About Ormet Circuits, Inc, Oramet

About Ormet Circuits, Inc.

Ormet Circuits, Incorporated (Ormet) is a privately held company, engaged in the design, manufacture, and sale of electrically conductive sintering pastes for use in the assembly of advanced electronic devices. Located in San Diego, California, the Company has distribution and representative organizations throughout the world.

Ormet sintering pastes are lead-free and demonstrate high electrical and thermal conductivity. When heated, they undergo a transformation called Transient Liquid Phase Sintering (TLPS), forming a strong metallic bond with solderable surfaces. Once this process is completed, the sintered paste will not reflow, thereby increasing the reliability of these devices. Ormet pastes have been thoroughly qualified through exhaustive testing at major companies. The company maintains a growing body of intellectual property including 24 patents covering both the composition of their products and the use of their products in electronics applications.

Ormet sintering pastes are being used in semiconductor packaging, printed circuit boards, and as a Lead-free alternative to existing interconnect technologies in electronic assemblies As the need for more complex electronic circuit boards and semiconductor packages continues to grow, new methods of forming environmentally friendly interconnections are becoming a necessity. The company`s achievements over the past several years are enabling it to benefit from these emerging market opportunities. With an experienced management and technical team, Ormet is addressing an ever increasing array of applications.

PCB Interconnect Materials

High Density Interconnects (HDI) in Printed Circuit Boards have traditionally been made using electroplating. However, advanced requirements in ball grid array density, high PCB layer counts, and fine diameter vias have created the need for paste solutions. Because the PCB layers connected by paste may be tested individually, as opposed to the sequential electroplating process which can only be tested in its final form, overall yields are significantly improved. Also, the Ormet process requires a substantially lower capital investment and is much more environmentally friendly than conventional plating lines.

Power Die Attach

The electronics industry is pushing forward to reduce the use of hazardous materials in the manufacture of components and assemblies. Ormet is working with the leaders in the power semiconductor industry to commercialize the next generation lead-free die attachment material for power semiconductor devices. Ormet pastes are demonstrating excellent electrical and thermal performance for MOSFETS in power QFN packages, and IGBTs in high performance power modules.

© 2012 Ormet Circuits, Inc. phone: 858-831-0010 fax: 858-455-7108

Buy Cheap Arthritis - Indextol (Brand Name Decadron) (Dexamethasone) Buy Arthritis - Indextol (Brand

Decadron is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders. Also it is used in the treatment of cancers of the white blood cells (leukemias), and lymph gland cancers (lymphomas).

Availability: In Stock (34 packs)

Product Description Common use Decadron is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders. Also it is used in the treatment of cancers of the white blood cells (leukemias), and lymph gland cancers (lymphomas). Finally, Decadron is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.

Dosage and direction Take this medication by mouth as directed by your doctor. The initial oral dose is 0.75 to 9 mg daily depending on the disease. The initial dose should be adjusted according to the response to therapy. Take with food or milk to prevent stomach upset. Take this medication by mouth with food or a full glass of water or milk unless your doctor directs you otherwise. If you take this medication once daily, take it in the morning before 9 AM. Use this medication regularly in order to get the most benefit from it. Take it at the same time(s) each day. It is important to continue taking this medication even if you feel well. Follow the dosing schedule carefully, and take this medication exactly as prescribed. Do not stop taking this medication without consulting your doctor. Inform your doctor if your condition does not improve or worsens.

Precautions Do not get immunizations, vaccinations, or skin tests unless specifically directed by your doctor. Before taking Decadron, tell your doctor or pharmacist if you have any allergies, your medical history: active fungal infections, kidney or liver disease, mental/mood conditions, low blood minerals, thyroid disease, stomach/intestinal problems, high blood pressure, heart problems, diabetes, eye diseases, brittle bones, history of blood clots. If you have been taking this medication for a long time, your body may not make enough natural hormones while you are under physical stress. Your dose may need to be adjusted. If you have stopped taking this drug within the past 12 months, you may need to start taking it again if your body is under physical stress. Before having surgery, tell your doctor or dentist that you are using this medication or have taken it within the last 12 months. If you have a history of ulcers or take large doses of aspirin or other arthritis medication. Limit alcoholic beverages while taking this medication to decrease the risk of stomach/intestinal bleeding. If you have diabetes, this drug may make it harder to control your blood sugar levels. Monitor your blood sugar levels regularly and inform your doctor of the results. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this medication. Avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose, chickenpox or measles unless you have previously had these diseases (in childhood). If you are exposed to one of these infections and you have not previously had it, seek immediate medical attention.

Contraindications Do NOT use Decadron if you are allergic to any ingredient in Decadron, you have a systemic fungal infection, you are taking mifepristone. Contact your doctor or health care provider immediately if any of these apply to you.

Possible side effects

Side effects of Decadron depend on the dose, the duration and the frequency of administration. Short courses of dexamethasone usually are well tolerated with few and mild side effects. Long term, high dose dexamethasone usually will produce predictable and potentially serious side effects. Whenever possible, the lowest effective dose of dexamethasone should be used for the shortest possible length of time to minimize side effects. Alternate day dosing also can help reduce side effects. Side effects include fluid retention, weight gain, high blood pressure, loss of potassium, headache, muscle weakness, puffiness, and hair growth on the face, thinning and easy bruising of skin, glaucoma, cataracts, peptic ulceration, worsening of diabetes, irregular menses, growth retardation in children, convulsions, stomach upset, headache, dizziness, menstrual changes, trouble sleeping, increased appetite, or weight gain may occur, depression, euphoria, insomnia, mood swings, personality changes, and even psychotic behavior. A very serious allergic reaction to this drug is rare. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Drug interactions Drugs such as phenobarbital, ephedrine, phenytoin (Dilantin), and rifampin (Rifadin, Rimactane) may increase the breakdown of corticosteroids by the liver. As a result it may be lower blood levels and reduced effects. Therefore, the dose of corticosteroid may need to be increased if treatment with any of these agents is begun.

Missed dose If you are taking this medication daily and on a regular schedule, and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose Seek emergency medical attention if you think you have used too much of this medicine.

Storage Decadron should be stored at 68-77 F (20-25 C) and not frozen

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Plusindol

Antiinflamatorio no esteroideo con acción analgésica.

El ketorolaco está indicado contra el dolor postoperatorio en lugar de los opioides. El ketorolaco cuando se administra por vía intramuscular o intravenosa, no deberá exceder de 5 días. El ketorolaco administrado por vía oral se ha usado para combatir estados de dolor crónico. La administración oral no deberá exceder de 10 días. El fármaco de aplicación local puede ser útil en cuadros inflamatorios del ojo y ha sido probado para el tratamiento de la conjuntivitis alérgica estacional.

FARMACOCIN?TICA Y FARMACODINAMIA

Farmacodinamia: El ketorolaco trometamina es un agente antiinflamatorio no esteroideo, que muestra actividad analgésica, antiinflamatoria y débil actividad antipirética.

El ketorolaco es un miembro del grupo de fármacos antiinflamatorios no esteroideos. Su mecanismo de acción consiste en la inhibición de la ciclooxigenasa y, por consiguiente, de la síntesis de las prostaglandinas. El ketorolaco inhibe la síntesis de prostaglandinas y no tiene ningún efecto sobre los receptores de los opiáceos. Además, no afecta de forma importante al SNC en los animales y carece de propiedades sedantes y ansiolíticas.

El ketorolaco no es un opiáceo ni se ha descrito ningún efecto suyo sobre los receptores centrales para los opioides. Carece de efectos intrínsecos sobre la respiración y no potencia la sedación ni la depresión res­piratoria relacionada con los opioides.

Inyección intramuscular: El ketorolaco se absorbe de forma rápida y completa tras su administración I. M. en voluntarios jóvenes sanos; la concentración plasmática máxima se alcanza a los 50 minutos, por término medio, de una dosis única de 30 mg.

Inyección intravenosa: Tras la administración I. V. en bolo de una dosis única de 10 mg de ketorolaco en voluntarios jóvenes sanos, la concentración plasmática máxima se alcanza al cabo de 5.4 minutos por término medio.

Infusión intravenosa: En voluntarios jóvenes sanos, la concentración plasmática máxima se alcanza unos 5 minutos después de haber finalizado la dosis I. V. inicial de 30 mg; a continuación, la administración de 5 mg/h en infusión continua permite mantener concentraciones plasmáticas similares a las conseguidas con la administración de una inyección de 30 mg cada 6 horas.

Distribución: En voluntarios jóvenes sanos, la farmacocinética del ketorolaco es lineal tras la administración de ketorolaco por vía I. V. o I. M. en dosis únicas o múltiples, o tras su ingestión en las dosis orales recomendadas. El equilibrio de las concentraciones plasmáticas se alcanza después de la cuarta dosis cuando ketorolaco se administra en inyección en bolo I. V. cada 6 horas a voluntarios jóvenes sanos.

Más del 99% del ketorolaco presente en el plasma se halla unido a las proteínas con un volumen medio de distribución de 0.15 l/kg tras la administración de dosis únicas de 10 mg por vía I. V. e I. M. en voluntarios jóvenes sanos.

Eliminación: El ketorolaco y sus metabolitos se eliminan principalmente por vía renal, en torno al 92% de la dosis recuperada en la orina (aproximadamente 40% en forma de metabolitos y 60% restante en forma de ketorolaco inalterado). Con las heces se elimina alrededor del 6% de la dosis administrada. En voluntarios jóvenes sanos, la semivida plasmática terminal de ketorolaco es de 5.3 horas por término medio (intervalo: 2.4-9.2 horas), y la depuración plasmática total de 0.23 l/h/kg, también por término medio.

Al igual que con otros AINEs, ketorolaco está contraindicado en los pacientes con úlcera gastroduodenal activa, hemorragia digestiva reciente, perforación gastrointestinal reciente o antecedentes de úlcera gastroduodenal o hemorragia digestiva.

El ketorolaco está contraindicado en los pacientes con insuficiencia renal moderada o grave (creatinina sérica 442 µmo/l) y en los pacientes con riesgo de insuficiencia renal por hipovolemia o deshidratación.

El ketorolaco está contraindicado durante el parto.

El ketorolaco está contraindicado en los pacientes con hipersensibilidad demostrada al ketorolaco u otros AINEs, así como en pacientes con antecedentes de alergia al ácido acetilsalicílico u otros inhibidores de la síntesis de prostaglandinas, pues se han descrito reacciones anafilactoides graves en estos pacientes. Por su efecto antiagregante plaquetario, ketorolaco está contraindicado como analgésico profiláctico antes de la intervención o durante la intevención quirúrgica, dado el riesgo de hemorragia.

No administrar en niños en el postoperatorio de amigdalectomía.

Úlcera gastroduodenal, hemorragia digestiva y perforación gastrointestinal: Puede lesionarse la mucosa gastrointestinal. En los pacientes tratados con AINEs, pueden presentarse en cualquier momento efectos secundarios graves de tipo digestivo, como irritación gastrointestinal, hemorragia digestiva, ulceración o perforación, en ocasiones sin síntoma previo alguno.

Al igual que sucede con otros AINEs, la incidencia y la gravedad de las complicaciones digestivas aumentan conforme lo hacen la dosis y la duración del tratamiento con ketorolaco. El riesgo de hemorragia digestiva grave depende de la dosis. Esto es especialmente cierto en el caso de los ancianos tratados con dosis medias de ketorolaco superiores a 60 mg/día. La frecuencia de complicaciones gastrointestinales durante el tratamiento con ketorolaco es mayor en los pacientes con antecedentes de úlcera gastroduodenal.

Efectos renales: Al igual que sucede con otros AINEs, ketorolaco debe utilizarse con precaución en los pacientes con insuficiencia renal o antecedentes de neuropatía, dado que se trata de un potente inhibidor de la síntesis de prostaglandinas. Se ha descrito toxicidad renal con ketorolaco y otros AINEs en pacientes con enfermedades causantes de hipovolemia y reducción de flujo sanguíneo renal. Los pacientes con mayor riesgo de padecer esta complicación son los que presentan ya un deterioro de la función renal, hipovolemia, insuficiencia cardiaca o disfunción hepática, así como los pacientes sometidos a tratamiento diurético y los ancianos. La función renal suele regresar a sus valores previos tras suspender el tratamiento con ketorolaco.

El ketorolaco debe utilizarse con gran precaución y estrecho seguimiento en los pacientes con trastornos de la coagulación. Aunque no se ha demostrado ninguna interacción importante entre ketorolaco y la warfarina o la heparina, es posible que el riesgo de hemorragia aumente si ketorolaco se asocia con otros fármacos que afectan a la hemostasia, como la warfarina en dosis terapéuticas, la heparina profiláctica en dosis bajas (2,500-5,000 unidades cada 12 horas) y los dextranos.

Los médicos deben tener presente este posible riesgo de hemorragia en aquellas situaciones en las que la hemostasia es esencial como la resección de próstata, la amigdalectomía o la cirugía estética.

Ancianos: Como sucede con todos los AINEs y todos los fármacos en general, el riesgo de efectos secundarios es mayor en los ancianos que en los pacientes menores de 65 años. En cuanto a las características farmacocinéticas, la semivida plasmática terminal del ketorolaco es más prolongada en los ancianos y la depuración plasmática, menor. Se recomienda situar la dosis en torno al extremo inferior del intervalo posológico habitual.

Capacidad para conducir vehículos y utilizar maquinaria: Algunos pacientes pueden experimentar somnolencia, mareo, vértigo, insomnio o depresión durante el tratamiento con ketorolaco.

Pacientes de edad avanzada: En pacientes de edad avanzada (mayores de 65 años) la vida media se prolonga y la depuración se reduce.

Se recomienda utilizar la menor dosis del intervalo de dosificación. La incidencia de complicaciones gastrointestinales aumenta con el incremento en la dosis y duración del tratamiento.

RESTRICCIONES DE USO DURANTE EL EMBARAZO Y LA LACTANCIA

No se recomienda el uso de ketorolaco durante el embarazo o el parto. Tampoco se recomienda durante la lactancia.

No se han apreciado signos de teratogenia tras administrar dosis tóxicas de ketorolaco a ratas y conejas preñadas. En las ratas se observó una prolongación de la gestación y un retraso del parto. El ketorolaco atraviesa en 10% la barrera placentaria. Se ha detectado también en pequeñas concentraciones en la leche materna.

REACCIONES SECUNDARIAS Y ADVERSAS

Los pacientes tratados con ketorolaco pueden presentar los siguientes efectos secundarios:

Tubo digestivo: Dolor abdominal, molestias abdominales, anorexia, estreñimiento, diarrea, dispepsia, eructos, flatulencia, sensación de plenitud, gastritis, hemorragia digestiva, hematemesis, náuseas, esofagitis, pancreatitis, úlcera gastroduodenal, perforación gástrica o intestinal, estomatitis, vómitos, rectorragia, me­lena.

Sistema nervioso central y aparato locomotor: Sueños anormales, alteración del pensamiento, ansiedad, meningitis aséptica, convulsiones, depresión, mareo, somnolencia, sequedad de boca, euforia, polidipsia, alucinaciones, cefalea, hipercinesia, disminución de la capacidad de concentración, insomnio, mialgia, nerviosismo, parestesias, reacciones psicóticas, sudación, vértigo.

Aparato urinario: Insuficiencia renal aguda, dolor de riñones (con hematuria e hiperazoemia o sin ellas), síndrome hemolítico urémico, hiperpotasemia, hiponatremia, polaquiuria, retención urinaria, nefritis intersticial, síndrome hemolítico urémico, hiperpotasemia, hiponatremia, polaquiuria, retención urinaria, nefritis intersticial, síndrome nefrótico, oliguria, elevación de las concentraciones séricas de urea creatinina.

Al igual que sucede con otros inhibidores de la síntesis de prostaglandinas, pueden aparecer signos de insuficiencia renal (por ejemplo, elevación de las concentraciones de creatinina y potasio).

Aparato respiratorio: Asma bronquial, diseña, edema pulmonar.

Órganos de los sentidos: Disgeusia, alteraciones de la vista, acúfenos, hipoacusia.

Otros efectos secundarios: Astenia, edema, reacciones en el lugar de la inyección, aumento de peso, ­fiebre.

INTERACCIONES MEDICAMENTOSAS Y DE OTRO G?NERO

El riesgo de efectos secundarios graves relacionados con los AINEs puede estar aumentado en caso de tratamiento simultáneo con ácido acetilsalicílico u otros AINEs.

El riesgo de hemorragia aumenta cuando ketorolaco se asocia a la pentoxifilina.

Con la administración simultánea de probenecid se ha descrito una disminución de la depuración plasmática y el volumen de distribución del ketorolaco, así como un aumento de su concentración plasmática y su semivida.

Algunos inhibidores de la síntesis de prostaglandinas disminuyen el aclaramiento del metotrexato y podrían potenciar su toxicidad.

Algunos inhibidores de la síntesis de prostaglandinas disminuyen el aclaramiento renal del litio y aumentan su concentración plasmática.

El ketorolaco no altera la fijación de la digoxina a las proteínas plasmáticas. Las concentraciones terapéu­ticas de digoxina, warfarina, ibuprofeno, naproxeno, piroxicam, paracetamol, fenitoína y tolbutamida no alteran la fijación del ketorolaco a las proteínas plasmáticas.

Aunque no se ha demostrado ninguna interacción importante, ketorolaco y la warfarina o la heparina, es posible que el riesgo de hemorragia aumente.

ALTERACIONES EN LOS RESULTADOS DE PRUEBAS DE LABORATORIO

Efectos renales: Pueden presentarse elevaciones del nitrógeno de urea y la creatinina sérica como signos de daño renal. En los pacientes con deterioro significativo de la función renal, la administración queda a criterio del médico.

Se puede precipitar insuficiencia renal aguda en pacientes hipovolémicos o en pacientes con volumen circulante efectivo disminuido.

Efectos hematológicos: El ketorolaco inhibe la agregación plaquetaria y prolonga el tiempo de sangrado. La administración concomitante de anticoagulantes, incluyendo dosis bajas de heparina y warfarina, pueden incrementar el riesgo de sangrado postoperatorio.

Efectos hepáticos: Pueden presentarse elevaciones de una o más pruebas de la función hepática. Estas anormalidades pueden progresar, permanecer inalteradas o ser transitorias mientras se continúa el tratamiento.

PRECAUCIONES EN RELACI?N CON EFECTOS DE CARCINOG?NESIS, MUTAG?NESIS, TERATOG?NESIS Y SOBRE LA FERTILIDAD

No existen reportes de ketorolaco asociado con tumorogenicidad ni mutagenicidad y no demostró potencial teratogénico.

DOSIS Y V?A DE ADMINISTRACI?N

Intramuscular e intravenosa.

Duración del tratamiento: En los adultos, el tratamiento con inyecciones en bolos I. V. o I. M. no debe superar en total los 4 días, pues los efectos secundarios aumentan con su uso prolongado. En los niños, el tratamiento con inyecciones en bolo I. V. o I. M. de ketorolaco no debe superar en total los 2 días.

Cuando se administra en inyección en bolo I. V. ésta debe durar como mínimo 15 segundos. La inyección I. M. debe aplicarse en forma lenta y profunda.

Administración I. M.: La dosis recomendada es de 30 mg 4-6 horas, sin sobrepasar la dosis diaria máxima de 120 mg.

Inyección rápida: 15 mg cada 6 horas, sin sobrepasar la dosis diaria máxima de 60 mg.

MANIFESTACIONES Y MANEJO DE LA SOBREDOSIFICACI?N O INGESTA ACCIDENTAL

Con la sobredosis de ketorolaco se han descrito los siguientes síntomas: dolor abdominal, náuseas, vómito, hiperventilación, úlcera gastroduodenal, gastritis erosiva y disfunción renal; todos ellos desaparecieron tras retirar el fármaco. La diálisis apenas permite eliminar el ketorolaco de la sangre.

