Regulacid Indication, Action Of Regulacid, Interactions, Regulacid

Regulacid [in more detail]

Regulacid Mechanism Of Action:

Regulacid is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H + /K + - ATPase in the gastric parietal cell. By acting specifically on the proton pump, omeprazole blocks the final step in acid production, thus reducing gastric acidity.

Regulacid Drug Interactions:

Alprazolam Regulacid increases the effect of benzodiazepine Diazepam Regulacid increases the effect of benzodiazepine Clonazepam Regulacid increases the effect of benzodiazepine Clorazepate Regulacid increases the effect of benzodiazepine Chlordiazepoxide Regulacid increases the effect of benzodiazepine Estazolam Regulacid increases the effect of benzodiazepine Flurazepam Regulacid increases the effect of benzodiazepine Halazepam Regulacid increases the effect of benzodiazepine Ketazolam Regulacid increases the effect of benzodiazepine Midazolam Regulacid increases the effect of benzodiazepine Prazepam Regulacid increases the effect of benzodiazepine Quazepam Regulacid increases the effect of benzodiazepine Triazolam Regulacid increases the effect of benzodiazepine Mephenytoin Regulacid increases the effect of hydantoin Phenytoin Regulacid increases the effect of hydantoin Fosphenytoin Regulacid increases the effect of hydantoin Ethotoin Regulacid increases the effect of hydantoin Voriconazole Voriconazole increases the effect and toxicity of omeprazole St. John's Wort St. John's Wort decreases the levels/effects of omeprazole Methotrexate Regulacid increases the levels of methotrexate Cilostazol Regulacid increases the effect of cilostazol Atazanavir This gastric pH modifier decreases the levels/effects of atazanavir Cyclosporine Regulacid increases the effect and toxicity of cyclosporine Dasatinib Possible decreased levels of dasatinib Enoxacin The agent decreases the absorption of enoxacin Indinavir Regulacid decreases the absorption of indinavir Itraconazole The proton pump inhibitor decreases the absorption of the imidazole Ketoconazole The proton pump inhibitor decreases the absorption of the imidazole Disopyramide The beta-blocker increases toxicity of disopyramide

Food Interactions:

Avoid alcohol. Take 30-60 minutes before meals.

Regulacid Chemical Formula:

Medicine Guides Closure, Clarexid

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Payor Solutions, Imidex

Payor Solutions

The Federal Bureau of Investigation estimates healthcare fraud in the range of 3 to 10 percent of all healthcare expenditures [1]. Or, put in US dollar terms, it is somewhere between $75 billion and an eye-popping $250 billion per year. To add to that, this does not include the softer forms of medical abuse: over-utilization of ineffective treatment plans and general malingering. Combine this with an extremely complicated medical system, containing over 17,000 different diagnoses and over 23,000 different procedures, the question is: How does a claims adjuster decide where to focus their interventions to more effectively reduce leakage? And, where does one streamline the processing of medical bills to increase efficiencies and improve the claimant’s experience?

IMIDEX provides Big Data driven medical analytics to more accurately and objectively stratify a claims adjuster’s caseload across a continuum: from usual and customary treatment; to overbilling; to excessive services; to unnecessary services; and to fraud with runners, kickbacks and fraud rings.

We provide solutions to Workers Compensation, Auto insurance, and Health insurance carriers to more objectively and effectively manage claims. We enable a claims organization to quickly identify claims to fast pay, while at the same time identify cases where active intervention is needed by the adjuster, special investigator, independent medical examiner, or other health care provider. This creates efficiencies in the claims handling process by targeting resources towards the most critical areas where leakage occurs.

[1] Federal Bureau of Investigation, Financial Crimes Report to the Public . Fiscal Year 2010-2011.

Licopeno Medlineplus Suplementos, Lacopen

Licopeno

¿Que es?

El licopeno es una sustancia quimica que existe en forma natural y que es la responsable del color rojo de las frutas y verduras. Es uno de los tantos pigmentos llamados carotenoides. El licopeno se encuentra en las sandias, los pomelos rosas, los albaricoques (damascos) y las guayabas. Se encuentra en cantidades especialmente elevadas en los tomates y los productos de tomates. En America del Norte, el 85% del licopeno en la dieta proviene de los productos de tomate tales como el jugo o concentrado de tomate. Una taza (240 ml) de jugo de tomate proporciona alrededor de 23 mg de licopeno. El procesar los tomates crudos usando el calor (en la elaboracion de jugo de tomate, concentrado de tomate o ketchup por ejemplo), cambia el licopeno a una forma que es mas facil de usar por el cuerpo. El licopeno en los suplementos es tan facil de usar por el cuerpo como el licopeno que se encuentra en los alimentos.

La gente toma licopeno para prevenir las enfermedades cardiacas, para el “endurecimiento de las arterias” (arterioesclerosis) y para el cancer de prostata, de mamas, del pulmon, de la vejiga, de los ovarios, del colon y del pancreas. El licopeno tambien se usa para el tratamiento de la infeccion con el virus del papilloma humano (VPH), que produce la mayoria de los casos de cancer uterino. Algunas personas tambien usan el licopeno para las cataratas y el asma.

¿Qué tan efectivo es?

Natural Medicines Comprehensive Database (La Base Exhaustiva de Datos de Medicamentos Naturales) clasifica la eficacia, basada en evidencia cientifica, de acuerdo a la siguiente escala: Eficaz, Probablemente Eficaz, Posiblemente Eficaz, Posiblemente Ineficaz, Probablemente Ineficaz, Ineficaz, e Insuficiente Evidencia para Hacer una Determinación.

La clasificación de la eficacia para este producto es la siguiente:

Posiblemente ineficaz para.

Cancer de vejiga . La investigacion sugiere que no existe vinculo entre el consumo de licopeno en la dieta y los niveles de licopeno en la sangre y el riego de desarrollar cancer de vejiga.

Diabetes . La investigacion sugiere que una mayor ingesta de licopeno en la dieta no reduce el riesgo de desarrollar diabetes.

Insuficiente evidencia para hacer una determinación para.

Enfermedad ocular relacionada con la edad (maculopatia relacionada con la edad) . Es inconsistente la investigacion sobre la efectividad del licopeno en la enfermedad ocular relacionada con la edad. Cierta evidencia sugiere que las personas con bajos niveles de licopeno son casis dos veces mas propensas a desarrollar enfermedad ocular relacionada con la edad en comparacion con personas con altos niveles de licopeno. Sin embargo, otra investigacion sugiere que no existe vinculo entre los niveles de licopeno o la ingesta de licopeno y el riesgo de sufrir enfermedad ocular relacionada con la edad.

Asma . Es contradictoria la investigacion sobre los efectos del licopeno en personas con asma. La ingesta de licopeno no parece reducir los sintomas del asma en adultos con los sintomas del asma estabilizados. Sin embargo, en personas con antecedentes de asma, provocado por el ejercicio fisico, la ingesta de un producto a base de licopeno (LycoMato, LycoRed Corp. Orange, NJ) parece mejorar la funcion pulmonar despues del ejercicio fisico.

Endurecimiento de las arterias (ateroesclerosis) . Existe cierta evidencia que muestra que los altos niveles de licopeno en sangre estan asociados a un menor riesgo de endurecimiento de las arterias. Existe cierta evidencia que muestra que los altos niveles de licopeno en sangre pueden disminuir la cardiopatia asociada con el endureciendo de las arterias. Sin embargo, no parece haber un vinculo entre los niveles de licopeno y el riesgo de sufrir un ACV.

Agrandamiento de prostata (Hiperplasia prostatica benigna, HPB) . La investigacion preliminar muestra que la ingesta de licopeno puede disminuir el progreso del agrandamiento de la prostata y puede mejorar los sintomas en personas con esta condicion. Sin embargo, otra investigacion descubrio que no existe un vinculo entre la ingesta de licopeno y el agrandamiento de la prostata.

Cancer de mama . Es contradictoria la investigacion sobre la manera en que el licopeno podria causar cancer de mama. Existe cierta evidencia que sugiere que los altos niveles de licopeno en sangre estan asociados a un menor riesgo de sufrir cancer de mama. Sin embargo, otra investigacion muestra que ni la ingesta de licopeno ni los niveles de licopeno en sangre estan vinculados al riesgo de sufrir cancer de mama.

Cardiopatia . Cierta evidencia muestra que las mujeres con altos niveles de luteina en la sangre presentan un menor riesgo de desarrollar cardiopatia. Sin embargo, otra investigacion muestra que no existe vinculo entre la ingesta de licopeno y la cardiopatia o el ACV en las mujeres. Ademas, una mayor ingesta de licopeno no parece prevenir los infartos de miocardio en hombres con menor riesgo de sufrir cardiopatia.

Cataratas . Un estudio sugiere que los altos niveles de licopeno en sangre estan asociados con un menor riesgo de desarrollar cataratas. Sin embargo, otros estudios no han descubierto ningun vinculo entre la ingesta de licopeno o los altos niveles de licopeno y el riesgo de desarrollar cataratas.

Cancer de cuello de utero . Es contradictoria la investigacion sobre la manera en que el licopeno podria causar cancer de cuello de utero. Existe cierta evidencia que sugiere que los altos niveles de licopeno en sangre o una gran ingesta de licopeno estan asociados con un menor riesgo de sufrir cancer de cuello de utero. No obstante, en otros estudios no se ha descubierto tal vinculo.

Cancer colorrectal . Es contradictoria la investigacion sobre la manera en que el licopeno podria causar cancer de cuello de utero. Cierta evidencia sugiere que las personas que ingieren una alta cantidad de licopeno son menos propensos a desarrollar cancer colorrectal que aquellas que ingieren menos licopeno. Sin embargo, otra investigacion muestra que no existe un vinculo entre la ingesta de licopeno y el riesgo de sufrir de cancer colorrectal.

Gingivitis . La investigacion preliminar muestra qye la ingesta de un suplemento especifico con licopeno (LycoRed, Jagsonpal Pharmaceuticals) durante dos semanas o una unica inyeccion de licopeno en gel en las envias reduce la gingivitis.

Tumor cerebral (glioma) . La investigacion preliminar muestra que la ingesta de licopeno durante tres meses no mejora la respuesta a la radioterapia y la quimioterapia en personas con tumores cerebrales.

Ulceras causadas por infeccion por Helicobacter pylori . La investigacion preliminar muestra que la ingesta de licopeno junto con antibioticos no ayuda en el tratamiento de la infeccion por Helicobacter pylori en comparacion con la ingesta solo de antibioticos.

Infeccion por virus del papiloma humano (VPH) . Las mujeres con altos niveles de licopeno en la sangre parecen recuperarse de la infeccion por VPH asociada con cancer mas rapidamente que aquellas con bajos niveles de licopeno en la sangre.

Colesterol alto . La investigacion preliminar muestra que la ingesta de un suplemento especifico con licopeno (LycoRed, Jagsonpal Pharmaceuticals) durante seis meses disminuye el colesterol de lipoproteina (LDL o “malo”) de baja densidad y aumenta el colesterol de lipoproteina de alta densidad (HDL o “bueno”). Sin embargo, otra evidencia sugiere que el licopeno no afecta los niveles de colesterol en adultos sanos o en aquellos con cardiopatia.

