associated with an exacerbation of angina.

Interactions: During the simultaneous administration of Vasomil and medication with cardio-depressive effect and/or inhibiting effect on atrioventricular conduction (e. g. beta-adrenergic blockers), the patient should be observed for additive effects. Rises in digoxin plasma levels under concomitant administration of Vasomil have been reported. Doctors should be alert for symptoms of possible digitalis intoxication.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT: In overdosage there may be severe cardiotoxicity and profound hypotension. In overdosage with verapamil by mouth the stomach should be emptied by lavage; activated charcoal may be administered. Treatment of cardiovascular effects is supportive and symptomatic.

IDENTIFICATION: Vasomil - 40 A yellow, film-coated biconvex tablet. Vasomil - 80 A yellow, film-coated biconvex tablet, bisected on one side Vasomil - 120 A yellow, film-coated biconvex tablet, bisected on one side.

Blister packs with 100 tablets Securitainers with 500 tablets

Blister packs with 100 tablets Securitainers with 250 tablets

Blister packs with 100 tablets Securitainers with 250 tablets

STORAGE INSTRUCTIONS: Store below 25°C, in airtight containers and protect from light. KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBERS: Vasomil - 40 H/7.1.4/237 Vasomil - 80 M/7.1.4/179 Vasomil - 120 Y/7.1.4/328

NAME AND BUSINESS ADDRESS OF THE APPLICANT: Pharmacare Limited 7 Fairclough Road Korsten PORT ELIZABETH 6001

DATE OF PUBLICATION OF THIS PACKAGE INSERT: 19/06/1991

D202 A & S PRINTERS .

Updated on this site: May 2000 Current: July 2003 Source: Community Pharmacy SAEPI HOME PAGE TRADE NAME INDEX GENERIC NAME INDEX FEEDBACK Information presented by Malahyde Information Systems © Copyright 1996-2003

Dramamine (Dimenhydrinate) Report For Patients Like You, Vertirosan

Dramamine treatment report

See 0 evaluations from 0 patients with major perceived effectiveness

See 1 evaluation from 1 patient with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

This item is relevant to you: Dizziness

See 1 evaluation from 1 patient with major perceived effectiveness

See 1 evaluation from 1 patient with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

This item is relevant to you: Insomnia

See 1 evaluation from 1 patient with major perceived effectiveness

See 0 evaluations from 0 patients with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

This item is relevant to you: Lightheadedness

See 0 evaluations from 0 patients with major perceived effectiveness

See 0 evaluations from 0 patients with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

See 0 evaluations from 0 patients with major perceived effectiveness

See 0 evaluations from 0 patients with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

This item is relevant to you: Motion sickness

See 1 evaluation from 1 patient with major perceived effectiveness

See 0 evaluations from 0 patients with moderate perceived effectiveness

See 0 evaluations from 0 patients with slight perceived effectiveness

See 0 evaluations from 0 patients with none perceived effectiveness

See 0 evaluations from 0 patients with unknown perceived effectiveness

Dimenhydrinate is used to prevent and treat nausea, vomiting, dizziness, and vertigo associated with motion sickness.

Dimenhydrinate may also be used for purposes other than those listed in this medication guide.

Precautions

Before taking this medication, tell your doctor if you have

kidney or liver disease,

an enlarged prostate,

difficulty urinating,

bladder problems,

glaucoma,

asthma, or

an irregular heartbeat or any other type of heart disease.

You may not be able to take dimenhydrinate, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Dimenhydrinate is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take dimenhydrinate without first talking to your doctor if you are pregnant.

Dimenhydrinate passes into breast milk and may harm a nursing baby. Do not take dimenhydrinate without first talking to your doctor if you are breast-feeding a baby.

Dimenhydrinate is not recommended for use by children younger than 2 years of age, except under the direction of a doctor.

Use caution when driving, operating machinery, or performing other hazardous activities. Dimenhydrinate may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking dimenhydrinate.

Instructions

Seek emergency medical attention.

Symptoms of a dimenhydrinate overdose include drowsiness, seizures or convulsions, difficulty breathing, and death.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Side effects

Stop taking dimenhydrinate and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take dimenhydrinate and talk to your doctor if you experience

drowsiness or dizziness;

restlessness, excitation, nervousness, or insomnia;

blurred or double vision;

dry mouth, nose, or throat;

decreased appetite, nausea, vomiting, or diarrhea;

difficulty urinating; or

an irregular or fast heartbeat.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Interactions

Dimenhydrinate may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Drugs other than those listed here may also interact with dimenhydrinate. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Other Names

Dramamine, Dramoject, Driminate, Dymenate, Hydrate, Triptone, dimenhyDRINATE, and DMH

Available Strengths & Dosages

Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

Last updated: September 21, 2016

What is the most important information I should know about dimenhyDRINATE?

Use caution when driving, operating machinery, or performing other hazardous activities. Dimenhydrinate may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking dimenhydrinate.

Warning

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Doxylin (Doxycycline) Drug, Doxylin

Doxylin

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. This page contains answers to some common questions about Doxylin. It does not contain all the information that is known about Doxylin. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risk of you using this medicine against the benefits he/she expects it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Bookmark or print this page, you may need to read it again.

What Doxylin is used for

Doxylin is an antibiotic used to:

treat certain infections caused by bacteria

prevent certain types of malaria

Doxylin is an antibiotic that belongs to a group of medicines called tetracyclines. It works by killing or stopping the growth of bacteria, which cause infections or make acne worse.

Doxylin also works against parasites that cause malaria. It is sometimes used in combination with other anti-malarial medicines.

Tetracyclines will not work against infections caused by viruses, such as colds or flu.

Ask your doctor if you have any questions about why Doxylin has been prescribed for you.

Your doctor may have prescribed Doxylin for another reason.

This medicine is not addictive.

This medicine is available only with a doctor's prescription.

Before you take Doxylin

When you must not take it

Do not take Doxylin if you are allergic to:

medicines containing doxycycline (e. g. Doryx, Vibramycin)

medicines containing other tetracyclines (e. g. Minomycin, Tetrex)

any of the ingredients listed at the end of this leaflet.

Symptoms of an allergic reaction to a tetracycline antibiotic may include skin rash, itching or hives; swelling of the face, lips, tongue or other parts of the body or other parts of the body; asthma, shortness of breath, wheezing or troubled breathing and fainting.

If you are not sure if you are allergic to any of the above, ask your doctor.

Do not take Doxylin if you are taking preparations containing vitamin A, isotretinoin or etretinate.

Doxylin should not be taken during periods of tooth development (more than 18 weeks into pregnancy or in children 8 years and under).

Doxylin, like other tetracyclines, may cause enamel loss and permanent discolouration (yellow-grey-brown) in developing teeth.

Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or show signs of tampering.

If it has expired or is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take it

Tell your doctor if you have allergies to any other medicines, foods, dyes or preservatives.

Tell your doctor if you have any other health problems.

Tell your doctor if you are pregnant or plan to become pregnant.

Doxylin is not recommended during the last half of pregnancy (see 'When you must not take it' section).

High doses of tetracyclines may also cause liver problems in pregnant women.

Your doctor can discuss with you the risks and benefits of taking Doxylin during pregnancy.

Tell your doctor if you are breastfeeding or plan to breastfeed.

Doxylin passes into breast milk. Your doctor can discuss with you the risks and benefits involved.

Tell your doctor if you are scheduled to have surgery under general anaesthetic.

Tell your doctor if you work outdoors or if you are likely to be exposed to strong sunlight or ultra-violet light (e. g. on a sun bed).

You should avoid exposure to strong sunlight while taking this medicine as your skin may be more sensitive to sunburn than normal.

If you have not told your doctor about any of the above, tell him/her before you start taking Doxylin.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from a pharmacy, supermarket or health food shop.

Some medicines and Doxylin may interfere with each other. These include:

preparations containing vitamin A, including vitamin supplements

preparations containing calcium or iron, including vitamin supplements

antacids, used for indigestion

some medicines used for skin problems such as isotretinoin or etretinate

warfarin, a medicine used to prevent blood clots

another group of antibiotics called penicillins

some anticonvulsant medicines that are used to treat seizures, such as phenytoin or carbamazepine

barbiturates, such as phenobarbitone

methoxyflurane, an anaesthetic

acetazolamide, a medicine used to help the body rid of salt and water

the contraceptive pill (birth control pill).

Doxylin may decrease the effectiveness of some birth control pills.

Your doctor may advise you to use an additional method of contraception while you are taking Doxylin and for 7 days after taking Doxylin.

These medicines may be affected by Doxylin or may affect how well it works. You may need different amounts of your medicine or you may need to take different medicines.

Alcohol may also interfere with the absorption of Doxylin.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Doxylin.

How to take Doxylin

Follow all directions given to you by your doctor or pharmacist carefully.

They may differ from the information contained in this leaflet.

Ask your doctor or pharmacist for help, if you do not understand the instructions on the box.

How much to take

Your doctor will tell you how much you need to take each day and when to take it. This depends on your condition and whether or not you are taking any other medicines.

For treating infections, the usual dose of doxycycline for adults is 200 mg on the first day, followed by 100 mg each day from then on.

For controlling acne, the usual dose for adults is 50 mg a day.

For the prevention of malaria, the usual dose for adults is 100 mg each day, starting two days before entering the malarious area, continuing during the visit, and for four weeks after leaving the area.

Children over 8 years of age may need smaller doses, depending on their weight.

How to take it

Swallow the tablets whole with a full glass of water or milk while sitting or standing upright.

Do not lie down immediately after swallowing Doxylin.

It is important to not lie down for at least half an hour after swallowing your tablet, so that the tablet can move swiftly as possible into the stomach and prevent irritation of the throat or oesophagus (canal taking food from the mouth to the stomach).

When to take it

Take Doxylin during or immediately after a meal, preferably in the morning.

This will reduce the chances of stomach upset.

Take your medicine at about the same time each day.

Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

How long to take it

Keep taking Doxylin for the full time of treatment. Continue taking your medicine even if you begin to feel better after a few days, for as long as the doctor recommends.

If you stop taking your medicine too soon, your infection may not clear completely or your symptoms may return.

For treating infections, Doxylin is usually taken for one to two weeks.

For controlling acne, Doxylin is normally taken over a period of 12 weeks.

For preventing malaria, Doxylin is normally recommended to be taken for up to maximum of 8 weeks. However, your doctor may prescribe Doxylin for longer periods.

If you are not sure how long you should be taking Doxylin, talk to your doctor.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.

Do not take a double dose to make up for the dose you missed.

This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Doxylin. Do this even if there are no signs of discomfort or poisoning.

You may need urgent medical attention. Symptoms of overdose include nausea and vomiting.

While you are taking Doxylin

Things you must do

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Doxylin.

Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.

If you become pregnant while taking this medicine, tell your doctor immediately.

If you are taking Doxylin for an infection and your symptoms do not improve within a few days, or if they become worse, tell your doctor.

If you get severe diarrhoea, tell your doctor or pharmacist immediately. Do this even if it occurs several weeks after you have stopped taking Doxylin.

Diarrhoea may mean that you have a serious condition affecting your bowel. You may need urgent medical care. Do not take any medicines for diarrhoea without checking with your doctor.

If you are taking Doxylin for a long time, visit your doctor regularly so that they can check on your progress.

Your doctor may want you to have some blood tests from time to time. This helps to prevent unwanted side effects.

If you are taking iron or calcium preparations (including vitamin preparations that contain iron or calcium) or antacids, you must take them at least two hours before or two hours after Doxylin to make sure there is no problem with absorption.

If you are about to have any blood tests, tell your doctor that you are taking this medicine.

Doxylin may interfere with the results of some tests.

Things you must not do

Do not take Doxylin to treat any other complaints unless your doctor tells you to.

Do not give your medicine to anyone else, even if they have the same condition as you.

Do not stop taking your medicine or lower the dosage without checking with your doctor.

If you do not complete the full course prescribed by your doctor, all the bacteria causing your infection may not be killed. These bacteria may continue to grow and multiply so that your infection may not clean completely or may return.

Things to be careful of

Protect your skin when you are in the sun, especially between 10am and 3pm. If outdoors, wear protective clothing and use a 30+ sunscreen.

Doxylin may cause your skin to be much more sensitive to sunlight than it is normally. Exposure to sunlight may cause a skin rash, itching, redness, or severe sunburn.

If your skin does appear to be burning, tell your doctor before you take your next dose of Doxylin.

If you get thrush (a fungal infection which can affect the mouth and/or vagina) or any other infection while taking or soon after stopping Doxylin, tell your doctor.

Sometimes use of this medicine allows fungi to grow. These fungi are not killed by Doxylin.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Doxylin.

Like other medicines, Doxylin may have unwanted side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Do not be alarmed by this list of possible side effects.

You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

feeling sick, vomiting, diarrhoea

stomach upset or vomiting

oral thrush (white, furry sore tongue and mouth)

vaginal thrush (sore and itchy vagina, vaginal discharge)

rash or itching

persistent ringing or noise in the ears

The above side effects are usually mild.