Brompheniramine Medlineplus Drug Information, Mepramin

Brompheniramine

FDA Intends to Remove Some Unapproved Cough, Cold, and Allergy Drugs from the Market

This safety alert does not apply to this medication, but only to some products which contain this medication. In addition, it is important that you know that there is not a problem with most of the products described in this medication monograph. And some drug companies may decide to seek full approval from the FDA so that they can continue marketing their products.

On March 2, 2011, the Food and Drug Administration (FDA) issued a safety alert about certain unapproved prescription cough, cold, and allergy products containing this drug in combination with other drugs. These products are not currently approved by the FDA for safety, effectiveness, and quality. FDA asked drug companies to stop shipping most of these products for sale in the US within the next 6 months. Although some of these products have been marketed for many years, laws about what a company must prove to FDA for drug product approval have gotten tougher and increased enforcement of these laws is now taking place. The FDA took this action due to concerns about certain potential risks associated with use of these medications. These risks may include:

the possibility of improper use in infants and young children

potentially risky combinations of ingredients

patients receiving too much or too little of the medication because of problems with the way some ''timed-release'' products are made

If you are concerned that the prescription cough, cold, and allergy medication you are taking is not approved by the FDA, you should talk to your doctor or pharmacist. If the medication you are taking is not approved, your doctor can prescribe another prescription medication or your doctor or pharmacist can suggest an over-the-counter (OTC) cough, cold, and allergy product for your condition. There are many safe and effective alternative approved products that can be taken instead. Your doctor probably prescribed the medicine without knowing that FDA had not approved it. This is because it has been so difficult for doctors and pharmacists to find out that these products are unapproved. For additional information:

You can visit the FDA website (http://www. fda. gov/ForConsumers/ConsumerUpdates/ucm244852.htm ) for more information about this action to remove unapproved cough, cold, and allergy products from the market.

You can find a list of unapproved products by going to (http://goo. gl/Gqc7d ).

For information on how to dispose of unused products, go to http://www. fda. gov/ForConsumers/ConsumerUpdates/ucm101653.htm .

Why is this medication prescribed?

Brompheniramine relieves red, irritated, itchy, watery eyes; sneezing; and runny nose caused by allergies, hay fever, and the common cold. Brompheniramine helps control symptoms, but does not treat the cause of the symptoms or speed recovery. Brompheniramine should not be used to cause sleepiness in children. Brompheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

How should this medicine be used?

Brompheniramine comes in combination with other cough and cold medications as a chewable tablet, an extended-release (long-acting) capsule, an extended-release (long-acting) tablet, and a liquid to be taken by mouth. The chewable tablet and liquid are usually taken every 4 to 6 hours as needed. The extended-release tablets and capsules are usually taken every 8 or 12 hours as needed. Follow the directions on the package label or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take brompheniramine exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor.

Brompheniramine comes in combination with other cough and cold medications. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before taking two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.

Nonprescription cough and cold combination products, including products that contain brompheniramine, can cause serious side effects or death in young children. Do not give these products to children younger than 6 years of age. If you give these products to children 6-11 years of age, use caution and follow the package directions carefully.

If you are giving a product that contains brompheniramine to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give brompheniramine products that are made for adults to children.

Before you give a brompheniramine product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child's age on the chart. Ask the child's doctor if you don't know how much medication to give the child.

If you are taking the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

If you are taking the extended-release tablets or capsules swallow them whole; do not crush, break, or chew them.

Stop taking brompheniramine and call your doctor if your symptoms last longer than 7 days or if you have a fever.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking brompheniramine,

tell your doctor and pharmacist if you are allergic to brompheniramine or any other medications.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: medications for colds, hay fever, or allergies; medications for depression or seizures; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); muscle relaxants; narcotic medications for pain; sedatives; sleeping pills; and tranquilizers.

tell your doctor if you have or have ever had asthma, emphysema, chronic bronchitis, or other breathing problems; glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision); ulcers; difficulty urinating (due to an enlarged prostate gland); heart disease; high blood pressure; seizures; or an overactive thyroid gland.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking brompheniramine, call your doctor.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking brompheniramine.

you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

talk to your doctor about the safe use of alcohol while you are taking brompheniramine. Alcohol can make the side effects of brompheniramine worse.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Brompheniramine is usually taken as needed. If your doctor has told you to take brompheniramine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Brompheniramine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

drowsiness

dry mouth, nose, and throat

nausea

headache

chest congestion

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

vision problems

difficulty urinating

Brompheniramine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

Our Achievements, Analac

Our achievements

King Khalid Award for the construction of a human and community development under the auspices of His Royal Highness Prince / Nayef bin Abdulaziz Al Saud.

King Faisal International Prize sponsored by His Royal Highness Prince / Nayef bin Abdulaziz Al Saud.

The first Saudi fair for employment (Together For You ) under the auspices of His Royal Highness Prince / Salman bin Abdulaziz Al Saud.

The first Women employment Fair sponsored by Her Royal Highness Princess / Fahda Saud Al-Saud, head of the (Al Faisaliah charity association.)

King Faisal Specialist Hospital (The Saudi International Conference of Nephrology & Transplantation) for the year 2011, under the auspices of His Royal Highness Prince / Salman bin Abdulaziz Al Saud.

King Abdullah bin Abdulaziz Al Saud The Custodian of the Two Holy Mosques ceremony for Scholarship (for training technicians ) under the auspices of His Excellency the Minister of Education and Higher Education Dr. / Khalid bin Mohammed Al-Angari.

The ceremony of Riyadh Radio under the auspices of His Excellency the Minister of Information Dr. / Abdel Aziz Khoja Mohieldin.

Military hospital the event of the 11 International endoscopy Conference under the auspices of the Director of the military hospital in the Central Region, General doctor / Khalf ben rdn Almetiry .

The elections of Literary clubs at the Ministry of Culture and Media under the auspices of His Excellency Dr. / Nasser Hujaylan Undersecretary for Cultural affair

Information Technology Ceremony for the universities in Saudi Arabia under the auspices of His Excellency the Minister of Higher Education Dr. / Khalid bin Mohammed Al-Angari.

King Saud University Elections under the auspices of the university Rector.

The Ceremony of (Commission for the Promotion of Virtue and Prevention of Vice) under the auspices of the General - Director of the bodies in Riyadh.

Occasion of the Arab Conference for Development and Planning of the Arab leadership and supervisory and technical skills in management and planning the cities and municipalities and assess its performance in association with Batra conference in Jordan.

Medical conferences for Novartis international company .

International Exhibition Conference on Higher Education.

Ceremony of the Institute of Banking.

Travel Clothing How To Choose - Rei Expert Advice, Travelmin

Travel Clothing: How to Choose

Occasional travelers often ask: "What should I wear? And, "how many clothes should I bring?"

Packing clothing for a big trip may seem overwhelming at first, but packing smart can alleviate unnecessary stress. When traveling, especially to another country, it's best to pack a few lightweight clothing items that work for every kind of adventure—from city touring to wilderness exploring.

This article gives you the basics on how to shop and pack.

Travel Clothing 101

The key to packing smart is to find a few key pieces you can wear virtually anywhere and during any time of day. Look for:

Performance fabrics: Fabrics that are breathable, moisture wicking and easy care make smart choices for traveling. See our fabric comparison, below.

Neutral colors: Luggage space is precious. Ditch the bright colors and pack neutral—brown, black and khaki—especially for pants, shorts and skirts. These colors coordinate well with everything, so you can pack less.

Wrinkle resistance: Look for garments touted as wrinkle-resistant. This doesn't mean wrinkle-free, but they should at least wrinkle less than other garments.

Subtle styling: Standing out from the local culture usuallly can't be helped, but the clothing you wear can make you feel less conspicuous. Avoid tight clothing or very short shorts and skirts. This type of clothing might not be acceptable in some cultures or venues.

Sun protection: All fabrics block UV rays to some degree, but sun-protection clothing features an ultraviolet protection factor (UPF) rating against both UVA and UVB rays. A garment with a UPF of 50 blocks 98% of UV rays. Sun-protection garments are rated from 15 (good) to 50+ (excellent), and this protection never washes off or sweats away. For details, see the REI Expert Advice article, Sun Protection Clothing Basics.

Insect protection: Bugs can be a real nuisance. Worse, in some areas, West Nile virus, Lyme disease, dengue fever, malaria or encephalitis can be genuine concerns. A few clothing lines, such as the ExOfficio ® Insect Shield collection, are treated with permethrin, an insecticide engineered specifically for fabrics, to protect your skin from insects. Effective against ticks, mosquitoes and dozens of other insects, permethrin has been safely used for decades and its use is recommended by the CDC (Centers for Disease Control and Prevention). You can also apply permethrin in spray form to your other clothing and gear.

Pockets: These become especially useful when you're packing just a few shirts and pants for a trip. A few tips:

Shirt pockets: Best for tickets, sunglasses or other small items.

Pants and skirt pockets: Some incorporate hidden passport or money pockets, which can be more comfortable than wearing a separate money belt under your clothing.

Zippered pockets: These offer better security from loss or theft than button closures.

Comparing Fabrics

Fabrics should breathe well, wick moisture away from your skin and dry quickly. Cotton, while OK for casual wear, is generally less suited for traveling than the fabrics listed below. Your most common choices:

Nylon and polyester: Most performance fabrics feature either of these synthetics. Some name brands include CoolMax ® polyester or Cordura ® nylon.

Pros: Breathable, lightweight, wicks away moisture and dries quickly, resists pilling and abrasion.

Cons: Slightly less forgiving feel than cotton.

Tencel ® and polynosic rayons: Tencel is a brand name for lyocell, a wood-pulp-based fiber that is part of the rayon family. Tencel and polynosic rayons offer similar drape and comfort, plus both offer machine wash/dry convenience. (Note: A similar fabric, viscose rayon, is typically dry clean only, so check the care instructions to be sure.)

Pros: Silky smooth feel, dries quickly and resists wrinkles; Tencel is made using an environmentally friendly process.

Cons: Doesn't wick away moisture as well as polyester or nylon.

Silk: Luxuriously soft, it's most often used in underwear.

Pros: Lightweight, breathable, durable—ideal for warm climates.

Cons: Less durable than other materials.

Cotton: This is commonly used for casual, all-around styles.

Pros: Soft, durable, breathable, versatile styling and easy care

Cons: Doesn't wick away moisture or dry as fast as nylon or polyester

Cotton/polyester blend: Another common fabrication for casual wear, this blend seeks to offer both comfort and performance.

Pros: Feels soft against skin, breathable

Cons: Doesn't wick away moisture or dry as fast as 100% nylon or polyester

Plated fabrics: "Plated" refers to garments with one fabric (e. g. cotton) on the outside face, backed with another fabric type (e. g. polyester) against the skin. This approach is designed to offer the best attributes of both fabrics.

Travel Clothing Review

Always bring a hat. Your choices:

Rain hats feature a wide brim, waterproof/breathable construction and a chin strap. They also double as sun protection.

Sun hats are usually cotton or nylon for breathability and have grommets or mesh for ventilation. Some styles feature a cape to keep sun off your neck and ears.

Casual hats include ball caps and trekking hats. A wider brim will provide better protection from sun and rain.

Underwear and Socks

The same fabric rules apply for underwear and socks: A synthetic fabric is easier to care for than cotton, while merino wool products offer natural breathability and comfort. When choosing socks, know that synthetics and wool can help prevent blisters by keeping feet drier than cotton socks do.

Get organized: Use lightweight packing cubes (right) to keep socks and underwear separate from shirts and toiletries. They are available in multiple sizes.

Be neat: Packing folders keep clothing looking pressed while traveling. Some can hold up to 15 garments.

Avoid wrinkles: Another way to avoid wrinkles in your pants and dresses is by folding them at the knees. Try this technique: Place the top half of your pants and/or dresses inside your luggage with the bottom half draped outside. When all garments are stacked inside your luggage, fold the bottom of the garments at the knees back into the luggage.

Smell fresh: Place a scented dryer sheet or incense bag in between a few layers of clothing while you're packing. Doing this will keep your clothes smelling fresh and clean during the entire trip.

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Bupron Sr, Depnox

Common use Bupron SR is an atypical antidepressant that helps in treating depression, obesity, smoking cessation. The last is achieved by decreasing cravings and withdrawal effects of nicotine. The medication may also be used to treat attention deficit hyperactivity disorder (ADHD and bipolar disorder (depressive phase). This medicine can be also applied for other purposes. It contains active ingredient bupropion hydrochloride which restores natural balance of neurotransmitters in the brain.

Dosage and direction

Take Bupron SR by mouth with a glass of water, with or without food. Take the drug only as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing or chewing this medicine. Each dose should be taken at least six hours apart. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you.

Precautions Before taking Bupron SR tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have bipolar confusion, eye, liver or kidney problems. Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to side effects of the medicine. During pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.

Bupron SR should not be used by pregnant/nursing women or children as well as by the patients having demonstrated a reaction of hypersensitivity to Bupron SR.

Possible side effect The most common side effects are dry mouth, constipation, sedation, increased appetite, rapid or irregular heartbeat, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you used before using this medication. Bupron SR can interact with: * MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc. * antiarrhythmics * antipsychotics * selective serotonin reuptake inhibitors (SSRIs). Turn to your doctor or pharmacist for more details.

Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.

Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include nausea, irregular heartbeat, chest pain, and feeling light-headed or fainting.

Store your medicines at room temperature between 68-77 F (20-25 C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from children and pets.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use Bupron SR is an atypical antidepressant that helps in treating depression, obesity, smoking cessation. The last is achieved by decreasing cravings and withdrawal effects of nicotine. The medication may also be used to treat attention deficit hyperactivity disorder (ADHD and bipolar disorder (depressive phase). This medicine can be also applied for other purposes. It contains active ingredient bupropion hydrochloride which restores natural balance of neurotransmitters in the brain.

Dosage and direction

Take Bupron SR by mouth with a glass of water, with or without food. Take the drug only as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing or chewing this medicine. Each dose should be taken at least six hours apart. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you.

Precautions Before taking Bupron SR tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have bipolar confusion, eye, liver or kidney problems. Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to side effects of the medicine. During pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.

Bupron SR should not be used by pregnant/nursing women or children as well as by the patients having demonstrated a reaction of hypersensitivity to Bupron SR.

Possible side effect The most common side effects are dry mouth, constipation, sedation, increased appetite, rapid or irregular heartbeat, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you used before using this medication. Bupron SR can interact with: * MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc. * antiarrhythmics * antipsychotics * selective serotonin reuptake inhibitors (SSRIs). Turn to your doctor or pharmacist for more details.

Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.

Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include nausea, irregular heartbeat, chest pain, and feeling light-headed or fainting.

Store your medicines at room temperature between 68-77 F (20-25 C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from children and pets.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Victoria Yudin, Vudin

I often surprise people by telling them to change the void dates when they void Payables transactions in Dynamics GP. If you’re voiding something that was just entered, leaving the defaulted dates is usually fine. However, when you are voiding an old check because you’re going to re-issue it, you typically want to void using the same date as the re-issued check (or at least in the same month), so there is a zero net change for both the subledger and the General Ledger. And if the original dates are in a closed year, it is even more important to not change prior year numbers.

The problem is that the window where you enter the void is a bit counter-intuitive and does not make it look like you can change the dates. But you can! Both the Void Date (the subledger void date) and the Posting Date (the General Ledger void date) can be changed simply by clicking on the date in the grid and changing it.

Now you know – don’t forget to change the void dates as needed next time.

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A lot of the requests I get are for actual vs. budget reporting. Certainly FRx and Management Reporter can do this pretty easily, but more and more I see users wanting this in Excel with a refreshable report. This blog post will give you everything you need to create a refreshable Excel report that shows monthly and YTD actual vs. budget for every account when you select a year, month (period for those not on a calendar fiscal year) and budget ID.

Here is a screenshot of the results (click on the image to make it bigger):

My example uses ‘month’, but you can easily adapt this to your fiscal calendar as needed. As an added bonus, if you’re using GP Reports Viewer you can set this up to run inside Dynamics GP.

The SQL stored procedure below.

This Excel file .

Either GP Reports Viewer to set this up inside Dynamics GP or some additional permissions to set this up in Excel for your users.

Here is the code for the SQL stores procedure:

Disclaimer: I tested this on limited data, if you find an issue or have a suggestion for improvement, please let me know and I will post the update here for everyone.

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Indinavir Medlineplus Drug Information, Crixivan

Indinavir

Indinavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Indinavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood. Although indinavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other life-style changes may decrease the risk of transmitting the HIV virus to other people.

How should this medicine be used?

Indinavir comes as a capsule to take by mouth. It is usually taken every 8 hours (three times a day). Take indinavir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take indinavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take indinavir on an empty stomach, 1 hour before meals or 2 hours after meals, with water, skim or nonfat milk, juice, coffee, or tea. However, if indinavir upsets your stomach, it may be taken with a light meal, such as dry toast or cornflakes with skim or nonfat milk. Talk to your doctor or pharmacist about what foods may be taken with indinavir.

Continue to take indinavir even if you feel well. Do not stop taking indinavir without talking to your doctor.

Your doctor may need to interrupt your treatment if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with indinavir.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Other uses for this medicine

Indinavir is also used sometimes in combination with other medications to treat healthcare workers and other individuals exposed to HIV infection after accidental contact with HIV-contaminated blood, tissues, or other body fluids. Talk to your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow?

Before taking indinavir,

tell your doctor and pharmacist if you are allergic to indinavir, any other medications, or any of the ingredients in indinavir capsules. Ask your pharmacist for a list of the ingredients.

tell your doctor if you are taking any of the following medications: alfuzosin (Uroxatral); alprazolam (Xanax); amiodarone (Cordarone, Nexterone, Pacerone); cisapride (Propulsid) (not available in the U. S.); ergot-type medications such as dihydroergotamine (D. H.E. 45, Migranal), ergonovine (Ergotrate), ergotamine (Ergomar, in Cafergot, in Migergot), and methylergonovine (Methergine); lovastatin (Altoprev, Mevacor, in Advicor); midazolam (Versed) by mouth; pimozide (Orap); sildenafil (only Revatio brand used for lung disease); simvastatin (Zocor, in Simcor, in Vytorin); or triazolam (Halcion). Your doctor will probably tell you not to take indinavir.

tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: bosentan (Tracleer); calcium-channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), felodipine (Plendil), nicardipine (Cardene), and nifedipine (Adalat, Afeditab, Procardia); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, others); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet, in Liptruzet) and rosuvastatin (Crestor); clarithromycin (Biaxin, in PrevPac); colchicine (Colcrys, Mitigare); dexamethasone; fluticasone (Flonase, Flovent, in Advair); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); other medications for HIV including atazanavir (Reyataz, in Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, in Atripla), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra, in Viekira Pak), and saquinavir (Invirase); medications for irregular heartbeat such as lidocaine (Glydo, Xylocaine) and quinidine (in Nuedexta); medications that suppress the immune system such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune, Torisel), and tacrolimus (Astagraf XL, Prograf); midazolam (Versed) by injection; certain phosphodiesterase inhibitors (PDE-5 inhibitors) used for erectile dysfunction such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra, in Staxyn); phenobarbital; phenytoin (Dilantin, Phenytek, others); quetiapine (Seroquel); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); salmeterol (Serevent, in Advair); trazodone; and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with indinavir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

tell your doctor what herbal products you are taking, especially St. John's wort.

if you are taking didanosine (Videx), take it at least one hour before or after indinavir.

tell your doctor if you have or have ever had hemophilia (bleeding disorder in which the blood does not clot properly), diabetes, or kidney or liver disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking indinavir, call your doctor. You should not breast-feed if you are infected with HIV or if you are taking indinavir.

you should know that your body fat may increase or move to different areas of your body such as your breasts, upper back, neck, chest, and stomach area. Loss of fat from the legs, arms, and face can also happen.

you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. Tell your doctor immediately if you have any of the following symptoms while you are taking indinavir: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar that is not treated can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include: dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms at anytime during your treatment with indinavir, be sure to tell your doctor.

What special dietary instructions should I follow?

Drink at least 48 ounces (1.5 liters), which is approximately six 8-ounce (240-milliliter) glasses, of water or other liquids every 24 hours.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

What should I do if I forget a dose?