Hipertension arterial . La investigacion preliminar muestra que la ingesta diaria de un producto especifico (LycoMato, LycoRed Corp. Organge, NJ) durante ocho semanas disminuye la presion arterail alta en personas con hipertension arterial. Sin embargo, otra investigacion sugiere que no existe vinculo entre los niveles de licopeno en sangre y el riesgo de desarrollar hipertension arterial.

Cancer de pulmon . Es contradictoria la investigacion sobre la manera en que el licopeno podria causar cancer de pulmon. Cierta investigacion muestra que incorporar poco licopeno en la dieta esta vinculado con un mayor riesgo de sufrir cancer de pulmon. Sin embargo, otra investigacion sugiere que no existe un vinculo entre el consumo de licopeno o los niveles de licopeno en la sangre y el riego de desarrollar cancer de pulmon.

Problemas de infertilidad masculina . La investigacion preliminar muestra que la ingesta diaria de licopeno durante tres meses mejora la calidad del espermatozoide en algunos hombres con problemas de fertilidad debido a causas desconocidas.

Sintomas menopausicos . La investigacion preliminar muestra que la ingesta diaria de un producto especifico con licopeno, calcio, vitamina D3, astaxantina y bioflavonoides de los citricos (Cor. Con. International, Parma, Italy) durante ocho semanas reduce los sintomas menopausicos incluidos sofocos, dolor articular, ansiedad y depresion.

Lesiones precancerosas de color blanco en la boca (leucoplasia oral) . La investigacion preliminar muestra que la ingesta de un suplemento de licopeno especifico (LycoRed, Jagsonpal Pharmaceutical) dos veces por dia mejora las lesiones precancerosas de color blanco en la boca.

Ulceras e inflamacion en la boca (mucositis oral) . La investigacion preliminar muestra que la ingesta de licopeno durante dos meses mejora las ulceraciones en la boca en personas con mucositis oral.

Cancer de ovario . Es contradictoria la evidencia sobre la efectividad del licopeno para tratar el cancer de ovario. Cierta investigacion muestra que una dieta rica en carotenoides, incluido el licopeno, parece ayudar a prevenir el cancer de ovario en mujeres jovenes (menopausicas). Sin embargo, otra investigacion muestra que el riesgo de desarrollar cancer de ovario no esta vinculado a los niveles de licopeno en la sangre.

Cancer de pancreas . Cierta investigacion preliminar muestra que una dieta alta en licopeno, principalmente del tomate, parece disminuir el riesgo de desarrollar cancer de pancreas.

Hipertension arterial durante el embarazo . No es clara la investigacion sobre el efecto del licopeno para prevenir la presion arterial alta durante el embarazo. Cierta investigacion muestra que la ingesta de un suplemento de licopeno especifico (LycoRed, Jagonpal Pharmaceuticals) dos veces por dia, comenzando entre las semanas 16 y 20 del embarazo y continuando hasta el parto, disminuye tanto la presion arterial alta como las complicaciones asociadas. Sin embargo, otra investigacion sugiere que el licopeno no afecta la presion arterial durante el embarazo.

Cancer de prostata . Es contradictoria la investigacion sobre los efectos del licopeno para prevenir o tratar el cancer de prostata. Existe cierta investigacion que sugiere que una mayor ingesta de licopeno o los altos niveles de licopeno en sangre estan asociados con un menor riesgo de desarrollar cancer de prostata. Sin embargo, otra investigacion muestra que no existe vinculo entre la ingesta de licopeno o los altos niveles de licopeno en la sangre y el riesgo de sufrir de cancer de prostata. Ademas, la investigacion preliminar llevada cabo en los hombres que sufren cambios precancerosos en la prostata muestra que la ingesta de 4 mg de suplementos de licopeno dos veces al dia podria retardar o prevenir el avance del cancer de prostata. Sin embargo, en otra investigacion, la ingesta diaria de licopeno durante un maximo de un ano no parecio ayudar a tratar el cancer de prostata.

Inflamacion de la prostata y dolor pelvico . La investigacion preliminar muestra que la ingesta de una combinacion especifica de licopeno, selenio y palma enana (Profluss, KonPharma) durante ocho semanas reduce el dolor en los hombres con inflamacion de la prostata y dolor pelvico en comparacion con la ingesta solo de palma enana.

Cancer de rinon (carcinoma de celulas renales) . La investigacion muestra que no existe vinculo entre el consume de licopeno y el riesgo de desarrollar cancer de rinon.

Quemaduras solares . La investigacion preliminar muestra que la ingesta de licopeno, solo o junto con otros ingredientes, podria proteger contra quemaduras solares.

Otras afecciones .

Se necesita mas evidencia para poder aprobar el licopeno para estos usos.

¿Como funciona?

El licopeno es un poderoso antioxidante que puede ayudar a proteger a las celulas para que estas no sufran dano. Por esta razon hay un gran interes en investigar el rol del licopeno, si es que juega uno, en la prevencion del cancer.

¿Hay preocupacion por la seguridad de su uso?

El licopeno es PROBABLEMENTE SEGURO cuando se lo ingiere en cantidades apropiadas. Suplementos diarios que contienen hasta 120 mg de licopeno se han usado sin peligro hasta durante un ano.

Advertencias y precauciones especiales:

Embarazo y lactancia . El licopeno ES PROBABLEMENTE durante el embarazo y la lactancia cuando se lo ingieren en cantidades comunmente presentes en los alimentos. Sin embargo, el licopeno es POSIBLEMENTE SEGURO cuando se lo ingiere como suplemento durante el embarazo. En un estudio donde se uso un suplemento de licopeno (LycoRed, Jagsonpal Pharmaceuticals), se descubrio que la ingesta de 2 mg por dia, comenzando entre las semanas 12 y 20 del embarazo y continuando hasta el parto, aumento la tasa de nacimientos prematuros y de bebes con bajo peso al nacer. Existe poca informacion sobre si los suplementos de licopeno son seguro s durante la lactancia. Si esta embarazada o amantando, evite el uso del licopeno en cantidades mayores de las que se encuentra en los alimentos.

Cancer de prostata . Investigaciones en desarrollo sugieren que el licopeno podria empeorar el cancer de prostata ya presente. Hasta que no se tenga mas informacion, evite tomar licopeno si ha sido diagnosticado con cancer de prostata.

¿Existen interacciones con medicamentos?

No se sabe si este producto interactúa con algún medicamento.

Si está tomando medicamentos, converse con su proveedor de atención médica antes de empezar a tomar este producto.

¿Existen interacciones con hierbas y suplementos?

Betacaroteno El tomar betacaroteno junto con licopeno podria aumentar la cantidad de licopeno que es absorbida por el cuerpo.

¿Existen interacciones con alimentos?

OLESTRA (sustituto de la grasa) La ingesta de olestra podria reducir la cantidad de licopeno absorbida por el cuerpo.

¿Que dosis se utiliza?

La dosis apropiada del licopeno depende de muchos factores tales como la edad de la persona, el estado de salud y varias otras condiciones. En este momento no hay suficiente informacion cientifica para determinar un rango de dosis apropiado para el uso del licopeno. Tenga en mente que los productos naturales no son siempre necesariamente seguros y las dosis pueden ser importantes. Asegurese de seguir las instrucciones en las etiquetas de los productos y consulte con su farmaceutico, doctor u otro proveedor de salud medica antes de usarlos.

Otros nombres

Referencias

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Catalano, A. Simone, R. E. Cittadini, A. Reynaud, E. Caris-Veyrat, C. and Palozza, P. Comparative antioxidant effects of lycopene, apo-10'-lycopenoic acid and apo-14'-lycopenoic acid in human macrophages exposed to H2O2 and cigarette smoke extract. Food Chem Toxicol. 2013;51:71-79. View abstract .

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Chandra, R. V. Sandhya, Y. P. Nagarajan, S. Reddy, B. H. Naveen, A. and Murthy, K. R. Efficacy of lycopene as a locally delivered gel in the treatment of chronic periodontitis: smokers vs nonsmokers. Quintessence. Int 2012;43:401-411. View abstract .

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Chole, R. H. Gondivkar, S. M. Gadbail, A. R. Balsaraf, S. Chaudhary, S. Dhore, S. V. Ghonmode, S. Balwani, S. Mankar, M. Tiwari, M. and Parikh, R. V. Review of drug treatment of oral submucous fibrosis. Oral Oncol 2012;48:393-398. View abstract .

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Riccioni, G. Scotti, L. Di, Ilio E. Bucciarelli, V. Ballone, E. De, Girolamo M. D' Orazio, N. Martini, F. Aceto, A. and Bucciarelli, T. Lycopene and preclinical carotid atherosclerosis. J. Biol. Regul. Homeost. Agents 2011;25:435-441. View abstract .

Ferris-Tortajada, J. Berbel-Tornero, O. Garcia-Castell, J. Ortega-Garcia, J. A. and Lopez-Andreu, J. A. [Dietetic factors associated with prostate cancer: protective effects of Mediterranean diet]. Actas Urol. Esp. 2012;36:239-245. View abstract .

Magbanua, M. J. Roy, R. Sosa, E. V. Weinberg, V. Federman, S. Mattie, M. D. Hughes-Fulford, M. Simko, J. Shinohara, K. Haqq, C. M. Carroll, P. R. and Chan, J. M. Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation. PLoS. One. 2011;6:e24004. View abstract .

Richelle, M. Lambelet, P. Rytz, A. Tavazzi, I. Mermoud, A. F. Juhel, C. Borel, P. and Bortlik, K. The proportion of lycopene isomers in human plasma is modulated by lycopene isomer profile in the meal but not by lycopene preparation. Br J Nutr 2012;107:1482-1488. View abstract .

Garcia-Alonso, F. J. Jorge-Vidal, V. Ros, G. and Periago, M. J. Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women. Eur. J Nutr 2012;51:415-424. View abstract .

van Breemen, R. B. Sharifi, R. Viana, M. Pajkovic, N. Zhu, D. Yuan, L. Yang, Y. Bowen, P. E. and Stacewicz-Sapuntzakis, M. Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. Cancer Prev. Res.(Phila) 2011;4:711-718. View abstract .

Kristal, A. R. Till, C. Platz, E. A. Song, X. King, I. B. Neuhouser, M. L. Ambrosone, C. B. and Thompson, I. M. Serum lycopene concentration and prostate cancer risk: results from the Prostate Cancer Prevention Trial. Cancer Epidemiol. Biomarkers Prev. 2011;20:638-646. View abstract .

McClean, C. M. Clegg, M. Shafat, A. Murphy, M. H. Trinick, T. Duly, E. McLaughlin, J. Fogarty, M. and Davison, G. W. The impact of acute moderate intensity exercise on arterial regional stiffness, lipid peroxidation, and antioxidant status in healthy males. Res. Sports Med. 2011;19:1-13. View abstract .

Kim, J. Y. Paik, J. K. Kim, O. Y. Park, H. W. Lee, J. H. Jang, Y. and Lee, J. H. Effects of lycopene supplementation on oxidative stress and markers of endothelial function in healthy men. Atherosclerosis 2011;215:189-195. View abstract .

Ried, K. and Fakler, P. Protective effect of lycopene on serum cholesterol and blood pressure: Meta-analyses of intervention trials. Maturitas 2011;68:299-310. View abstract .