If any of the following happen, tell your doctor immediately or go to Accident and Emergency at the nearest hospital:

heartburn or indigestion, which may be due to irritation of the oesophagus (food pipe)

severe diarrhoea, usually with blood and mucus, stomach pain and fever

bleeding or bruising more easily than normal

fast heart rate

severe blisters and bleeding in the lips, eyes, mouth, nose and genitals

signs of liver disease such as feeling generally unwell, fever, itching, yellowing of the skin and/or eyes, and dark coloured urine

passing little or no urine

joint pain, muscle tenderness or weakness

pain or difficulty in swallowing

severe sunburn that occurs more quickly than normal

severe skin reactions starting as painful red areas then large blisters and ends with peeling of layers of skin

signs of an allergic reaction such as skin rash, itching or hives; shortness of breath, wheezing or trouble breathing; swelling of the face, lips, tongue or other parts of the body.

The side effects listed above are serious and require medical attention.

However, these side effects are rare.

Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Other side effects not listed above may also occur in some people.

After finishing Doxylin

See your doctor immediately if you notice any of the following, particularly if they occur several weeks after stopping treatment with Doxylin:

watery and severe diarrhoea, which may also be bloody

severe stomach cramps

fever in combination with one or both of the above.

These are rare but serious side effects. You may need urgent medical attention or hospitalisation. Doxylin can cause some bacteria that are normally harmless and present in the bowel to multiply and cause the above symptoms.

You may have a serious condition affecting your bowels. Therefore you may need urgent medical attention.

Do not take any medicine for diarrhoea without first checking with your doctor.

After taking it

Storage

Keep your tablets in the pack until it is time to take them.

If you take the tablets out of the pack they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 30°C.

Do not store Doxylin or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Disposal

If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.

Product description

What it looks like

Doxylin is available in two strengths:

Doxylin 50 mg - round, yellow tablet marked "DE" over "50" one side and "G" on the reverse.

Doxylin 100 mg - round, yellow tablet marked "DE" over "100" one side and "G" on the reverse.

Doxylin 50 is available in bottles of 25 tablets.

Doxylin 100 is available in blister packs of 7 and 21 tablets.

Ingredients

The active ingredient in Doxylin tablets is doxycycline (as hydrochloride).

Doxylin 50 tablets contain 50 mg of doxycycline and Doxylin 100 tablets contain 100 mg of doxycycline.

Doxylin tablets also contain the following inactive ingredients:

pregelatinised maize starch

colloidal anhydrous silica

About Us, Alzen

Main menu

About Us

The Alzen Family consists of Brad (dad) on rhythm guitar, Denise (mom) on harmonica, and six children: Isaac on upright bass, Lucas on whiz-bang, AnaLise on mandolin, fiddle & guitar, and Tessa on fiddle, banjo & dobro. Jacob is learning the bass and Jonas isn’t sure yet what instrument suits him best. Each family member sings, and the variation from Isaac’s deep bass voice to Tessa’s sweet alto to AnaLise’s powerful soprano provides great variety and interest in their music.

The Alzen Family lives on small acreage in northwestern Wisconsin, where they have tasted some country living, complete with wood-burning stoves, and a flock of egg-laying hens. It seems fitting that their adventure in old-time music followed their move to the country. The Alzen’s strive to live life a little more like the “old days”. Television has been mostly replaced by reading, playing board games & sports, learning foreign languages, fishing & hunting and, of course, making music together.

The Alzens are grateful for the opportunity to sing and share in front of people. Their chief aim is to share the hope they have in Jesus Christ, and His saving grace..

Upcoming Dates

Zemtard, Zemtard

diltiazem hydrochloride

(redirected from Zemtard )

diltiazem hydrochloride

Adizem (UK), Angitil (UK), Apo-Diltiaz (CA), Apo-Diltiazem (CA), Calcicard (UK), Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Dilacor-XR, Dilcardia (UK), Dilt-CD, Dilt-XR, Diltia XT, Diltzac, Dilzem (UK), Disogram (UK), Gen-Diltiazem (CA), Med-Diltiazem (CA), Novo-Diltazem (CA), Nu-Diltiaz (CA), Optil (UK), Ratio-Diltiazem (CA), Sandoz Diltiazem (CA), Slozem (UK), Taztia XT, Tiazac, Tildiem (UK), Viazem (UK), Zemtard (UK)

Pharmacologic class: Calcium channel blocker

Therapeutic class: Antianginal, antiarrhythmic (class IV), antihypertensive

Pregnancy risk category C

Action

Inhibits calcium from entering myocardial and vascular smooth-muscle cells, thereby depressing myocardial and smooth-muscle contraction and decreasing impulse formation and conduction velocity. As a result, systolic and diastolic pressures decrease.

Availability

Capsules (extended-release, sustained-release ): 60 mg, 90 mg, 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg

Injection: 5 mg/ml in 10-ml vials, 100-mg Monovial

Tablets: 30 mg, 60 mg, 90 mg, 120 mg

⊘ Indications and dosages

➣ Angina pectoris and vasospastic (Prinzmetal's) angina; hypertension; supraventricular tachyarrhythmias; atrial flutter or fibrillation

Adults: 30 to 90 mg P. O. three to four times daily (tablets), or 60 to 120 mg P. O. b. i.d. (sustained-release), or 180 to 240 mg P. O. once daily (extended-release), adjusted after 14 days as needed, up to a total daily dosage of 360 mg. Or 0.25 mg/kg by I. V. bolus over 2 minutes; if response is inadequate after 15 minutes, may give 0.35 mg/kg over 2 minutes; may follow with continuous I. V. infusion at 10 mg/hour (at a range of 5 to 15 mg/hour) for up to 24 hours.

Dosage adjustment

• Severe hepatic or renal impairment • Elderly patients

Off-label uses

• Unstable angina, coronary artery bypass graft surgery • Tardive dyskinesia • Migraine • Hyperthyroidism • Raynaud's phenomenon

Contraindications

• Hypersensitivity to drug • Atrial flutter or fibrillation associated with shortened refractory period (Wolff-Parkinson-White syndrome, with I. V. use) • Recent myocardial infarction or pulmonary congestion • Cardiogenic shock, concurrent I. V. beta-blocker therapy, ventricular tachycardia, neonates (with I. V. use, because of benzyl alcohol in syringe formulation) • Sick sinus syndrome, second - or third-degree atrioventricular block (except in patients with ventricular pacemakers) • Hypotension (systolic pressure below 90 mm Hg)

Precautions

Use cautiously in: • severe hepatic or renal impairment, heart failure • history of serious ventricular arrhythmias • concurrent use of I. V. diltiazem and I. V. beta blockers • elderly patients • pregnant or breastfeeding patients • children (safety not established).

Administration

• When giving I. V. dilute in dextrose 5% in water or normal saline solution. • Give I. V. bolus dose over 2 minutes; a second bolus may be given after 15 minutes. • Administer continuous I. V. infusion at a rate of 5 to 15 mg/hour.

☞ When giving by continuous I. V. infusion, make sure emergency equipment is available and that patient has continuous ECG monitoring with frequent blood pressure monitoring. • Don't crush tablets or sustained-release capsules; they must be swallowed whole. • Withhold dose if systolic blood pressure falls below 90 mm Hg, diastolic pressure is below 60 mm Hg, or apical pulse is slower than 60 beats/minute.

Adverse reactions

CNS: headache, abnormal dreams, anxiety, confusion, dizziness, drowsiness, nervousness, psychiatric disturbances, asthenia, paresthesia, syncope, tremor

CV: peripheral edema, bradycardia, chest pain, hypotension, palpitations, tachycardia, arrhythmias, heart failure

EENT: blurred vision, tinnitus, epistaxis

GI: nausea, vomiting, diarrhea, constipation, dyspepsia, dry mouth

GU: urinary frequency, dysuria, nocturia, polyuria, gynecomastia, sexual dysfunction

Hematologic: anemia, leukopenia, thrombocytopenia

Musculoskeletal: joint stiffness, muscle cramps

Respiratory: cough, dyspnea

Skin: rash, dermatitis, flushing, diaphoresis, photosensitivity, pruritus, urticaria, erythema multiforme

Other: unpleasant taste, gingival hyperplasia, weight gain, decreased appetite, Stevens-Johnson syndrome

Interactions

Drug-drug. Beta-adrenergic blockers, digoxin, disopyramide, phenytoin: bradycardia, conduction defects, heart failure

Carbamazepine, cyclosporine, quinidine: decreased diltiazem metabolism, increased risk of toxicity

Cimetidine, ranitidine: increased blood level and effects of diltiazem

Fentanyl, nitrates, other antihypertensives, quinidine: additive hypotension

HMG-CoA reductase inhibitors, imipramine, sirolimus, tacrolimus: increased blood levels of these drugs

Lithium: decreased lithium blood level, reduced antimanic control

Nonsteroidal anti-inflammatory drugs: decreased antihypertensive effect of diltiazem

Theophylline: increased theophylline effects

Drug-diagnostic tests. Hepatic enzymes: increased levels

Drug-food. Grapefruit juice: increased blood level and effects of diltiazem

Drug-behaviors. Acute alcohol ingestion: additive hypotension

Patient monitoring

• Check blood pressure and ECG before starting therapy, and monitor closely during dosage adjustment period. Withhold dose if systolic pressure is below 90 mm Hg.

☞ Monitor for signs and symptoms of heart failure and worsening arrhythmias. • Supervise patient during ambulation.

Patient teaching

• Instruct patient to swallow extended-release capsules whole and not to crush or chew them. • Advise patient to change position slowly to minimize light-headedness and dizziness. • Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness. • As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, foods, and behaviors mentioned above.

Link to this page:

Brufen Retard 800 Mg Prolonged Release Tablets, Berifen

BRUFEN RETARD 800 MG PROLONGED RELEASE TABLETS

Transcript

Patient Information Leaflet

Brufen® Retard 800 mg Prolonged Release Tablets (ibuprofen) IMPORTANT INFORMATION Read all of this leaflet carefully before you start taking this medicine ? Keep this leaflet as you may need to read it again ? The name of this medicine is Brufen® Retard 800 mg Prolonged Release Tablets but will be referred to as Brufen Retard throughout the remainder of this leaflet ? This leaflet provides a summary of the information currently available about Brufen Retard ? For further information or advice ask your doctor or pharmacist ? This medicine is for you only and should never be given to anyone else, even if they appear to have the same symptoms as you ? Tell your doctor or pharmacist if you experience any side effects Leaflet contents: 1) What is Brufen Retard & what is it used for? 2) What should you know before taking Brufen Retard? 3) How should you take Brufen Retard? 4) Possible side effects of Brufen Retard. 5) How should you store Brufen Retard? 6) Further information about Brufen Retard. 1) WHAT IS BRUFEN RETARD & WHAT IS IT IS USED FOR? Brufen Retard belongs to a group of medicines called anti-inflammatory pain killers. They can be used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis (including juvenile rheumatoid arthritis or Still’s disease), arthritis of the spine (ankylosing spondylitis), swollen joints, frozen shoulder, bursitis, tendinitis, tenosynovitis, lower back pain, sprains and strains. Brufen Retard can also be used to treat other painful conditions such as toothache, pain after operations, period pain and headache, including migraine. The active ingredient in Brufen Retard is ibuprofen and each tablet contains 800 mg in a sustained-release formulation. This is designed to release ibuprofen gradually into your blood stream throughout the day. 2) WHAT SHOULD YOU KNOW BEFORE TAKING BRUFEN RETARD? If the answer to any of the following questions is ‘YES’ please tell your doctor or pharmacist BEFORE taking any Brufen Retard tablets: ? Are you pregnant or planning to become pregnant, or are you breastfeeding? Brufen Retard may make it more difficult to become pregnant. You should inform your doctor if you are planning to become pregnant or if you have problems becoming pregnant. ? Are you sensitive (allergic) to any of the ingredients in the tablets? These are listed in Section 6. ? Do you have, or have you previously had, a stomach ulcer or other gastric complaint? Do not take Brufen Retard if you currently have a peptic ulcer (ulcer in your stomach or duodenum) or bleeding in your stomach, or have had two or more episodes of peptic ulcers, stomach bleeding or perforation in the past. ? Do you have a condition which increases your tendency to bleeding? ? Do you suffer from asthma or have you ever had an allergic reaction or suffered from wheezing after taking ibuprofen, aspirin or other antiinflammatory pain killers? ? Do you suffer from liver or kidney disease? ? Do you suffer from heart disease? Medicines such as Brufen Retard may be associated with a small increased risk of heart attack (myocardial infarction) or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment. If you have heart problems, previous stroke or think that you might be at risk of these conditions (e. g. if you have high blood pressure, diabetes, high cholesterol or are a smoker) you should discuss your treatment with your doctor or pharmacist. ? Do you have systemic lupus erythematosus (SLE, sometimes known as lupus) or a connective tissue disease (autoimmune diseases affecting connective tissue)?