If you miss a dose by less than 2 hours, take the missed dose as soon as you remember it. However, if you miss a dose by more than 2 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Indinavir may cause side effects. Tell your doctor if this symptom is severe or does not go away:

change in sense of taste

Indinavir may cause side effects. Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

rash

hives

itching

peeling or blistering skin

back pain

pain in the side of your body

middle to lower stomach pain

blood in urine

muscle pain or weakness

nausea

excessive tiredness

unusual bleeding or bruising

loss of appetite

pain in the upper right part of your stomach

flu-like symptoms

dark yellow or brown urine

yellowing of the skin or eyes

shortness of breath

fast heartbeat

confusion

dizziness

headache

paleness

Indinavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. A desiccant (drying agent) is included with your capsules; keep this in your medicine bottle at all times. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the following:

pain in the side of your body

blood in urine

nausea

vomiting

diarrhea

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to indinavir.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

Oxetol 150mg Tablet ( Sun ) - Buy Oxetol 150mg Tablet Online At Best Price In India, Oxetol

OXETOL 150MG TABLET

It is used to stop or control seizures. It is used to treat painful nerve diseases. It is used to treat manic low mood (depression).

How does Oxcarbazepine work:

Oxcarbazepine calms the brain. It helps steady mood.

How should Oxcarbazepine be used:

Take as you have been told, even if you are feeling better. This drug may be used with other seizure drugs. Take with or without food. Take with food if it causes an upset stomach.

Common side effects of Oxcarbazepine :

Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Change in balance. Headache. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Unsafe allergic effects may rarely happen.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Oxcarbazepine :

If you have an allergy to oxcarbazepine or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. Change in thinking clearly and with logic. Sudden change in eyesight, eye pain, or irritation. Very bad headache. Very upset stomach or throwing up. Feeling very tired or weak. Seizures that change or get worse. Yellow skin or eyes. Any bruising or bleeding. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Oxcarbazepine with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

How do I store Oxcarbazepine :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

It is used to stop or control seizures. It is used to treat painful nerve diseases. It is used to treat manic low mood (depression).

Ampliar - Diccionario Ingles-Espanol, Ampliar

Online Language Dictionaries

ampliar horario loc verb locucion verbal . Unidad lexica estable formada de dos o mas palabras que funciona como verbo ("sacar fuerzas de flaqueza", "acusar recibo").

(trabajar mas horas)

extend working hours v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

expand the schedule v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

ampliar su vocabulario loc verb locucion verbal . Unidad lexica estable formada de dos o mas palabras que funciona como verbo ("sacar fuerzas de flaqueza", "acusar recibo").

widen your vocabulary v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

ampliar sus conocimientos en algo loc verb locucion verbal . Unidad lexica estable formada de dos o mas palabras que funciona como verbo ("sacar fuerzas de flaqueza", "acusar recibo").

(estudiar a fondo)

increase your knowledge of [sth] v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

increase your understanding of [sth] v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

ampliar sus horizontes loc verb locucion verbal . Unidad lexica estable formada de dos o mas palabras que funciona como verbo ("sacar fuerzas de flaqueza", "acusar recibo").

widen your horizons v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

broaden your horizons v expr verbal expression . Phrase with special meaning functioning as verb--for example, "put their heads together," "come to an end."

International Drug Names From, Purgo Pil

International Drug Names

The Drugs. com International Drug Name Database contains information about medications found in 185 countries around the world. The database contains more than 40,000 medication names marketed outside the USA and is presented in multiple languages.

Many of the medications listed here are marketed under different names in different countries. Country and region specific information is shown where available. Please note that some medications may also be available in countries not specified.

See also: Medications marketed in the USA and the UK .

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Drugs. com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Sep 2nd, 2016), Cerner Multum™ (updated Sep 5th, 2016), Wolters Kluwer™ (updated Aug 8th, 2016) and others. To view content sources and attributions, please refer to our editorial policy .

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Precor Home Fitness, Procor

Your Home

INTRODUCING THE NEXT GENERATION OF TREADMILLS AND EFX® ELLIPTICALS

Incredible design and commercial-grade parts create the smooth and natural feel that has made Precor a favorite in health clubs all over the world. New touch consoles, convenience features and integration with the Preva® network fitness app give you a personalized workout experience second only to a personal trainer. Now, it’s easier than ever to get a health club quality workout at home.

Experience the performance and feel of the new Precision® and Energy® Series treadmills and EFX® Ellipticals at our network of Authorized Dealers. Our authorized retailers have the expertise and training to assure that you find the right equipment for your fitness goals and budget.

Find an Authorized Precor Dealer

Strike the pace that feels right for you. Our treadmills adjust for the natural fluctuations in your stride and always provide a stable, low-impact running surface. Shop Treadmills

Ease into a low-impact stride with our patented EFX motion, and target a variety of muscle groups with our exclusive CrossRamp® technology. You'll find these features on all of our Precor ellipticals. Shop Ellipticals

Change your workouts at will, just by moving naturally. With the AMT you can go from short to long strides, walking to running, climbing to lunging. Move smoothly, easily, and spontaneously. Shop AMT

Enjoy total comfort on the same bikes found in health clubs worldwide. Providing low-impact and non-weight-bearing exercise, our bikes are easy to use and will help keep your workouts fresh. Shop Bikes

Find an Authorized Precor Dealer

Clindana, Clindana

Product Description Common use Cleocin kills sensitive bacteria by stopping the production of essential bacterial proteins after binding a bacterial ribosome. Cleocin is close by its qualities to Lincomycin. Lincosamides are usually used to treat staphylococci and streptococci. Cleocin is administered to treat protozoal diseases such as malaria, infections of respiratory system, skin and soft tissures, bones and joints, abdominal organs, and others. It does not treat meningitis.

Dosage and directions Take orally four times a day with or without food with a full glass of water. Take Cleocin at evenly spaced intervals.

Precautions This medication should be used only for treatment of serious bacterial infections due to its ability to cause severe and even fatal intestinal condition known as pseudomembranous colitis. This condition may appear during treatment or even weeks after treatment has stopped. So if you have persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool do not use anti-diarrhea drugs and inform your doctor about your condition.

Contraindications Do not take this drug if you have antibiotic-associated colitis, Crohn disease, ulcerative colitis or meningitis, have allergy to Cleocin or Lincomycides. Inform your doctor if you are pregnant or breastfeeding, if you have diarrhea, a history of liver problems or stomach or bowel problems before taking this medication.

Possible side effect Mild diarrhea, nausea, vomiting or upset stomach may occur. If they persist or become bothersome contact your doctor. Seek medical attention right away if you have serious signs of allergy (hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face) or other side effects: bloody or tarry stools, decreased urination, severe stomach cramps or pain, unusual vaginal discharge, yellowing of the skin or eyes.

Inform your doctor about all drugs you are taking and especially about erythromycin, kaolin-pectin, live bacterial vaccines. Clindamycin may increase the effects of drugs used during surgery so your doctor should know if you are taking Cleocin and plan to be operated.

Missed dose Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose Cleocin overdose may cause serious consequences, so in case of persistent symptoms of abdominal pain, nausea, vomiting, and diarrhea contact your doctor.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Tixylix 60ml Linctus Price, Side-Effects, Uses Generic-Alternatives & Dosage Of Tixylix 60ml Linctus

LIPAGLYN 4 mg. Pack of 10 Tablets

Side Effects of Tixylix 60ml Linctus:

CNS depression, paradoxical excitation in childn, dryness of mouth, blurring of vision, retention of urine, constipation, glaucoma, tachycardia, headache, hypotension, tinnitus.

Drug Interactions of Tixylix 60ml Linctus:

Masks ototoxicity of aminoglycoside antibiotics. May enhance the sedative effects of CNS depressants like alcohol, hypnotics, barbiturates and opioids. Potentially Fatal: Ventricular arrhythmias when used with drugs that prolong QT interval.

Contraindications of Tixylix 60ml Linctus:

Hypersensitivity, coma, porphyria, cardiac disease, hypokalaemia, intra-arterial or SC inj, neonates and young children, pregnancy, lactation.

Mechanism of Action of Tixylix 60ml Linctus:

Promethazine, a phenothiazine derivative, blocks postsynaptic dopaminergic receptors in the brain and has a strong ?-adrenergic blocking effect. It competitively binds to H1-receptors. Absorption: Well absorbed (Oral, IM); peak plasma concentrations after 2-3 hr. Distribution: Widely distributed: Brain, crosses the placenta, enters breast milk. Protein-binding: 76-93%. Metabolism: Extensive hepatic 1st-pass metabolism; converted to promethazine sulfoxide, N-desmethylpromethazine. Excretion: Via urine and bile (as metabolites); 5-14 hr (elimination half-life).

Special Precautions for Tixylix 60ml Linctus:

Elderly, glaucoma, epilepsy, CVS disease, impaired liver function, asthma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction. May cause drowsiness. For parenteral admin: Drug must be administered carefully and slowly; incorrect admin can lead to severe tissue injury.

Categories

Buy Roxifen Online - Self Healing Centre, Roxifen

Roxifen

Medication guide about Roxifen (Piroxicam)

Brand name: Roxifen Generic name: Piroxicam

What is the most important information I should know about Roxifen? Take Roxifen with food, milk, or an antacid to lessen stomach upset. Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous. Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to Roxifen (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist. Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, Roxifen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking Roxifen if you drink more than 3 alcoholic beverages a day.

What is Roxifen? Roxifen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Roxifen works by reducing hormones that cause inflammation and pain in the body. Roxifen is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis. Roxifen may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking Roxifen? Before taking this medication, tell your doctor if you have an allergy to aspirin or any other NSAIDs, have an ulcer or bleeding in your stomach, drink more than three alcoholic beverages a day, have liver disease, have kidney disease, have a coagulation (bleeding) disorder, have congestive heart failure, have fluid retention, have heart disease, or You may not be able to take Roxifen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. It is not known whether Roxifen will be harmful to an unborn baby. Roxifen should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby’s heart. Do not take Roxifen without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Roxifen passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Roxifen? Take Roxifen exactly as directed. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take Roxifen with food, milk, or an antacid to lessen stomach upset. Store Roxifen at room temperature away from moisture and heat.

What happens if I miss a dose? If you are taking Roxifen on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose. If you are taking Roxifen as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose? Seek emergency medical attention if an overdose is suspected. Symptoms of a Roxifen overdose include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

What should I avoid while taking Roxifen? Avoid prolonged exposure to sunlight. Roxifen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, Roxifen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking Roxifen if you drink more than 3 alcoholic beverages a day. Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to Roxifen (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of Roxifen? Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous. If you experience any of the following serious side effects, stop taking Roxifen and seek medical treatment or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); muscle cramps, numbness, or tingling; ulcers (open sores) in the mouth; rapid weight gain (fluid retention); seizures; decreased hearing or ringing in the ears; yellowing of your skin or eyes (jaundice); or abdominal cramping, heartburn, or indigestion. Other, less serious side effects may be more likely to occur. Continue to take Roxifen and talk to your doctor if you experience dizziness or headache; nausea, diarrhea, or constipation; depression; fatigue or weakness; dry mouth; or irregular menstrual periods. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Roxifen? Before taking Roxifen, tell your doctor if you are taking any of the following drugs: aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan’s, others); another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), oxaprozin (Daypro), naproxen (Aleve, Anaprox, Naprosyn, Naprelan, others), sulindac (Clinoril), or tolmetin (Tolectin); an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, Roxifen, or ketoprofen; an anticoagulant (blood thinner) such as warfarin (Coumadin); a steroid such as prednisone (Deltasone); insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others; probenecid (Benemid); lithium (Eskalith, Lithobid, others); or bismuth subsalicylate in drugs such as Pepto-Bismol. You may not be able to take Roxifen, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with Roxifen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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Dabroson Indication, Action Of Dabroson, Interactions, Dabroson

Dabroson [in more detail]

For the treatment of hyperuricemia associated with primary or secondary gout.

Dabroson Mechanism Of Action:

Dabroson inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the blood and urine. Dabroson also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, resulting in further reductions of serum uric acid concentrations.

Dabroson Drug Interactions:

Anisindione Dabroson increases the anticoagulant effect Azathioprine Dabroson increases the effect of thiopurine Cyclosporine Dabroson increases the effect and toxicity of cyclosporine Dicumarol Dabroson increases the anticoagulant effect Warfarin Dabroson increases the anticoagulant effect Mercaptopurine Dabroson increases the effect of thiopurine Acenocoumarol Increases the anticoagulant effect

Food Interactions:

Take with a full glass of water. Take with food. Avoid alcohol.

Dabroson Chemical Formula:

Euthycin, Euthycin

Synthroid is used for treating low thyroid hormone levels and certain types of goiters. It is also used with surgery and other medicines for managing certain types of thyroid cancer. Synthroid is a thyroid hormone. It works by replacing thyroid hormone when your body does not make enough on its own.

Use Synthroid as directed by your doctor.

Take Synthroid by mouth on an empty stomach at least one-half to one hour before breakfast.

Do not take an antacid or a product that has iron or calcium in it within 4 hours of taking Synthroid.

If the patient is a child or if you cannot swallow the tablet whole, you may crush the correct dose of the medicine. Add the crushed medicine to 1 to 2 teaspoons (5 to 10 mL) of water. Mix well. Use a spoon or dropper to give the medicine as soon as possible. Do not store the mixture for later use. Do not mix crushed tablets in soybean infant formula. Ask your pharmacist if you have any questions.

Synthroid works best if it is taken at the same time each day.

Continue to take Synthroid even if you feel well. Do not miss any dose.

It may take several weeks before you notice an improvement in your symptoms. Do not stop or change your dose of Synthroid without first checking with your doctor.

If you miss a dose of Synthroid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Synthroid.

Store Synthroid between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Protect from heat, light, and moisture. Do not store in the bathroom. Keep Synthroid out of the reach of children and away from pets.

Active Ingredient: Levothyroxine sodium.

Do NOT use Synthroid if:

you are allergic to any ingredient in Synthroid

you have untreated adrenal gland problems or high thyroid hormone levels

you have had a recent heart attack.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Synthroid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have trouble swallowing, heart or blood vessel problems (eg, coronary artery disease), high blood pressure, blood clotting or bleeding problems, pernicious anemia, diabetes, bone problems (eg, osteoporosis), fertility problems, pituitary problems, adrenal gland problems, or other thyroid problems

if you have problems absorbing nutrition from your stomach or intestines into your body

if you had a recent surgery or have an upcoming surgery.

Some medicines may interact with Synthroid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, nasal congestion, asthma, high blood pressure, irregular heartbeat or other heart problems, blood thinning, mental or mood problems, depression, diabetes, other thyroid problems, high cholesterol, hepatitis, weight loss, heartburn, birth control, hormone replacement therapy, growth hormone deficiency, cancer, seizures), and multivitamin products may interact with Synthroid, increasing the risk of side effects or decreasing effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Synthroid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

It is important to take Synthroid exactly as prescribed. Do not take more than the prescribed dose without checking with your doctor.

Tell your doctor or dentist that you take Synthroid before you receive any medical or dental care, emergency care, or surgery.

Diabetes patients - Synthroid may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Foods that contain soybean flour (including infant formula), cottonseed meal, walnuts, or dietary fiber may decrease the absorption of Synthroid. Tell your doctor if your diet includes any of these foods. Your doctor may need to change your dose of Synthroid.

Mild hair loss may rarely occur during the first few months of treatment with Synthroid. This is usually temporary. Contact your doctor if hair loss is severe or persistent.

Lab tests, including thyroid hormone level and growth checks, may be performed while you use Synthroid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Synthroid with caution in the elderly; they may be more sensitive to its effects, especially heart problems.

Children and teenagers may need regular growth checks while they take Synthroid.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. Your doctor may need to change your dose of Synthroid. Synthroid is found in breast milk. If you are or will be breast-feeding while you use Synthroid, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

No common side effects have been reported with the use of Synthroid.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; flushing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); changes in appetite; changes in menstrual periods; chest pain; diarrhea; excessive sweating; fast or irregular heartbeat; fever; heat intolerance; joint pain; leg cramps; mental or mood changes (eg, anxiety, irritability, nervousness); muscle weakness; seizures; severe or persistent headache or fatigue; shortness of breath; stomach cramps; tremors; trouble sleeping; unusual weight gain or weight loss; vomiting; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Synthroid is used for treating low thyroid hormone levels and certain types of goiters. It is also used with surgery and other medicines for managing certain types of thyroid cancer. Synthroid is a thyroid hormone. It works by replacing thyroid hormone when your body does not make enough on its own.

Use Synthroid as directed by your doctor.

Take Synthroid by mouth on an empty stomach at least one-half to one hour before breakfast.

Do not take an antacid or a product that has iron or calcium in it within 4 hours of taking Synthroid.

If the patient is a child or if you cannot swallow the tablet whole, you may crush the correct dose of the medicine. Add the crushed medicine to 1 to 2 teaspoons (5 to 10 mL) of water. Mix well. Use a spoon or dropper to give the medicine as soon as possible. Do not store the mixture for later use. Do not mix crushed tablets in soybean infant formula. Ask your pharmacist if you have any questions.

Synthroid works best if it is taken at the same time each day.

Continue to take Synthroid even if you feel well. Do not miss any dose.

It may take several weeks before you notice an improvement in your symptoms. Do not stop or change your dose of Synthroid without first checking with your doctor.

If you miss a dose of Synthroid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Synthroid.

Store Synthroid between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Protect from heat, light, and moisture. Do not store in the bathroom. Keep Synthroid out of the reach of children and away from pets.

Active Ingredient: Levothyroxine sodium.

Do NOT use Synthroid if:

you are allergic to any ingredient in Synthroid

you have untreated adrenal gland problems or high thyroid hormone levels

you have had a recent heart attack.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Synthroid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have trouble swallowing, heart or blood vessel problems (eg, coronary artery disease), high blood pressure, blood clotting or bleeding problems, pernicious anemia, diabetes, bone problems (eg, osteoporosis), fertility problems, pituitary problems, adrenal gland problems, or other thyroid problems

if you have problems absorbing nutrition from your stomach or intestines into your body

if you had a recent surgery or have an upcoming surgery.

Some medicines may interact with Synthroid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, nasal congestion, asthma, high blood pressure, irregular heartbeat or other heart problems, blood thinning, mental or mood problems, depression, diabetes, other thyroid problems, high cholesterol, hepatitis, weight loss, heartburn, birth control, hormone replacement therapy, growth hormone deficiency, cancer, seizures), and multivitamin products may interact with Synthroid, increasing the risk of side effects or decreasing effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Synthroid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

It is important to take Synthroid exactly as prescribed. Do not take more than the prescribed dose without checking with your doctor.

Tell your doctor or dentist that you take Synthroid before you receive any medical or dental care, emergency care, or surgery.

Diabetes patients - Synthroid may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Foods that contain soybean flour (including infant formula), cottonseed meal, walnuts, or dietary fiber may decrease the absorption of Synthroid. Tell your doctor if your diet includes any of these foods. Your doctor may need to change your dose of Synthroid.

Mild hair loss may rarely occur during the first few months of treatment with Synthroid. This is usually temporary. Contact your doctor if hair loss is severe or persistent.

Lab tests, including thyroid hormone level and growth checks, may be performed while you use Synthroid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Synthroid with caution in the elderly; they may be more sensitive to its effects, especially heart problems.

Children and teenagers may need regular growth checks while they take Synthroid.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. Your doctor may need to change your dose of Synthroid. Synthroid is found in breast milk. If you are or will be breast-feeding while you use Synthroid, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

No common side effects have been reported with the use of Synthroid.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; flushing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); changes in appetite; changes in menstrual periods; chest pain; diarrhea; excessive sweating; fast or irregular heartbeat; fever; heat intolerance; joint pain; leg cramps; mental or mood changes (eg, anxiety, irritability, nervousness); muscle weakness; seizures; severe or persistent headache or fatigue; shortness of breath; stomach cramps; tremors; trouble sleeping; unusual weight gain or weight loss; vomiting; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Synthroid is used for treating low thyroid hormone levels and certain types of goiters. It is also used with surgery and other medicines for managing certain types of thyroid cancer. Synthroid is a thyroid hormone. It works by replacing thyroid hormone when your body does not make enough on its own.