Chan, J. M. Weinberg, V. Magbanua, M. J. Sosa, E. Simko, J. Shinohara, K. Federman, S. Mattie, M. Hughes-Fulford, M. Haqq, C. and Carroll, P. R. Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer. Cancer Causes Control 2011;22:141-150. View abstract .

Rizwan, M. Rodriguez-Blanco, I. Harbottle, A. Birch-Machin, M. A. Watson, R. E. and Rhodes, L. E. Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. Br. J.Dermatol. 2011;164:154-162. View abstract .

Zhang, X. Wang, Q. Neil, B. and Chen, X. Effect of lycopene on androgen receptor and prostate-specific antigen velocity. Chin Med. J.(Engl.) 2010;123:2231-2236. View abstract .

Stangl, V. Kuhn, C. Hentschel, S. Jochmann, N. Jacob, C. Bohm, V. Frohlich, K. Muller, L. Gericke, C. and Lorenz, M. Lack of effects of tomato products on endothelial function in human subjects: results of a randomised, placebo-controlled cross-over study. Br. J.Nutr. 2011;105:263-267. View abstract .

Kristal, A. R. Arnold, K. B. Neuhouser, M. L. Goodman, P. Platz, E. A. Albanes, D. and Thompson, I. M. Diet, supplement use, and prostate cancer risk: results from the prostate cancer prevention trial. Am. J.Epidemiol. 9-1-2010;172:566-577. View abstract .

Beilby, J. Ambrosini, G. L. Rossi, E. de Klerk, N. H. and Musk, A. W. Serum levels of folate, lycopene, beta-carotene, retinol and vitamin E and prostate cancer risk. Eur. J.Clin. Nutr. 2010;64:1235-1238. View abstract .

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Mackinnon, E. S. Rao, A. V. Josse, R. G. and Rao, L. G. Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women. Osteoporos. Int. 2011;22:1091-1101. View abstract .

Chai, W. Conroy, S. M. Maskarinec, G. Franke, A. A. Pagano, I. S. and Cooney, R. V. Associations between obesity and serum lipid-soluble micronutrients among premenopausal women. Nutr. Res. 2010;30:227-232. View abstract .

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Talvas, J. Caris-Veyrat, C. Guy, L. Rambeau, M. Lyan, B. Minet-Quinard, R. Lobaccaro, J. M. Vasson, M. P. George, S. Mazur, A. and Rock, E. Differential effects of lycopene consumed in tomato paste and lycopene in the form of a purified extract on target genes of cancer prostatic cells. Am. J.Clin. Nutr. 2010;91:1716-1724. View abstract .

Morgia, G. Mucciardi, G. Gali, A. Madonia, M. Marchese, F. Di, Benedetto A. Romano, G. Bonvissuto, G. Castelli, T. Macchione, L. and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study. Urol. Int. 2010;84:400-406. View abstract .

Puri, T. Goyal, S. Julka, P. K. Nair, O. Sharma, D. N. and Rath, G. K. Lycopene in treatment of high-grade gliomas: a pilot study. Neurol. India 2010;58:20-23. View abstract .

Richelle, M. Sanchez, B. Tavazzi, I. Lambelet, P. Bortlik, K. and Williamson, G. Lycopene isomerisation takes place within enterocytes during absorption in human subjects. Br. J.Nutr. 2010;103:1800-1807. View abstract .

VanEenwyk, J. Davis, F. G. and Bowen, P. E. Dietary and serum carotenoids and cervical intraepithelial neoplasia. Int J Cancer 4-22-1991;48:34-38. View abstract .

Harris, R. W. Key, T. J. Silcocks, P. B. Bull, D. and Wald, N. J. A case-control study of dietary carotene in men with lung cancer and in men with other epithelial cancers. Nutr Cancer 1991;15:63-68. View abstract .

Darvin, M. E. Haag, S. F. Meinke, M. C. Sterry, W. and Lademann, J. Determination of the influence of IR radiation on the antioxidative network of the human skin. J. Biophotonics. 2011;4(1-2):21-29. View abstract .

Darvin, M. E. Haag, S. Meinke, M. Zastrow, L. Sterry, W. and Lademann, J. Radical production by infrared A irradiation in human tissue. Skin Pharmacol. Physiol 2010;23:40-46. View abstract .

Markovits, N. Ben, Amotz A. and Levy, Y. The effect of tomato-derived lycopene on low carotenoids and enhanced systemic inflammation and oxidation in severe obesity. Isr. Med. Assoc. J. 2009;11:598-601. View abstract .

Le Marchand, L. Hankin, J. H. Kolonel, L. N. and Wilkens, L. R. Vegetable and fruit consumption in relation to prostate cancer risk in Hawaii: a reevaluation of the effect of dietary beta-carotene. Am J Epidemiol. 2-1-1991;133:215-219. View abstract .

Haseen, F. Cantwell, M. M. O'Sullivan, J. M. and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic. Dis. 2009;12:325-332. View abstract .

Franceschi, S. Bidoli, E. Baron, A. E. Barra, S. Talamini, R. Serraino, D. and La Vecchia, C. Nutrition and cancer of the oral cavity and pharynx in north-east Italy. Int J Cancer 1-2-1991;47:20-25. View abstract .

Ziegler, R. G. Vegetables, fruits, and carotenoids and the risk of cancer. Am J Clin Nutr 1991;53(1 Suppl):251S-259S. View abstract .

Tomita, L. Y. Longatto, Filho A. Costa, M. C. Andreoli, M. A. Villa, L. L. Franco, E. L. and Cardoso, M. A. Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women. Int. J.Cancer 2-1-2010;126:703-714. View abstract .

Cho, H. Kim, M. K. Lee, J. K. Son, S. K. Lee, K. B. Lee, J. M. Lee, J. P. Hur, S. Y. and Kim, J. H. Relationship of serum antioxidant micronutrients and sociodemographic factors to cervical neoplasia: a case-control study. Clin. Chem. Lab Med. 2009;47:1005-1012. View abstract .

Banerjee, S. Jeyaseelan, S. and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J. Obstet. Gynaecol. Res. 2009;35:477-482. View abstract .

Blume-Peytavi, U. Rolland, A. Darvin, M. E. Constable, A. Pineau, I. Voit, C. Zappel, K. Schafer-Hesterberg, G. Meinke, M. Clavez, R. L. Sterry, W. and Lademann, J. Cutaneous lycopene and beta-carotene levels measured by resonance Raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation. Eur. J.Pharm. Biopharm. 2009;73:187-194. View abstract .

Lee, C. Y. Isaac, H. B. Huang, S. H. Long, L. H. Wang, H. Gruber, J. Ong, C. N. Kelly, R. P. and Halliwell, B. Limited antioxidant effect after consumption of a single dose of tomato sauce by young males, despite a rise in plasma lycopene. Free Radic. Res. 2009;43:622-628. View abstract .

Zhang, L. X. Cooney, R. V. and Bertram, J. S. Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis 1991;12:2109-2114. View abstract .

Di Giacomo, C. Acquaviva, R. Sorrenti, V. Vanella, A. Grasso, S. Barcellona, M. L. Galvano, F. Vanella, L. and Renis, M. Oxidative and antioxidant status in plasma of runners: effect of oral supplementation with natural antioxidants. J. Med. Food 2009;12:145-150. View abstract .

Ellinger, S. Ellinger, J. Muller, S. C. and Stehle, P. [Tomatoes and lycopene in prevention and therapy--is there an evidence for prostate diseases?]. Aktuelle Urol. 2009;40:37-43. View abstract .

Hu, J. F. Liu, Y. Y. Yu, Y. K. Zhao, T. Z. Liu, S. D. and Wang, Q. Q. Diet and cancer of the colon and rectum: a case-control study in China. Int J Epidemiol. 1991;20:362-367. View abstract .

Gonzalez, C. A. Sanz, J. M. Marcos, G. Pita, S. Brullet, E. Saigi, E. Badia, A. and Riboli, E. Dietary factors and stomach cancer in Spain: a multi-centre case - control study. Int J Cancer 10-21-1991;49:513-519. View abstract .

Royer, M. Bulai, Livideanu C. Periquet, B. Maybon, P. Lamant, L. Mazereeuw-Hautier, J. Ferrieres, J. and Paul, C. [Orange skin and xanthomas associated with lycopenaemia in a setting of type III dyslipoproteinemia]. Ann. Dermatol. Venereol. 2009;136:42-45. View abstract .

Hozawa, A. Jacobs, D. R. Jr. Steffes, M. W. Gross, M. D. Steffen, L. M. and Lee, D. H. Circulating carotenoid concentrations and incident hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J. Hypertens. 2009;27:237-242. View abstract .

Perabo, F. G. von Low, E. C. Siener, R. Ellinger, J. Muller, S. C. and Bastian, P. J. [A critical assessment of phytotherapy for prostate cancer]. Urologe A 2009;48:270-283. View abstract .

Schwenke, C. Ubrig, B. Thurmann, P. Eggersmann, C. and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J. Urol. 2009;181:1098-1103. View abstract .

Sanchez-Muniz, F. J. Maki, K. C. Schaefer, E. J. and Ordovas, J. M. Serum lipid and antioxidant responses in hypercholesterolemic men and women receiving plant sterol esters vary by apolipoprotein E genotype. J. Nutr. 2009;139:13-19. View abstract .

Paran, E. Novack, V. Engelhard, Y. N. and Hazan-Halevy, I. The effects of natural antioxidants from tomato extract in treated but uncontrolled hypertensive patients. Cardiovasc. Drugs Ther. 2009;23:145-151. View abstract .

Itsiopoulos, C. Hodge, A. and Kaimakamis, M. Can the Mediterranean diet prevent prostate cancer? Mol. Nutr. Food Res. 2009;53:227-239. View abstract .

Knekt, P. Jarvinen, R. Seppanen, R. Rissanen, A. Aromaa, A. Heinonen, O. P. Albanes, D. Heinonen, M. Pukkala, E. and Teppo, L. Dietary antioxidants and the risk of lung cancer. Am J Epidemiol. 9-1-1991;134:471-479. View abstract .

Fedorowicz, Z. Chan Shih-Yen, E. Dorri, M. Nasser, M. Newton, T. and Shi, L. Interventions for the management of oral submucous fibrosis. Cochrane. Database. Syst. Rev. 2008;:CD007156. View abstract .

Riboli, E. Gonzalez, C. A. Lopez-Abente, G. Errezola, M. Izarzugaza, I. Escolar, A. Nebot, M. Hemon, B. and Agudo, A. Diet and bladder cancer in Spain: a multi-centre case-control study. Int J Cancer 9-9-1991;49:214-219. View abstract .

Boeing, H. Jedrychowski, W. Wahrendorf, J. Popiela, T. Tobiasz-Adamczyk, B. and Kulig, A. Dietary risk factors in intestinal and diffuse types of stomach cancer: a multicenter case-control study in Poland. Cancer Causes Control 1991;2:227-233. View abstract .

Devaraj, S. Mathur, S. Basu, A. Aung, H. H. Vasu, V. T. Meyers, S. and Jialal, I. A dose-response study on the effects of purified lycopene supplementation on biomarkers of oxidative stress. J. Am. Coll. Nutr. 2008;27:267-273. View abstract .