Can you take Brufen Retard with other medicines? Some medicines that are anti-coagulants (i. e. thin blood/prevent clotting e. g. aspirin/acetylsalicyclic acid, warfarin, ticlodipine), some medicines that reduce high blood pressure (ACE-inhibitors such as captopril, betablockers such as atenolol, or angiotensin-II receptor antagonists such as losartan) and other medicines may affect or be affected by treatment with ibuprofen. You should therefore always seek the advice of your doctor or pharmacist before you use ibuprofen with other medicines. In particular you should tell your doctor or pharmacist if you are taking any of the following medicines in addition to those mentioned above: ? diuretics (water tablets) ? cardiac glycosides, such as digoxin, used to treat heart conditions ? lithium ? zidovudine (an anti-viral drug) ? steroids (used in the treatment of inflammatory conditions) ? methotrexate (used to treat certain cancers) ? medicines known as immunosuppressants such as ciclosporin and tacrolimus (used to dampen down your immune response) ? medicines known as selective serotonin reuptake inhibitors (SSRIs), used for the treatment of depression ? antibiotics called quinolones such as ciprofloxacin ? aminoglycosides (a type of antibiotic) ? mifepristone ? any other ibuprofen preparations, such as those you can buy without a prescription ? any other anti-inflammatory pain killer, including aspirin ? cholestyramine (a drug used to lower cholesterol) ? medicines known as sulphonylureas such as glibenclamide (used to treat diabetes) ? voriconazole or fluconazole (types of anti-fungal drugs) ? Gingko biloba herbal medicine (there is a chance you may bleed more easily if you are taking this with ibuprofen). Pregnancy and breast-feeding: The use of Brufen Retard whilst pregnant or breast-feeding should be avoided. Brufen Retard should not be used in late (the last three months) of pregnancy and should only be taken in the first six months of pregnancy on the advice of your doctor. Driving and Using Machines: Brufen Retard may make you feel dizzy or drowsy. If the tablets affect you in this way do not drive, operate machinery or do anything that requires you to be alert. 3) HOW SHOULD YOU TAKE BRUFEN RETARD? ALWAYS take Brufen Retard exactly as your doctor has told you. If you are not sure refer to the label on the carton or check with your doctor or pharmacist. TAKE YOUR BRUFEN RETARD TABLETS with a glass of water. You should swallow the tablets whole without chewing, breaking, crushing or sucking on them to help prevent feeling discomfort in the mouth or irritation in the throat. The tablets are best taken in the early evening, well before retiring to bed. Take your Brufen Retard with or after food. Your dosage will depend on what you are being treated for, the usual dose is two tablets taken as a single dose each day, preferably in the evening. In severe or acute conditions, your doctor may prescribe one extra tablet to be taken each morning in addition to the usual dose. Brufen Retard is NOT suitable for children under 12 years of age. IF YOU TAKE MORE BRUFEN RETARD THAN PRESCRIBED (AN OVERDOSE) you should contact a doctor or go to the nearest hospital casualty department IMMEDIATELY taking your tablets with you. IF YOU FORGET TO TAKE YOUR BRUFEN RETARD TABLETS take them as soon as you remember, unless it is almost time for your next dose. If it is, do not take the missed dose at all. Never double up on a dose to make up for the one you have missed.

4) POSSIBLE SIDE EFFECTS OF BRUFEN RETARD As with all medicines, Brufen Retard may cause side effects, although they are usually mild and not everyone will suffer from them. If any side effects become serious or if you notice any side effects that are not listed in this leaflet, please tell your doctor or pharmacist. You can minimise the risk of side effects by taking the least amount of tablets for the shortest amount of time necessary to control your symptoms. If you suffer from any of the following at any time during your treatment STOP TAKING Brufen Retard and seek immediate medical help: ? Severe headache, high temperature, stiffness of the neck or intolerance to bright light ? Pass blood in your faeces (stools/motions) ? Pass black tarry stools ? Vomit any blood or dark particles that look like coffee grounds. TELL YOUR DOCTOR AND STOP TAKING THE TABLETS IF YOU EXPERIENCE: ? Unexplained stomach pain or other abnormal stomach symptoms, indigestion, heartburn, feeling sick and/or vomiting ? Unexplained wheezing, shortness of breath, skin rash, itching or bruising ? Yellowing of the eyes and/or skin ? Severe sore throat with high fever ? Blurred or disturbed vision or seeing/hearing strange things ? Fluid retention (e. g. swollen ankles). Medicines such as Brufen Retard have been associated with a small increased risk of heart attack (myocardial infarction) or stroke. Blood disorders, kidney problems, liver problems or severe skin reactions may occur rarely with ibuprofen. Very rarely Brufen Retard may cause aseptic meningitis (inflammation of the protective membrane surrounding the brain). Other side effects may include headache, hallucinations, dizziness, tingling of hands and feet, ringing in the ears, depression, confusion, difficulty sleeping, anxiety, impaired hearing, diarrhoea, constipation, flatulence (wind), unexpected sensitivity of the skin to the sun, tiredness, malaise, mood swings and swelling and irritation inside the nose. Brufen Retard has also been shown to sometimes worsen the symptoms of Crohn’s disease or colitis. 5) HOW SHOULD YOU STORE BRUFEN RETARD? ? Your tablets should be stored at room temperature (do not store above 25°C). ? They should be kept in a safe place out of the sight and reach of children, your medicine could harm them. ? Store in the original packaging in order to protect from moisture. ? Do not use this medicine after its expiry date. The expiry date refers to the last day of that month. ? If your medicine becomes discoloured or shows any sign of deterioration, return them to your pharmacist. ? If your doctor decides to stop your treatment, return any leftover tablets to your pharmacist. Only keep them if your doctor tells you to. ? Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. 6) FURTHER INFORMATION ABOUT BRUFEN RETARD What Brufen Retard contains Each tablet contains the active ingredient ibuprofen 800 mg in a prolonged release formulation. The other ingredients are: colloidal anhydrous silica, povidone, stearic acid, xanthan gum, hypromellose, talc, opaspray white M-1-7111B (containing: hypromellose, titanium dioxide) What Brufen Retard looks like and contents of the pack Brufen Retard are white pillow-shaped, film-coated, prolonged release tablets. They come in PVC/PVDC/aluminium blister strips in a printed carton. Each pack contains 60 tablets.

Manufacturer FAMAR S. A. 7 Anthousas Ave, 153 44 Anthousa Attiki, Greece Abbott GmbH & Co. KG, Knollstrasse 50, 67061 Ludwigshafen, Germany Procured from within the EU by the Product Licence holder MPT Pharma Ltd, Westgate Business Park, Unit 5-7 Tintagel Way, Aldridge, Walsall, WS9 8ER, UK Repackaged by XXXXXXXXXXXXXXXXXXXXXXXXXXXX PL: 33532/0412

Leaflet date: 07 February 2013 Leaflet code: XXXXXXXXXX Brufen® is a registered trademark of XXXXXXXXXXXXXXXXXXXX.

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Anacin (Aspirin, Acetolit

Product Description

Anacin prescribed for treatment of pain, with different nature of appearance (muscle aches, headache, toothache, arthritis and rheumatism, menstrual cramps, pain and fever of common cold) and for reducing of the tendency of blood clots. This medication is a combination of stimulant and salicylate. His mechanism of working is the the following: it blocks several different chemical processes within the body that cause pain, inflammation and fever.

Consult with your doctor about dosage. Anacin may cause stomach upset, so better take it with food to reduce stomach irritation. Use the medicine with a full glass of water and avoid a recumbent position during next 30 minutes.

Before to start treatment with Anacin consult with your doctor or pharmacist if you have: allergy to food, medicines, or other substances, asthma, bleeding or clotting problems, kidney or liver problems, stomach and intestinal problems, growths in the nose, heart problems, upset stomach, heartburn, stomach pain, hives, flu, chickenpox; anxiety, trouble sleeping or heart problems; if you have a plan to become pregnant, or you are pregnant, or you're breastfeeding; if you are taking any prescribed and not prescribed medicine, herbal products, or dietary supplement; vitamin K deficiency; alcoholism or if you consume 3 or more alcohol drinks per day. Children with a stroke, a weaken blood vessel or bleeding in the brain, Kawasaki syndrome or rheumatic disease shouldn't use Anacin.

Patients with an allergy to any ingredient of Anacin, or who has a severe allergic reaction such as rush, hives, breathing difficulties, dizziness to aspirin, tartrazine or non-steroidal anti-inflammatory drug (NSAID), children or teenagers with flu or chickenpox, patients with bleeding problems such as hemophilia, Von Willebrand disease, low blood platelets, or active severe bleeding and patients, who are taking anticoagulants or methotrexate - shouldn't use Anacin.

Possible side effects

Possible side effects are the following: dizziness, irritability, nausea, nervousness, upset stomach. The severe side effects include allergic reactions such as rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; confusion; diarrhea; drowsiness; severe or persistent dizziness hearing loss; ringing in the ears; severe or persistent stomach pain or heartburn; black or bloody stools; shakiness; trouble sleeping; vomiting. In case if you think that you feel some symptoms of side effects you should call for medical help immediately.

You must consult with your doctor about interaction between Anacin and the following drugs: angiotensin-converting enzyme (ACE) inhibitors (enalapril), probenecid, or sulfinpyrazone because their effectiveness may be decreased by Anacin; carbonic anhydrase inhibitors (acetazolamide) because they may decrease Anacin's effectiveness; insulin or oral anti-diabetics because the risk of their side effects, including low blood sugar may be increased by Anacin; anticoagulants ( heparin, warfarin), clopidogrel, or NSAIDs (ibuprofen, celecoxib) because the risk of their side effects, including risk of bleeding, may be increased by Anacin; quinolones (ciprofloxacin).

Never take more than prescribed dose, even if you missed the one. Try to take it as soon as possible. Or, if it's too late, just skip it and take your usually dose next day in the same regularly time.

In case if you think that you could be overdosed by Anacin you should call for medical help immediately. Symptoms of Anacin overdose are following: agitation; anxiety; confusion; fever; hearing loss; lethargy; lightheadedness, especially upon standing; muscle twitching; nausea; rapid breathing; rapid or irregular heartbeat; ringing in the ears; seizures; shortness of breath; stomach pain; trouble sleeping; vomiting. If you think that you overdosed Anacin, seek medical attention at once.

Store at room temperature between 68-77 F (20-25 C), in a dark and dry place. Save it from children and pets. Watch the expiration date!

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.

Customers Who Bought This Product Also Bought:

Kemicetine Succinate Injection, Kemicetine

KEMICETINE SUCCINATE INJECTION

Chloramphenicol sodium succinate equivalent to 1 g chloramphenicol Powder for Solution for Injection

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Keep this leaflet. You may need to read it again. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours. If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet:

This medicine contains chloramphenicol sodium succinate, which is an antibiotic used to treat severe infections such as typhoid and meningitis, and should only be used when other antibiotics do not help or are unsuitable. It is also used when oral chloramphenicol cannot be used or when higher amounts of the medicine is needed in the blood. Chloramphenicol prevents bacteria making an essential nutrient required for growth and multiplication. In time, the number of bacteria are reduced and the infection is controlled, so that treatment can be continued using a more gentle antibiotic. You must talk to a doctor if you do not feel better or if you feel worse.

2. What you need to know before you are given Kemicetine Succinate Injection

Do not use Kemicetine Succinate Injection: • If you have had an allergic reaction (e. g. rash, wheezing) to chloramphenicol before. • If you are pregnant, or are breast-feeding.

Warnings and precautions:

Talk to your doctor or pharmacist: • If you have a history of kidney or liver disease. • If you are already taking any other medicines which may also cause bone marrow depression. • If you have a cold, viral influenza, throat infection and before using this medicine to prevent bacterial infections. • If you have recently been or are about to be vaccinated. This medicine is associated with various forms of anaemia

(a decrease in red blood cells, white blood cells and platelets), which in turn leads to a loss of immunity and can progress into leukaemia. It should only be prescribed if less toxic antibiotics are not available. New born babies should be treated with care to avoid Grey Syndrome, which is a serious condition arising from excessive toxic chloramphenicol metabolites. Treatment should be terminated as soon as symptoms are identified. There is a risk of over-growth of non-susceptible organisms, which can lead to severe diarrhoea up to a few months after this medicine is given to the patient.

Healthcare Professional Information Leaflet

Kemicetine® Succinate Injection

Other medicines and Kemicetine Succinate Injection:

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. The following medicines interact with Kemicetine Succinate Injection, which affects the way that one or the other medicine works: • anticoagulants of the coumarin-type (to thin your blood or stop it clotting), antidiabetic agents (e. g. tolbutamide), anti-epileptic agents (e. g. phenytoin and phenobarbital) or rifampicin (an antibiotic).

Pregnancy and breast-feeding

If you are pregnant, breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before being given this medicine.

1. What Kemicetine Succinate Injection is and what it is used for 2. What you need to know before you are given Kemicetine Succinate Injection 3. How Kemicetine Succinate Injection is given to you 4. Possible side effects 5. How to store Kemicetine Succinate Injection 6. Contents of the pack and other information

1. What Kemicetine Succinate Injection is and what is it used for

Package leaflet: Information for the patient

Driving and using machines

No effect on the ability to drive or use machinery is expected with Kemicetine Succinate Injection.