Use Synthroid as directed by your doctor.

Take Synthroid by mouth on an empty stomach at least one-half to one hour before breakfast.

Do not take an antacid or a product that has iron or calcium in it within 4 hours of taking Synthroid.

If the patient is a child or if you cannot swallow the tablet whole, you may crush the correct dose of the medicine. Add the crushed medicine to 1 to 2 teaspoons (5 to 10 mL) of water. Mix well. Use a spoon or dropper to give the medicine as soon as possible. Do not store the mixture for later use. Do not mix crushed tablets in soybean infant formula. Ask your pharmacist if you have any questions.

Synthroid works best if it is taken at the same time each day.

Continue to take Synthroid even if you feel well. Do not miss any dose.

It may take several weeks before you notice an improvement in your symptoms. Do not stop or change your dose of Synthroid without first checking with your doctor.

If you miss a dose of Synthroid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Synthroid.

Store Synthroid between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Protect from heat, light, and moisture. Do not store in the bathroom. Keep Synthroid out of the reach of children and away from pets.

Active Ingredient: Levothyroxine sodium.

Do NOT use Synthroid if:

you are allergic to any ingredient in Synthroid

you have untreated adrenal gland problems or high thyroid hormone levels

you have had a recent heart attack.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Synthroid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have trouble swallowing, heart or blood vessel problems (eg, coronary artery disease), high blood pressure, blood clotting or bleeding problems, pernicious anemia, diabetes, bone problems (eg, osteoporosis), fertility problems, pituitary problems, adrenal gland problems, or other thyroid problems

if you have problems absorbing nutrition from your stomach or intestines into your body

if you had a recent surgery or have an upcoming surgery.

Some medicines may interact with Synthroid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, nasal congestion, asthma, high blood pressure, irregular heartbeat or other heart problems, blood thinning, mental or mood problems, depression, diabetes, other thyroid problems, high cholesterol, hepatitis, weight loss, heartburn, birth control, hormone replacement therapy, growth hormone deficiency, cancer, seizures), and multivitamin products may interact with Synthroid, increasing the risk of side effects or decreasing effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Synthroid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

It is important to take Synthroid exactly as prescribed. Do not take more than the prescribed dose without checking with your doctor.

Tell your doctor or dentist that you take Synthroid before you receive any medical or dental care, emergency care, or surgery.

Diabetes patients - Synthroid may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Foods that contain soybean flour (including infant formula), cottonseed meal, walnuts, or dietary fiber may decrease the absorption of Synthroid. Tell your doctor if your diet includes any of these foods. Your doctor may need to change your dose of Synthroid.

Mild hair loss may rarely occur during the first few months of treatment with Synthroid. This is usually temporary. Contact your doctor if hair loss is severe or persistent.

Lab tests, including thyroid hormone level and growth checks, may be performed while you use Synthroid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Synthroid with caution in the elderly; they may be more sensitive to its effects, especially heart problems.

Children and teenagers may need regular growth checks while they take Synthroid.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. Your doctor may need to change your dose of Synthroid. Synthroid is found in breast milk. If you are or will be breast-feeding while you use Synthroid, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

No common side effects have been reported with the use of Synthroid.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; flushing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); changes in appetite; changes in menstrual periods; chest pain; diarrhea; excessive sweating; fast or irregular heartbeat; fever; heat intolerance; joint pain; leg cramps; mental or mood changes (eg, anxiety, irritability, nervousness); muscle weakness; seizures; severe or persistent headache or fatigue; shortness of breath; stomach cramps; tremors; trouble sleeping; unusual weight gain or weight loss; vomiting; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Glenmorangie Artein, Artein

Product Description

Glenmorangie Artein

The third release in its award winning Private Edition range. ‘Artein,’ Scots Gaelic for stone, is an intriguing marriage of 15 and 21 Years Old Glenmorangie, extra matured in ‘Super Tuscan’ wine casks.

Stone has always been at the heart of the making of Glenmorangie Single Malt Scotch Whisky. Glenmorangie has its own unique hard water source – the Tarlogie Spring – which slowly filters through layers of limestone, adding rich minerals that eventually give Glenmorangie its complex fruity aromas. Stone also plays a more symbolic role for Glenmorangie. Located on grounds near the Glenmorangie distillery is the Hilton of Cadbol Stone, an 8th century Pictish artifact, rich in ancient intricate carvings. This treasure became the inspiration for Glenmorangie’s iconic emblem, The Signet.

Dr. Bill Lumsden, Glenmorangie’s Head of Distilling & Whisky Creation, is renowned for pioneering the innovative approach of extra maturing whisky in ex-wine casks. He has long felt a strong affinity with the innovative ‘Super Tuscan’ wine producers who are justly celebrated for breaking with established Italian wine making traditions. The rugged Tuscan coastal hills, located on stony ground, seem an improbable area for establishing vineyards, yet the stone plays an important role in the taste of these special wines. The vines are forced to take root deep into the soil for nourishment and as a result the grapes ripen with the intense flavor of this unique terrain.

Dr. Lumsden comments, “Wine is one of my huge passions and I was fascinated by the role the stony ground played in the flavor profile of the famous ‘Super-Tuscan’ wines. I was inspired to experiment with extra maturing Glenmorangie in these wine casks and was thrilled with the result: a rich, outstandingly fragrant whisky — quite literally born of stone.”

Glenmorangie Artein’s recipe has two thirds hand selected 15 year old whisky with a special additional one third of 21 year old whisky. The spirit started its maturation in American white oak ex-bourbon casks before individually spending a period of extra maturation in Super Tuscan wine casks. On the nose, Glenmorangie Artein recalls a sweet and heady bouquet of ripe red berries, honeysuckle and fresh mint. On the palate, one can taste sun-soaked baked fruits such as ripe apricots, peaches and plums which harmonize fluidly with hints of spearmint and cherries in milk chocolate. A whisky of great length, bottled at a strength of 46% alcohol by volume, Glenmorangie Artein finishes with high notes of zesty, lemon sherbet and a flourish of creamy cappuccino.

Glenmorangie Artein is the latest addition to the ongoing Private Edition range, which consists of rare and interesting limited edition whiskies selected from “the cabinet of curiosities” of Dr. Bill Lumsden. Released on an annual basis, this range comprises the highly esteemed Sonnalta PX and Finealta. Brian Cox, Vice President Glenmorangie in the U. S. commented, “These Private Editions are fast becoming valued collector’s items. We have completely sold out of the last two Editions and anticipate that Glenmorangie Artein 15 Years Old will sell out even faster since the Super Tuscan casks make this a very rare Private Edition indeed.” Artein is available in the U. S. from February 1st, 2012.

About Glenmorangie: Glenmorangie Single Malt Scotch Whisky originates in the Scottish Highlands where, at the Glenmorangie Distillery, it is distilled in the tallest malt whisky stills in Scotland, expertly matured in the finest oak casks, and perfected by the Men of Tain. The Distillery was founded in 1843 and is renowned as a pioneer in its field uniting tradition with innovation to create ‘unnecessarily well made whiskies.’

About The Glenmorangie Company The Company is one of the most renowned and innovative distillers of Scotch whisky brands worldwide and is part of Moët Hennessy, the wine and spirits division of Moët Hennessy Louis Vuitton ( LVMH ). Headquartered in Edinburgh, Scotland, the company produces two main single malt brands – Glenmorangie Single Highland Malt Scotch Whisky and Ardbeg Single Islay Malt Whisky.

The Glenmorangie Private Edition Range Glenmorangie’s Private Edition is an award winning special range that provides the occasional opportunity for the Glenmorangie Whisky Creation Team to share rare, limited samples of its rich and innovative experimentations to whisky connoisseurs and aficionados. Glenmorangie Artein marks the third release in this range; previous releases were Glenmorangie Sonnalta PX – a full bodied whisky, extra matured in Pedro Ximénez sherry casks and Glenmorangie Finealta – an exquisite recreation of a 1900s recipe from the Glenmorangie archives with subtle notes of peat.

Climesse 2 Mg, Merigest

4.1 Therapeutic indications

Hormone replacement therapy (HRT) for oestrogen deficiency symptoms in postmenopausal women.

Prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis.

(See also section 4.4.)

The experience treating women older than 65 years is limited.

4.2 Posology and method of administration

Climesse is a continuous combined hormone replacement therapy.

One tablet to be taken daily, as directed on the 28 day calendar pack. Climesse should be taken continuously without a break between packs.

It is recommended that Climesse should not be taken by women until at least 12 months after their last natural menstrual bleed. Irregular bleeding during tablet taking may occur during the first few months of therapy but is usually transient, and amenorrhoea will develop in a majority of women. Amenorrhoea is most likely to occur in women who are more than 2 years post-menopausal but may also be achieved before that in a significant proportion of women. After 3-4 months treatment, some women may experience continued unacceptable bleeding and in these cases Climesse should be discontinued. If bleeding subsides within three weeks then no further investigation is needed.

Pregnancy should be excluded before starting therapy.

For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration (see also section 4.4) should be used.

Unless there is a previous diagnosis of endometriosis, it is not recommended to add a progestagen in hysterectomised women.

Patients changing from another continuous sequential or cyclical preparation should complete the cycle and may then change to Climesse without a break in therapy. Patients changing from a continuous combined preparation may start therapy at any time if amenorrhoea is established, or otherwise start on the first day of bleeding.

Climesse should normally be used only in women more than 12 months postmenopausal. When changing from sequential therapy menopausal status may not be known, and in some women endogenous oestrogens may still be being produced. This could result in unpredictable bleeding patterns.

If a tablet is missed, it should be taken within 12 hours of when normally taken; otherwise the tablet should be discarded, and the usual tablet should be taken the following day. Forgetting or missing a dose may increase the likelihood of breakthrough bleeding.

Use in the elderly

Climesse should only be used in the elderly for the indications listed.

Use in children

Climesse should not be used in children

• Known, past or suspected breast cancer,

• Known or suspected oestrogen-dependent malignant tumours (e. g. endometrial cancer),

• Undiagnosed genital bleeding,

• Untreated endometrial hyperplasia,

• Severe renal disease,

• Previous or current venous thromboembolism (deep venous thrombosis, pulmonary embolism),

• Known thrombophilic disorders (e. g. protein C, protein S, or antithrombin deficiency, see section 4.4),

• Active or recent arterial thromboembolic disease (e. g. angina, myocardial infarction),

• Acute liver disease, or a history of liver disease as long as liver function tests have failed to return to normal,

• Known hypersensitivity to the active substances or to any of the excipients listed in section 6.1,

4.4 Special warnings and precautions for use

For the treatment of postmenopausal symptoms, HRT should only be initiated for symptoms that adversely affect quality of life. In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually and HRT should only be continued as long as the benefit outweighs the risk.

Evidence regarding the risks associated with HRT in the treatment of premature menopause is limited. Due to the low level of absolute risk in younger women, however, the balance of benefits and risks for these women may be more favourable than in older women.

Before initiating or reinstituting HRT, a complete personal and family medical history should be taken. Physical (including pelvic and breast) examination should be guided by this and by contraindications and warnings for use.

During treatment, periodic check-ups are recommended of a frequency and nature adapted to the individual woman. Women should be advised what changes in their breasts should be reported to their doctor or nurse (see 'Breast cancer' below). Investigations, including appropriate imaging tools, e. g. mammography, should be carried out in accordance with currently accepted screening practices, modified to the clinical needs of the individual.

Conditions which need supervision

If any of the following conditions are present, have occurred previously, and/or have been aggravated during pregnancy or previous hormone treatment, the patient should be closely supervised. It should be taken into account that these conditions may recur or be aggravated during treatment with Climesse, in particular:

− leiomyoma (uterine fibroids) or endometriosis,

− risk factors for thromboembolic disorders (see below),

− risk factors for oestrogen dependent tumours, e. g. 1 st degree heredity for breast cancer,

− liver disorders (e. g. liver adenoma),

− diabetes mellitus with or without vascular involvement,

− migraine or (severe) headache,

− systemic lupus erythematosus (SLE),

− a history of endometrial hyperplasia (see below),

Reasons for immediate withdrawal of therapy:

Therapy should be discontinued in case a contra-indication is discovered and in the following situations:

− jaundice or deterioration in liver function,

− significant increase in blood pressure,

− new onset of migraine-type headache,

Endometrial hyperplasia and carcinoma

In women with an intact uterus the risk of endometrial hyperplasia and carcinoma is increased when oestrogens are administered alone for prolonged periods. The reported increase in endometrial cancer risk among oestrogen-only users varies from 2-to 12-fold greater compared with non-users, depending on the duration of treatment and oestrogen dose (see section 4.8). After stopping treatment risk may remain elevated for at least 10 years. The addition of a progestagen cyclically for at least 12 days per month/28 day cycle or continuous combined oestrogen-progestagen therapy in non-hysterectomised women prevents the excess risk associated with oestrogen-only HRT.

Break-through bleeding and spotting may occur during the first months of treatment. If break-through bleeding or spotting appears after some time on therapy, or continues after treatment has been discontinued, the reason should be investigated, which may include endometrial biopsy to exclude endometrial malignancy.

The overall evidence suggests an increased risk of breast cancer in women taking combined oestrogen-progestagen and possibly also oestrogen-only HRT, that is dependent on the duration of taking HRT.

Combined oestrogen-progestagen therapy

The randomised placebo-controlled trial, the Women's Health Initiative study (WHI), and epidemiological studies are consistent in finding an increased risk of breast cancer in women taking combined oestrogen-progestagen for HRT that becomes apparent after about 3 years (see section 4.8).

The WHI trial found no increase in the risk of breast cancer in hysterectomised women using oestrogen-only HRT. Observational studies have mostly reported a small increase in risk of having breast cancer diagnosed that is substantially lower than that found in users of oestrogen-progestagen combinations (see section 4.8).

The excess risk becomes apparent within a few years of use but returns to baseline within a few (at most five) years after stopping treatment.

HRT, especially oestrogen-progestagen combined treatment, increases the density of mammographic images which may adversely affect the radiological detection of breast cancer.

HRT is associated with a 1.3 - to 3 - fold risk of developing venous thromboembolism (VTE), i. e. deep vein thrombosis or pulmonary embolism. The occurrence of such an event is more likely in the first year of HRT than later (see Section 4.8).

Generally recognised risk factors for VTE include use of oestrogens, older age, major surgery, prolonged immobilisation, obesity (Body Mass Index > 30kg/m²), pregnancy/ postpartum period, and systemic lupus erythematosus (SLE) and cancer.

There is no consensus about the possible role of varicose veins in VTE.

Patients with known thrombophilic states have an increased risk of VTE and HRT may add to this risk. HRT is therefore contraindicated in these patients (see section 4.3). Women already on chronic anticoagulant treatment require careful consideration of the benefit-risk of use of HRT.

As in all post-operative patients, prophylactic measures need to be considered to prevent VTE following surgery. If prolonged immobilisation is to follow elective surgery, temporarily stopping HRT four to six weeks earlier is recommended. Treatment should not be restarted until the woman is completely mobilised.

In women with no personal history of VTE but with a first degree relative with a history of thrombosis at young age, screening may be offered after careful counselling regarding its limitations (only a proportion of thrombophilic defects are identified by screening). If a thrombophilic defect is identified which segregates with thrombosis in family members or if the defect is 'severe' (e. g, antithrombin, protein S, or protein C deficiencies or a combination of defects) HRT is contraindicated.

If VTE develops after initiating therapy, the drug should be discontinued. Patients should be told to contact their doctors immediately when they are aware of a potential thromboembolic symptom (e. g. painful swelling of a leg, sudden pain in the chest, dyspnoea).

Coronary artery disease (CAD)

There is no evidence from randomised controlled trials of protection against myocardial infarction in women with or without existing CAD who received combined oestrogen-progestagen or oestrogen-only HRT.

Combined oestrogen-progestagen therapy

The relative risk of CAD during use of combined oestrogen-progestagen HRT is slightly increased. As the baseline absolute risk of CAD is strongly dependent on age, the number of extra cases of CAD due to oestrogen-progestagen use is very low in healthy women close to menopause, but will rise with more advanced age.

Randomised controlled data found no increased risk of CAD in hysterectomised women using oestrogen-only therapy.

Combined oestrogen-progestagen and oestrogen-only therapy are associated with an up to 1.5-fold increase in risk of ischaemic stroke. The relative risk does not change with age or time since menopause. However, as the baseline risk of stroke is strongly age-dependent, the overall risk of stroke in women who use HRT will increase with age (see section 4.8).

Ovarian cancer is much rarer than breast cancer. Long-term (at least 5 to 10 years) use of oestrogen-only HRT products has been associated with a slightly increased risk of ovarian cancer (see section 4.8).

Some studies including the WHI trial suggest that the long-term use of combined HRTs may confer a similar, or slightly smaller, risk (see Section 4.8).

Oestrogens may cause fluid retention, and therefore patients with cardiac or renal dysfunction should be carefully observed.

Women with pre-existing hypertriglyceridemia should be followed closely during oestrogen replacement or hormone replacement therapy, since rare cases of large increases of plasma triglycerides leading to pancreatitis have been reported with oestrogen therapy in this condition.

Oestrogens increase thyroid binding globulin (TBG), leading to increased circulating total thyroid hormone, as measured by protein-bound iodine (PBI), T4 levels (by column or by radio-immunoassay) or T3 levels (by radio-immunoassay). T3 resin uptake is decreased, reflecting the elevated TBG. Free T4 and free T3 concentrations are unaltered. Other binding proteins may be elevated in serum, i. e. corticoid binding globulin (CBG), sex-hormone-binding globulin (SHBG) leading to increased circulating corticosteroids and sex steroids, respectively.

Free or biological active hormone concentrations are unchanged. Other plasma proteins may be increased (angiotensinogen/renin substrate, alpha-I-antitrypsin, ceruloplasmin).

Thyroid function should be monitored regularly in patients who require thyroid hormone replacement therapy and who are also taking oestrogen in order to ensure that thyroid hormone levels remain within an acceptable range.

HRT use does not improve cognitive function. There is some evidence of increased risk of probable dementia in women who start using continuous combined or oestrogen-only HRT after the age of 65.

Oestrogens may induce or exacerbate symptoms of angioedema, in particular in women with hereditary angioedema.

Patients with rare hereditary problems of galactose intolerance, of Lapp lactase deficiency or of glucose-galactose malabsorption should not take this medicine.

4.5 Interaction with other medicinal products and other forms of interaction

The metabolism of oestrogens and progestagens may be increased by concomitant use of substances known to induce drug-metabolising enzymes, specifically cytochrome P450 enzymes, such as anticonvulsants (e. g. phenobarbital, phenytoin, carbamazepine) and anti-infectives (e. g. rifampicin, rifabutin, nevirapine, efavirenz).

Ritonavir, telaprevir and nelfinavir, although known as strong inhibitors, by contrast exhibit inducing properties when used concomitantly with steroid hormones.

Herbal preparations containing St John's wort ( Hypericum perforatum ) may induce the metabolism of oestrogens and progestagens.

Clinically, an increased metabolism of oestrogens and progestagens may lead to decreased effect and changes in the uterine bleeding profile.

Some laboratory tests may be influenced by oestrogen therapy, such as tests for glucose tolerance or thyroid function.

4.6 Pregnancy and lactation

Climesse is not indicated during pregnancy. If pregnancy occurs during medication with Climesse, treatment should be withdrawn immediately.

Data on a limited number of exposed pregnancies indicate adverse effects of norethisterone on the foetus. At doses higher than normally used in OC and HRT formulations, masculinisation of the female foetus was observed.

The results of most epidemiological studies to date relevant to inadvertent foetal exposure to combinations of oestrogens and progestagens indicate no teratogenic or foetotoxic effects.

Climesse is not indicated during lactation.

4.7 Effects on ability to drive and use machines

No adverse effects on the ability to drive or operate machines have been recorded.

4.8 Undesirable effects

Table 1 represents adverse drug reactions from legacy clinical trials combined with adverse drug reactions from post-marketing experience. The adverse drug reactions are listed according to the system organ class in MedDRA and the frequency is not known.