Hernandez-Valero, M. A. Thomson, C. A. Hernandez, M. Tran, T. Detry, M. A. Theriault, R. L. Hajek, R. A. Pierce, J. P. Flatt, S. W. Caan, B. J. and Jones, L. A. Comparison of baseline dietary intake of Hispanic and matched non-Hispanic white breast cancer survivors enrolled in the Women's Healthy Eating and Living study. J. Am. Diet. Assoc. 2008;108:1323-1329. View abstract .

Denniss, S. G. Haffner, T. D. Kroetsch, J. T. Davidson, S. R. Rush, J. W. and Hughson, R. L. Effect of short-term lycopene supplementation and postprandial dyslipidemia on plasma antioxidants and biomarkers of endothelial health in young, healthy individuals. Vasc. Health Risk Manag. 2008;4:213-222. View abstract .

Baghurst, P. A. McMichael, A. J. Slavotinek, A. H. Baghurst, K. I. Boyle, P. and Walker, A. M. A case-control study of diet and cancer of the pancreas. Am J Epidemiol. 7-15-1991;134:167-179. View abstract .

Burri, B. J. Chapman, M. H. Neidlinger, T. R. Seo, J. S. and Ishida, B. K. Tangerine tomatoes increase total and tetra-cis-lycopene isomer concentrations more than red tomatoes in healthy adult humans. Int. J.Food Sci. Nutr. 2009;60 Suppl 1:1-16. View abstract .

Voskuil, D. W. Vrieling, A. Korse, C. M. Beijnen, J. H. Bonfrer, J. M. van, Doorn J. Kaas, R. Oldenburg, H. S. Russell, N. S. Rutgers, E. J. Verhoef, S. van Leeuwen, F. E. van't Veer, L. J. and Rookus, M. A. Effects of lycopene on the insulin-like growth factor (IGF) system in premenopausal breast cancer survivors and women at high familial breast cancer risk. Nutr. Cancer 2008;60:342-353. View abstract .

Grainger, E. M. Schwartz, S. J. Wang, S. Unlu, N. Z. Boileau, T. W. Ferketich, A. K. Monk, J. P. Gong, M. C. Bahnson, R. R. DeGroff, V. L. and Clinton, S. K. A combination of tomato and soy products for men with recurring prostate cancer and rising prostate specific antigen. Nutr Cancer 2008;60:145-154. View abstract .

Wood, L. G. Garg, M. L. Powell, H. and Gibson, P. G. Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: proof of concept. Free Radic. Res. 2008;42:94-102. View abstract .

Schnabele, K. Briviba, K. Bub, A. Roser, S. Pool-Zobel, B. L. and Rechkemmer, G. Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans. Br. J.Nutr. 2008;99:606-613. View abstract .

Chandra, R. V. Prabhuji, M. L. Roopa, D. A. Ravirajan, S. and Kishore, H. C. Efficacy of lycopene in the treatment of gingivitis: a randomised, placebo-controlled clinical trial. Oral Health Prev. Dent 2007;5:327-336. View abstract .

Schwarz, S. Obermuller-Jevic, U. C. Hellmis, E. Koch, W. Jacobi, G. and Biesalski, H. K. Lycopene inhibits disease progression in patients with benign prostate hyperplasia. J Nutr 2008;138:49-53. View abstract .

Vaishampayan, U. Hussain, M. Banerjee, M. Seren, S. Sarkar, F. H. Fontana, J. Forman, J. D. Cher, M. L. Powell, I. Pontes, J. E. and Kucuk, O. Lycopene and soy isoflavones in the treatment of prostate cancer. Nutr Cancer 2007;59:1-7. View abstract .

Blum, A. Monir, M. Khazim, K. Peleg, A. and Blum, N. Tomato-rich (Mediterranean) diet does not modify inflammatory markers. Clin. Invest Med. 2007;30:E70-E74. View abstract .

Kawashima, A. Madarame, T. Koike, H. Komatsu, Y. and Wise, J. A. Four week supplementation with mixed fruit and vegetable juice concentrates increased protective serum antioxidants and folate and decreased plasma homocysteine in Japanese subjects. Asia Pac. J.Clin. Nutr. 2007;16:411-421. View abstract .

Schmitz, H. H. Poor, C. L. Wellman, R. B. and Erdman, J. W. Jr. Concentrations of selected carotenoids and vitamin A in human liver, kidney and lung tissue. J Nutr 1991;121:1613-1621. View abstract .

Steinmetz, K. A. and Potter, J. D. Vegetables, fruit, and cancer. II. Mechanisms. Cancer Causes Control 1991;2:427-442. View abstract .

Jacob, K. Periago, M. J. Bohm, V. and Berruezo, G. R. Influence of lycopene and vitamin C from tomato juice on biomarkers of oxidative stress and inflammation. Br. J.Nutr. 2008;99:137-146. View abstract .

Shen, Y. C. Chen, S. L. and Wang, C. K. Contribution of tomato phenolics to antioxidation and down-regulation of blood lipids. J. Agric. Food Chem. 8-8-2007;55:6475-6481. View abstract .

Silaste, M. L. Alfthan, G. Aro, A. Kesaniemi, Y. A. and Horkko, S. Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidation. Br. J.Nutr. 2007;98:1251-1258. View abstract .

Bunker, C. H. McDonald, A. C. Evans, R. W. de la, Rosa N. Boumosleh, J. M. and Patrick, A. L. A randomized trial of lycopene supplementation in Tobago men with high prostate cancer risk. Nutr Cancer 2007;57:130-137. View abstract .

Potischman, N. Herrero, R. Brinton, L. A. Reeves, W. C. Stacewicz-Sapuntzakis, M. Jones, C. J. Brenes, M. M. Tenorio, F. de Britton, R. C. and Gaitan, E. A case-control study of nutrient status and invasive cervical cancer. II. Serologic indicators. Am J Epidemiol. 12-1-1991;134:1347-1355. View abstract .

Goyal, A. Chopra, M. Lwaleed, B. A. Birch, B. and Cooper, A. J. The effects of dietary lycopene supplementation on human seminal plasma. BJU. Int 2007;99:1456-1460. View abstract .

Bose, K. S. and Agrawal, B. K. Effect of lycopene from cooked tomatoes on serum antioxidant enzymes, lipid peroxidation rate and lipid profile in coronary heart disease. Singapore Med. J. 2007;48:415-420. View abstract .

Unlu, N. Z. Bohn, T. Francis, D. M. Nagaraja, H. N. Clinton, S. K. and Schwartz, S. J. Lycopene from heat-induced cis-isomer-rich tomato sauce is more bioavailable than from all-trans-rich tomato sauce in human subjects. Br J Nutr 2007;98:140-146. View abstract .

Jatoi, A. Burch, P. Hillman, D. Vanyo, J. M. Dakhil, S. Nikcevich, D. Rowland, K. Morton, R. Flynn, P. J. Young, C. and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II study from the North Central Cancer Treatment Group. Urology 2007;69:289-294. View abstract .

Bose, K. S. and Agrawal, B. K. Effect of long term supplementation of tomatoes (cooked) on levels of antioxidant enzymes, lipid peroxidation rate, lipid profile and glycated haemoglobin in Type 2 diabetes mellitus. West Indian Med. J. 2006;55:274-278. View abstract .

Unlu, N. Z. Bohn, T. Francis, D. Clinton, S. K. and Schwartz, S. J. Carotenoid absorption in humans consuming tomato sauces obtained from tangerine or high-beta-carotene varieties of tomatoes. J Agric Food Chem 2-21-2007;55:1597-1603. View abstract .

Kumar, A. Bagewadi, A. Keluskar, V. and Singh, M. Efficacy of lycopene in the management of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol. Endod. 2007;103:207-213. View abstract .

Blum, A. Merei, M. Karem, A. Blum, N. Ben-Arzi, S. Wirsansky, I. and Khazim, K. Effects of tomatoes on the lipid profile. Clin. Invest Med. 2006;29:298-300. View abstract .

Bosetti, C. Scotti, L. Maso, L. D. Talamini, R. Montella, M. Negri, E. Ramazzotti, V. Franceschi, S. and La Vecchia, C. Micronutrients and the risk of renal cell cancer: a case-control study from Italy. Int J Cancer 2-15-2007;120:892-896. View abstract .

Paterson, E. Gordon, M. H. Niwat, C. George, T. W. Parr, L. Waroonphan, S. and Lovegrove, J. A. Supplementation with fruit and vegetable soups and beverages increases plasma carotenoid concentrations but does not alter markers of oxidative stress or cardiovascular risk factors. J. Nutr. 2006;136:2849-2855. View abstract .

Barber, N. J. Zhang, X. Zhu, G. Pramanik, R. Barber, J. A. Martin, F. L. Morris, J. D. and Muir, G. H. Lycopene inhibits DNA synthesis in primary prostate epithelial cells in vitro and its administration is associated with a reduced prostate-specific antigen velocity in a phase II clinical study. Prostate Cancer Prostatic. Dis 2006;9:407-413. View abstract .

O'Kennedy, N. Crosbie, L. van, Lieshout M. Broom, J. I. Webb, D. J. and Duttaroy, A. K. Effects of antiplatelet components of tomato extract on platelet function in vitro and ex vivo: a time-course cannulation study in healthy humans. Am. J.Clin. Nutr. 2006;84:570-579. View abstract .

O'Kennedy, N. Crosbie, L. Whelan, S. Luther, V. Horgan, G. Broom, J. I. Webb, D. J. and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am. J.Cl

It S Elemental - The Element Chlorine, Clorin

The Element Chlorine

Density: 0.003214 grams per cubic centimeter

Phase at Room Temperature: Gas

Element Classification: Non-metal

What's in a name? From the Greek word for greenish yellow, chloros .

Say what? Chlorine is pronounced as KLOR-een or as KLOR-in .

Since it combines directly with nearly every element, chlorine is never found free in nature. Chlorine was first produced by Carl Wilhelm Scheele, a Swedish chemist, when he combined the mineral pyrolusite (MnO 2 ) with hydrochloric acid (HCl) in 1774. Although Scheele thought the gas produced in his experiment contained oxygen. Sir Humphry Davy proved in 1810 that it was actually a distinct element. Today, most chlorine is produced through the electrolysis of aqueous sodium chloride (NaCl).

Chlorine is commonly used as an antiseptic and is used to make drinking water safe and to treat swimming pools. Large amounts of chlorine are used in many industrial processes, such as in the production of paper products, plastics, dyes, textiles, medicines, antiseptics, insecticides, solvents and paints.

Two of the most familiar chlorine compounds are sodium chloride (NaCl) and hydrogen chloride (HCl). Sodium chloride, commonly known as table salt, is used to season food and in some industrial processes. Hydrogen chloride, when mixed with water (H 2 O), forms hydrochloric acid, a strong and commercially important acid. Other chlorine compounds include: chloroform (CHCl 3 ), carbon tetrachloride (CCl 4 ), potassium chloride (KCl), lithium chloride (LiCl), magnesium chloride (MgCl 2 ) and chlorine dioxide (ClO 2 ).

Chlorine is a very dangerous material. Liquid chlorine burns the skin and gaseous chlorine irritates the mucus membranes. Concentrations of the gas as low as 3.5 parts per million can be detected by smell while concentrations of 1000 parts per million can be fatal after a few deep breaths.