Chloramphenicol sodium succinate Equivalent to 1 g chloramphenicol Powder for Solution for Injection

After parenteral administration chloramphenicol is rapidly released from chloramphenicol sodium succinate. Kemicetine (chloramphenicol) is a broad spectrum antibiotic and is active against many gram-positive organisms and gram-negative organisms, spirillae and rickettsia. It acts by interfering with bacterial protein synthesis. Chloramphenicol is widely distributed in body tissues and fluids and enters the cerebrospinal fluid. Chloramphenicol sodium succinate, free chloramphenicol and metabolites are excreted in the urine. After intravenous administration of chloramphenicol succinate every 6 hours elimination half lives were 4.03 hours for chloramphenicol and 2.65 hours for chloramphenicol succinate. After intravenous chloramphenicol sodium succinate, steady state peak concentrations were reached on average 18.0 minutes after cessation of the infusion. In infants and children aged 3 days to 16 years the apparent half-life was extremely variable ranging from 1.7 to 12.0 hours. Indications Kemicetine Succinate should not be used for trivial infections due to the possibility of severe blood dyscrasias which may prove fatal. Kemicetine succinate is indicated for typhoid, meningitis caused by H. influenzae and other serious infections caused by bacteria susceptible to chloramphenicol. It is also indicated wherever chloramphenicol is deemed the antibiotic of choice and oral administration is not possible, or where higher than usual blood concentrations are required. Dosage and administration Posology The dose administered and the concentration used is dependent on the severity of the infection. The recommended standard dosage is as follows:

Adults: The equivalent of 1 g of chloramphenicol every 6-8 hours. Elderly: The usual adult dosage should be given subject to normal hepatic and renal function. Children: The equivalent of 50 mg/kg chloramphenicol, according to body weight, daily in divided doses every 6 hours (this dose should not be exceeded). The patient should be carefully observed for signs of toxicity. Premature Infants and Neonates: 25 mg/kg in divided doses. In exceptional cases, such as patients with septicaemia or meningitis, dosage schedule up to 100 mg/kg/day may be prescribed. However, these high doses should be decreased as soon as clinically indicated. To prevent relapses, treatment should be continued after the temperature has returned to normal for 4 days in rickettsial diseases and for 8-10 days in typhoid fever. The 10 % solution should be given by intravenous injection over a period of about a minute, or in a large volume of fluid, by slow intravenous infusion. The concurrent administration of intravenous Kemicetine succinate with topical treatment has been found to be very effective in the treatment of osteomyelitic foci, abscesses, empyema and skin and urinary infections. Method of administration To be given by intravenous or intramuscular injection. In order to ensure rapid attainment of high blood levels, Kemicetine Succinate Injection is best administered by intravenous injection. Where this is not possible, however, intramuscular administration may be used, although it should be borne in mind that absorption may be slow and unpredictable. The injection should be reconstituted with water for injections, sodium chloride injection, or dextrose injection 5 %. The following dilution table may be useful for the administration of a proportion of the contents of a vial: Concentration Solution Volume of diluent to Total volume strength be added after dilution 40% 400 mg/ml 1.7 ml 2.5 ml 25% 250 mg/ml 3.2 ml 4.0 ml 20% 200 mg/ml 4.2 ml 5.0 ml

Contraindications and warnings Kemicetine Succinate is contraindicated in patients with a previous history of sensitivity and/or toxic reactions to chloramphenicol. It is also contraindicated in pregnancy and whilst breast feeding. Kemicetine Succinate is to be administered only under the direction of a medical practitioner. It should be reserved for serious infections caused by organisms susceptible to its antimicrobial effects when less toxic antibiotics are ineffective or contraindicated. However, chloramphenicol may be chosen to initiate antibiotic therapy based on the clinical impression. In vitro sensitivity tests should be performed concurrently so that the drug may be discontinued as soon as possible if a less toxic antibiotic is indicated by the results of such tests. The decision to continue use of chloramphenicol, rather than another antibiotic when both are suggested by in vitro studies to be effective against a specific pathogen, should be based upon severity of the infection, susceptibility of the pathogen to the various antimicrobial drugs, and the efficacy of the various drugs in the infection. Bone marrow depression and blood disorders Serious and fatal blood dyscrasias (aplastic anaemia, hypoplastic anaemia, thrombocytopenia, granulocytopenia, and bone marrow depression) are known to occur after the administration of chloramphenicol. In addition, there have been reports of aplastic anaemia attributed to chloramphenicol, which later resulted in leukaemia. Blood dyscrasias have occurred after both short-term and prolonged therapy with this drug. Chloramphenicol must not be used in the treatment of any infection for which a less toxic antibiotic is available. Patient monitoring Because of its toxic nature it is important to monitor serum levels of this antibiotic particularly in new-born and premature infants, in the elderly, in patients with renal or hepatic disease and in those receiving other drugs with which chloramphenicol may interact. It is essential that adequate haematologic functions be closely monitored during treatment with chloramphenicol. While haematologic determinations may detect early peripheral haematologic changes, such as leucopoenia, reticulocytopenia, or granulocytopenia, before they become irreversible, such determinations cannot be relied on to detect bone marrow depression prior to the development of aplastic anaemia.

It is desirable that patients be hospitalized during therapy, so that appropriate laboratory determinations and clinical observations can be made. Baseline haematologic determinations should be made and determinations repeated approximately every two days during therapy. The drug should be discontinued upon appearance of reticulocytopenia, leucopoenia, thrombocytopenia, anaemia, or any other haematologic findings attributable to chloramphenicol. However, such determinations do not exclude the possible later appearance of the irreversible type of bone marrow depression. Repeated courses of the drug should be avoided if at all possible. Treatment should not be continued longer than required to produce a cure with little or no risk of relapse of the disease. Concurrent therapy with other drugs that may cause bone marrow depression should be avoided. The following may become apparent after chloramphenicol treatment: dryness of the mouth, nausea and vomiting, diarrhoea, urticaria, optic neuritis with blurring or temporary loss of vision, peripheral neuritis, headache and depression. Chloramphenicol has been shown to interact with, and enhance the effects of coumarin anticoagulants, some hypoglycaemic agents (e. g. tolbutamide) and phenytoin. When given concurrently, a dose reduction of these agents may, therefore, be necessary. Plasma concentration of chloramphenicol may be reduced with concomitant usage of phenobarbital and rifampicin. Chloramphenicol may impede the development of immunity and should therefore not be given during active immunisation. Hepatic or Renal Impairment Excessive chloramphenicol serum levels may result from administration of the recommended dose to patients with impaired liver or kidney function, including that due to immature metabolic processes in the infant. Dosage should be adjusted accordingly or, preferably, the serum concentration should be determined at appropriate intervals. Grey syndrome in infants and neonates Precaution should be used in therapy of premature and full-term neonates to avoid “Grey Syndrome” toxicity. Serum drug levels should be carefully monitored during therapy of the neonate (newborn infant). Toxic reactions, including fatalities, have occurred in premature infants and neonates. The signs and symptoms associated with these reactions

have been referred to as the “Grey Syndrome”. Although “Grey Syndrome” has been reported in neonates born to mothers after having received chloramphenicol during labour, in most cases therapy with chloramphenicol has been instituted within the first 48 hours of life. The following summarizes the clinical and laboratory determinations that have been made on these patients. Symptoms first appeared after 3 to 4 days of continued treatment with high doses of chloramphenicol. The symptoms appeared in the following order: abdominal distension with or without emesis, progressive pallid cyanosis, vasomotor collapse, frequently accompanied by irregular respiration, death within a few hours of onset of these symptoms. The progression of symptoms from onset to death was accelerated with higher dose schedules. Serum drug levels revealed unusually high concentrations of chloramphenicol (over 90 mcg/mL after repeated doses). Termination of therapy upon early evidence of the associated symptomatology frequently reversed the process with complete recovery following. General Chloramphenicol must not be used in the treatment of trivial infections or where it is not indicated, as in colds, viral influenza, infections of the throat or as a prophylactic agent to prevent bacterial infections. Superinfections The use of chloramphenicol, as with other antibiotics, may result in an overgrowth of nonsusceptible organisms, including fungi. If infections caused by nonsusceptible organisms appear during therapy, appropriate measures should be taken. Clostridium difficile associated diarrhoea (CDAD) has been reported with use of nearly all antibacterial agents, including chloramphenicol, and may range in severity from mild diarrhoea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C difficile. C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and

3. How Kemicetine Succinate Injection is given to you

may require colectomy. CDAD must be considered in all patients who present with diarrhoea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Pharmaceutical precautions Keep container in the outer carton. Package quantities Individual vials containing Kemicetine Succinate equivalent to 1 g chloramphenicol. POM PL 00057/1001 Keep all medicines out of the sight and reach of children. Manufactured by: Actavis Italy S. p.A, 10 Via Pasteur, Nerviano, Milan, Italy. Marketing Authorisation Holder: Pfizer Limited Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK Further information is available to the medical and allied professions on request from: Medical Information at Pfizer Limited, Walton Oaks, Tadworth, Surrey, KT20 7NS, UK. Tel: 01304 616161 This leaflet was last revised in 05/2014 Ref: KM 14_0

Kemicetine Succinate will be made into a solution and be given to you by injection into a vein, or into a muscle under the direction of a medical practitioner. Your doctor will prescribe the required amount (the dose). The dose is decided by taking into account the severity of your condition.

The usual dosage for adults is; 1g of chloramphenicol every 6-8 hours.

Use in children and adolescents:

The usual dose for children is; 50 mg/kg of chloramphenicol daily in divided doses every 6 hours (no more than this should be given); and 25 mg/kg daily in divided equal doses every 6 hours in new-born and premature infants. The doctor may give you more in certain cases e. g. if you have septicaemia or meningitis (100 mg/kg/day), but should then be decreased as soon as appropriate. Your doctor will decide how long you need to be treated for. During treatment your doctor will carry out blood tests to check that: • Your blood is functioning properly as Kemicetine Succinate Injection can damage your blood cells. • Your liver and kidneys are functioning properly as Kemicetine Succinate Injection may affect these organs.

If you are given more Kemicetine Succinate Injection than you should

In the case of serious overdosage, charcoal haemoperfusion may be effective in removing chloramphenicol from your blood.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Tell your doctor immediately if any of the following side effects occur: • Severe allergic reaction e. g. red raised areas on your skin which may look like spots or be several inches across, which cause itchiness. • Grey Syndrome – usually in new-born or premature infants, where the skin appears grey, and the infant is listless and weak. • White blood cell counts (which fight infection) can also drop, increasing the chance of infections, bruising and fever. Anaemia (a low red blood cell count) that can leave you feeling tired and lethargic. Other side effects may occur, but, the frequency cannot be estimated from the available data: • Dry mouth. • Nausea (feeling sick), vomiting (being sick) and diarrhoea. • Headache. • Depression. • Inflammation or damage to the nerves causing numbness, tingling, pain or muscle weakness. • Blurring, inflammation or temporary loss of vision. • Chloramphenicol may slow down development of immunity, and you may develop infections more frequently, which are difficult to fight off.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www. mhra. gov. uk/yellowcard.

REASON FOR REVISION: Change of name to Pfizer on leaflet - this replaces the leaflet component on PAR 3020 which has now been removed due to the EC now superceded by changes approved on PAR 3502. this PAR contains the most recent approved leaflet with annotated changes to Pfizer name. Mock up is required by 25th May 2014 to submit. expected approval will be July 2014 and once approved by UK agency one production PAR will be created for all components

Description KEMICETINE Market UK Supplier No KEM-GB-01 Perigord No 229374 Barcode No N/A Pages 1 of 1

Proof No 01 Component Leaflet Colour Bar Positions 1, 6, 10 Drawing No N/A ITF Code (23%) FPO

Dimensions 124 x 480 mm - Image Prints @ 100% Notes N/A Colours 01 Supplier Actavis - Nerviano Smallest Font Used Body Text: 8.5 pt PAR Number PAR-2014-0004498

By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Kemicetine Succinate Injection

Your medicine should not be used after the expiry date given on the vial after EXP. The expiry date refers to the last day of that month Keep container in the outer carton. Keep this medicine out of the sight and reach of children.

6. Contents of the pack and other information What Kemicetine Succinate Injection contains:

The active substance is Chloramphenicol Sodium Succinate. There are no other ingredients found in Kemicetine Succinate Injection.

What Kemicetine Succinate Injection looks like and contents of the pack

Kemicetine Succinate Injection is available as single glass vials. Each vial contains a freeze-dried powder containing the equivalent of 1 g chloramphenicol. Marketing Authorisation Pfizer Limited Holder: Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK Manufacturer:

Actavis Italy S. p.A, 10 Via Pasteur, Nerviano, Milan, Italy. For further information on your medicine, contact Medical Information at Pfizer Limited, Walton Oaks, Dorking Road, Tadworth, Surrey, KT20 7NS. Tel: 01304 616161. This leaflet was last revised in 05/2014 Ref: KM 14_0

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Aggrenox (Aspirin, Extended-Release Dipyridamole Capsules) Side Effects, Interactions, Warning, Dosa

DRUG DESCRIPTION

AGGRENOX is a combination antiplatelet agent intended for oral administration. Each hard gelatin capsule contains 200 mg dipyridamole in an extended-release form and 25 mg aspirin, as an immediate-release sugar-coated tablet. In addition, each capsule contains the following inactive ingredients: acacia, aluminum stearate, colloidal silicon dioxide, corn starch, dimethicone, hypromellose, hypromellose phthalate, lactose monohydrate, methacrylic acid copolymer, microcrystalline cellulose, povidone, stearic acid, sucrose, talc, tartaric acid, titanium dioxide and triacetin.

Each capsule shell contains gelatin, red iron oxide and yellow iron oxide, titanium dioxide and water.

Dipyridamole

Dipyridamole is an antiplatelet agent chemically described as 2,2',2'',2'''-[(4,8-Dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol. It has the following structural formula:

Dipyridamole is an odorless yellow crystalline substance, having a bitter taste. It is soluble in dilute acids, methanol and chloroform. and is practically insoluble in water.

Aspirin

The antiplatelet agent aspirin (acetylsalicylic acid) is chemically known as benzoic acid, 2- (acetyloxy)-, and has the following structural formula:

Aspirin is an odorless white needle-like crystalline or powdery substance. When exposed to moisture, aspirin hydrolyzes into salicylic and acetic acids, and gives off a vinegary odor. It is highly lipid soluble and slightly soluble in water.