Table 1 Adverse drug reactions

Neoplasms benign, malignant and unspecified (including cysts and polyps)

Breast cancer risk

- An up to 2-fold increased risk of having breast cancer diagnosed is reported in women taking combined oestrogen-progestagen therapy for more than 5 years,

- Any increased risk in users of oestrogen-only therapy is substantially lower than that seen in users of oestrogen-progestagen combinations,

- The level of risk is dependent on the duration of use (see section 4.4),

- Results of the largest randomised placebo-controlled trial (WHI-study) and largest epidemiological study (MWS) are presented.

Million Women study– Estimated additional risk of breast cancer after 5 years' use

Age range (years)

Additional cases per 1000 never-users of HRT over a 5 year period*

‡When the analysis was restricted to women who had not used HRT prior to the study there was no increased risk apparent during the first 5 years of treatment: after 5 years the risk was higher than in non-users.

* WHI study in women with no uterus, which did not show an increase in risk of breast cancer.

Endometrial cancer risk

Postmenopausal women with a uterus

The endometrial cancer risk is about 5 in every 1000 women with a uterus not using HRT.

In women with a uterus, use of oestrogen-only HRT is not recommended because it increases the risk of endometrial cancer (see section 4.4).

Depending on the duration of oestrogen-only use and oestrogen dose, the increase in risk of endometrial cancer in epidemiology studies varied from between 5 and 55 extra cases diagnosed in every 1000 women between the ages of 50 and 65.

Adding a progestagen to oestrogen-only therapy for at least 12 days per cycle can prevent this increased risk. In the Million Women Study the use of five years of combined (sequential or continuous) HRT did not increase risk of endometrial cancer (RR of 1.0 (0.8-1.2)).

Long-term use of oestrogen-only and combined oestrogen-progestagen HRT has been associated with a slightly increased risk of ovarian cancer. In the Million Women Study 5 years of HRT resulted in 1 extra case per 2500 users.

Risk of venous thromboembolism

HRT is associated with a 1.3 - to 3-fold increased relative risk of developing venous thromboembolism (VTE), i. e. deep vein thrombosis or pulmonary embolism. The occurrence of such an event is more likely in the first year of using HRT (see section 4.4). Results of the WHI studies are presented:

WHI Studies - Additional risk of VTE over 5 years' use

Age range (years)

Incidence per 1000 women in placebo arm over 5 years

* Study in women with no uterus.

Risk of coronary artery disease

- The risk of coronary artery disease is slightly increased in users of combined oestrogen-progestagen HRT over the age of 60 (see section 4.4).

Risk of ischaemic stroke

- The use of oestrogen-only and oestrogen-progestagen therapy is associated with an up to 1.5 - fold increased relative risk of ischaemic stroke. The risk of haemorrhagic stroke is not increased during use of HRT,

- This relative risk is not dependent on age or on duration of use, but as the baseline risk is strongly age-dependent, the overall risk of stroke in women who use HRT will increase with age, see section 4.4.

WHI studies combined - Additional risk of ischaemic stroke* over 5 years' use

Age range (years)

Incidence per 1000 women in placebo arm over 5 years

Risk ratio and 95%CI

Additional cases per 1000 HRT users over 5 years

* No differentiation was made between ischaemic and haemorrhagic stroke.

Other adverse reactions have been reported in association with oestrogen/progestagen treatment:

- gall bladder disease,

- skin and subcutaneous disorders: chloasma, erythema multiforme, erythema nodosum, vascular purpura,

- probable dementia over the age of 65 (see section 4.4),

- tear film composition changes.

No reports of adverse effects from overdosage have been reported. There are no specific antidotes for overdosage and if further treatment is required it should be symptomatic.

5. Pharmacological properties

5.1 Pharmacodynamic properties

Pharmacotherapeutic group: progestagens and oestrogens, ATC code: G03F A01.

The active ingredient, synthetic 17β-estradiol, is chemically and biologically identical to endogenous human oestradiol. It substitutes for the loss of oestrogen production in menopausal women, and alleviates menopausal symptoms. Oestrogens prevent bone loss following menopause or ovariectomy.

Oestradiol valerate is used in oestrogen deficient states. Treatment with oestrogens relieves menopausal vasomotor symptoms. Oestrogens cross the placenta.

As oestrogens promote the growth of the endometrium, unopposed oestrogens increase the risk of endometrial hyperplasia and cancer. The addition of progestagen greatly reduces the oestrogen induced risk of endometrial hyperplasia in non-hysterectomised women.

Norethisterone is a progestagen added to prevent endometrial hyperplasia and increased risk of endometrial carcinoma which can be induced by unopposed oestrogen use.

Prevention of osteoporosis

Oestrogen deficiency at menopause is associated with an increasing bone turnover and decline in bone mass. The effect of oestrogens on the bone mineral density is dose-dependent. Protection appears to be effective for as long as treatment is continued. After discontinuation of HRT, bone mass is lost at a rate similar to that in untreated women.

Evidence from the WHI trial and meta-analysed trials shows that current use of HRT, alone or in combination with a progestagen – given to predominantly healthy women - reduces the risk of hip, vertebral, and other osteoporotic fractures. HRT may also prevent fractures in women with low bone density and/or established osteoporosis, but the evidence for that is limited.

5.2 Pharmacokinetic properties

Oestradiol valerate, like most natural oestrogens, is readily and fully absorbed from the gastrointestinal (GI) tract. When given orally in doses of 1 to 2 mg, peak plasma concentrations of oestradiol are generally observed 3 to 6 hours post dose. Oestradiol is also known to undergo enterohepatic re-circulation.

In the systemic circulation, oestradiol is approximately 52% bound to plasma albumin and 45-46% to sex hormone binding globulin. Only 2% is free and biologically active.

Oestradiol undergoes extensive first-pass metabolism. Oestradiol is metabolised primarily in the liver to oestrone, then later to oestriol, epioestriol and catechol oestrogens, which are then conjugated to sulphates and glucuronides. Cytochrome 450 isoforms CYP1A2 and CYP3A4 catalyse the hydroxylation of oestradiol, forming oestriol. Oestriol is glucuronidated by UGT1A1 and UGT2B7 in humans. Oestradiol metabolites are subject to enterohepatic circulation. Other metabolites (e. g. 2-methoxy, 2-hydroxy-3-methoxy and 4-methoxy estradiol) have been identified.

The elimination half life of oestradiol is approximately 1 hour. Systemic concentrations of oestradiol returned to baseline (e. g. pre-treatment concentrations) in 24 hours (range 6 to 48 hours) post dose. Oestradiol is excreted via the kidney in the urine as sulphate and glucuronide esters, while a small proportion is excreted as unchanged oestradiol.

Norethisterone is absorbed from the GI tract and its effects last for at least 24 hours. When a dose of 1 mg is given, there are wide variations in serum norethisterone levels at any particular time point after dosing (100 to 1700 pg/mL). Norethisterone undergoes first pass effect with a resulting loss of 36% of the dose. When injected, it is detectable in the plasma after 2 days and is not completely excreted in the urine after 5 days. There are large inter-subject variations in bioavailability.

In plasma, norethindrone is bound approximately 35% to sex hormone-binding globulin (SHBG) and 61% to albumin. Only 4% is free and biologically active.

The most important metabolites are several isomers of 5 alpha-dihydronorethisterone and tetrahydronorethisterone which are further metabolised to glucuronides.

The elimination half-life of norethisterone is reported to be 6 to 8 hours, and is eliminated primarily in urine as glucuronides of metabolites. There are large inter-subject variations in elimination half-life.

5.3 Preclinical safety data

Acute toxicity of oestrogens is low. Because of marked differences between animal species and between animals and humans, preclinical results possess a limited predictive value for the application of oestrogens in humans.

In experimental animals oestradiol or oestradiol valerate displayed an embryolethal effect at relatively low oral doses; malformations of the urogenital tract and feminisation of male foetuses were observed.

Norethisterone, like other progestagens, caused virilisation of female fetuses in rats and monkeys. After high oral doses of norethisterone, embryolethal effects were observed.

Long-term, continuous administration of natural and synthetic oestrogens and norethisterone in some animal species increases the frequency of tumours in certain hormone dependent tissues.

6. Pharmaceutical particulars

6.1 List of excipients

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Glucored Forte, Glucored Forte

Glucored Forte

Mechanism of action of Glibenclamide :

This Medication Contains Sulfonylurea And Biguanide Antidiabetic Combination, Prescribed For Type 2 Diabetes.

Drug Interaction of Glibenclamide :

Before Using This Medication, Tell Your Doctor Or Pharmacist Of All Prescription And Non-prescription/herbal Products You May Use, Especially Of:Medications For High Blood Pressure Such As ACE Inhibitors E. g. Captopril. Beta-blockers E. g. Propranolol (including Eye Drops). Bosentan. Diazoxide. Fluvastatin, Medications To Treat Infections Such As - Chloramphenicol. Ciprofloxacin. Fluconazole (fungal Infections). Miconazole (fungal Infections). Norfloxacin. Rifampicin (for Tuberculosis). Voriconazole (fungal Infections), Coumarins (to Stop Blood Clotting) Such As Warfarin Some Types Of Painkiller Known As Non-steroidal Anti-inflammatory Drugs (NSAIDs) Such As Aspirin Sulfinpyrazone (for Gout), Topiramate (for Epilepsy), Cimetidine (for Ulcers And Indigestion, Fibrates (for High Cholesterol) Such As Clofibrate, Lanreotide (for Hormone Producing Tumours) Monoamine Oxidase Inhibitors (MAOIs; For Depression Such As Moclobemide And Phenelzine, Octreotide (for Hormone Producing Tumours), Phenothiazines (some Anti-psychotics To Treat Psychoses Such Asschizophrenia And Some Antihistamines To Treat Allergies), Anabolic Steroids Such As Testosterone, Corticosteroids Such As Hydrocortisone, Diuretics (increases Urine Output), Such As Thiazide Diuretics E. g.bendroflumethiazide, Oestrogens, Progestogens (e. g. Oral Contraceptives)

Side effects of Glibenclamide :

Nausea And Stomach Upset

INTERACTIONS OF GLIBENCLAMIDE

Metformin Is Used In The Treatment Of Diabetes Mellitus, Insulin Resistance, And Obesity.

Mechanism of action of Metformin :

The Exact Mechanism Of Action Of Metformin Is Not Clear But It Appears To Act By Decreasing Glucose Absorption From The Intestine, Decreasing Production Of Glucose From Proteins And Fats In Liver, And Enhancing Insulin Sensitivity In Muscle By Increasing Glucose Uptake And Utilization.

Drug Interaction of Metformin :

Taking Metformin With Other Anti-diabetic Drugs May Lead To Excessive Lowering Of Bloodsugar. If You Go For An X-ray Or Scan, Do Not Take Metformin Before And At Least 48 Hours Afterwards. Metformin With Diuretics (furosemide), Anti-asthmatic Drugs Such As Salbutamol Or Terbutaline, Or Corticosteroids (prednisone) May Affect The Glucose Control. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required.

Side effects of Metformin :

The Common Side Effects Are Urge To Vomit, Vomiting, Diarrhea, Abdominal Pain, Loss Of Appetite, Malabsorption Of Vitamin B12, Taste Disturbance, And Altered Liver Functions. Also, The Patient May Have The Side Effects Of Lactic Acidosis (symptoms Are Vomiting, Abdominal Pain With Muscle Cramps, Not Feeling Well With Severe Tiredness, And Difficulty In Breathing), And Skin Reactions Such As Redness Of Skin, Itching, Hives (pale Red, Raised, Itchy Bumps Of Skin).

INTERACTIONS OF METFORMIN

How Metformin will impact on Pregnancy ?

Information Not Available.

Steuben Glass Varieties And Patterns, Aurene

Steuben Glass Varieties and Patterns

By Pamela Wiggins. Antiques Expert

Pamela Y. Wiggins practically grew up in her mother's antique shop where she learned the ins and outs of the business, lots of background on interesting old objects, and numerous tactics for savvy collecting. She continued on as an adult collector and expanded her study as a journalist specializing in antiques and collectibles.

Like ABOUT ANTIQUES WITH PAMELA WIGGINS on Facebook.

Updated April 10, 2016.

Steuben Glass Works made a wide variety of glass during its years in production. From those with an iridescent finish to pieces filled with decorative bubbles, learn about a number of them here.

1. Aurene

Steuben Blue Aurene Vase. - Photo Courtesy of Morphy Auctions

The first Gold Aurene glass was made by Steuben in 1904, and it was eventually produced in blue (as shown here), brown, red and green. The name of that first glass referred to the golden iridescence of the finish.

The base glass used for these pieces was usually clear, amber or topaz. Tin and iron chloride sprays were used to give them their matte finish, according to The Collector’s Encyclopedia of American Art Glass by John A. Shuman III.

When examined with magnification, thousands of tiny fractures can be seen in the surface of Aurene glass, which both reflect and refract light to give it the finish its sheen. If spots were missed when the spray was being applied, the resulting mirror gloss was considered undesirable.

Blue Aurene came about in 1905 when cobalt was added to the Gold Aurene formula. Brown Aurene was made using brown glass sprayed with tin chloride. Alabaster and Calcite Steuben pieces were used as the base for Red and Green Aurene finishes decorated with flowers, leaf shapes, and a decorative technique known as feathering or trailing threads.

Aurene was a Steuben staple until 1933 when production of these wares ceased. Vases were made more often than any other type of Aurene finished glass. All colors are considered to be rare and desirable collectibles, although Gold Aurene and Blue Aurene tend to be found most often. The marks frequently used on these pieces were "AURENE" and "STEUBEN AURENE" written in a rather amateurish fashion.

When new, Aurene glass competed with glassware made by both Loetz in Austria and Tiffany in the United States. After first seeing Aurene glass, Louis Comfort Tiffany sued Steuben thinking his Favrile glass was being copied. When, in fact, the method used to make Steuben's version was actually very different than Tiffany’s process for imparting an iridescent finish. The suit reportedly never made it to court.

About the Piece Shown Here:

This Blue Aurene vase measuring 7 1/2" tall is referenced as shape #2683. It features a nice, even iridescence prized by collectors and is in excellent condition overall. Unmarked with only polished pontil on the bottom (so it was likely marked with a paper label when new in the early 1900s). This piece sold for $720 (not including buyer's premium) at Morphy Auctions in February, 2013.

Continue Reading Below

2. Bubbly

Steuben Bubbly Glassware with Green Threading. - Photo Courtesy of Morphy Auctions

While certainly not the only manufacturer to make this type of glass, Steuben's wares of this sort certainly have their fans in collecting circles. Frederick Carder, co-founder of Steuben Glass Works, developed this "air trap" style of glass known as Bubbly in the 1920s and it was made by the firm into the 1930s. He may have been inspired by his prior work with Emile Galle. who also artfully used air bubbles to decorate glass.

The first pieces of Steuben's Bubbly were made using spiked molds. "When molten glass was rolled over the slab, the spikes left marks in the hot glass. A second applied layer of glass locked in the air, so that the controlled designs could be achieved," according to The Collector’s Encyclopedia of American Art Glass by John A. Shuman III. The result was a fairly consistent pattern of bubbles throughout the glass.

Random air bubbles in some Bubbly pieces were created by introducing a willow branch into the glass while hot and removing it immediately. Gasses released from the green wood would enable the glass artisans to work the bubbles. This method also eliminated green and pink tinges that might occur in colorless glass, according to Shuman.

All the objects commonly made by Steuben were fashioned of this type of glass, including vases, bowls, perfume bottles, and candlesticks. Colors used were clear, Antique Green, Bristol Yellow, Wisteria, Topaz, French Blue, and Pomona Green.

Some pieces also had a threading design added for interest. The threading could be in the same color as the base piece, or in a contrasting color like the green threading on clear glass shown here.

Not all Bubbly pieces are found marked. Some have etched markings on the bottoms, while others have paper labels still attached. Some of those have the pattern name written in the center of the sticker.

About the Pieces Shown Here:

This lot of Steuben Bubbly pieces included matching candlesticks, and two different vase styles. Two of the pieces were etched with Steuben marks on their bases. All four pieces have contrasting threading decor in green. The lot sold for $287.50 (not including buyer’s premium) at Morphy Auctions in December, 2010.

3. Threading and Reeding

Steuben Glassware Decorated with Threading and Reeding. - Photo Courtesy of Morphy Auctions

This method of decorating many pieces made by Steuben Glass Works involved applying threads of glass to the outer surfaces of completed wares. Some pieces, as with the bowl shown above, were decorated over the entire body. Most pieces, however, were only decorated on a portion of the object.

“When the spirals are fairly regular and close together, the decor was accomplished by machine and is correctly termed ‘threaded’ decoration.

On objects where the application is both irregular and haphazard, we say that the piece possesses a ‘reeded decoration’,” according to Shuman.

Most of this type of decoration was applied to a clear or iridescent blown glass base piece whether threaded or reeded. Hand applied reeding can measure from very fine hair-like strands to fairly thick measuring up to 1/4-inch wide. The technique was achieved by the glassmaker rotating an object attached to a pontil rod over the arms of a chair. Molten glass threads were then poured onto the piece in a careful application. Some pieces have a vertical application of the threads so that they run up down in an overlapping fashion, according to Shuman. Some threads were marvered, or made flush with the surface, while others remained raised above of the base glass.

Threading that was not marvered into the base glass is more subject to damage since it can break off rather easily. In fact, it’s always wise to check Steuben threaded or reeded pieces for flaws before purchasing them. The texture on this type of glass is also known for harboring dust and dirt within the intricate pattern of the threads.

About the Pieces Shown Here:

All the pieces shown are clear glass with green threading or reeding. This includes five wine glasses, a toothpick holder, two candlesticks, and three vases with the largest being 10” tall and all in excellent condition. These pieces sold as a lot for $316.25 (not including buyer’s premium) at Morphy Auctions in December, 2010.

Continue Reading Below

4. Verre de Soie

Steuben Verre de Soie White Silk Glass Vase and Pinched Edge Bowl. - Photo Courtesy of Morphy Auctions

Verre de Soie . pronounced "v-air da swah", was made by Steuben Glass Works while Frederick Carder was art director for the firm from 1903 to 1933. The name actually translates to "silk glass" in French.

This type of finish was previously known as “Flint Iridescent” when it was made as early as the mid-1880s by Stevens and Williams, an English glass company Carder worked for prior to co-founding Steuben, according to Shuman.

Referred to as "V. D.S." by Steuben’s employees, this type of frosty hue was achieved by spraying stannous chloride on a base piece crafted of clear glass. The result was a white surface with a very silky feel. And while it is hard to photograph, the finish also casts a faint rainbow spectrum that was as popular with consumers when it was new as it is with collectors today. It was also Carder's favorite iridescent glass back in the day.

Consumers and collectors have referred to it as "Glass of Silk", "Angel’s Breath" and "Angel Skin" from time to time as well.

Dimenhydrinate - Fda Prescribing Information, Side Effects And Uses, Dimenhidrinato

Dimenhydrinate

Dimenhydrinate, an anti-nauseant/antiemetic, is the 8-chlorotheophylline salt of diphenhydramine. It contains not less than 53% and not more than 55.5% of diphenhydramine, and not less than 44% and not more than 47% of 8-chlorotheophylline, calculated on the dried basis. Chemically, it is 8-chlorotheophylline compound with 2(diphenylmethoxy)-N, N-dimethylethylamine (1:1), and the structural formula is:

C 17 H 21 NO•C 7 H 7 ClN 4 O 2 M. W. 469.96

Dimenhydrinate Injection, USP contains a sterile solution of Dimenhydrinate 50 mg/mL; Propylene Glycol 50%; Benzyl Alcohol 5% as preservative; and Water for Injection q. s. Sodium Hydroxide and/or Hydrochloric Acid may have been used to adjust pH.

Dimenhydrinate - Clinical Pharmacology

While the precise mode of action of Dimenhydrinate is not known, it has a depressant action on hyperstimulated labyrinthine function.