Estimated Crustal Abundance: 1.45×10 2 milligrams per kilogram

Estimated Oceanic Abundance: 1.94×10 4 milligrams per liter

Ionization Energy: 12.968 eV

Fosamax - Woman S Health, Teiroc

Fosamax is in the group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Fosamax slows bone loss while increasing bone mass, which may prevent bone fractures.

Take Fosamax exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Fosamax tablets are taken either once each day or once each week.

Take the Fosamax tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take a Fosamax tablet only once a week, take it on the same day each week and always first thing in the morning.

Take each Fosamax tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking a tablet. Do not crush, chew, or suck the Fosamax tablet. Swallow the pill whole.

After taking a Fosamax tablet, carefully follow these instructions: Do not lie down or recline for at least 30 minutes after taking Fosamax. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Fosamax. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure Fosamax is helping your condition, your bone mineral density will need to be tested on a regular basis. Visit your doctor regularly.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using this medicine. You may need to stop using the medicine for a short time.

Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

If you take Fosamax tablets once daily: If you forget to take this medicine first thing in the morning, do not take it later in the day. Wait until the following morning to take the medicine and skip the missed dose. Do not take two (2) tablets in one day.

If you take Fosamax tablets once a week: If you forget to take Fosamax on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly schedule on your chosen dose day. Do not take two (2) tablets in one day.

Treatment of Osteoporosis in Postmenopausal Women

The recommended dosage is: one 70 mg tablet once weekly one bottle of 70 mg oral solution once weekly one 10 mg tablet once daily

Prevention of Osteoporosis in Postmenopausal Women

The recommended dosage is: one 35 mg tablet once weekly one 5 mg tablet once daily

Treatment to Increase Bone Mass in Men with Osteoporosis

The recommended dosage is: one 70 mg tablet once weekly one bottle of 70 mg oral solution once weekly one 10 mg tablet once daily

Treatment of Glucocorticoid-Induced Osteoporosis

The recommended dosage is one 5 mg tablet once daily, except for postmenopausal women not receiving estrogen, for whom the recommended dosage is one 10 mg tablet once daily.

Treatment of Paget's Disease of Bone

The recommended treatment regimen is 40 mg once a day for six months.

Store at room temperature away from moisture and heat.

Do not take a Fosamax tablet if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.

You should not take Fosamax if you are allergic to alendronate, or if you have low levels of calcium in your blood (hypocalcemia), or a problem with the movement of muscles in your esophagus.

To make sure you can safely take Fosamax, tell your doctor if you have any of these other conditions:

trouble swallowing;

a vitamin D deficiency;

a dental problem;

kidney disease; or

an ulcer or other problem in your stomach or esophagus.

Some people using medicines similar to Fosamax have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.

You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.

Talk with your doctor about the risks and benefits of using Fosamax.

FDA pregnancy category C. It is not known whether Fosamax will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Do not use Fosamax without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction to Fosamax: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Fosamax and call your doctor at once if you have any of these serious side effects:

chest pain;

difficulty or pain when swallowing;

pain or burning under the ribs or in the back;

severe heartburn, burning pain in your upper stomach, or coughing up blood;

new or worsening heartburn;

fever, body aches, flu symptoms;

severe joint, bone, or muscle pain;

new or unusual pain in your thigh or hip;

jaw pain, numbness, or swelling.

Less serious Fosamax side effects may include:

mild heartburn, bloating;

mild nausea, vomiting, or stomach pain;

diarrhea, gas, or constipation;

mild joint pain or swelling;

swelling in your hands or feet; or

dizziness, eye pain, headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Retebem, Retebem

Other - Retebem (Brand name: oxytrol)

Oxytrol (oxybutynin) reduces muscle spasms of the bladder and urinary tract.

Oxytrol transdermal skin patch is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.

Oxytrol may also be used for purposes not listed in this medication guide.

Use Oxytrol exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Oxytrol comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

To use the Oxytrol patch, open the sealed pouch and remove the protective liner. Apply the transdermal patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is oily, irritated, or damaged. Avoid placing the patch on a skin area that will be rubbed by a waistband or tight clothing.

Press the Oxytrol patch onto the skin and press it down firmly with your fingers. Make sure the patch is well sealed around the edges. When properly applied, the patch should stay on while swimming or bathing.

Leave the Oxytrol patch in place and wear it for 3 to 4 days. You should change the patch twice per week. Each time you apply a new patch, choose a different skin area on your stomach, hip, or buttock. Do not apply a patch to the same skin twice within one week.

Try to change your Oxytrol patch on the same two days each week (such as every Sunday and Thursday). There is a calendar printed on the package of this medication to help you establish a steady patch-changing schedule.

If the patch falls off, try sticking it back on. If it does not stay on, replace it with a new one and wear it until your next regular patch-changing day. Do not change your schedule, even if you apply a new patch to replace one that has fallen off.

After removing an Oxytrol patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.

The Oxytrol patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test. Keep the Oxytrol patch in its sealed pouch until you are ready to use it.

Adults: The usual dose is 5mg two or three times a day. This may be increased to a maximum of 5 mg four times a day to obtain a clinical response provided that the side effects are tolerated. Elderly (including frail elderly): The elimination half-life is increased in the elderly. Therefore, a dose of 2.5mg twice a day, particularly if the patient is frail, is likely to be adequate. This dose may be titrated upwards to 5mg two times a day to obtain a clinical response provided the side effects are well tolerated. Children (under 5 years of age) : Not recommended. Children (over 5 years of age) : Neurogenic bladder instability: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are well tolerated. Nocturnal enuresis: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are tolerated. The last dose should be given before bedtime.

Store this medicine at room temperature in a tightly-closed container, away from heat and light.

Active ingredient: Oxybutynin

Do not use Oxytrol if you are allergic to oxybutynin, or if you have:

untreated or uncontrolled glaucoma;

a blockage in your digestive tract (stomach or intestines); or

if you have decreased urination or are unable to urinate.

To make sure you can safely use Oxytrol, tell your doctor if you have any of these other conditions:

an enlarged prostate;

an intestinal disorder, such as ulcerative colitis; or

a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. Oxytrol is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use Oxytrol without telling your doctor if you are breast-feeding a baby.

Important safety information:

Before using Oxytrol, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxybutynin.

Tell your doctor about all other medicines you use, especially:

atropine (Donnatal, and others);

hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E. E.S. EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek); or

antifungal medicine such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend).

This list is not complete and other drugs may interact with Oxytrol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Oxytrol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Oxytrol and call your doctor at once if you have a serious side effect such as:

fever with hot, dry skin;

uneven heart rate;

pain or burning when you urinate;

urinating less than usual or not at all; or

severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.

Less serious Oxytrol side effects may include:

mild skin itching, burning, redness, or discoloration where a patch was worn;

dizziness, drowsiness, weakness;

dry eyes, blurred vision;

warmth, tingling, or redness under your skin;

nausea, vomiting, stomach pain;

constipation or diarrhea;

feeling restless; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Ditropan is used for relieving symptoms of bladder problems (urinary urgency, frequency, or leakage; loss of bladder control; and painful urination) in certain patients. Ditropan is an anticholinergic. It works by relaxing muscles in the bladder.

Use Ditropan as directed by your doctor.

Take Ditropan by mouth with or without food.

Take Ditropan on a regular schedule to get the most benefit from it. Taking Ditropan at the same time each day will help you remember to take it.

Continue to take Ditropan event if you feel well. Do not miss any dose.

If you miss a dose of Ditropan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ditropan.

Store Ditropan at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tight container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ditropan out of the reach of children and away from pets.

Active Ingredient: Oxybutynin chloride.

Do NOT use Ditropan if:

you are allergic to any ingredient in Ditropan

you have bladder blockage or are unable to urinate

you have certain stomach or bowel problems (eg, blockage, decreased muscle movement) or tightening of the esophagus

you have uncontrolled narrow-angle glaucoma

you have heart problems caused by severe bleeding.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Ditropan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have trouble urinating or have very poor health

if you have a history of heart problems (eg, heart failure, fast or irregular heartbeat), high blood pressure, nervous system problems, esophagus problems (eg, reflux disease, inflammation), stomach or bowel problems (eg, colitis, inflammation), or hiatal hernia

if you have a history of liver or kidney problems, myasthenia gravis, an enlarged prostate, an overactive thyroid, or glaucoma, or if you are at risk for glaucoma.

Some medicines may interact with Ditropan. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergics (eg, scopolamine), azole antifungals (eg, ketoconazole), or macrolide antibiotics (eg, erythromycin) because they may increase the risk of Ditropan's side effects

Bisphosphonates (eg, alendronate) because the risk of irritation of the esophagus may be increased

Phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by Ditropan and they may increase the risk of Ditropan's side effects.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ditropan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Ditropan may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Ditropan with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ditropan; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

Ditropan may cause decreased sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur. Contact your doctor if you have been exposed to high temperatures and you develop fever; flushing; hot, dry skin; severe or persistent headache; dizziness; sudden fatigue; fast heartbeat; seizures; or fainting.

Ditropan may cause dry mouth. To help relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Ask your doctor or pharmacist if you have any questions.

Use Ditropan with caution in the elderly; they may be more sensitive to its effects.

Ditropan should be used with extreme caution in children younger 5 years; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: It is not known if Ditropan can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ditropan while you are pregnant. It is not known if Ditropan is found in breast milk. If you are or will be breast-feeding while you use Ditropan, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Blurred vision; constipation; diarrhea; dizziness; drowsiness; dry eyes, nose, skin, or mouth; headache; indigestion; nausea; stomach pain; taste changes; trouble sleeping.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficult or painful urination; fast or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, agitation); seizures; swelling of the hands, ankles, or feet; vision problems.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Sinacilin, Sinacilin

SINACILIN

ANTIBAKTERIJSKI LEKOVI ZA SISTEMSKU PRIMENU

J01CA penicilini sirokog spektra R 1021148 kapsula, tvrda; 500mg; blister, 2x8kaps. 3 godine, na temperaturi od 15-30°C, zasticeno od vlage i svetlosti Cuvati van domasaja dece R 1021145 kapsula, tvrda; 250mg; blister, 2x8kaps. 3 godine, na temperaturi od 15-30°C, zasticeno od svetlosti i vlage Cuvati van domasaja dece R 3021146 prasak za oralnu suspenziju; 250mg/5mL; bocica od tamnog stakla, 1x100m 3 godine, na temperaturi do 25°C u dobro zatvorenoj bocici R 2021147 prasak za oralnu suspenziju; 100mg/mL; bocica, 1x20mL 2 godine, na temperaturi do 25° C

