Fludarabine - Side Effects, Dosage, Interactions, Fludara


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Fludarabine

Fludarabine is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Fludarabine is used to treat B-cell chronic lymphocytic leukemia (CLL).

Fludarabine is usually given after other cancer medications have been tried without successful response to treatment.

Fludarabine may also be used for purposes not listed in this medication guide.

You should not receive fludarabine if you are also being treated with a cancer medicine called pentostatin (Nipent).

Fludarabine can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

You should not use this medication if you are allergic to fludarabine, or if you are also being treated with a cancer medicine called pentostatin (Nipent).

To make sure you can safely take fludarabine, tell your doctor if you have any of these other conditions:

kidney disease;

bone marrow problems or a weak immune system;

any active infection;

a history of skin cancer; or

a history of a viral infection such as herpes zoster (shingles), Epstein-Barr, or a virus affecting the central nervous system.

Do not use fludarabine if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are receiving fludarabine, whether you are a man or a woman. Keep using birth control for at least 6 months after your treatment ends. Fludarabine use by either parent may cause birth defects.

It is not known whether fludarabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving fludarabine.

Fludarabine Side Effects