Indications and Usage for Dimenhydrinate

Dimenhydrinate Injection, USP is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.

Contraindications

Neonates and patients with a history of hypersensitivity to Dimenhydrinate or its components (diphenhydramine or 8-chlorotheophylline) should not be treated with Dimenhydrinate.

Note: This product contains Benzyl Alcohol. Benzyl Alcohol has been associated with a fatal “Gasping Syndrome” in premature infants and infants of low birth weight.

Warnings

Caution should be used when Dimenhydrinate is given in conjunction with certain antibiotics that may cause ototoxicity, since Dimenhydrinate is capable of masking ototoxic symptoms, and an irreversible state may be reached.

This drug may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. The concomitant use of alcohol or other central nervous system depressants may have an additive effect. Therefore, patients should be warned accordingly.

Dimenhydrinate should be used with caution in patients having conditions which might be aggravated by anticholinergic therapy (i. e. prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, bladder neck obstruction, narrow-angle glaucoma, bronchial asthma, or cardiac arrhythmias).

The preparation should not be injected intra-arterially.

Pediatric Patients

For infants and children especially, antihistamines in overdosage may cause hallucinations, convulsions, or death.

As in adults, antihistamines may diminish mental alertness in pediatric patients. In the young child, particularly, they may produce excitation (see CONTRAINDICATIONS ).

Precautions

General

Drowsiness may be experienced by some patients, especially with high dosage. This effect frequently is not undesirable in conditions for which the drug is used.

Information for Patients

Because of the potential for drowsiness, patients taking Dimenhydrinate should be cautioned against operating automobiles or dangerous machinery (see WARNINGS ).

Carcinogenesis, Mutagenesis, Impairment of Fertility

Mutagenicity screening tests performed with Dimenhydrinate, diphenhydramine, and 8-chlorotheophylline produced positive results in the bacterial systems and negative results in the mammalian systems. There are no human data that indicate Dimenhydrinate is a carcinogen or mutagen or that it impairs fertility.

Pregnancy

Pregnancy Category B.

Reproduction studies have been performed in rats at doses up to 20 times the human dose, and in rabbits at doses up to 25 times the human dose (on a mg/kg basis), and have revealed no evidence of impaired fertility or harm to the fetus due to Dimenhydrinate. There are no adequate and well-controlled studies in pregnant women. However, clinical studies in pregnant women have not indicated that Dimenhydrinate increases the risk of abnormalities when administered in any trimester of pregnancy. It would appear that the possibility of fetal harm is remote when the drug is used during pregnancy. Nevertheless, because the studies in humans cannot rule out the possibility of harm, Dimenhydrinate should be used during pregnancy only if clearly needed.

Labor and Delivery

The safety of Dimenhydrinate given during labor and delivery has not been established. Reports have indicated Dimenhydrinate may have an oxytocic effect. Caution is advised when this effect is unwanted or in situations where it may prove detrimental.

Nursing Mothers

Small amounts of Dimenhydrinate are excreted in breast milk. Because of the potential for adverse reactions in nursing infants from Dimenhydrinate, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Adverse Reactions

The most frequent adverse reaction to Dimenhydrinate is drowsiness. Dizziness may also occur. Symptoms of dry mouth, nose and throat, blurred vision, difficult or painful urination, headache, anorexia, nervousness, restlessness or insomnia (especially in pediatric patients), skin rash, thickening of bronchial secretions, tachycardia, epigastric distress, lassitude, excitation, and nausea have been reported.

Overdosage

Drowsiness is the usual clinical side effect. Convulsions, coma, and respiratory depression may occur with massive overdosage. No specific antidote is known. If respiratory depression occurs, mechanically assisted respiration should be initiated and oxygen should be administered. Convulsions should be treated with appropriate doses of diazepam. Phenobarbital (5 to 6 mg/kg) may be given to control convulsions in pediatric patients.

The oral LD 50 in mice and rats is 203 mg/kg and 1320 mg/kg, respectively. The intraperitoneal LD 50 in mice is 149 mg/kg.

Dimenhydrinate Dosage and Administration

Dimenhydrinate in the injectable form is indicated when the oral form is impractical.

Adults

Nausea or vomiting may be expected to be controlled for approximately 4 hours with 50 mg, and prevented by a similar dose every 4 hours. Its administration may be attended by some degree of drowsiness in some patients, and 100 mg every 4 hours may be given in conditions in which drowsiness is not objectionable or is even desirable.

For intramuscular administration, each milliliter (50 mg) of solution is injected as needed, but for intravenous administration, each milliliter (50 mg) of solution must be diluted in 10 mL of 0.9% Sodium Chloride Injection, USP and injected over a period of 2 minutes.

Pediatric

For intramuscular administration, 1.25 mg/kg of body weight or 37.5 mg/m 2 of body surface area is administered four times daily. The maximum dose should not exceed 300 mg daily (see CONTRAINDICATIONS ).

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

How is Dimenhydrinate Supplied

Dimenhydrinate Injection, USP, 50 mg/mL is available in multiple dose amber vials, as follows:

Zeto Wine Cheese Shop Greensboro Nc Unique Corporate Gifts, Gift Baskets, Corporate Gift Baskets, Ze

ZETO The wine destination!

Order now. 336.574.2850 Zeto 335 Battleground Ave. Greensboro, NC 27401 EMAIL: Zeto@ZetoWines. com be sure that you type ZetoWines as plural or it will bounce back. Thank you. E-mail: zetodgd@ msn. com (You must type the email address into your email's TO: box -- do not cut and paste, please)

We reserve the right to correct typos. Thank you.

Zeto discounts most cases (12-bottle cases) 10%--mix and match or solid.

Wines priced NET are already discounted and no additional discounts apply. Thank you.

Small production wines. Corporate gifts . Wine cellars, wine storage units. Gift baskets . Gift certificates. Vinomatic wine vending gift card. Artisanal cheeses.

2013 Copyright Zeto, Inc. All rights reserved.

Text, photos and other aspects of this web site may not be copied nor in any way reproduced without written permission or written agreement from Zeto, Inc. officer.

Difusel, Difusel

Difusel

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Tetragynon Indication, Action Of Tetragynon, Interactions, Tetragynon

Tetragynon [in more detail]

Used as an oral contraceptive to prevent pregnancy

Tetragynon Mechanism Of Action:

Tetragynon binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Tetragynon will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.

Tetragynon Drug Interactions:

Food Interactions:

Avoid alcohol. Take with food. Avoid excessive quantities of coffee or tea (Caffeine). Increase dietary intake of magnesium, folate, vitamin B6, B12, and/or consider taking a multivitamin. Take at the same time everyday.

Tetragynon Chemical Formula:

Evolent Health Reviews, Elovent

Evolent Health Reviews

- Talented colleagues across all levels of the organization - Great mission, and mission orientation is shared broadly by management and employees - Top notch benefits and market competitive comp - Interesting, challenging work in most groups - Work with some of the best minds in healthcare, both within Evolent and at our partners

- There is at times a material lack of role clarity both within and across groups as the company continues to grow at a rapid pace, resulting in some duplicated work and the occasional inter-organizational conflict - Many tools available for managing work/life balance (generous vacation policy, tele-working, etc.), however it's a busy place so your really have to assert yourself to keep from getting overloaded

Advice to Management

Focus on keeping the organization nimble and maintaining the wonderful culture as we continue to grow.

I have been working at Evolent Health (Less than a year)

I've worked for Evolent for about 3 months. I came from a huge hospital system that never rewarded employees for there above and beyond work. Ive always been an above and beyond worker because I believe in elevating myself and growth. This is one of the reasons I chose this organization. I will definitely say that Evolent lives up to their values. The open culture is amazing, I don't feel that directors and execs walk around with their nose held high like most companies I've worked. They actually listen to those With REAL knowledge and expertise. I have already been rewarded for my work, and above and beyond efforts. I'm thanked everyday by people I don't even really work with. I am very greatful to work for such an amazing organization and great group of people. Even though my area of the job needs process improvement ASAP I believe with the right staff and continuing to listen to those that know what they are doing will put everything in place in the near future. I look back at my old job of 5 years and it makes me sick how I was never rewarded for my work or even shown appreciation for being a valuable employee. I come here doing the same thing and I'm noticed right away. This is a company that as long as you bring some type of value and be an asset to them, they will recognize your strengths and you can be rewarded. It may be different in other areas I'm not sure, but I love my job, the challenge, the rewards, the pay, PTO, benefits, working remote EVERYTHING.

I have No cons so far.

I have been working at Evolent Health full-time (More than a year)

Evolent Health is an outstanding organization. I've never worked around a smarter, more dedicated group of employees in my 20+ years in the workforce. This company is so dedicated to our mission and clients that I literally see people living our values every single day in their efforts to "Change the Health of the Nation by Changing the Way Healthcare is Delivered."

A few specific positives I want to point are: 1. Incredibly smart colleagues who have done and are doing great things. 2. A leadership team that truly cares about the culture and work environment. No, it's not all perfect, but when you see the senior leadership team digging in on tough, cultural and leadership situations, with a focus on creating the best organization we can, I have to be proud of where I work. 3. Great benefits and competitive compensation. 4. If you want to grow your skills and career, it is supported at Evolent Health. You will be challenged if you ask to grow.

The company is growing incredibly fast and you are going to have some challenges when you are attaching the landing gear of the plane while it is in the air. So, yes, there are issues around communication, role clarity and prioritization, but I know the senior leaders are well aware of those things and working as hard as they can to fix them.

Advice to Management

Keep focusing on communication, culture, prioritization, and role clarity. Protect the culture at all costs and even focus more on it to make sure it stays the same or better as the company continues to grow.

Have worked here for awhile. Ok benefits. good PTO, causal wear is a plus. Work hours are doable.

All talk and no action, feed us all a list of wonderful things to come and nothing. Treats different levels of employees different. Often a basic level employees come off as more than they really are due to management allowing it to happen. Management has a "click" of chosen employees. If your not in the "click" then you go nowhere. New management hired in is allowed to get away with treatment of employees that is less than professional. Nothing is done about it, senior management just turns their heads on it as does HR.

Advice to Management

Treat all employees the same as if they matter. Stop assuming the negative. If a error is made, it happens stop degrading the employee for it.

Managing The Symptoms Of Menopause, Kliogest

Menopause is the cessation of menstruation or last period. It marks the end of a woman’s fertile years when the ovaries produce lower levels of the reproductive hormones oestrogen and progesterone. The average age for menopause in New Zealand is 51.5 years but it can occur anytime between the ages of 42 and 56. Perimenopause is the period of five or so years up to the last period when menstruation becomes irregular or occurs less often and eventually ceases. During this time hormone levels change and changes begin to occur in the body. After menopause the body achieves a new hormonal balance, however during the transition phase, the changes in hormone levels can have a number of effects on women.

The medicalisation of menopause

Over the last fifty years western medicine has increasingly defined menopause as a condition that must be treated. The redefinition and medicalisation of menopause was initially promoted by the makers of hormone replacement therapy but has also been used to advantage by people who manufacture other products. However, menopause is not an illness. It is a natural phase in life, like puberty, pregnancy and childbirth. Even though menopause is not an illness, some of the symptoms of the hormonal changes can cause temporary discomfort.

Symptoms

How menopause affects individual women is influenced by biological and social factors, including genetics, physical and mental health, diet, lifestyle, and social and cultural attitudes toward older women. Menopause experiences vary among individual women, and among different cultures.

Some of the common reported symptoms are:

Irregular periods (when periods come closer together or further apart), and when blood flow becomes lighter or heavier

hot flushes

night sweats

headaches and migraines

disturbed sleep patterns

vaginal dryness

joint pain

fatigue

short-term memory problems

dry eyes

dizziness

itchy or ‘creepy’ skin

mood swings

anxiety and irritability

lower libido or sex drive

difficulty concentrating and making decisions

Managing Menopause

Adequate exercise, a healthy, balanced diet, taking time for rest and relaxation, and smoking cessation can all help address the symptoms of menopause.

Hot Flushes and night sweats

Up to 80% of women experience hot flushes but they tend to go away within one to two years. Common triggers for hot flushes are caffeine, alcohol, and spicy food. Traditional or natural remedies that women have reported to be useful include a diet rich in legumes, grains, nuts and seeds, sage tea, black cohosh, or acupuncture.

Hormone Replacement Therapy

After menopause it is normal to have lower levels of oestrogen and progesterone. Hormone replacement therapy (HRT) (usually a combination of progesterone and oestrogen) may be prescribed for women during perimenopause; following surgically induced menopause; and sometimes post-menopausally. Hormone replacement therapy artificially boosts hormone levels with the aim of alleviating some of the conditions caused by diminished levels of oestrogen and progesterone. While hormone replacement therapy is effective at addressing some symptoms, it also carries serious risk. Many studies suggest that HRT should be taken at the lowest dose for the shortest period of time necessary to control symptoms, and the need for continuing treatment should be reviewed at 6-monthly intervals. HRT use for prevention of chronic disease is not recommended.

HRT Effects

HRT is effective at reducing or stopping hot flushes and night sweats.

HRT can also help with vaginal dryness, reducing pain during sex.

HRT is not effective at improving psychological symptoms, general wellbeing and mental functioning.

HRT Risks

Even short-term use of combined HRT (oestrogen and progesterone) is associated with an increased risk of breast cancer, melanoma, lung cancer (in current smokers), ovarian cancer, stroke, blood clots, and a doubled risk of dementia for women over 65.

There is an increased risk for heart attacks when a woman is more than ten years past menopause. Oestrogen alone carries an increased risk of stroke, blood clots and dementia. It increases the risk of ovarian cancer. It may increase the risk of breast cancer. Oestrogen alone increases the risk of cancer of the lining of the uterus.

The Women’s Health Initiative trial

The Women’s Health Initiative (WHI) trial of 161,808 healthy women aged 50 – 79 is the largest and most rigorous scientific study ever done on the long-term health effects of HRT. The study was stopped on July 7, 2002 after an average of 5.6 years follow-up because of increased risks of cardiovascular disease and breast cancer in women taking HRT compared with those taking placebo (dummy pills). The study showed that the risks exceeded the benefits, with women taking HRT at higher risk for heart disease, blood clots, stroke, and breast cancer, but at lower risk for fracture and colon cancer. The trial investigators advised that within 5 years, 1 in 100 women using HRT would have a serious adverse event.

A 2008 follow-up of participants from the WHI trial found that three years after women stopped taking HRT the increased risk of heart disease was diminished, but overall risks, including risks of stroke, blood clots, and cancer, remained high. It also found that the death rate among women who had been most regular with their HRT during the trial was 53 percent higher in the hormone group than in the placebo group.

NZ Medsafe Guidelines recommend that

HRT should only be used where menopausal symptoms are troublesome and women are fully informed of the risks.

HRT should be used at the lowest dose and for the shortest time possible. The continued use of HRT should be reviewed by women and their doctors at the time of the next prescription or within 3 months whichever is sooner.

Coming off HRT

If you have been on HRT for some time stopping suddenly can be stressful on the body, which may have become dependent on the artificial supply of hormones, and can cause symptoms to return. The body’s reliance on HRT will probably be higher for women who are on a high dose of HRT, and for those who have been taking HRT for a long time.

Many studies recommend gradually weaning off HRT over a period of 2-4 months, unless there are health factors that require a more immediate cessation. This will give your body time to increase its own production of hormones it has been relying on HRT for. Talk with your doctor if you have concerns or would like advice on coming off HRT.

You can support yourself through the process of coming off HRT by looking after yourself, ensuring you are eating right, exercising regularly, and finding time for sufficient rest and relaxation.

Bio-identical hormones

Bio-identical hormones include progesterone, DHEA, testosterone, and the oestrogens estradiol, estriol, and estrone.

Bio-identical or ‘natural’ hormones are produced in the laboratory. Plant hormones are used as a base from which to synthesise hormones that are found in the human body. Bio-identical hormones may be compounded in individually tailored doses and combinations and come as capsules, creams, patches, gels, lozenges, suppositories and under-the-tongue drops.

There is no evidence to confirm that bio-identical hormones are safer than standard HRT and whether they carry the same risks for breast cancer, ovarian cancer, endometrial cancer, heart disease and stroke. Until reliable clinical evidence proves otherwise, it must be assumed that the risks of bio-identical hormones are similar to the risks of hormone replacement therapy.

References

Mid-life Energy & Happiness, by Gill Sanson 1999 Penguin: Auckland

Escudo - Definicion, Escudo

Online Language Dictionaries

Del verbo escudar . (conjugar ) escudo es: 1ª persona singular (yo) presente indicativo escudó es: 3ª persona singular (el/ella/usted) preterito indicativo

Diccionario de la lengua espanola © 2005 Espasa-Calpe:

escudo

m. Arma defensiva de metal, madera o cuero para cubrirse y resguardar el cuerpo, que se llevaba en el brazo izquierdo: se protegia con el escudo mientras asestaba golpes con la maza.

Persona o cosa que sirve de proteccion o parapeto: tomo un rehen como escudo.

Superficie o espacio con el emblema o las armas de una nacion, de una ciudad, de una familia, de una corporacion o asociacion, etc.: se hizo grabar el escudo de su apellido en un anillo.

Antigua moneda espanola de oro y, despues, de plata.

Moneda chilena vigente desde 1959 hasta 1974.

Unidad monetaria de Portugal y Cabo Verde.

geol. Plataforma compuesta por rocas consolidadas que constituye el nucleo de los continentes.

Diccionario de la lengua espanola © 2005 Espasa-Calpe:

escudar conjugar ?

tr. Resguardar con el escudo, oponiendolo al golpe del contrario. Tambien prnl.

tr. Resguardar y defender a una persona del peligro que le esta amenazando: escudo a su hijo durante el tiroteo.

prnl. Valerse uno de algun medio como justificacion para salir de un riesgo o compromiso: se escudo en su dolor de cabeza para librarse de el.

' escudo ' aparece tambien en las siguientes entradas:

Preguntas en los foros con la(s) palabra(s) 'escudo' en el titulo:

Incepta Pharmaceuticals, Oticlor

Oticlor 500 Capsule. Each capsule contains Cefaclor Monohydrate USP 524.46 mg equivalent to Cefaclor 500 mg.

Oticlor Dry suspension: After reconstitution, each 5 ml suspension contains Cefaclor Monohydrate USP 131.11 mg equivalent to Cefaclor 125 mg.

Oticlor Paediatric drops: After reconstitution, each ml drop contains Cefaclor Monohydrate USP 104.9 mg equivalent to Cefaclor 100 mg.

Cefaclor, a second generation cephalosporin, demonstrates the bactericidal action by inhibiting cell wall synthesis. It is active against the following organisms In Vitro:

Aerobes, Gram-positive: Streptococcus pneumoniae, Streptococcus pyogenes (Group A beta-haemolytic streptococci) and Staphylococci.

Aerobes, Gram-negative: Moraxella catarrhalis, Haemophilus influenzae, Escherichia coli, Proteus mirabilis, Klebsiella sp.,Citobacter diversus and Neisseria gonorrhoeae.

Anaerobes: Propionibacteria acnes, Bacteroides sp. (excluding Bacteroides fragilis), Peptococci and Peptostreptococcus sp.

Oticlor is indicated in the treatment of the following infections:

Lower respiratory tract infections, including pneumonia, bronchitis and acute exacerbation of chronic bronchitis

Upper respiratory tract infections, including pharyngitis and tonsillitis

Urinary tract infections, including pyelonephritis and cystitis

Skin and soft tissue infections

Oticlor is administered orally. Children: The usual recommended dosage for children is 20 mg/kg/day in divided doses every 8 hours. The dose of Oticlor suspension and paediatric drops for children is given in the following:

Age Oticlor suspension Oticlor Paediatric Drops 1 month - 1 year 2.5 ml t. i.d. 0.625 ml t. i.d 1 year - 5 year 5 ml t. i.d. 1.25 ml t. i.d over 5 years 10 ml t. i.d 2.5 ml t. i.d

In more serious infections, such as otitis media, or those caused by less susceptible organisms, 40 mg/kg/day is recommended, with a maximum dosage of 1 gm/day. Safety and efficacy have not been established for use in infants aged less than 1 month. Adults: The usual adult dose is 250 mg every 8 hours. For bronchitis, the dosage is 250 mg administered 3 times daily. A dosage of 250 mg administered 3 times daily for 10 days is recommended for sinusitis. For more severe infections, such as pneumonia, or those caused by less susceptible organisms, dose may be doubled. Cefaclor may be administered safely in the presence of impaired renal function. Under such conditions, dosage is usually unchanged.