Doziranje: terapija infekcija (izazvanih osetljivim mikroorganizmima) gornjih respiratornih puteva, usne duplje, zdrela, srednjeg uha, donjih respiratornih puteva, urogenitalnog trakta (ukljucujuci gonoreju), gastrointestinalnog trakta (ukljucujuci salmonelozne infekcije), lajmska bolest kod dece, infekcije koze i mekih tkiva i drugih infekcija izazvanih mikroorganizmima osetljivim na amoksicilin: odrasli i deca starija od 10 godina obicno 250-500mg na 8h, u zavisnosti od tezine infekcije, maks. 6g dnevno, u podeljenim dozama. Doza od 3g dva puta dnevno se preporucuje za lecenje teskih ili rekurentnih gnojnih respiratornih infekcija; eradikacija Helicobacter Pylori kod ulkusne bolesti uz terapiju inhibitorima protonske pumpe i drugim odgovarajucim antimikrobnim lekovima: po protokolu. Doze amoksicilna vece od uobicajenih, u obliku pojedinacnih doza, ili kratkotrajne terapije mogu se primeniti u sledecim indikacijama: nekomplikovane akutne urinarne infekcije odraslih: 2 puta po 3g u razmaku od 10-12h; dentalni apsces: 2 puta po 3g u razmaku od 8h; nekomplikovana gonoreja: jedna doza od 3g; profilaksa bakterijskog endokarditisa: odrasli 3g jedan sat pre stomatoloske intervencije sa ili bez lokalne anestezije. Ukoliko je neophodno, druga doza moze da se primeni 6h nakon prve doze. Prisustvo hrane ne utice znacajno na resorpciju leka. Deca uzrasta od 3 mes. do 10 god. uobicajena doza je 3 puta dnevno po 125mg; kod tezih infekcija doza se moze povecati na 3 puta dnevno po 250mg. Prema telesnoj masi uobicajene doze iznose 20-40mg/kg/dan, podeljeno u tri doze. Kod dece od 3-10 godina sa teskim ili rekurentnim otitis media moze se primeniti doza od 2 puta dnevno po 750mg, tokom 2 dana. Novorodencad i odojcad uzrasta do 3 mes. maks. doza iznosi 30mg/ kg/dan podeljeno u 2 doze. Kod dece (telesne mase do 40kg) sa bubreznom insuficijencijom doze treba korigovati. U odraslih osoba sa bubreznom insuficijencijom, kao i kod peritoneumske dijalize i hemodijalize potrebna je korekcija doza.

Paralelni lekovi . Amoksicilin, Amoxicillin, Ospamox®, Ospamox® DT

Reactine, Reactine

REACTINE ® Liquid Gels

REACTINE ® Extra Strength

REACTINE ® Regular Strength

REACTINE ® COMPLETE

REACTINE ® Liquid

REACTINE ® FAST MELT ™

REACTINE ® NaturEase

All natural REACTINE® NaturEase Nasal Spray offers that extra help for when your nasal symptoms are at their worst, helping reduce symptoms of dry, irritated nose and maintaining healthy sinuses.

Available in easily portable 10ml bottle. Note this product does not replace your allergy medicine. Use with REACTINE ® antihistamine for maximum relief.

Relieves :

HELPS CLEAR IRRITANTS FROM NASAL PASSAGE

SOOTHES AGAINST IRRITATION

SUPPORTS NATURAL DEFENSES

Dosage:

Adults: Apply 1 spray per treated nostril 4 times a day, if not otherwise prescribed by your healthcare provider. Simultaneously inhale gently through the treated nostril.

Children & Adolescents 5 – 18 years: Apply 1 spray per nostril 3 times a day (morning, lunchtime, evening), if not otherwise prescribed by your healthcare provider. Simultaneously inhale gently through the treated nostril.

Do not use for more than 6 weeks after opening. Consult a healthcare practitioner for use beyond 2 weeks.

Ingredients:

MEDICINAL INGREDIENTS: ectoine 2%, sodium chloride 0.9%

NON-MEDICINAL INGREDIENTS: water

Precautions:

Do not share this product with other users. Do not use after a nasal operation or injury of the nose. Do not use if you are allergic to ectoine. If an allergic reaction occurs, discontinue use immediately. If you are pregnant or breastfeeding, consult your healthcare provider or pharmacist for advice before using. If condition persists or worsens, contact your healthcare provider or pharmacist. Children should be supervised when using this product.

Do not use if security seal is missing or broken.

Store between 15 and 30 °C.

Cefaclor Side Effects In Detail, Cefcor

Cefaclor Side Effects

Diarrhea, genital pruritus or vaginitis, headache, nausea, vomiting, rash.

For Healthcare Professionals

Applies to cefaclor: oral capsule, oral powder for reconstitution, oral tablet chewable, oral tablet extended release

Gastrointestinal

If diarrhea occurs and it is unresponsive to discontinuation of the drug and/or standard therapy, pseudomembranous colitis should be considered. [Ref ]

Gastrointestinal side effects have included diarrhea, nausea, vomiting, and abdominal pain. Extended-release cefaclor has been associated with diarrhea (3.8%), nausea (3.4%), and anorexia, constipation, dyspepsia, flatulence, gastritis, nausea and vomiting, and vomiting in 0.1% to 1% of patients. Pseudomembranous colitis has been reported in patients treated with cephalosporins. [Ref ]

Hypersensitivity

Anaphylactic reactions are rare, but may occur, especially in patients with a history of penicillin allergy.

Serum-sickness-like reactions are more frequent in pediatric patients and following a second or subsequent course of cefaclor and have been characterized by erythema multiforme, rash, arthritis, and/or arthralgia with or without fever. [Ref ]

Hypersensitivity reactions have included rash, morbilliform eruptions (1%), pruritus, serum-sickness-like reactions, urticaria, anaphylactic reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylactoid reaction, and angioedema. [Ref ]

Hepatic

Hepatic side effects have included slight elevations AST, ALT, and alkaline phosphatase in 2.5% of patients. Extended-release cefaclor has been associated with increased ALT (0.3%), increased alkaline phosphatase (0.3%), increased bilirubin (0.3%), increased creatine phosphokinase (0.7%), and increased GGT (0.2%). Cephalosporins as a class have been associated with elevated LDH, hepatic dysfunction, and cholestasis. [Ref ]

Renal

One case report of acute interstitial nephritis and nonoliguric renal failure has been reported following cefaclor therapy. (Reversible fever, azotemia, pyuria, and eosinophiluria are the hallmarks of cephalosporin-induced interstitial nephritis.) [Ref ]

Renal side effects have included transient elevations in blood urea nitrogen (BUN) and serum creatinine in 0.2% of patients, reversible interstitial nephritis (rare), and abnormal urinalysis (0.5%). Extended-release cefaclor has been associated with increased BUN (0.2%), and increased creatinine (0.5%). Cephalosporins as a class have been associated with toxic nephropathy, reversible interstitial nephritis, and renal dysfunction. [Ref ]

Hematologic

Hematologic side effects have included eosinophilia (2%), positive Coombs' test (less than 0.5%), leukopenia, thrombocytosis, transient thrombocytopenia (rare), transient lymphocytosis, hemolytic anemia, aplastic anemia, agranulocytosis, and reversible neutropenia. Extended-release cefaclor has been associated with increased eosinophils (0.3%), decreased erythrocyte count (0.3%), decreased hemoglobin (0.2%), decreased lymphocytes (0.3%), increased mean cell volume (0.7%), decreased segmented neutrophils (0.3%), and decreased platelet count (0.4%). Cephalosporins as a class have been associated with hemorrhage and pancytopenia. [Ref ]

Genitourinary

Genitourinary side effects have included genital pruritus and vaginitis in less than 1% of patients. Extended-release cefaclor has been associated with vaginitis (2.4%) and vaginal moniliasis (2.2%), and dysmenorrhea, dysuria, leukorrhea, menstrual disorder, and nocturia in 0.1% to 1% of patients. Cephalosporins as a class have been associated with false-positive tests for urine glucose. [Ref ]

Nervous system

Nervous system side effects have rarely included reversible hyperactivity, agitation, nervousness, insomnia, confusion, hypertonia, dizziness, hallucinations, and somnolence. Extended release cefaclor has been associated with headache in 4.9% of patients, and dizziness, insomnia, nervousness, somnolence, and tremor in 0.1% to 1% of patients, and paresthesia and vertigo. Some cephalosporins have been associated with seizures, primarily when dosages were not reduced in renally impaired patients. [Ref ]

Other

Other side effects associated with extended-release cefaclor have included abdominal pain (1.6%), back pain (1%), and accidental injury, chest pain, chills, ear pain, fever, flu syndrome, infection, malaise, neck pain, otitis media, pain, and surgical procedure in 0.1% to 1% of patients. Cephalosporins as a class have been associated with abdominal pain, fever, and superinfection. [Ref ]

Respiratory

Respiratory side effects associated with extended-release cefaclor have included rhinitis (3.9%), increased cough (1.5%), pharyngitis (1.4%), and asthma, bronchitis, lung disorder, respiratory disorder, and sinusitis in 0.1% to 1% of patients. [Ref ]

Dermatologic

Dermatologic side effects have included pruritus, maculopapular rash, rash, and urticaria. [Ref ]

Musculoskeletal

Musculoskeletal side effects associated with extended-release cefaclor have included arthralgia and myalgia in 0.1% to 1% of patients. [Ref ]

Cardiovascular

Cardiovascular side effects associated with extended-release cefaclor have included congestive heart failure (0.1% to 1%), edema (0.1% to 1%), palpitation (0.1% to 1%), peripheral edema (0.1% to 1%), hypotension, face edema, vasodilatation, and syncope. [Ref ]

Ocular

Ocular side effects associated with extended-release cefaclor have included conjunctivitis (0.1% to 1%). [Ref ]

Endocrine

Endocrine side effects associated with extended-release cefaclor have included sweating (0.1% to 1%). [Ref ]

Metabolic

Metabolic side effects associated with extended-release cefaclor have included decreased albumin (0.3%), decreased calcium (0.7%), increased creatine phosphokinase (0.7%), increased phosphorus (0.7%), increased potassium (0.4%), decreased sodium (0.3%), and increased sodium (0.4%). [Ref ]

References

1. Quenzer RW, Davis RL, Neidhart MM "Prospective randomized study comparing the efficacy and safety of ciprofloxacin with cefaclor in the treatment of patients with purulent bronchitis." Diagn Microbiol Infect Dis 13 (1990): 143-8

2. "Product Information. Ceclor CD (cefaclor)." Dura Pharmaceuticals, San Diego, CA.

3. Hyslop DL "Cefaclor safety profile: a ten-year review." Clin Ther 11 Suppl A (1988): 83-94

4. Goumas P, Naxakis S, Bassaris C, Skoutelis A "Comparative efficacy and tolerability of clarithromycin and cefaclor in the treatment of outpatients with acute maxillary sinusitis." Clin Drug Invest 13 (1997): 128-33

5. "Product Information. Ceclor (cefaclor)." Lilly, Eli and Company, Indianapolis, IN.

6. Reynolds RD "Cefaclor and serum sickness-like reaction." JAMA 276 (1996): 950

7. Boyd LW "Cefaclor-associated serum sickness." Med J Aust 169 (1998): 443-4

8. Beghetti M, Wilson GJ, Bohn D, Benson L "Hypersensitivity myocarditis caused by an allergic reaction to cefaclor." J Pediatr 132 (1998): 172-3

9. Ackley AM, Felsher J "Adverse reactions to cefaclor." South Med J 74 (1981): 1550

10. Filipe P, Almeida RSLS, Rodrigo FG "Occupational allergic contact dermatitis from cephalosporins." Contact Dermatitis 34 (1996): 226

11. Hama R, Mori K "High incidence of anaphylactic reactions to cefaclor." Lancet 06/11/88 (1988): 1331

12. Grouhi M, Hummel D, Roifman CM "Anaphylactic reaction to oral cefaclor in a child." Pediatrics 103 (1999): e50

13. Christensen JC, Swenson E, Gooch WM, Herrod JN "Comparative efficacy and safety of cefprozil (BMY-28100) and cefaclor in the treatment of acute group A beta-hemolytic streptococcal pharyngitis." Antimicrob Agents Chemother 35 (1991): 1127-30

14. Pommer W, Krause PH, Berg PA, et al "Acute interstitial nephritis and non-oliguric renal failure after cefaclor treatment." Klin Wochenschr 64 (1986): 290-3

15. "Multum Information Services, Inc. Expert Review Panel"

Not all side effects for cefaclor may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .

More about cefaclor

Consumer resources

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill. knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Drug Status

Tensobon Indication, Action Of Tensobon, Interactions, Tensobon

Tensobon [in more detail]

For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.

Tensobon Mechanism Of Action:

Tensobon competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative feedback mediator for renin activity, lower angiotensin II levels results in a decrease in blood pressure, an increase in renin activity, and stimulation of baroreceptor reflex mechanisms. Kininase II, an enzyme which degrades the vasodilator bradykinin, is identical to ACE and may also be inhibited.

Tensobon Drug Interactions:

Amiloride Increased risk of hyperkaliemia Drospirenone Increased risk of hyperkaliemia Lithium The ACE inhibitor increases serum levels of lithium Potassium Increased risk of hyperkaliemia Spironolactone Increased risk of hyperkaliemia Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor Triamterene Increased risk of hyperkaliemia

Food Interactions:

Avoid alcohol. Avoid salt substitutes containing potassium. Take on empty stomach: 1 hour before or 2 hours after meals, food decreases absorption by 30 to 55%. Avoid natural licorice. Do not take calcium, aluminum, magnesium or Iron supplements within 2 hours of taking this medication.

Tensobon Chemical Formula:

Buy Generic For Tabphyn, Tabphyn

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Generic Name: Tamsulosin

Generic for Tabphyn* (Tamsulosin) is used to treat the symptoms of benign prostatic hyperplasia (BPH), which is also known as enlarged prostate. By relaxing the muscles in the bladder neck and prostate, Tamsulosin helps relieve BPH symptoms such as urinary frequency, urinary urgency, and so on. This medicine belongs to a group of drugs called alpha-adrenergic blockers. This medicine may also be used to treat other conditions as determined by your doctor. Read More>>

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What is Generic for Tabphyn* used for?

Generic for Tabphyn* (Tamsulosin) is used to treat the symptoms of benign prostatic hyperplasia (BPH), which is also known as enlarged prostate. By relaxing the muscles in the bladder neck and prostate, Tamsulosin helps relieve BPH symptoms such as urinary frequency, urinary urgency, and so on. This medicine belongs to a group of drugs called alpha-adrenergic blockers. This medicine may also be used to treat other conditions as determined by your doctor.

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What are the questions to ask your doctor before taking Generic for Tabphyn*?

Is it possible for me to take Generic for Tabphyn* with other drugs? Should certain beverages, foods and other products be avoided when I take Generic for Tabphyn*? What are the possible drug interactions of Generic for Tabphyn*? How will Generic for Tabphyn* work in my body? How should Generic for Tabphyn* be taken? How to reduce the risk of Generic for Tabphyn* drug interactions and side effects?

Note

The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Generic for Tabphyn* is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

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Coverex-as Marketing Information

Coverex-as Description

Coverex-as is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys.

This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure.

Generic name of Coverex-as is Perindopril.

Brand name of Coverex-as is Coverex-as.

Coverex-as Dosage

Coverex-as is available in:

2mg Low Dosage4mg Standard Dosage

The usual starting dosage is 4 milligrams daily, taken as a single dose or divided into two smaller doses.

If you want to achieve most effective results do not stop taking Coverex-as suddenly.

Coverex-as Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Coverex-as Overdose

If you overdose Coverex-as and you don't feel good you should visit your doctor or health care provider immediately.

Coverex-as Side effects

Coverex-as has its side effects. The most common are:

coughdizzinessheadacheleg painlight-headednessnasal inflammationsore throatupper respiratory infectionweakness

Less common but more serious side effects during taking Coverex-as: allergy reactions (urticaria, breathing difficulties, rash, and eruption)

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Coverex-as Contra-indications

Do not take Coverex-as if you are allergic to Coverex-as components.

Be careful with Coverex-as if you're pregnant or you plan to have a baby, or you are a nursing mother.

Do not use potassium supplements or salt substitutes.

If you want to achieve most effective results without any side effects it is better to avoid alcohol.

Be very careful when you are driving machine.

Coverex-as may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch you eyes or the inside of your nose unless you have thoroughly washed your hands first.

Do not stop taking Coverex-as suddenly.

Coverex-as Frequently asked questions

Q: What is Coverex-as?

A: Coverex-as is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease. Coverex-as is an angiotensin-converting enzyme (ACE) inhibitor.

Q: In what way does Coverex-as work?

A: It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys.

Q: Does the generic available?

A: Yes, generic is available. Generic name of Coverex-as is Perindopril.

Q: Can I mix alcohol with Coverex-as tablets?

A: No. Do not use alcohol while taking Coverex-as.

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Fiambutol (Myambutol) Explicacion

Fiambutol es en realidad hasta al dia a traves de profesionales de la salud con el fin de luchar contra la tisis. Concentrese en asociado con Fiambutol seria para prevenir, extremo, asi como eliminar los germenes que se distribuyen a traves de tisis.

Fiambutol puede pasar como tratamiento contra la tuberculosis. Fiambutol funciona a traves de la eliminacion de los germenes tisis.

Fiambutol es en realidad hormigueros bacterias agente de bienes raices.

Fiambutol puede ser usado en conjunto con otros medicamentos contra la tuberculosis.

Fiambutol no permite proporcionar a los enfermos de debajo de trece anos.

titulo general asociada con Fiambutol es en realidad etambutol.

Marca asociada con Fiambutol Fiambutol es en realidad.

Fiambutol (Myambutol) Dosis

Fiambutol viene en:

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Es recomendable considerar Fiambutol cada dia al mismo tiempo junto con lacteos, alimentos o incluso sin tener esto.

Usted puede hacer Fiambutol con respecto a 1-2 anos.

Por lo general, no utilizan los antiacidos, los que incluyen hidroxido de aluminio ligero de peso, no menos de cuatro horas inmediatamente despues de la utilizacion Fiambutol.

Fiambutol puede ser usado en conjunto con otros medicamentos contra la tuberculosis.

Fiambutol no permite proporcionar a los enfermos de debajo de trece anos.

Por lo general, no dejar de fumar usando Fiambutol de repente.

Fiambutol (Myambutol) Careciendo asocia con dosis

Por lo general, no reciben doble dosis. En caso de que salte la dosis que necesita para llevar una vez se tiene en cuenta en lo que respecta a su deficiente. Cuando es hora de la dosis que necesita para llevar a cabo su propia rutina de dosificacion normal.

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En el caso de una sobredosis Fiambutol y que tambien se evita gran usted necesita comprobar hacia fuera su medico o incluso el medico de inmediato.

Fiambutol (Myambutol) Espacio de almacenamiento

La tienda de las temperaturas del espacio entre los veinte, asi como veinticinco niveles D (68, asi como setenta y siete niveles F) de humedad, asi como la temperatura. Fortalecer cualquier tipo de medicamento sin tocar a partir del dia de vencimiento. Mantener desde el lograr de los ninos.

Fiambutol (Myambutol) Efectos negativos

Fiambutol ofrece los efectos negativos. El mas tipico tienden a ser:

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Mucho menos efectos negativos tipicos y graves en todo usando Fiambutol:

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Los efectos negativos indicaciones se basan en la medicacion usted podria estar usando pero, ademas, confia en su condicion de bienestar y otros aspectos

Fiambutol (Myambutol) Contraindicaciones

Por lo general, no utilizan Fiambutol en caso de que usted es sensible con el fin de Fiambutol elementos.

Por lo general, no utilizan Fiambutol si usted esta esperando otra manera tiene la intencion de tener un hijo, si no que realmente eres una mama medica.

Por lo general, no utilizan Fiambutol en caso de conseguir la hinchazon de la neural optica.

Juega el papel de cautela, junto con la utilizacion de Fiambutol en caso de conseguir organo higado o enfermedad renal, incluso, el dolor de gota asalto, dolor de la gota, los ojos repetidas hinchazon junto con otras cuestiones de ojos, cataratas, enfermedad de las articulaciones gotosa.

Juega el papel de cautela, junto con la utilizacion de Fiambutol en el caso de la utilizacion de este tipo de medicina porque sales de aluminio de peso ligero, antiacidos.

Fiambutol no permite proporcionar a los enfermos de debajo de trece anos.

Si usted desea lograr mejores resultados, sin efectos negativos, es aconsejable evitar las bebidas alcoholicas.

Tenga cuidado junto con dosis Fiambutol simplemente porque la terapia que sale por un largo periodo puede causar una contaminacion adicional. Usted podria hacer Fiambutol con respecto a 1-2 anos.

Mantengase alejado de dispositivo de viajar.

Evite las bebidas alcoholicas.

Puede ser danino para evitar el uso de Fiambutol de repente.

Fiambutol (Myambutol) Preguntas comunes

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Queen: ?Que son exactamente los de marca, asi como las marcas generales asociados con Fiambutol?

El: titulo general asociada con Fiambutol es en realidad etambutol. Marca asociada con Fiambutol es en realidad Fiambutol. A

Queen: ?Que es exactamente esencial para prevenir?

El: Por lo general no utilizan Fiambutol en caso de conseguir la hinchazon de la neural optica. Si usted desea lograr mejores resultados, sin efectos negativos, es aconsejable evitar las bebidas alcoholicas. Sea cauteloso junto con dosis Fiambutol simplemente porque la terapia que procede durante un largo periodo puede causar una contaminacion adicional. Usted podria hacer Fiambutol con respecto a 1-2 anos. Mantengase alejado de viajar dispositivo. Puede ser danino para evitar Fiambutol utilizando todos un sudden. A

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El: Fiambutol es en realidad hasta al dia a traves de profesionales de la salud con el fin de luchar contra la tisis. Enfoque en asociado con Fiambutol seria para evitar que, al final, asi como eliminar los germenes que se distribuyen a traves de tisis. A

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Liaise - Definition Of Liaise In English, Luase

Definition of liaise in English:

‘she will liaise with teachers across the country’

More example sentences

‘Surely, you can liaise with counsel in that matter, do you think?’

‘He and his men will control the camp's perimeter and mount patrols to secure the area and liaise with nearby communities.’

‘You need to be well organised and flexible to ensure that you meet your deadlines and have good communication skills, as you will be liaising with both guests and suppliers.’

‘He confirmed his officers were liaising with other forces, and said that although there was no scientific evidence to link the three cases, there were similarities.’

‘Police are also keeping an open mind as to a possible racial motive and are liaising with community leaders in the area.’

‘We attend their meetings, we liaise with them, find out local concerns and work together with them in the interests of local people.’

‘Businesses in the City of London have been extensively briefed, and police have liaised with leaders of community groups which could be targeted.’

‘The government is also to consider the appointment of consultants to liaise with local communities on the hosting of asylum seekers.’

‘She has liaised with the community, built the school's special needs department and mentors every new teacher.’