What are the possible side effects of aspirin and dipyridamole (Aggrenox)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

weakness or fainting;

black, bloody, or tarry stools;

coughing up blood or vomit that looks like coffee grounds;

severe nausea, vomiting, or stomach pain;

fever lasting longer than 3 days;

swelling, or pain lasting longer than 10 days; or

hearing.

What are the precautions when taking aspirin, extended-release dipyridamole capsules (Aggrenox)?

Before taking this medication, tell your doctor if you are allergic to dipyridamole; or to aspirin; or to other salicylates (such as choline salicylate); or to NSAIDs (such as ibuprofen, naproxen); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), bleeding problems (such as hemophilia, vitamin K deficiency, low platelets), low blood pressure (hypotension), heart problems (such as angina, heart attack), stomach problems (such as ulcers.

Last reviewed on RxList: 12/7/2015 This monograph has been modified to include the generic and brand name in many instances.

Niacin Drug Uses, Dosage - Side Effects, Nitrin Sr

Niacin

What is niacin?

Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. It is also present in many multiple vitamins and nutritional supplements.

Niacin is used to treat and prevent a lack of natural niacin in the body, and to lower cholesterol and triglycerides (types of fat) in the blood. It is also used to lower the risk of heart attack in people with high cholesterol who have already had a heart attack. It is sometimes used to treat coronary artery disease (also called atherosclerosis).

Niacin may also be used for purposes not listed in this medication guide.

Important information

You should not take this medication if you are allergic to niacin, or if you have severe liver disease, a stomach ulcer, or active bleeding.

Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take niacin. These effects should disappear over time as you keep taking the medication.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take this medicine.

Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Before taking this medicine

You should not take this medication if you are allergic to niacin, or if you have severe liver disease, a stomach ulcer, or active bleeding.

To make sure you can safely take niacin, tell your doctor if you have any of these other conditions:

liver or kidney disease;

heart disease or uncontrolled angina (chest pain);

a stomach ulcer;

a muscle disorder such as myasthenia gravis.

FDA pregnancy category C. Niacin may be harmful to an unborn baby when the medication is taken at doses to treat high cholesterol or other conditions. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Niacin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take niacin ?

Use niacin exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Niacin is sometimes taken at bedtime with a low-fat snack. Follow your doctor's instructions.

Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take niacin. These effects should disappear over time as you keep taking the medication.

Take niacin with a full glass of cold or cool water. Taking the medication with a hot drink may increase your risk of side effects such as flushing. Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Extended-release tablets and capsules contain higher strengths of the medicine than the regular tablets. Take only the dose that is correct for the type of niacin tablet or capsule you are using.

Niacin can cause you to have unusual results with certain medical tests (urine tests). Tell any doctor who treats you that you are using this medicine.

If you stop taking niacin for any length of time, talk with your doctor before starting the medication again. You may need to restart the medication at a lower dose.

While using niacin, you may need blood tests at your doctor's office. Your kidney or liver function may also need to be checked. Visit your doctor regularly.

Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Be sure to take the missed dose with food if you normally take your niacin dose with a meal or snack.

Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, dizziness, itching, vomiting, upset stomach, and flushing (warmth, redness, or tingly feeling).

What should I avoid?

Avoid drinking hot beverages shortly after taking niacin. Hot drinks can worsen the flushing effect (warmth, itching, redness, or tingly feeling under your skin).

Avoid drinking alcohol while taking niacin. Alcohol may increase your risk of liver damage, and can also worsen the flushing effects of this medicine.

Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take niacin.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Niacin side effects

Get emergency medical help if you have any of these signs of an allergic reaction to niacin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;

fast, pounding, or uneven heart beats;

feeling short of breath;

jaundice (yellowing of your skin or eyes); or

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

If you are diabetic, tell your doctor about any changes in your blood sugar levels.

Less serious side effects of niacin include:

warmth, redness, or tingly feeling under your skin;

itching, dry skin;

sweating or chills;

nausea, diarrhea, belching, gas;

muscle pain, leg cramps; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Niacin dosing information

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL):

Initial dose: 100 mg orally 3 times a day, with or after meals. Maintenance dose: 1 to 2 g orally 3 times a day, with or after meals. The maximum recommended dose is 6 g/day.

Extended Release (Niaspan): Initial dose: 500 mg orally once a day at bedtime after a low fat snack. Maximum recommended dose is 2 g/day.

Extended Release (Slo-Niacin): Initial dose: 250 to 750 mg orally once a day morning or evening.

Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):

Initial dose: 100 mg orally 3 times a day, with or after meals. Maintenance dose: 1 to 2 g orally 3 times a day, with or after meals. The maximum recommended dose is 6 g/day.

Extended Release (Niaspan): Initial dose: 500 mg orally once a day at bedtime after a low fat snack. Maximum recommended dose is 2 g/day.

Extended Release (Slo-Niacin): Initial dose: 250 to 750 mg orally once a day morning or evening.

Usual Adult Dose for Pellagra:

50 to 100 mg orally 3 to 4 times a day. The maximum recommended dose is 500 mg orally each day.

Usual Adult Dose for Niacin Deficiency:

10 to 20 mg orally once a day. Niacin may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products.

The maximum recommended dose is 100 mg orally each day.

Usual Pediatric Dose for Pellagra:

50 to 100 mg orally 3 times daily. Note: Some experts prefer niacinamide for treatment due to a more favorable side effect profile.

Usual Pediatric Dose for Niacin Deficiency:

Dosages are Recommended Daily Allowances (RDA): 1 to 5 months: 2 mg orally each day. 6 to 11 months: 3 mg orally each day. 1 to 3 years: 6 mg orally each day. 4 to 8 years: 8 mg orally each day. 9 to 13 years: 12 mg orally each day.

Males: 14 to 18 years: 16 mg orally each day.

Females: 14 to 18 years: 14 mg orally each day.

Niacin may also be administered parenterally as a component injectable multivitamin additives contained in parenteral nutrition products.

What other drugs will affect niacin?

Tell your doctor about all other cholesterol-lowering drugs you are taking with niacin, especially atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), or simvastatin (Zocor, Simcor, Vytorin, Juvisync).

Ask a doctor or pharmacist if it is safe for you to use niacin if you are also using any of the following drugs:

a blood thinner such as warfarin (Coumadin, Jantoven);

multivitamins or mineral supplements that contain niacin;

blood pressure or heart medications such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan); or

heart medications such as doxazosin (Cardura), isosorbide (Dilatrate, Imdur, Isordil, Monoket, Sorbitrate), nitroglycerin (Nitro-Bid, Nitro-Dur, Nitrostat), prazosin (Minipress), or terazosin (Hytrin).

This list is not complete and other drugs may interact with niacin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More about niacin

Consumer resources

Professional resources

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about niacin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 8.04. Revision Date: 2012-05-15, 8:52:03 AM.

Drug Status

Niacin

What is niacin?

Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. It is also present in many multiple vitamins and nutritional supplements.

Niacin is used to treat and prevent a lack of natural niacin in the body, and to lower cholesterol and triglycerides (types of fat) in the blood. It is also used to lower the risk of heart attack in people with high cholesterol who have already had a heart attack. It is sometimes used to treat coronary artery disease (also called atherosclerosis).

Niacin may also be used for purposes not listed in this medication guide.

Important information

You should not take this medication if you are allergic to niacin, or if you have severe liver disease, a stomach ulcer, or active bleeding.

Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take niacin. These effects should disappear over time as you keep taking the medication.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take this medicine.

Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Before taking this medicine

You should not take this medication if you are allergic to niacin, or if you have severe liver disease, a stomach ulcer, or active bleeding.

To make sure you can safely take niacin, tell your doctor if you have any of these other conditions:

liver or kidney disease;

heart disease or uncontrolled angina (chest pain);

a stomach ulcer;

a muscle disorder such as myasthenia gravis.

FDA pregnancy category C. Niacin may be harmful to an unborn baby when the medication is taken at doses to treat high cholesterol or other conditions. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Niacin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take niacin ?

Use niacin exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Niacin is sometimes taken at bedtime with a low-fat snack. Follow your doctor's instructions.

Niacin can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take niacin. These effects should disappear over time as you keep taking the medication.

Take niacin with a full glass of cold or cool water. Taking the medication with a hot drink may increase your risk of side effects such as flushing. Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Extended-release tablets and capsules contain higher strengths of the medicine than the regular tablets. Take only the dose that is correct for the type of niacin tablet or capsule you are using.

Niacin can cause you to have unusual results with certain medical tests (urine tests). Tell any doctor who treats you that you are using this medicine.

If you stop taking niacin for any length of time, talk with your doctor before starting the medication again. You may need to restart the medication at a lower dose.

While using niacin, you may need blood tests at your doctor's office. Your kidney or liver function may also need to be checked. Visit your doctor regularly.

Niacin is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Be sure to take the missed dose with food if you normally take your niacin dose with a meal or snack.

Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, dizziness, itching, vomiting, upset stomach, and flushing (warmth, redness, or tingly feeling).

What should I avoid?

Avoid drinking hot beverages shortly after taking niacin. Hot drinks can worsen the flushing effect (warmth, itching, redness, or tingly feeling under your skin).

Avoid drinking alcohol while taking niacin. Alcohol may increase your risk of liver damage, and can also worsen the flushing effects of this medicine.

Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take niacin. If you take either of these other medications, take them at least 4 to 6 hours before or after you take niacin.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Niacin side effects

Get emergency medical help if you have any of these signs of an allergic reaction to niacin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;

fast, pounding, or uneven heart beats;

feeling short of breath;

jaundice (yellowing of your skin or eyes); or

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

If you are diabetic, tell your doctor about any changes in your blood sugar levels.

Less serious side effects of niacin include:

warmth, redness, or tingly feeling under your skin;

itching, dry skin;

sweating or chills;

nausea, diarrhea, belching, gas;

muscle pain, leg cramps; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Niacin dosing information

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL):

Initial dose: 100 mg orally 3 times a day, with or after meals. Maintenance dose: 1 to 2 g orally 3 times a day, with or after meals. The maximum recommended dose is 6 g/day.

Extended Release (Niaspan): Initial dose: 500 mg orally once a day at bedtime after a low fat snack. Maximum recommended dose is 2 g/day.

Extended Release (Slo-Niacin): Initial dose: 250 to 750 mg orally once a day morning or evening.

Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):

Initial dose: 100 mg orally 3 times a day, with or after meals. Maintenance dose: 1 to 2 g orally 3 times a day, with or after meals. The maximum recommended dose is 6 g/day.

Extended Release (Niaspan): Initial dose: 500 mg orally once a day at bedtime after a low fat snack. Maximum recommended dose is 2 g/day.

Extended Release (Slo-Niacin): Initial dose: 250 to 750 mg orally once a day morning or evening.

Usual Adult Dose for Pellagra:

50 to 100 mg orally 3 to 4 times a day. The maximum recommended dose is 500 mg orally each day.

Usual Adult Dose for Niacin Deficiency:

10 to 20 mg orally once a day. Niacin may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products.

The maximum recommended dose is 100 mg orally each day.

Usual Pediatric Dose for Pellagra:

50 to 100 mg orally 3 times daily. Note: Some experts prefer niacinamide for treatment due to a more favorable side effect profile.

Usual Pediatric Dose for Niacin Deficiency:

Dosages are Recommended Daily Allowances (RDA): 1 to 5 months: 2 mg orally each day. 6 to 11 months: 3 mg orally each day. 1 to 3 years: 6 mg orally each day. 4 to 8 years: 8 mg orally each day. 9 to 13 years: 12 mg orally each day.

Males: 14 to 18 years: 16 mg orally each day.

Females: 14 to 18 years: 14 mg orally each day.

Niacin may also be administered parenterally as a component injectable multivitamin additives contained in parenteral nutrition products.

What other drugs will affect niacin?

Tell your doctor about all other cholesterol-lowering drugs you are taking with niacin, especially atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), or simvastatin (Zocor, Simcor, Vytorin, Juvisync).

Ask a doctor or pharmacist if it is safe for you to use niacin if you are also using any of the following drugs:

a blood thinner such as warfarin (Coumadin, Jantoven);

multivitamins or mineral supplements that contain niacin;

blood pressure or heart medications such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), nisoldipine (Sular), or verapamil (Calan, Covera, Isoptin, Verelan); or

heart medications such as doxazosin (Cardura), isosorbide (Dilatrate, Imdur, Isordil, Monoket, Sorbitrate), nitroglycerin (Nitro-Bid, Nitro-Dur, Nitrostat), prazosin (Minipress), or terazosin (Hytrin).

This list is not complete and other drugs may interact with niacin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More about niacin

Consumer resources

Professional resources

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about niacin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 8.04. Revision Date: 2012-05-15, 8:52:03 AM.

Drug Status

Fluconazole Oral Uses, Side Effects, Interactions, Pictures, Warnings - Dosing, Flukonazol

fluconazole

Uses

Fluconazole is used to prevent and treat a variety of fungal and yeast infections. It belongs to a class of drugs called azole antifungals. It works by stopping the growth of certain types of fungus.

How to use fluconazole

Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Dosage is based on your medical condition and response to treatment. For children, dosage is also based on weight. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor.

This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take it at the same time each day as directed.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow the fungus to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition persists or if it worsens.

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Get medical help right away if any of these rare but serious side effects occur: fast/irregular heartbeat. severe dizziness, fainting .