Most adverse effects reported with Cefaclor are similar to those reported with other oral cephalosporins. The most frequent adverse effects reported include gastrointestinal effects (nausea, vomiting, diarrhea) headache and rash. Rarely, Serum sickness-like reactions consisting of erythema multiforme, urticaria accompanied by arthritis, arthralgia, irritability and fever have been reported.

Cefaclor should be administered with caution in the presence of markedly impaired renal function. Dosage adjustments for patients with moderate or severe renal impairment are not usually required.

Cefaclor is contraindicated in patients with known hypersensitivity to cephalosporin group of antibiotics. It is also contraindicated in porphyria.

Use in Pregnancy & Lactation

Pregnancy: Animal studies have shown no evidence of impaired fertility or teratogenicity. However, since there are no adequate or well-controlled studies in pregnant women, caution should be exercised when prescribing for the pregnant women. Lactation: Small amount of Cefaclor have been detected in breast milk following administration of single 500 mg dose. As the effect on nursing infants is not known, caution should be exercised when Cefaclor is administered to a nursing woman.

There have been reports of increased anticoagulant effect when Cefaclor and oral anticoagulants were administered concomitantly. The renal excretion of Cefaclor is inhibited by probenecid.

Direction for reconstitution of suspension For 100 ml suspension: Add 60 ml (12 measuring spoonful) of boiled and cooled water to the dry powder of the bottle. For ease of preparation, add water to the bottle in two proportions. Shake well after each addition until all the powder is in suspension. Paediatric drops: Add 10 ml (2 measuring spoonful) of boiled and cooled water to the bottle and shake vigorously. Note: Shake the suspension and paediatric drop well before each use. Keep the bottle tightly closed. The reconstituted suspension should be stored in a cool and dry place, preferably in refrigerator. The made up suspension can be used within 7 days if it is stored at room temperature and 14 days if it is kept in refrigerator.

The symptoms following an overdose of Cefaclor may include nausea, vomiting, epigastric distress, and diarrhea. The severity of the epigastric distress and diarrhea is dose related. Unless 5 times the normal dose of Cefaclor has been ingested, gastrointestinal lavage will not be necessary.

Oticlor 500 Capsule. Box containing 3 Alu-Alu blister strips of 4 capsules. Oticlor Dry suspension: Bottle containing dry powder for 100 ml suspension. Oticlor Paediatric drops: Bottle containing dry powder for 15 ml drops.

Levoxin 250: Each film coated tablet contains Levofloxacin Hemihydrate INN equivalent to Levofloxacin 250 mg.

Levoxin 500: Each film coated tablet contains Levofloxacin Hemihydrate INN equivalent to Levofloxacin 500 mg.

Levoxin 750: Each film coated tablet contains Levofloxacin Hemihydrate INN equivalent to Levofloxacin 750 mg.

Levoxin 100 ml oral solution: Each 5 ml solution contains Levofloxacin Hemihydrate INN equivalent to Levofloxacin 125 mg.

Levoxin IV Infusion: Each 100 ml solution contains Levofloxacin Hemihydrate INN equivalent to Levofloxacin 500 mg.

Levofloxacin is a synthetic, broad-spectrum, third generation fluoroquinolone derivative antibacterial agent. Chemically levofloxacin is a chiral fluorinated carboxyquinolone.

Levofloxacin is indicated for the treatment of mild, moderate, and severe infections caused by susceptible strains of the designated micro-organisms in the condition listed below:

- Acute maxillary sinusitis due to Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis

- Acute bacterial exacerbation of chronic bronchitis due to Staphylococcus aureus, Streptococcus pneumoniae

- Haemophilus influenzae, or Moraxella catarrhalis

- Community-acquired pneumonia due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus

- influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, or Mycoplasma pneumoniae

- Uncomplicated & complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, or Staphylococcus saprophyticus

- Acute pyelonephritis caused by Escherichia coli

- Uncomplicated & complicated skin and soft tissue infections including abscesses, cellulitis, furuncles, impetigo, pyoderma, wound infections, due to Staphylococcus aureus, Streptococcus pyogenes, Proteus mirabilis or Enterococcus faecalis

- Enteric infections caused by Enterobacter sp. Escherichia coli, Campylobacter sp. Vibrio cholerae, Shigella sp. Salmonella sp.

Levoxin Tablet: The usual dose of Levoxin Tablets is 250 mg or 500 mg or 750 mg administered orally every 24 hours. Levoxin tablets can be administered without regard to food. Levofloxacin oral solution should be taken 1 hour before, or 2 hours after eating.

Levoxin Injection: Levoxin injection should only be administered by intravenous infusion. It is not for intramuscular, intrathecal, intraperitoneal, or subcutaneous administration. The usual dose of Levoxin injection is 250 mg or 500 mg administered by slow infusion over 60 minutes every 24 hours or 750 mg administered by slow infusion over 90 minutes every 24 hours. Since the Levoxin injections are for single-use only, any unused portion should be discarded. Additives or other medications should not be added to Levoxin Injection or infused simultaneously through the same intravenous line.

Adult - Acute sinusitis: 500 mg once daily for 10-14 days, or 750 mg once daily for 5 days - Exacerbation of chronic bronchitis: 500 mg once daily for 7 days, or 750 mg once daily for 3 days (Uncomplicated), 750 mg once daily for 5 days (Complicated) - Community-acquired pneumonia: 500 mg once daily for 7-14 days, or 750 mg once daily for 5 days - Uncomplicated urinary-tract infections: 250 mg once daily for 3 days - Complicated urinary-tract infections and acute pyelonephritis: 250 mg once daily for 7-10 days - Uncomplicated skin and soft-tissue infections: 500 mg once daily for 7- 10 days - Complicated skin and soft-tissue infections: 750 mg once daily for 7-14 days - Enteric fever: 500 mg once daily for 7-14 days - Diarrhea, cholera, shigellosis & enteritis: - - Mild to moderate case: 500 mg (single dose) - - Moderate to sever case: 500 mg once daily for 3 days

Children - Children 6 months to 5 years:10 mg/kg every 24 hours

In each case, sequential therapy (intravenous to oral) may be instituted at the discretion of the physician.

Levofloxacin is generally well tolerated. However, a few side-effects can usually be seen. Side-effects include: nausea, vomiting, diarrhea, abdominal pain, flatulence and rare occurrence of phototoxicity ( 0.1%). Side-effects that may be seen very rarely include tremors, depression, anxiety, confusion etc.

The following measures should be taken during administration of Levofloxacin:

- Levofloxacin Injection should only be administered by slow intravenous infusion over a period of 60 or 90 minutes depending on the dosage.

- While administrating Levofloxacin, adequate amount of water should be taken to avoid concentrated form of urine.

- Dose adjustment should be exercised during Levofloxacin administration in presence of renal insufficiency.

Levoxin eye drops should not be injected subconjunctially, nor should it be introduced directly into the anterior chamber of the eye. Avoid contaminating the applicator tip with material from the eye, fingers or other source.

Levofloxacin is contraindicated in patients with a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents, or any other components of this product.

Use in Pregnancy & Lactation

Levofloxacin is not recommended for use during pregnancy or nursing, as the effects on the unborn child or nursing infant are unknown.

No quinolone should be co-administered with any solution containing multivalent cations, e. g. magnesium, through the same intravenous line. Antacids, Iron and Adsorbents reduce absorption of Levofloxacin. NSAID may increase the risk of CNS stimulation. Warfarin may increase the risk of bleeding.

Levofloxacin exhibits a low potential for acute toxicity. However, in the events of an acute overdosage, the stomach should be emptied. The patients should be kept under observation and appropriate hydration should be maintained.

Levoxin 250. Each box contains 3 blister strips of 10 tablets. Levoxin 500. Each box contains 2 blister strips of 10 tablets. Levoxin 750. Each box contains 1 blister strip of 10 tablets. Levoxin 100 ml oral solution: Each bottle contains 100 ml oral solution. Levoxin IV Infusion: Each box contains 1 bag of 100 ml solution for injection.

Instructions for the Use of Levoxin Infusion: 1. Check the container for minute leaks by squeezing the inner bag firmly. If leaks are found, or if the seal is not intact, discard the solution. 2. Do not use if the solution is cloudy or a precipitate is present. 3. Do not use flexible containers in series connections. 4. Close flow control clamp of administration set. 5. Remove cover from port at bottom of container. 6. Insert piercing pin of administration set into port with a twisting motion until the pin is firmly seated. 7. Suspend container from hanger. 8. Squeeze and release drip chamber to establish proper fluid level in chamber during infusion of Levoxin Injection. 9. Open flow control clamp to expel air from set. Close clamp. 10. Regulate rate of administration with flow control clamp.

Products from the same therapeutic group

Doxyhexal Tablets, Doxyhexal

Generic Name: Doxycycline monohydrate Product Name: Doxyhexal Tablets

Indication

Doxycycline is used in the treatment of the following conditions Acne Infections caused by various bacteria including certain sexually transmitted infections Pneumonia Exacerbation of chronic bronchitis Sinusitis Prostatitis Prevention and treatment of Malaria

Action

Doxycycline prevents bacteria from replicating

Dose advice

Adults The initial dose is 200 mg as a single dose on the first day of treatment Following this 100 mg should be given once a day The maximum recommended dose is 200 mg a day

Children (>8 years) The initial dose is 2 mg/kg twice daily on the first day of treatment up to a maximum dose of 200 mg a day Following this then 2 mg/kg is given once daily up to a maximum 100 mg a day In the case of a serious infections the dose may be increased to 4 mg/kg/day up to a maximum of 200mg given as one of two divided doses The dose amount should be rounded to the nearest 25 mg.

Acne 50 mg a day for at least 6 weeks This dose may then be altered depending on the individual patients response.

Chlamydia infection 100 mg twice daily for 1a??3 weeks This dose may change depending on the site and the severity of the infection.

Schedule

Common side effects

Nausea Vomiting Indigestion Tooth discolouration Reduced bone growth in children aged less than 8 years Increased skin sensitivity to light

Uncommon side effects

Rash Bone deformity Fungal infections

For further information talk to your doctor.

Aspizone, Aspizone

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Aspizone Ohta (Diclofenac)

Alendronate Sodium Pill Images - What Does Alendronate Sodium Look Like, Alendron

Alendronate sodium Images

Cuvitru Cuvitru immune globulin subcutaneous (human) is indicated as replacement therapy in the treatment.

Yosprala Yosprala (aspirin and omeprazole) is a platelet aggregation inhibitor and proton pump inhibitor.

Erelzi Erelzi (etanercept-szzs) is a tumor necrosis factor (TNF) blocker biosimilar to Enbrel indicated.

Troxyca ER Troxyca ER (oxycodone hydrochloride and naltrexone hydrochloride) is an extended-release.

Alendronate Rating

18 User Reviews 4.7 /10

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Prilozheniya Na Google Play – La Ban Phong Thuy, Dia-Ban

Описание

La ban Phong th?y (La kinh – FengShui Compass) la ?ng d?ng MI?N PHI h? tr? do hu?ng nha, hu?ng c?a, hu?ng b?p, hu?ng phong lam vi?c… r?t thich h?p cho cac th?y, cac b?n nghien c?u phong th?y…

V?i kim ch? nam chinh xac, la ban t? xoay do hu?ng, t?a c?a v? tri ngu?i s? d?ng.

S? h?u ngay ?ng d?ng La ban Phong th?y v?i cac ch?c nang va ti?n ich n?i b?t sau:

- H? tr? lo?i La ban Bat quai ti?n thien va La ban 24 phuong v? - Tuy ch?n hi?n th? b?ng ch?c nang khoa la ban - Cac ch?c nang Hi?u ch?nh c?m bi?n la ban phu h?p v?i t?ng dong may. (M?t s? di?n tho?i va may tinh b?ng ch? hu?ng Dong => B?c, b?n c?n ch?n hi?u ch?nh 90 d?).

Va r?t nhi?u tinh nang khac dang t?ng ngay du?c hoan thi?n.

?ng d?ng du?c thi?t k? d? ch?y tren cac di?n tho?i di d?ng va may tinh b?ng h? di?u hanh Android co h? tr? c?m bi?n la ban s?.

CHU Y KHI S? D?NG LA BAN: Khi do khong d?ng g?n cac may tinh, thi?t b? di?n, o to; d?ng th?i thao t?t c? cac v?t b?ng kim lo?i tren ngu?i… d? k?t qu? do du?c chinh xac.

M?i gop y ho?c thong bao l?i, vui long lien h? v?i chung toi theo s? DT: 04.6281.2997 ho?c g?i v? hom mail gop y: lichngaytot@gmail. com

*** Khi la ban d?ng yen ho?c sai hu?ng: tru?c khi cho nh?n xet tieu c?c va 1* hay ki?m tra xem may c?a b?n co c?m bi?n la ban s? hay khong ho?c c?n hi?u ch?nh l?i la ban trong ph?n Cai d?t.

Фэн-шуй компас (La бизнес - фэншуй Компас) это бесплатное приложение, которое поддерживает направление измерения, к двери, в сторону кухни, направление рабочего помещения. очень подходит для вас, вы будете изучать фэн-шуй.

С точностью компаса, автоматического поворота компаса измерения направлении, координаты положения пользователя.

Право собственности фэн-шуй компас приложение с функциональностью и выдающихся объектов следующем:

- Поддержка Компас Bowl черту, денег природного и компаса азимуту 24 - Дополнительный дисплей с функцией компаса ключей - Датчик функция калибровки компас подходит для каждой серии. (Некоторые телефоны и планшеты к востоку => Северная, необходимо выбрать регулировка 90 градусов).

И многие другие функции будут завершены каждый день.

Приложение предназначено для работы на мобильных телефонах и планшетных Android операционной системе, поддерживающей цифровой датчик компаса.

БУДЬТЕ ОСТОРОЖНЫ ПРИ КОМПАС: При измерении не стоят возле компьютеров, электрооборудования, автомобилей; и снимите все металлические предметы на. для точного измерения результатов.

Любые предложения или заметили ошибку, пожалуйста, свяжитесь с нами по тел: 04.6281.2997 или отправить комментарии на почтовый ящик: lichngaytot@gmail. com

*** Когда стоит на месте или неправильно направление по компасу, прежде чем дать отрицательный результат воздействия и 1 * проверить, если ваш компьютер имеет цифровой датчик компаса или нет, или нужно, чтобы заново откалибровать компас в разделе Настройки.

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La ban Phong th?y (La kinh) v?i kim ch? nam chinh xac.

Du?c thi?t k? ch?y tren cac di?n tho?i di d?ng va may tinh b?ng h? di?u hanh Android t? 2.1 tr? len va co h? tr? c?m bi?n la ban s? c?a cac hang: Samsung, HTC, Sony, LG. V?i la ban t? xoay d? do hu?ng, t?a c?a v? tri ngu?i s? d?ng.

R?t h?u ich cho cac th?y, cac b?n nghien c?u phong th?y la kinh. d? do hu?ng nha, hu?ng c?a, hu?ng b?p, hu?ng ban lam vi?c. Ho?c don gi?n b?n co th? dung nhu la ban thong thu?ng.

Ch?c nang: Do hu?ng nha, hu?ng c?a, hu?ng b?p, hu?ng ban lam vi?c. v?i d? chinh xac r?t cao (True North v?i GPS).

- Bat Quai Ti?n thien - Do hu?ng 24 son chinh cham - Do 60 m?ch long th?u d?a - Do 72 m?ch long xuyen son - Do 3 vong hu?ng: Vong chinh cham, Phong d?a ban, Vong thien ban - Do 120 phan kim - Tuy ch?n hi?n th? b?ng ch?c nang khoa d? d?nh v? - Luu hinh ?nh la ban phong thuy - la kinh trong may d? ti?n tra c?u ho?c chia s? - C?nh bao khi d? chinh xac th?p

*** Khi hu?ng hi?n th? sai so v?i th?c t? b?n vui long s? d?ng ch?c nang hi?u ch?nh: Menu-> Hi?u ch?nh la ban. VD: 1 s? di?n tho?i va MTB ch? hu?ng Dong ->B?c, b?n c?n ch?n hi?u ch?nh 90°. Sai s? con co th? do v? b?o v? kim lo?i ma b?n dang dung ho?c vung co t? tru?ng khong ?n d?nh.

***Ghi chu quan tr?ng: Gi? la ban trong vung t? tru?ng ?n d?nh, xa may tinh, di?n tho?i/MTB khac, day cap di?n va cac thi?t b? di?n d? k?t qu? do du?c chinh xac *Vui long xem video hu?ng d?n cach hi?u ch?nh c?m bi?n la ban t?i day: http://www. youtube. com/watch? v=b6ta_eV5xrE

*** La ban phong thuy - La kinh hoan toan mi?n phi v?i qu?ng cao, b?n co th? mua IN-APP d? t?t qu?ng cao.

Ла Пан Фонг Туи (Ла кинь) ВОИ Ким Чи Нам Chinh XAC.

Du?c Thi?t Ke Чай Трен CAC Di?n tho?i ди D?ng vA может tinh Взрыва он di?u Хан Android 2.1 t? ТРО LEN vA Co Хо ТРО камерой Bien-ла-Ban SO c?a CAC повесить: Samsung, HTC, Sony, LG. Вой ла Пан t? xoay дже DJO Huong, Тоа c?a VI Tri ngu?i Су навоза.

Крыса HUU Ich чо CAC Тай, CAC запрет Нгьен CUU Фонг Туи Кинь ла. дже DJO Huong nha, Huong Куа, Huong НПД, Huong запрет Лам VIEC. ?hoac DJON Джан запрет Co навоз NHU ла Бан Тонг Thuong.

Чук Нанг: DJO Huong nha, Huong Куа, Huong НПД, Huong запрет Лам VIEC. v?i DJO Chinh XAC Крыса САО (True North v?i GPS).

- Летучая мышь Quai Тянь Thien - DJO Huong 24 сын Chinh Cham - DJO 60 Мах долго Тау DJIA - DJO 72 Мах Лонгсюен Son - DJO 3-вонгов Huong:-вонгов Chinh Cham, Phong DJIA запрет, запрет-вонгов Thien - DJO 120 Фан Ким - Туй Чон Hi?n Тхи Чук Взрыва Нанг Хоа дже Динь VI - Лу Hinh Ань ла запрет Фонг Туи - ла кинь Чонг может дже Тянь тра CUU ?hoac цзя SE - Кань Бао хи DJO Chinh XAC Тап

*** Хи Huong Hi?n Тхи сай так v?i th?c t? запрет VUI длинных СУ Зунг Чук Нанг Hieu Chinh: Меню-> Hieu Chinh ла запрет. В. Д. 1, так Di?n tho?i vA MTB Чи Huong Dong -> Бык, запрет может Чон Hieu Chinh 90 °. Саи так, Con Co сделать ВО B?o В. Э. Ким Loai mA запрет Dang Зунг ?hoac Вунг Co t? Tru?ng khong на Динь.

*** Ги Чу цюань Чонг: ГИУ ла запрет Чонг Ванг t? Tru?ng на Динь, ха может tinh, Di?n tho?i / MTB Кхак, день Cap Di?n vA CAC Thi?t b? Di?n дже KET условием DJO du?c Chinh XAC * VUI длительного XEM видео Huong Дэн Кать Hieu Chinh камерой Bien-ла-Ban Tai Djay: http://www. youtube. com/watch? v=b6ta_eV5xrE

*** Ла запрет Фонг Туи - Ла кинь Хоан Тоан миной Phi v?i Qu?ng Цао, запрет Co муа In-App дже ТАТ Qu?ng Цао.

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Odoxil Suspension - Uses, Side-Effects, Reviews, Composition, Interactions, Precautions, Substitutes

Odoxil Suspension

Odoxil Suspension - Uses, Composition, Side Effects and Reviews

Odoxil Suspension is indicated for the treatment of bacterial infections, lung or respiratory tract infections, kidney infection, bladder infection, skin and soft tissue infections, inflammation of tonsils and other conditions. Odoxil Suspension contains the following active ingredients: Cefadroxil. It is available in suspension form. Lupin manufactures Odoxil Suspension. Detailed information related to Odoxil Suspension's uses, composition, dosage, side effects and reviews is listed below:

Odoxil Suspension Uses

Odoxil Suspension is used in the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

Bacterial infections

Lung or respiratory tract infections

Kidney infection

Bladder infection

Skin and soft tissue infections

Inflammation of tonsils

Learn more: Uses (in more detail)

Odoxil Suspension Working, Mechanism of Action and Pharmacology

Odoxil Suspension improves the patient's condition by performing the following functions:

Odoxil Suspension Composition and Active Ingredients

Odoxil Suspension is composed of the following active ingredients (salts)

Please note that this medicine may be available in various strengths for each active ingredient listed above.

Odoxil Suspension Side-effects

The following is a list of possible side effects that may occur from all constituting ingredients of Odoxil Suspension. This is not a comprehensive list. These side effects are possible, but do not always occur. Some of the side effects may be rare but serious. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

If you notice other side effects not listed above, contact your doctor for medical advice. You may also report side effects to your local food and drug administration authority.

Learn more: Side-effects (in more detail)

Odoxil Suspension Precautions & How to Use

Before using this drug, inform your doctor about your current list of medications, over the counter products (e. g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e. g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

Learn more: Precautions & How to Use (in more detail)

Odoxil Suspension Frequently asked Questions

Can Odoxil Suspension be used for Bacterial infections and Lung or respiratory tract infections?

Yes, bacterial infections and lung or respiratory tract infections are among the most common reported uses for Odoxil Suspension. Please do not use Odoxil Suspension for bacterial infections and lung or respiratory tract infections without consulting first with your doctor. Click here to find out what other patients report as common uses for Odoxil Suspension.

Is it safe to drive or operate heavy machinery when consuming?

If you experience drowsiness, dizziness, hypotension or headache as side-effects when eating Odoxil Suspension medicine then it maybe not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if eating the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Odoxil Suspension. Always consult with your doctor for recommendations specific to your body and health conditions.

Is this medicine or product addictive or habit forming?

Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.

Can it be stopped immediately or do I have to slowly ween off consumption?

Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Is Odoxil Suspension safe to consume or apply when pregnant?

Please consult with your doctor for case-specific recommendations.

Is Odoxil Suspension safe while breastfeeding?

Please discuss the risks and benefits with your doctor.

Consumer Survey: Odoxil Suspension

The following are the results of on-going survey on TabletWise. com for Odoxil Suspension. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.

Uses, Effectiveness and Side-effects

Following are the uses, perceived effectiveness and perceived side-effects incidence information reported by website visitor for Odoxil Suspension:

User reported uses

No data has been collected for this survey

User reported time for results

No data has been collected for this survey

Aviane Oral Uses, Side Effects, Interactions, Pictures, Warnings - Dosing, Aviane

Aviane

Warnings

Do not use this medication if you smoke cigarettes/use tobacco and are over 35 years old. Smoking raises your risk of stroke. heart attack. blood clots. and high blood pressure from hormonal birth control (such as the pill, patch, ring). The risk of these serious problems increases with age and with the number of cigarettes you smoke. Do not smoke or use tobacco.

Uses

This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen ). It works mainly by preventing the release of an egg (ovulation ) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus (womb) to prevent attachment of a fertilized egg.

Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts. and also treat acne .

How to use Aviane

Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. The leaflet contains very important information on when to take your pills and what to do if you miss a dose. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily. Pick a time of day that is easy for you to remember, and take your pill at the same time each day.

It is very important to continue taking this medication exactly as prescribed by your doctor. Follow the package instructions to find the first tablet, start with the first tablet in the pack, and take them in the correct order. Do not skip any doses. Pregnancy is more likely if you miss pills, start a new pack late, or take your pill at a different time of the day than usual.

Taking this medication after your evening meal or at bedtime may help if you have stomach upset or nausea with the medication. You may choose to take this medication at another time of day that is easier for you to remember. No matter what dosing schedule you use, it is very important that you take this medication at the same time each day, 24 hours apart.

If you have vomiting or diarrhea within 4 hours after taking your tablet, read the Patient Information Leaflet section titled "What to Do if You Miss Tablets." Follow the instructions as if you had missed your dose because vomiting/diarrhea can stop the tablet from working.

Your pill pack contains 28 pills with active medication. Take one active pill (with hormones) once daily for 28 days in a row. After taking the last tablet in your old pack, start a new pack the next day. There is no break between packs, and there are no "reminder" tablets (tablets without medication). Most women do not have regular periods while taking this medication. You may have some bleeding or spotting. If this happens, do not stop taking your pills.

If this is the first time you are using this medication, and you are not switching from another form of hormonal birth control (such as patch, other birth control pills ), take the first tablet in the pack on the first day of your period. If your doctor directs you to start this medication on any other day, use an additional form of non-hormonal birth control (such as condoms. spermicide) for the first 7 days to prevent pregnancy until this medication has enough time to work. If you start on the first day of your period, you do not need to use back-up birth control the first week.

Ask your doctor or pharmacist for information about how to switch from other forms of hormonal birth control (such as patch, other birth control pills) to this product. If any information is unclear, consult the Patient Information Leaflet or your doctor or pharmacist.

Side Effects

Nausea, vomiting, headache. abdominal cramps /bloating. breast tenderness, swelling of the ankles /feet (retaining fluid), or weight change may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Many women will not have regular periods while taking this medication. This is normal. Vaginal bleeding /spotting is likely to occur, especially during the first few months of use. If bleeding is unusually heavy or lasts for more than 7 days in a row, contact your doctor promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: lumps in the breast. mental/mood changes (such as new/worsening depression ), unusual changes in vaginal bleeding (such as continuous spotting, sudden heavy bleeding), severe pain in the stomach /abdomen /pelvis, dark urine, yellowing eyes /skin .

This medication may rarely cause serious (sometimes fatal) problems from blood clots (such as deep vein thrombosis. heart attack, pulmonary embolism. stroke). Get medical help right away if you have: shortness of breath/rapid breathing, chest/jaw/left arm pain, unusual sweating, confusion, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, sudden/severe headaches, slurred speech, weakness on one side of the body, sudden vision changes.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

See also Warning section.

Before taking levonorgestrel/ethinyl estradiol, tell your doctor or pharmacist if you are allergic to it; or to any estrogens (such as ethinyl estradiol, mestranol); or to any progestins (such as norethindrone, desogestrel); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood clots (for example, in the legs, eyes, lungs), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, abnormal breast exam, cancer (especially endometrial and breast cancer), high cholesterol or triglyceride (blood fat) levels, depression, diabetes, family medical history (especially angioedema), gallbladder problems, severe headaches/migraines, heart problems (such as heart valve disease, irregular heartbeat, previous heart attack), history of yellowing eyes/skin (jaundice) during pregnancy or while using hormonal birth control (such as pills, patch), kidney disease, liver problems (including tumors), stroke, swelling (edema), thyroid problems, unexplained vaginal bleeding, obesity.

If you have diabetes, this medication may make it harder to control your blood sugar levels. Check your blood sugar levels regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Tell your doctor if you just had or will be having surgery or if you will be confined to a bed or chair for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using hormonal birth control. You may need to stop this medication for a time or take special precautions.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may cause blotchy, dark areas on your skin (melasma). Sunlight may worsen this effect. Avoid prolonged sun exposure, sunlamps, and tanning booths. Use a sunscreen, and wear protective clothing when outdoors.

If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Tell your eye doctor if these problems occur.

It may take longer for you to become pregnant after you stop taking birth control pills. Consult your doctor for more information.

This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. If you have just given birth or had a pregnancy loss or abortion after the first 3 months, talk with your doctor about reliable forms of birth control, and find out when it is safe to start using birth control that contains a form of estrogen, such as this medication.

This medication may decrease breast milk production. A small amount passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane), ospemifene, tamoxifen, tizanidine, tranexamic acid, a certain combination product used to treat chronic hepatitic C (ombitasvir/paritaprevir/ritonavir/dasabuvir).

Some drugs may cause hormonal birth control to work less well by decreasing the amount of birth control hormones in your body. This effect can result in pregnancy. Examples include griseofulvin, modafinil, rifamycins (such as rifampin, rifabutin), St. John's wort, drugs used to treat seizures (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate), HIV drugs (such as nelfinavir, nevirapine, ritonavir), among others.

Tell your doctor when you start any new drug, and discuss if you should use additional reliable birth control. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

This medication may interfere with certain laboratory tests (such as blood tests for clotting factors, thyroid), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this medication.

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea and vomiting, sudden/unusual vaginal bleeding.

Notes

Do not share this medication with others.

Keep all regular medical and laboratory appointments. You should have regular complete physical exams including blood pressure, breast exam, pelvic exam, and screening for cervical cancer (Pap smear). Follow your doctor's instructions for examining your breasts, and report any lumps right away. Consult your doctor for more details.

Missed Dose

Missed dose advice is different depending on the brand used and the number of doses missed. Refer to the product package information for advice on missed doses. You may need to use back-up birth control (such as condoms, spermicide) to prevent pregnancy. Ask your doctor or pharmacist if you have any questions.

If you often forget to take the pill as directed, contact your doctor to discuss switching to another form of birth control.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

Images

Enalapril Dosage Guide With Precautions, Enapril-H

Enalapril Dosage

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Initial dose (oral tablets or solution): 5 mg orally once a day Maintenance dose (oral tablets or solution): 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses

In combination with diuretics : Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Parenteral: 1.25 to 5 mg IV over a 5 minute period every 6 hours

Comments: - Clinical response is usually seen within 15 minutes after IV administration. - If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses

Comments : - Treatment is usually combined with diuretics and digitalis. - Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses

Comments : - After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. - If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension

Oral tablets or solution: Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients.

Comment : - Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Renal Dose Adjustments

CrCl 30 mL/min or less: - Oral tablets or solution: 2.5 mg once a day titrated upward until blood pressure is controlled up to a maximum of 40 mg orally daily in single or 2 divided doses - Intravenous: 0.625 mg every 6 hours and increase dose based on response

There are no data on the safety and efficacy of enalapril in neonates and pediatric patients with CrCl of less than 30 mL/min.

Liver Dose Adjustments

Data not available

Dose Adjustments

-In some patients treated with once daily dosing, the antihypertensive effect may diminish toward the end of the dosing interval. In such patients, an increase in dosage or twice daily administration should be considered. - If blood pressure is not adequately controlled with enalapril alone, a diuretic may be added. - If enalapril is added to a diuretic, the dose of diuretic should be reduced before the initiation of enalapril. - To reduce the likelihood of hypotension, the diuretic should be discontinued 2 to 3 days prior to beginning therapy with enalapril. If blood pressure is not controlled with enalapril alone, diuretic therapy should be resumed. - If diuretic therapy cannot be discontinued, an initial dose of 2.5 mg (oral) or 0.625 mg (IV) should be used with careful medical supervision for several hours and until blood pressure has stabilized.

Precautions

BOXED WARNINGS : - If pregnancy is detected, enalapril should be discontinued as soon as possible. - Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.

Safety and effectiveness have not been established in neonates or in pediatric patients with CrCl less than 30 mL/min.

Consult WARNINGS section for dosing related precautions.

Dialysis

Enalapril is removed by hemodialysis (20% to 50%) Hemodialysis: 2.5 mg on dialysis days The dosage on nondialysis days should be adjusted according to blood pressure response.

Other Comments

Administration Advice : - May be taken without regard to meals. - Generally, the use of IV enalapril is not recommended for more than 7 days.

General : - In patients who are currently being treated with a diuretic, symptomatic hypotension occasionally may occur following the initial dose of enalapril. - Compared with Caucasian patients, Black patients have a reduced blood pressure response to monotherapy with angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers; however, the reduced response is largely eliminated if combination therapy that includes an adequate dose of a diuretic is instituted. - Following first time MI, all ACE inhibitors, at comparable appropriate dosages, appear to be equally effective for reducing mortality and recurrent MI rates.

Monitoring : - Hepatic: Liver function tests should be monitored during enalapril therapy. It is recommended to discontinue enalapril and initiate appropriate treatment in patients who develop jaundice and/or experience a marked increase in hepatic enzymes.

More about enalapril

Crixivan (Indinavir) Medical Facts From, Cirixivan

Crixivan

What is Crixivan (indinavir)?

Indinavir is a protease (PRO-tee-ayz) inhibitor antiviral medicine that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

Indinavir is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Indinavir is not a cure for HIV or AIDS.

Indinavir may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Crixivan (indinavir)?

Life-threatening side effects may occur if you take indinavir with certain other medicines. Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with indinavir, and some drugs should not be used together.

What should I discuss with my healthcare provider before taking Crixivan (indinavir)?

You should not use indinavir if you are allergic to it.

Some medicines can cause dangerous or life-threatening side effects when used with indinavir. Your doctor may need to change your treatment plan if you use any of the following drugs:

amiodarone (Cordarone, Pacerone);

rifampin (Rifadin, Rifamate, Rifater, Rimactane);

alprazolam (Xanax), oral midazolam (Versed), or triazolam (Halcion);

atorvastatin (Lipitor), lovastatin (Mevacor, Altoprev, Advicor), rosuvastatin (Crestor), or simvastatin (Zocor, Simcor, Vytorin, Juvisync);

dihydroergotamine (D. H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), ergotamine (Ergomar, Migergot, Wigraine), or methylergonovine (Methergine);

sildenafil (Revatio, for treating pulmonary arterial hypertension); or

sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra) for erectile dysfunction.

To make sure indinavir is safe for you, tell your doctor if you have:

cirrhosis or other liver disease;

kidney disease, or a history of kidney stones;

a bleeding disorder such as hemophilia; or

high cholesterol or triglycerides.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

Your name may need to be listed on an antiviral pregnancy registry when you start using this medication.

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

How should I take Crixivan (indinavir)?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Indinavir should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.

Indinavir is usually taken every 8 hours around the clock. Take the medicine at the same time each day.

Take indinavir with a full glass (8 ounces) of water or skim milk. You may also drink juice, coffee, or tea with this medicine. Drink at least 6 glasses of water each day to prevent kidney stones while you are taking indinavir.

If you prefer to take the medicine with food, eat only a light meal, such as dry toast with jelly, or corn flakes with skim milk and sugar. Avoid eating a high-fat meal.

Use indinavir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

While using indinavir, you will need frequent blood tests.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the capsules in their original container, along with the packet or canister of moisture-absorbing preservative. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If you are more than 2 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Symptoms of an indinavir overdose may include nausea, vomiting, diarrhea, lower back pain, and blood in your urine.

What should I avoid while taking Crixivan (indinavir)?

If you also take didanosine, take it 1 hour before or after you take indinavir, on an empty stomach.

Taking indinavir will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Crixivan (indinavir) side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Indinavir may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with indinavir. Tell your doctor if you have:

signs of a new infection--fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss;

chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;

cold sores, sores on your genital or anal area;

rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;

trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or

swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.

Call your doctor at once if you have:

pain in your side or lower back, blood in your urine;

painful or difficult urination;

blood cell disorders--pale or yellowed skin, fever, easy bruising or bleeding (nosebleeds, bleeding gums), confusion or weakness;

high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss;

liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

(if you also use a "statin" cholesterol medicine)--unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Common side effects may include:

stomach pain, nausea, vomiting, diarrhea;

changes in appetite;

The Ketogenic Diet - Guides And Tips To Success, Keto-Cure

Posted in Keto Diet Information, Written by Craig

One of the most common reasons people start a ketogenic diet or simply cut carbohydrates is to lose weight. But does the hard, scientific evidence say? Additionally, does a low-carb diet just get rid of the water weight - or does it shed body fat and maintain lean mass? In this piece we analyze if eating more fat really makes you less fat. The Key Figures in Body Weight Everyone is always talking about “losing weight”- but what are the exactly referring to? Human body weight refers to the.

Posted in Ketogenic Diet, Written by Craig

In this month's Keto Delivered box, I wanted to bring some new items that I dug up while searching for small companies across the US. Some were given to my by awesome customers (you get a 20% off coupon code when you do and the item is used!), and some were found scavanging forums and farmer's markets asking for different ideas from different people. As always we're bringing you a couple of snacks for your emergency snack "fund" and a few new items to cook with (of course)! I was really.

Posted in Ketogenic Diet, Written by Craig

In this month's Keto Delivered box, I wanted to bring together some flavors that would go together well with a Valentine's day theme. I thought that chocolate and spice would be perfectly paired when you think of foods that you may have on the special day. I wanted to make sure that all of the larger items would last a long time and would keep fueling recipes from February until the March box was sent out. Alongside the larger items, there were a few smaller items for snacking and taking with.

Posted in Ketogenic Diet, Written by Craig

This month in Keto Delivered, I really wanted to put some items in your shelves that you may not be aware of or might not buy on your own. The main items are things that can elevate almost any dish to another level without being hard to use. Alongside those items, we have a few take-a-long snacks that are perfect for long trips, outdoor adventures, or just taking with you for an emergency in a tight situation. There's some awesome companies that I worked with this month, so let's jump right.

Posted in Ketogenic Diet, Written by Craig

Thanksgiving is now over (I hope you guys had a great one, by the way!) and most everyone has received their Keto Delivered box. I've been really excited to see all of the positive feedback and the huge amount of anticipation for the December box to become available. With the holiday season in full effect, I thought that most people would be doing traveling in some sort of way: either by air or road. I wanted to make this Keto Delivered box something that will facilitate the holiday travels.

Posted in Ketogenic Diet, Written by Craig

Thanksgiving is almost here and people are worried that they have to break their ketogenic diet to be able to enjoy the holidays. I'm here to tell you that you don't have to. There's so many delicious keto-friendly foods out there, that both you and your family can enjoy during this holiday. Below are some ideas that I have for Thanksgiving: personal favorites of mine that I'll be serving myself, and some of my favorite recipes that would be a great treat for anyone to serve during a family.

Posted in Keto Diet Information, Written by Craig

Science shows that the ketogenic diet is an effective way to lower blood sugar in diabetes, control insulin resistance, and optimize cholesterol. One of the most common questions we get from people is how to utilize supplements to further reap the benefits of a carbohydrate-restricted diet. Below we outline some science-backed supplements and reasons you might want to use them in order to optimize your carbohydrate-restricted diet. About 145 million Americans use nutritional supplements each.

Posted in Ketogenic Diet, Written by Craig

This month for Keto Delivered, I really wanted to revamp the traditional keto condiment shelf. What do you usually find yourself reaching out for in the fridge when you need a little bit of sauce on top of your burger, eggs, or chicken? You might be a lover of ranch, reduced sugar ketchup, mayonnaise, sriracha, or good ol' hot sauce. For me, it's always mayo or hot sauce (or a mixture of the two). I wanted to take my two favorites and share them with you - in elevated style. Alongside that.

Posted in Keto Diet Information, Written by Craig

We recently touched on how you can use the ketogenic diet to control symptoms of diabetes such as elevated glucose and triglycerides. In this article, we examine research showing the impact that the ketogenic diet has on levels of the hormone insulin, a key regulator of blood sugar in the body. What is Insulin’s Role in the Body? Before we look at the research, we need to know our main players. Insulin is a protein-based hormone produced by beta-cells located in the pancreas. The pancreas.

Posted in Ketogenic Diet, Written by Craig

Fall is here! The leaves are slowly turning orange and the weather is becoming cooler each day that passes by. Pumpkins are popping up in the farmers market, and pumpkin spice. everything is making a return. I say that like it's a bad thing, but I really do love the deep flavors that come out with pumpkin spice - and even better, I'm bringing them to you keto style. I know many of you saw that the first month of Keto Delivered had its setbacks, but month two went much more smoothly - and.

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