This drug may rarely cause serious liver disease. Get medical help right away if you develop any signs of liver disease, including: severe stomach /abdominal pain. persistent nausea/vomiting, yellowing eyes /skin. dark urine, unusual tiredness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking fluconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungal drugs (such as ketoconazole. itraconazole ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease .

Fluconazole may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using fluconazole, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure. slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating. diarrhea, or vomiting. Talk to your doctor about using fluconazole safely.

Although uncommon, this drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially rash. vomiting, diarrhea, and QT prolongation (see above).

During pregnancy. this medication should be used only when clearly needed. It may harm an unborn baby if taken in high doses daily during the first 3 months of pregnancy. For the treatment of vaginal yeast infections. medications applied in or around the vagina should be considered before this medication. Discuss the risks and benefits with your doctor.

Fluconazole passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast - feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Products that may interact with this drug include: clopidogrel.

Many drugs besides fluconazole may affect the heart rhythm (QT prolongation), including pimozide, quinidine, macrolide antibiotics (such as erythromycin), among others.

Fluconazole can slow down the removal of other medications from your body, which can affect how they work. An example of the affected drugs is cisapride, among others.

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: hallucinations, mental/mood changes.

Notes

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor directs you to do so. A different medication may be necessary in that case.

Laboratory and/or medical tests (such as liver function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store the tablets at room temperature away from light and moisture. Do not store in the bathroom.

Store the liquid suspension at room temperature or in the refrigerator. Do not freeze. Discard any unused medication after 14 days.

Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised May 2016. Copyright(c) 2016 First Databank, Inc.

Images

Izra D 40mg Cap Buy Medicines India S Best Online Pharmacy Network, Izra-D

Buy Medicines Online. Cash on Delivery in more than 3100+ pincodes across India.

You have to upload your prescription to buy medicines after you click on Add to Cart.

IZRA D 40MG CAP

Brief Info About Medicine

All Information published below is from public sources and cannot be used as expert's opinion. We request you to consult your doctor for more information

1 Why Is it Used ?

DOMPERIDONE :

Oral Nausea and vomiting Adult: 10-20 mg every 4-8 hr. Max: 80 mg/day. Child: >2 yr and >35 kg: 10-20 mg 3-4 times daily. Max: 80 mg daily. Oral Non-ulcer dyspepsia Adult: 10-20 mg tid and at night. Oral Migraine Adult: 20 mg every 4 hr, in combination with paracetamol, as required. Max: 4 doses in 24 hr. Rectal Nausea and vomiting Adult: 60 mg Max Dosage:bid. Child: 60 mg bid.

2 What are the Side Effects ?

DOMPERIDONE :

Drowsiness, extrapyramidal reactions, galactorrhoea, gynaecomastia; constipation or diarrhoea, lassitude, decreased libido, skin rash, itch. Potentially Fatal: Convulsions, arrhythmias and cardiac arrest, dysrrhythmias in patients with CV disease or hypokalaemia, patients on cancer chemotherapy. Seizures; hypertensive crisis in patients with phaeochromocytoma.

3 What Precautions should be taken ?

DOMPERIDONE :

10 CAP in Strip

Bicalutamida Medlineplus Medicinas, Bicalutamida

Bicalutamida

La bicalutamida se usa con otro medicamento (agonista de la hormona liberadora de gonadotropina [GnRH, por sus siglas en ingles], como leuprolida o goserelina) para tratar el cancer de prostata metastatico (cancer que empieza en la prostata y se propaga a otras partes del cuerpo). La bicalutamida pertenece a una clase de medicamentos llamados antiandrogenos no esteroides. Actua bloqueando el efecto del androgeno (una hormona masculina) para detener el crecimiento y la propagacion de las celulas del cancer.

?Como se debe usar este medicamento?

La bicalutamida viene en forma de tabletas que se toman por via oral. Por lo general se toma una vez al dia, por la manana o por la noche, con o sin alimentos. Tome la bicalutamida mas o menos a la misma hora todos los dias. Debe empezar a tomar la bicalutamida el mismo dia que le empiecen a inyectar la hormona liberadora de la hormona luteinizante. Siga cuidadosamente las instrucciones de la receta y pidales a su medico o farmaceutico que le expliquen cualquier cosa que no entienda. Tome la bicalutamida tal como se lo indiquen. No aumente ni disminuya la dosis, ni la tome con mas frecuencia que la indicada por su medico.

La bicalutamida junto con la hormona liberadora de la hormona luteinizante puede ayudar a detener la multiplicacion y propagacion de las celulas cancerosas, pero no cura el cancer de prostata. Siga tomando la bicalutamida y la hormona mencionada aunque se sienta mejor. No deje de tomar estos medicamentos sin consultar a su medico.

?Que otro uso se le da a este medicamento?

A veces se receta este medicamento para otros usos; pidale mas informacion a su medico o a su farmaceutico.

?Cuales son las precauciones especiales que debo seguir?

Antes de tomar bicalutamida,

digales a su medico y a su farmaceutico si es alergico a la bicalutamida, a cualquier otro medicamento o a alguno de los ingredientes de las tabletas de bicalutamida. Pidale a su farmaceutico una lista de los ingredientes.

digales a su medico y a su farmaceutico que otros medicamentos con y sin receta, vitaminas, suplementos nutricionales y productos herbales esta tomando o piensa tomar. No olvide mencionar ninguno de los siguientes: alprazolam (Xanax); anticoagulantes ('diluyentes de la sangre') como warfarina (Coumadin); aripiprazol (Abilify); buspirona (Buspar); bloqueadores del canal de calcio como amlodipina (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipina (Plendil), nifedipina (Adalat, Procardia), nisoldipina (Sular) y verapamilo (Calan, Covera, Isoptin, Verelan); clorfeniramina; medicamentos para reducir el colesterol (estatinas), como atorvastatina (Lipitor), lovastatina (Mevacor) y simvastatina (Zocor); claritromicina (Biaxin); ciclosporina (Neoral, Sandimmune); diazepam (Valium); eritromicina (E. E.S. E-Mycin, Erythrocin); inhibidores de la proteasa del VIH, como indinavir (Crixivan), ritonavir (Norvir) y saquinavir (Invirase, Fortovase); metadona (Dolophine); midazolam (Versed); pimozida (Orap); quinidina (Quinidex, Quinaglute); quinina; sildenafilo (Viagra); tacrolimus (Prograf); tamoxifeno (Nolvadex); telitromicina (Ketek); trazodona (Desyrel); triazolam (Halcion); y vincristina (Vincasar). Muchos otros medicamentos tambien pueden interactuar con la bicalutamida, asi que no olvide decirle a su medico todos los medicamentos que este tomando, inclusive los que no aparecen en esta lista.

informele a su medico si tiene o alguna vez ha tenido una enfermedad del higado.

tenga presente que la bicalutamida es exclusivamente para uso masculino. Si las mujeres embarazadas toman bicalutamida, esta puede causar anormalidades en el feto (el bebe en el vientre). Ninguna mujer embarazada o que pudiera quedar embarazada debe tomar bicalutamida. Si toma bicalutamida estando embarazada, llame a su medico de inmediato.

?Que dieta especial debo seguir mientras tomo este medicamento?

A menos que su medico le indique lo contrario, continue con su dieta normal.

?Que tengo que hacer si me olvido de tomar una dosis?

Si olvida tomar una dosis, tomela en cuanto se acuerde. No obstante, si ya casi es hora de la dosis siguiente, salte la que olvido y continue con su horario de medicacion normal. No tome una dosis doble para compensar la que olvido.

?Cuales son los efectos secundarios que podria provocar este medicamento?

La bicalutamida puede provocar efectos secundarios. Avisele a su medico si cualquiera de estos sintomas es grave o no desaparece:

bochornos o ruborizacion

dolor de huesos, espalda o pelvis

debilidad muscular

dolor en los musculos o las articulaciones

dolor de cabeza

falta de aire

aumento de la presion arterial

hinchazon) de manos, pies, tobillos o pantorrillas

tos

estrenimiento

nauseas

vomitos

dolor abdominal

diarrea

gases

alteraciones del peso corporal (perdida o aumento)

perdida de apetito

mareos

dolor, ardor o sensacion de hormigueo en las manos o los pies

dificultad para dormirse

sensacion de intranquilidad o temor

sarpullido

sudoracion

incapacidad para lograr o mantener la ereccion

necesidad de orinar con frecuencia por la noche

sangre en la orina

dificultad para orinar o dolor al orinar

necesidad urgente y frecuente de orinar

dificultad para vaciar la vejiga urinaria

dolor o inflamacion de los senos

Algunos efectos secundarios pueden ser graves. Si presenta alguno de estos sintomas, llame a su medico de inmediato:

coloracion amarilla de la piel o los ojos

dolor en la parte superior derecha del abdomen

cansancio excesivo

sangrado o moretones fuera de lo comun

falta de energia

malestar estomacal

perdida de apetito

sintomas parecidos a los de la influenza

dolor sordo o punzante en el costado

dolor en el pecho

La bicalutamida puede provocar otros efectos secundarios. Llame a su medico si tiene algun problema inesperado mientras toma este medicamento.

Si desarrolla un efecto secundario grave, usted o su doctor puede enviar un informe al programa de divulgacion de efectos adversos 'MedWatch' de la Administracion de Alimentos y Medicamentos (FDA, por su sigla en ingles) en la pagina de Internet (http://www. fda. gov/Safety/MedWatch ) o por telefono al 1-800-332-1088.

?Como debo almacenar o desechar este medicamento?

Mantenga este producto en su envase original, perfectamente cerrado y fuera del alcance de los ninos. Guardelo a temperatura ambiente y en un lugar alejado del exceso de calor y humedad (nunca en el cuarto de bano). Deseche todos los medicamentos que esten vencidos o que ya no necesite. Preguntele a su farmaceutico cual es la manera adecuada de desechar los medicamentos.

?Que debo hacer en caso de una sobredosis?

En caso de una sobredosis, llame a la oficina local de control de envenenamiento al 1-800-222-1222. Si la victima esta inconsciente, o no respira, llame inmediatamente al 911.

Strill - Wookieepedia, Stril

Strill

Members

" What's a strill? " " A disgustingly ugly, smelly Mandalorian hunting animal. You can't mistake it for any other species, not even in this menagerie of a city. " ―Perrive and Kal Skirata [src]

Strills were a species of highly intelligent. carnivorous mammals native to the planet of Mandalore in the Outer Rim. The one-meter - long, six-legged creatures, with their loose folds of leathery skin, were generally considered physically unattractive by many beings, and their uniquely pungent odor was off-putting to most male humanoids. However, a number of Mandalorians took to keeping strills—or striile in Mando'a — as pets, making use of their naturally ferocious predatory instincts as hunting animals, and the long-lived creatures often became life-long companions of their Mandalorian masters. One such strill by the name of Lord Mirdalan was the constant partner of the Mandalorian soldier Walon Vau. and the two were nearly inseparable until the time of Vau's death. whereupon the affectionately nicknamed "Mird" was entrusted to close friend Jaing Skirata for care. Both doted upon the creature, and in return, enjoyed fierce loyalty from the strill. Strills also behaved in a maternal fashion in the presence of a pregnant female or infant. a trait owed to their hermaphroditic characteristics, and one which manifested in an innate protectiveness toward the female or youngling, and an instinct to construct a nest.

Contents

Biology and appearance Edit

" Can Mird have pups? " " Mird can bear pups and sire them. But don't ask me how hermaphroditic reproduction works in practice. All I know is that if Mird meets the strill of its dreams, then they end up with a litter of little strills. " ―Nyreen Vollen and Walon Vau. discussing the strill, Lord Mirdalan [src]

Strills were a species of predatory animals indigenous to the Outer Rim world of Mandalore. [3] measuring close to a meter in length, on average. Hermaphroditic mammals. [2] strills were equally capable of both siring and bearing offspring with a second strill; young strills were commonly referred to as pups. [3] Covered in thick fur of a gold [7] or gray-tan color. [5] strills possessed numerous folds of loose, leathery skin that stretched all the way to its thin, whip - like tail, and could be used to form wing membranes between their six strong legs that allowed the creatures to glide from high places and even fly short distances by flapping their legs in unison. Furthermore, strills were capable of carrying substantial loads while flying, including the weight of a full-grown Human male. [7] Strills could live up to three or four times the span of a natural human's lifetime, and it was common for Mandalorian owners to entrust their beloved pets to their clan kinsmen following their deaths. Strills had gold-colored eyes and gray tongues. [1] and their wide mouths were filled with sharp fangs. perfect for a carnivorous diet and powerful enough to bite through skull bone. but were also known for the abundant amount of saliva which they excreted. [3] Strills could withstand significantly cold temperatures for extended periods of time, and their hearing was far more acute than a Human's. [1] Aside from these features, one of the most identifiable traits of a strill was the strong, acrid stench they gave off. To male Humans, the smell was often considered repulsive, but an individual could become acclimated to the scent with continued exposure. Human females and non-humanoid species, though, did not find the strill's scent displeasing, contributing to its continued effectiveness as a hunter. [3] Unfortunately, strills were susceptible to brain tumors which could, as a result, drive the animals to irrational acts of anger and aggression, even to the point of attacking their owner. [8]

Behavior and intelligence Edit

" Is a strill safe around a small child? " " Being hermaphroditic, all strills have a maternal streak, Ordo. Hence the endless nest building when it sees the baby. " ―Ordo Skirata and Walon Vau [src]

Lord Mirdalan, a strill owned by Walon Vau

Strills were highly intelligent creatures, capable of understanding verbal commands and intuiting the feelings of those sentients around it. [7] Strills made a variety of noises, including baying while hunting, whines and moans when under stress, and squeaks and low grumbles when pleased. [1] They were territorial creatures, marking the area they claimed as their own by rubbing their saliva-covered jowls and spraying from their strong scent glands around the perimeter. Domesticated strills did not often leave their owners, but occasionally did roam within the boundaries of their territory independently. [4] Their hermaphroditic nature gave strills a strong maternal instinct, and they could often sense when a nearby female was pregnant. [2] Despite their predatory ferocity, strills were extremely protective of their young and the offspring of those within its social sphere. Human infants needed not to fear a nearby strill and, in fact, strills were known to construct nests for human children much as they would for their own pups. [4]

Strills were skilled trackers and fierce hunters, capable of taking down large prey such as shatuals and carrying the carcass back to their abode. [1] Their sharp claws allowed the strill to climb the sides of buildings [7] and trees. where they would wait to ambush a prospective target. Once the prey was in range, the strill leaped from their high perch and, using their leathery wings formed from their loose folds of skin, glided through the air, swooping down for the kill. [2] Strills were known to enjoy milk. and preferred to eat their own kill after a hunt, [7] though they were not opposed to sharing the spoils with its owner and associates, and also hunted to acquire food for its young or any offspring it felt protective toward. When domesticated, strills were extremely loyal and protective of their masters and their surrounding families. [1]

History Edit

" I promised Mird's last owner I'd look after it when he passed to the manda . Strills live a lot longer than we do. " " Heard of them, but never seen one. " " They're nearly extinct on Mandalore. Mird—well, you might say it's a black ops strill. Saw a lot of commando action in a few wars. " ―Jaing Skirata and Mirta Gev [src]

Strills were an indigenous species of the planet Mandalore, that had adapted to hunting in the Outer Rim world's [1] veshok forests. [4] During the course of Mandalore's long history, the Mandalorians took to capturing strills, domesticating them, and keeping the creatures as pets. [2] Their intelligence, hunting skills, and incredible loyalty were praised by their Mandalorian masters, and it was not uncommon for the long-lived animals to be passed down through a clan's generations. [1] In the Mandalorian language. Mando'a . the word for strill was striil . [9]

One strill by the name of Lord Mirdalan — often known by the affectionate nickname of Mird—was the friend and pet of the Mandalorian soldier. Walon Vau. Mird had been with Vau for the majority of his life leading up to the final years of the Galactic Republic. and was his near constant companion. The strill followed Vau to the aquatic world of Kamino when he was chosen to be a member of the Cuy'val Dar . a group of training sergeants tasked with training the Grand Army of the Republic's special forces clone commandos. and on Kamino Mird developed an enjoyment for stalking Kaminoans within Tipoca City. even killing one of the blue - eyed lower caste. [1] When the Clone Wars broke out between the Republic and the Confederacy of Independent Systems. Mird joined Vau and a number of clone commandos in helping to bring down a Jabiimi terrorist cell responsible for a number of bombing attacks on Coruscant. After Vau shot and killed the terrorist leader. Mird was responsible for recovering the body and the criminal files held with it. [7] In the second year of the Clone Wars, Vau raided the Dressian Kiolsh Merchant Bank on Mygeeto. in order to steal the inheritance his estranged mother and father had denied him. During the course of his escape, Vau fell through the Mygeetan ice; Mird refused to abandon its master and attempted to keep Vau warm with its own body until rescue arrived in the form of fellow Cuy'val Dar member Kal Skirata. Skirata's adopted daughter, Etain Tur-Mukan. had her son Venku later that year, and Mird subsequently became very protective of the child. He also built nests for the baby on a number of occasions, collecting sheets and clothing in order to do so. [1] The strill later became a resident of Skirata's clan home on Mandalore, Kyrimorut. marking the land around the farm and homestead as its own, [4] and preferred to spend its time hunting or simply laying about, basking in the attention of its master or the other residents of Kyrimorut. [3]

As of the year 40 ABY. strills had become a rare sight on Mandalore, to the point which they were thought to be nearly extinct. By that time, Lord Mirdalan had entered into the possession of Kal Skirata's adopted son, Jaing Skirata. as his former master, Vau, was deceased. Mird continued to act as Skirata's partner in his exploits as a bounty hunter. [10] and in 41 ABY. the two attended a feast in honor of the wedding of Ghes Orade and Mirta Gev held in Mandalore's capital city. Keldabe. The Oyu'baat hotel and tapcaf in Keldabe displayed a sign over the front door in which the words "No Strills Inside" was inscribed in both Mando'a and Basic. However, bar patron Baltan Carid jovially suggested on one occasion that a strill was, in fact, the resident of the Oyu'baat ' s executive suite. Another strill had been kept by a friend of the former Jedi - turned-Mandalorian by the name of Gotab. until the creature became crazed as a result of a malignant brain tumor and had to be put down in order to end its suffering. [8]

Behind the scenes Edit

The strill was first mentioned in the 2004 novel. Republic Commando: Hard Contact . by author Karen Traviss. The vague reference to an animal adept at hunting and tracking would be fully realized in the novel's sequel, Republic Commando: Triple Zero . where the first strill, Lord Mirdalan, was introduced to Star Wars canon. Lord Mirdalan went on to become a recurring character in Traviss' Republic and Imperial Commando series. featuring in the subsequent True Colors . Order 66 . and Imperial Commando: 501st novels. To date, Lord Mirdalan has been the most prominently featured strill in the Star Wars universe.

Appearances Edit

Sources Edit

Notes and references Edit

Arizona Radiation Regulatory Agency, Azona

Disclosure Statement

Disclosure Statement of locations where all notices of the meetings of the Arizona Radiation Regulatory Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners will be posted. Pursuant to A. R.S. §38-431.02(A)(1)(a), the Arizona Radiation Regulatory Agency Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners hereby states that all notices of the meetings of the Arizona Radiation Regulatory Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners and any of their committees and subcommittees will be posted at the office of the Arizona Radiation Regulatory Agency/Arizona Medical Radiologic Technology Board of Examiners at 4814 South 40th Street Phoenix, Arizona 85040. This location is open to the public Monday through Friday from 8 a. m. to 5 p. m. except for legal holidays.

The above notices for all meetings will also be posted on the website calendar. Notices will indicate the date, time, and place of the meeting and will include an agenda or information concerning the manner in which the public may obtain an agenda for the meeting.

Meeting minutes are available at the Agency, 4814 South 40th Street Phoenix, AZ 85040

NIR Slideshow

New and current laser hair removal registrants or facilities application resources can be found in Medical Laser Facilities

The ultraviolet (UV) region of the electromagnetic spectrum is intermediate in wavelength and frequency between the x-ray and the visible regions.

The ultraviolet (UV) region of the electromagnetic spectrum is intermediate in wavelength and frequency between the x-ray and the visible regions.

Arizona Radiation Regulatory Agency (ARRA)

The Arizona Radiation Regulatory Agency (ARRA), known as the Arizona Atomic Energy Commission until 1980, originated in 1964. Brian Goretzki is ARRA's Interim Director. ARRA is responsible for the conduct of a statewide radiological health and safety program and for the enforcement of State rules and regulations for the control of ionizing and non-ionizing radiation. ARRA is comprised of six program areas.

RAM - Radioactive Materials is responsible for licensing and inspecting medical, industrial and academic users of radioactive materials.

XRAY - XRay Compliance registers and inspects x-ray producing machines throughout the State.

NIR - Non-Ionizing Radiation Compliance registers and inspects non-ionizing devices, such as class 3b and class 4 lasers, tanning beds, radiofrequency devices, commercial microwave ovens, and High Intensity Mercury Vapor Discharge Lamps throughout the State. NIR is also responsible for licensing laser technicians for cosmetic procedures to ensure all safety and training requirements have been met.

RML - The Radiation Measurements Laboratory maintains surveillance over radiation levels in the vicinity of the Palo Verde Nuclear Generating Station as well as other areas within the State. RML activities also include public information and technical guidance in assessing radon in Arizona.

ER - Emergency Response involves the preparation for and response to radiation accidents statewide and includes the offsite technical response to any incident that occurs at the PVNGS. The ER program also provides training for police, fire and medical personnel.

MRTBE - The Medical Radiologic Technology Board of Examiners licenses and investigates professionals to practice various specialties of medical imaging and therapy using ionizing radiation. The Board also accepts complaints against licensees, investigates allegations and administratively adjudicates complaints. The Board currently licenses over 8,000 technologists.

Disclosure Statement

Disclosure Statement of locations where all notices of the meetings of the Arizona Radiation Regulatory Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners will be posted. Pursuant to A. R.S. §38-431.02(A)(1)(a), the Arizona Radiation Regulatory Agency Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners hereby states that all notices of the meetings of the Arizona Radiation Regulatory Hearing Board and the Arizona Medical Radiologic Technology Board of Examiners and any of their committees and subcommittees will be posted at the office of the Arizona Radiation Regulatory Agency/Arizona Medical Radiologic Technology Board of Examiners at 4814 South 40th Street Phoenix, Arizona 85040. This location is open to the public Monday through Friday from 8 a. m. to 5 p. m. except for legal holidays.

The above notices for all meetings will also be posted on the website calendar. Notices will indicate the date, time, and place of the meeting and will include an agenda or information concerning the manner in which the public may obtain an agenda for the meeting.

Meeting minutes are available at the Agency, 4814 South 40th Street Phoenix, AZ 85040

Opelead, Opelead

Why register with MediGuard?

We are a free monitoring service designed for patients like you who want to be in the driver seat of your medical treatment. We have a community of more than 2.6 million members and offer the services below.

Medication Information Personalized Risk Rating Easy to understand overview Serious Side Effects Printable Medication List

Information you can understand Overview on Safety Alerts & Recalls Overview of Medications & Conditions

Community of patients Members’ Feedback Members Treatment Satisfaction

Health condition information Easy to understand overview Commonly Used Medications

Safety checks Safety Alerts & Recalls Drug - Drug Interaction Drug - Condition Interaction

Research participation Option to participate in medical surveys & studies*

Opelead

What is your Risk Rating for this medicine?

The risk of serious side effects for taking this medicine can be different if you take other medicines or if you suffer from a condition. Get your Risk Rating by creating a profile in a few steps.

Benefits:

We monitor your health and alert you to any safety updates and recalls.

You get to talk directly to other members about their experience.

You can create profiles for you and your loved ones.

Create my Profile Learn more about Risk Ratings

Other Names

Expand to see all

Share your story! Tell us how MediGuard has helped you or someone you love. Download the MediGuard Mobile App to manage your prescription and over-the-counter medications, for free. Taking multiple medications puts you at risk for possible drug-drug interactions Monitor the medical treatment of you and your loved ones.

DISCLAIMER: MediGuard is not intended to be a substitute for professional medical advice. MediGuard cannot and does not take into consideration every possible interaction or account for individual responses to medicine. Different individuals may respond to medication in different ways. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective, or appropriate for any given patient. Always seek the advice of a qualified health provider with any questions you may have before making any changes to your treatment. The use of the MediGuard site and its content is at your own risk. The MediGuard site and the information contained in it is intended for users in the United States and information in other countries may be different.

© Quintiles 2016

Trental (Pentoxifylline) Drug Information Side Effects And Drug Interactions - Prescribing Informati

DRUG INTERACTIONS

Drug-Drug Interactions

Antacids : In patients with digestive side effects, antacids may be administered with Trental. In comparative bioavailability study, no interference with absorption of Trental by antacids was observed.

Antihypertensive agents : Trental (pentoxifylline) may potentiate the action of antihypertensive agents. Patients receiving these agents require blood pressure monitoring and possibly a dose reduction of the antihypertensive agents.

Anticoagulants : There have been reports of bleeding and/or prolonged prothrombin time in patients treated with Trental with and without anticoagulants, including vitamin K antagonists, or platelet aggregation inhibitors. Monitoring of anti-coagulant activity in these patients is recommended when pentoxifylline is introduced or the dose is changed.

Patients on warfarin should have more frequent monitoring of prothrombin time, while patients with other risk factors complicated by hemorrhage (e. g. recent surgery) should have periodic examinations for signs of bleeding, including hematocrit and haemoglobin.

Cimetidine : During concurrent use of cimetidine and pentoxifylline, cimetidine has been shown to significantly increase the steady-state plasma concentration of pentoxifylline, which may enhance the possibility of adverse effects.

Erythromycin : No data are available on the possible interaction of Trental and erythromycin. However concurrent administration of erythromycin and theomycin has resulted in significant elevation of serum theophylline levels with toxic reactions.

Hypoglycemic agents : The blood-sugar lowering effect of insulin or oral antidiabetic agents may be potentiated. In patients treated with hypoglycemic agents, a moderate adjustment in the dose of these agents may be required when Trental is prescribed. Therefore it is recommended that patients under medication for diabetes mellitus be carefully monitored

Sympathomimetics : Combined use with other xanthines or with sympathomimetics may cause excessive CNS stimulation.

Theophylline : Although causality has not been established, concurrent use of pentoxifylline with theophylline has resulted in elevated theophylline plasma levels, which may enhance the possibility of adverse effects.

Drug-Food Interactions

Interactions with food have not been established.

Drug-Herb Interactions

Interactions with herbal product have not been established.

Drug-Laboratory Interactions

Interactions with laboratory tests have not been established.

Drug-Lifestyle Interactions

Interactions with lifestyles have not been established.

Read the Trental Drug Interactions Center for a complete guide to possible interactions

This monograph has been modified to include the generic and brand name in many instances.

Crohnax, Crohnax

Visit our booth at COSME TOKYO 2016! January 20-22, 2016 at Tokyo Big Sight

Farmina will be exhibiting at the COSME TOKYO 2016 trade show, Japan’s leading cosmetics development exhibition gathering 700 exhibitors.

Following Expo East in Baltimore, it’s time to return to Europe, this time with a focus on the Nordic markets.

FARMINA SP. Z O. O. • UL. LIPSKA 44 • 30-721 KRAKÓW T +48 12 290 90 00 • F +48 12 290 90 50 • E info@farmina. pl

© Farmina and other authors. All rights reserved. Copying the content without consent of the copy right holder is forbidden.

Kopen Dresplan (Oxytrol) Zonder Recept, Dresplan

Dresplan (Oxytrol) Kopen Online Zonder Recept

Dresplan (Oxytrol) Toelichting

Dresplan medicatie bestaat uit oxybutynine dat spierspasmen van de blaas als urine afneemt: systeem.

Dresplan functies door vermindering spierspasmen van de blaas en urine: systeem.

General titel geassocieerd met Dresplan is eigenlijk Oxybutynine.

Merk geassocieerd met Dresplan is eigenlijk Dresplan.

Dresplan (Oxytrol) Dosis

Dresplan komt in:

tweede. 5mg lagere dosis frictiemateriaal

5mg normale dosis frictiemateriaal

Om gebruik te maken van de werkelijke Dresplan plot te maken, geopend van de werkelijke overdekte zak evenals weg te nemen de beschermende voering.

Gebruik de werkelijke Dresplan complot om een ??aantal grondig te reinigen, uitgedroogd gebied op de buik, stijlvol of zelfs bil. Voorkomen dat de porien en de huid die is vettig, geirriteerd of zelfs geschaad. Voorkomen dat het zetten van uw perceel aan de porien en de huid regio die zullen worden toegepast met een taille of zelfs strakke kleding.

Duw de werkelijke Dresplan plot op uw huid en druk deze recht naar beneden sterk samen met uw vingertoppen. Zorg ervoor dat de eigenlijke plot is eigenlijk mooi gedekt rond de zijkanten. Wanneer correct gebruikt, de eigenlijke plot moet op terwijl gaan zwemmen of zelfs het wassen te blijven.

Houd de eigenlijke plot in positie en zet het op met betrekking tot de drie of vier keer. Je moet het perceel beinvloeden twee keer per week. Elke keer als je een nieuwe plot te gebruiken, selecteert u een verschillende porien en de huid regio op de buik, stijlvol of zelfs bil. Meestal niet de plot naar het exact dezelfde porien en de huid twee keer binnen 1 week gebruiken.

Poging om uw Dresplan plot te verbeteren op een enkel 2 dagen per week (bijvoorbeeld omdat elke Weekend en donderdag). Er bestaat een werkschema bedrukt binnen de bundel van de geneeskunde om u te helpen het genereren van een constante-patch veranderen routine.

Als de plot valt weg, proberen vast te houden dit weer terug op. Indien deze niet op zal blijven kopen een nieuwe tandenborstel met een nieuwe 1 en zet het op tot de volgende normale patch wisseltijd. Meestal niet het verbeteren van uw routine, ook al heb je een gloednieuwe perceel te gebruiken om een ??die aanbiedingen gedaald weg te veranderen.

Vlak na het elimineren van de plot, storten deze in twee dus het blijft bij elkaar en gooien dit terzijde binnen een locatie waar kinderen of zelfs huisdieren zijn niet in staat om dit te bereiken.

Dresplan (Oxytrol) ontbreekt in verband met de dosering

Meestal krijgt niet de dubbele dosering. In het geval u de dosering die u nodig hebt om het te dragen als je eenmaal in het achterhoofd te houden met betrekking tot uw ontbreekt overslaan. Wanneer het tijd is voor de dosering die u nodig hebt om te dragen op je eigen normale dosering routine.

Dresplan (Oxytrol) Overdose

In het geval u Dresplan overdosis en je ook voorkomen dat geweldig je nodig hebt om direct te controleren uw arts of zelfs arts. Geassocieerd met Dresplan overdosering: uneasyness, tintelend gevoel, temperatuur, ongelijke hartslag, overgeven, plassen onder normale niet echt dan ook.

Dresplan (Oxytrol) Opslagruimte

Shop in de ruimte een temperatuur tussen 10 en 30 niveaus D (59 en zesentachtig niveaus F) tegen vocht, vocht en temperatuur Versterk elke vorm van ongerepte medicatie na het verstrijken dag. Handhaven van het bereiken van kinderen.

Dresplan (Oxytrol) Negatieve effecten

Dresplan biedt de negatieve effecten. De meest typische neiging om:

matige porien en de huid jeuk, branderig gevoel op, ontsteking of zelfs vlekken waarin een perceel werd gebruikt frictiemateriaal

vermoeidheid frictiemateriaal

slaperigheid frictiemateriaal

enige zwakte frictiemateriaal

wazig gezichtsvermogen frictiemateriaal

uitgedroogde mond gebied frictiemateriaal

innemendheid, tingley of zelfs ontsteking onder de huid wrijving materiaal

misselijkheid of braken frictiemateriaal

het gooien van frictiemateriaal

buik ongemak frictiemateriaal

congestie of zelfs diarree frictiemateriaal

uitgedroogd oog frictiemateriaal

verstopte neus-gebied frictiemateriaal

lage rugpijn frictiemateriaal

sensatie benadrukte frictiemateriaal

slapeloosheid frictiemateriaal

Veel minder typische en ernstige nadelige gevolgen voor de hele behulp Dresplan:

allergische reactie reacties (urticaria, en uitademen problemen, allergie, evenals eruptie) frictiemateriaal

temperatuur, samen met een zeer hete, uitgedroogde huid frictiemateriaal

ongelijke hartslag frictiemateriaal

ongemak, verbranden of zelfs een aantal andere problemen wanneer het plassen frictiemateriaal

ernstige jeuk, verbranden of zelfs schroeien dat zal niet schoon van binnen vele uren direct na het elimineren van je huid plot frictiemateriaal

Negatieve effecten zijn er aanwijzingen afhankelijk zijn van medicijnen die u zou kunnen gebruiken, maar bovendien rekenen op uw welzijn conditie en andere aspecten.

Dresplan (Oxytrol) Contra-indicaties

Meestal niet Dresplan te krijgen in het geval u gevoelig om elementen Dresplan zijn.

Wees voorzichtig, samen met Dresplan wanneer u verwacht en hebben nurseling.

Meestal krijgt niet Dresplan voor degenen die zonder behandeling of zelfs uit de hand glaucoom.

Meestal krijgt niet Dresplan voor degenen die de congestie in je spijsverteringsstelsel (maag of zelfs darmen).

Meestal krijgt niet Dresplan voor degenen die plassen en / of niet naar de wc kunnen hebben verminderd.

Wees voorzichtig met Dresplan als u glaucoom, ziekten in de lever, nier ziekte, myasthenia gravis, grotere prostaat, darmkanaal probleem, zoals ulceratieve colitis, buik probleem bijvoorbeeld gastro poisson ziekte (GERD) bezitten of nog langzamer spijsvertering.

Wees voorzichtig, samen met Dresplan als je atropine (Donnatal, evenals anderen), belladonna ;, clidinium (Quarzan), dicyclomine (Bentyl), glycopyrrolaat (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin en anderen), mepenzolate (Cantil), methantheline (Provocholine), methscopolamine (Pamine), propantheline (Pro-Banthine), scopolamine (Transderm-Scop), claritromycine (Biaxin), erythromycine (E-mycin, Electronic. Electronic. H. Ery-Tab, Erythrocin), itraconazol (Trisporal) of zelfs ketoconazol (Nizoral).

Vermijd zware reinigingsmiddelen, alcoholische dranken, teennagel glans eliminator of zelfs sommige andere oplosmiddelen die de huid zou kunnen verergeren.

Voorkom te warm of zelfs uitgedroogd hele lichaamsbeweging en warm weer.

voorkomen dat apparaat reizen.

Het kan schadelijk zijn voor Dresplan behulp ineens voorkomen.

Dresplan (Oxytrol) Veelgestelde vragen

Queen: Wat is Dresplan precies?

De: Dresplan medicatie bestaat uit oxybutynine dat spierspasmen afneemt van de blaas als urine: system. A

Queen: Wat er precies is Dresplan gebruikt voor?

De: Dresplan wordt gebruikt om te gaan met geassocieerd met een overactieve blaas: regelmatige of zelfs belangrijker plassen, incontinentie (urineverlies), verbeterde nacht peeing. A

Queen: Dus hoe precies doet Dresplan functie?

De: Dresplan functies door het verminderen van spierspasmen van de blaas als urine: system. A

Queen: Zeer beste algemene titel in verband met Dresplan?

De: General titel is eigenlijk Oxybutynin. A

Queen: Precies wat moet ik fag situatie als gevolg van de dosering ontbreekt?

De: In geval mis je de plot op het geplande tijdstip te wijzigen, vervang dan de eigenlijke plot als je eenmaal in het achterhoofd te houden. Doe de werkelijke plot tot de volgende normale-patch veranderende tijd. Meestal niet het verbeteren van uw routine, ook al zet je op het gloednieuwe plot voor minder dan drie keer. Meestal niet tegelijkertijd gebruiken 2 gebieden te creeren in de overgeslagen dosage. A

Queen: Weet jij de geassocieerd met Dresplan overdosering?

De: Haalbaar geassocieerd met overdosering: uneasyness, tintelend gevoel, temperatuur, ongelijke hartslag, overgeven, plassen onder normale niet echt whatsoever. A

Kopen Dresplan (Oxytrol) online, kopen Dresplan (Oxytrol) online zonder voorschrift, kopen Dresplan (Oxytrol) zonder recept, kopen Dresplan (Oxytrol) goedkoop, kopen Dresplan (Oxytrol) zonder voorschrift, kopen Dresplan (Oxytrol) uit Canada, kopen Dresplan (Oxytrol) Canada, inkopen Dresplan (Oxytrol) online, inkopen Dresplan (Oxytrol) online no prescription, bestelling Dresplan (Oxytrol) zonder recept, Dresplan (Oxytrol) orale pil

Zoeken

Mensen Ook Zoeken

Omnivisor System - Telehealth Technology Systems, Omipro

OMNIVISOR

CARDIOCOM’S OMNIVISOR SYSTEM CONNECTS YOU WITH YOUR PATIENTS MORE EFFICIENTLY THAN ANY OTHER TELEHEALTH SYSTEM

Cardiocom’s OMNIVISOR Management System connects you with your patients more efficiently than any other telehealth management system. OMNIVISOR features “management by exception”, clinical telehealth algorithms and guided workflow processes that standardize care and provide highly efficient, remote patient management of large patient populations. Most importantly OMNIVISOR facilitates targeted intervention that results in reduced acute care hospitalizations and improved quality of life.

FEATURES OF OMNIVISOR INCLUDE:

TARGET, TIMELY INTERVENTION

OMNIVISOR’S clinical management software is a telehealth workflow management tool. The System prioritizes and categorizes daily interventions and guides your care team through an efficient intervention process. OMNIVISOR was developed by Cardiocom using evidence-based medicine and clinical practice guidelines. OMNIVISOR incorporates proven, rules driven telehealth algorithms that can be customized for your population and are configurable at an individual patient level. OMNIVISOR facilitates high care management ratios allowing one nurse to remotely manage several hundred patients.

DETAILED OBJECTIVE PATIENT AND POPULATION REPORTS

To maximize ease-of-use for the healthcare provider, daily biometric data is trended over time and displayed graphically for easy viewing. The program integrates health status and care plan compliance questions into the clinical profile for each patient. Users are also given the option to define parameters and configure data to meet specific needs. All information can be exported in PDF, Excel or other report formats.

OMNIVISOR seamlessly integrates with other point-of-care and electronic medical record enterprise software applications. The distinct separation of major software components within the OMNIVISOR application also allows for flexible implementation to meet the unique needs of your technical environment. Cardiocom has seamless two-way interfaces with many of the world’s leading enterprise healthcare software companies. Integration methods include: HL7, web-services, inline frame (iframe) and other custom data exchanges.

ENTERPRISE TELEHEALTH SYSTEM

OMNIVISOR is an enterprise level telehealth management system that features a web-based ASP. net framework, N-Tier architecture, SQL relational database and Secure Socket Layer connection. The System provides configurable roles, views and data elements to meet your unique operating needs. The System includes: demographics, contacts, labs, observations, medications, notes, configurable health querying and education, monitoring parameters and integrated security.

SYSTEM HOSTING FLEXIBILITY

Cardiocom provides clients with flexible hosting options for telehealth data access. Cardiocom’s web hosted program offers rapid deployment and maintenance-free operation with client data access via a secure web browser. Alternatively, the OMNIVISOR server can be located within a client’s internal data center. In either system configuration, (Cardiocom or client hosted), the OMNIVISOR application is accessed via a standard web browser, which means that individual client software installation is not necessary.

[ 1 2 3 4 5 6 7 8 9 10 15 ]