‘We have liaised with the community to open up sections of bridleways.’

‘This is where support workers, such as Caroline, step in to improve links with schools and liaise with teachers.’

‘Soldiers liaise and mix with community members while maintaining their professional bearing.’

‘‘Now that it has been brought to our attention again, we will be liaising with the police to see if we can find a quick solution,’ he added.’

‘The battalion's Civil Military Affairs representatives liaised with local communities to explain what they would see and hear during the fire mission.’

‘At the same time detectives will be liaising with York police for any intelligence they can offer.’

‘I worked closely with a changing House Committee and liaised closely with staff from the Hawthorn Council.’

‘Organisers are liaising with the locals to make sure pilots don't land on crops, and the roar of the balloon's burners doesn't spook sheep and cattle.’

‘Matt visited other cities to investigate how they dealt with kerb crawlers and liaised with their community action teams on the best approach to deal with the problem.’

‘Company sources say it liaised with government officials for some time on putting together such an event, but it now fears it may be edged out.’

‘We will be liaising with young people, parents, schools and our partner agencies across the borough to try to reduce problems concerning local youngsters.’

cooperate . work together, collaborate

communicate . intercommunicate, exchange information, network, interface, link up, hook up

1.1 Act as a link to assist communication between (people or groups)

‘civil servants who liaise between the prime minister and departmental ministers’

More example sentences

‘Its objective is to liaise between prospective job seekers and employers in this region.’

‘They are the ones responsible for the use of public funds, and the crucial role of liaising between both the people working on the project and the people who are funding or backing the project.’

‘Most agencies have a group of people called account executives who are responsible for liaising between the client and the agency staff who work on the account.’

‘He will also be helping to liaise between local communities and conservation projects to find ways to protect the animals.’

‘They visit scenes of death and attend autopsies, take witness statements and liaise between traumatised relatives, police, solicitors and doctors.’

‘The key ability was to be able to liaise between the creditors and the banks.’

‘The role would involve liaising between the community and relevant interested groups.’

‘He says the committee's role is to liaise between the Department of Agriculture and other agencies, and ‘the common ordinary person’.’

‘First of all, they are supposed to liaise between the two families.’

‘‘Basically the committee is a body set up to liaise between general practitioners and hospitals and hearing concerns,’ he said.’

‘There is a greater need for liaising between club and school than ever before.’

Origin

1920s (originally military slang): back-formation from liaison.

Pronunciation:

Azyter - Summary Of Product Characteristics (Spc), Azyter

* Clinical effectiveness is demonstrated by sensitive isolated organisms for approved indications.

$ Natural intermediate susceptibility.

1 Conjunctivitis caused by Neisseria gonorrhoeae require a systemic treatment (see section 4.4).

Information from clinical trials

- Trachomatous conjunctivitis caused by Chlamydia trachomatis .

Azyter was evaluated in a two-month, randomised, double-masked study comparing Azyter with a single oral dose of azithromycin for the treatment of trachoma in 670 children (1-10 years). The primary efficacy variable was the clinical cure at Day 60, i. e. a grade TF0 (simplified WHO grading scale). At Day 60, clinical cure rate of Azyter instilled twice daily for 3 days (96.3%) was non-inferior to that of oral azithromycin (96.6%).

The clinical efficacy of Azyter (instilled twice daily for 3 days) in mass curative and prophylactic treatment of trachoma in an entire population (from birth) in a northern Cameroon district (112 000 subjects) was assessed in a multicentre, open-label, single-arm, phase IV study. Three annual reatment periods were performed. The primary efficacy endpoint was the prevalence of active trachoma, i. e. trachomatous inflammation-follicular or trachomatous inflammation-intense (TF+TI0 or TF+TI+). For analysis, clinical assessment of trachoma was performed each year in a sample of 2400 children aged ≥1 and < 10 years old selected using a random cluster sampling. The prevalence of active trachoma (TF+TI0 or TF+TI+) was 31.1% at Year 0 (before Azyter instillations) and decreased to 6.3% at Year 1, 3.1% at Year 2 and 3.1% at Year 3.

In the whole population, there was no serious adverse event in relation with the study drug.

- Purulent bacterial conjunctivitis.

Azyter was evaluated in a randomised, investigator-masked study comparing Azyter, instilled twice daily for 3 days, with tobramycin 0.3% eye drops, instilled every two hours for 2 days then four times daily for 5 days, for the treatment of purulent bacterial conjunctivitis in 1043 patients (ITT set), including 109 children up to the age of 11 years from whom 5 were newborn infants (0 to 27 days) and 38 infants and toddlers (28 days to 23 months of age). In the Per Protocol set (n=471), there were no newborns and only 16 infants and toddlers. The clinical study was performed in different areas in Europe, North Africa, and India. The primary efficacy variable was the clinical cure at Day 9 in the PP set, defined as a score of 0 for both the bulbar conjunctival injection and the purulent discharge. At Day 9, clinical cure rate of Azyter (87.8%) was non-inferior to that of tobramycin (89.4%).

Microbiological resolution rate of Azyter was comparable to that of tobramycin.

The efficacy and safety of Azyter in paediatric patients ≤ 18 years of age was demonstrated in a randomised, investigator-masked study compared with tobramycin in 282 analysed patients diagnosed with purulent bacterial conjunctivitis (including 148 patients in the subgroup 0 day - < 24 months).

Patients received either Azyter, instilled twice daily for 3 days or tobramycin 0.3% eye drops, instilled every two hours for 2 days then four times daily for 5 days. The primary efficacy endpoint was the clinical cure in the worse eye on D3 for patients with D0 positive bacterial cultures. Clinical cure in the worse eye on D3 was demonstrated to be significantly superior for Azyter (47%) than for tobramycin (28%). At D7, 89% of patients treated with Azyter were cured versus 78% with tobramycin. No statistical difference was found between treatment groups for the bacteriological resolution at D7.

Azyter (instilled twice daily for 3 days) was well-tolerated in all age groups in this large study in paediatric population. The events observed in paediatric subjects were a subset of those previously observed in adults; no new adverse events were identified in paediatric subjects. Furthermore, no age-related patterns of clinical concern were evident. The short duration of Azithromycin 1.5% treatment, the low number of instillations needed and the easiness of instilling drops in children were appreciated by both children and parents.

5.2 Pharmacokinetic properties

Azithromycin was not detected in the blood of patients with bacterial conjunctivitis after instillation of Azyter at the recommended dose (detection limit: 0.0002 μg/mL of plasma).

Pharmacokinetic studies have only been performed in adults.

5.3 Preclinical safety data

In animals, azithromycin caused reversible phospholipidosis. This effect was seen after oral exposures which were about 300 times in excess of the maximum human exposure after ocular administration indicating little relevance to clinical use.

Electrophysiological investigations have shown that azithromycin prolongs the QT interval.

Long-term studies in animals have not been performed to evaluate carcinogenic potential.

There was no evidence of a potential for genetic and chromosome mutations in in vivo and in vitro test models.

No teratogenic effects were observed in embryotoxicity studies in rats after oral administration of azithromycin. In rats, azithromycin dosages of 100 and 200 mg/kg body weight/day led to mild retardations in fetal ossification and in maternal weight gain. In peri - and postnatal studies in rats, mild retardations following treatment with 50 mg/kg/day azithromycin and above were observed. These effects were seen after oral administration at exposures which were about 1000 times in excess of the maximum human exposures after ocular administration. Because of the high safety margin, these findings do not point to a relevant risk for human reproduction.

Ocular administration of Azyter eye drops to animals twice or three times a day during 28 days did not demonstrate any local or systemic toxic effect.

6. Pharmaceutical particulars

6.1 List of excipients

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Common Side Effects Of Benicar (Olmesartan Medoxomil) Drug Center, Benacort

For Patients

Last reviewed on RxList 5/22/2015

Benicar (olmesartan medoxomil) is an angiotensin II receptor antagonist used to reduce and control hypertension (high blood pressure). Generic Benicar is available outside of the U. S. Common side effects of Benicar include dizziness, bronchitis, back pain, joint or muscle pain, stomach pain, nausea, diarrhea, itching or skin rash, weakness, headache, flu-like symptoms, blood in the urine, and sinus infections.

Benicar is available in strengths of 5, 20, or 40 mg of olmesartan medoxomil tablets. The usual recommended starting dose is 20 mg per day but dosage in pediatric patients needs to be calculated for each individual. Potentially serious side effects include difficulty with breathing or swallowing, chest pain, cough, vertigo, abdominal pain, hyperkalemia, renal failure, and rhabdomyolysis. Benicar should not be used in pregnancy due to possible fetal damage or death; lactating women and their doctors need to weigh the advantages vs the possible harm if the drug is used. There is only one study in pediatric patients (ages 1-16 years) that suggests that Benicar is well tolerated with similar side effects seen in adults.

Our Benicar Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Benicar in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

feeling like you might pass out;

urinating less than usual or not at all;

chest pain, fast heart rate; or

swelling in your hands or feet.

Less serious side effects may include:

dizziness;

joint or muscle pain;

back pain;

stomach pain, nausea, diarrhea;

mild itching or skin rash; or

weakness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Benicar (Olmesartan Medoxomil)

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Benicar Overview - Patient Information: Side Effects

SIDE EFFECTS: Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: fainting, symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat), unusual decrease in the amount of urine, severe/persistent diarrhea.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Benicar (Olmesartan Medoxomil)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Benicar FDA Prescribing Information: Side Effects (Adverse Reactions)

SIDE EFFECTS

Clinical Trials Experience

Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Adult Hypertension

Benicar has been evaluated for safety in more than 3825 patients/subjects, including more than 3275 patients treated for hypertension in controlled trials. This experience included about 900 patients treated for at least 6 months and more than 525 for at least 1 year. Treatment with Benicar was well tolerated, with an incidence of adverse reactions similar to placebo. Events generally were mild, transient and had no relationship to the dose of Benicar .

The overall frequency of adverse reactions was not dose-related. Analysis of gender, age and race groups demonstrated no differences between Benicar and placebo-treated patients. The rate of withdrawals due to adverse reactions in all trials of hypertensive patients was 2.4% (i. e. 79/3278) of patients treated with Benicar and 2.7% (i. e. 32/1179) of control patients. In placebo-controlled trials, the only adverse reaction that occurred in more than 1% of patients treated with Benicar and at a higher incidence versus placebo was dizziness (3% vs. 1%).

The following adverse reactions occurred in placebo-controlled clinical trials at an incidence of more than 1% of patients treated with Benicar. but also occurred at about the same or greater incidence in patients receiving placebo: back pain. bronchitis. creatine phosphokinase increased, diarrhea, headache, hematuria. hyperglycemia. hypertriglyceridemia, influenza - like symptoms, pharyngitis. rhinitis and sinusitis .

The incidence of cough was similar in placebo (0.7%) and Benicar (0.9%) patients.

Other potentially important adverse reactions that have been reported with an incidence of greater than 0.5%, whether or not attributed to treatment, in the more than 3100 hypertensive patients treated with Benicar monotherapy in controlled or open-label trials are listed below.

Body as a Whole: chest pain, peripheral edema

Central and Peripheral Nervous System: vertigo

Heart Rate and Rhythm Disorders: tachycardia

Skin and Appendages: rash

Facial edema was reported in five patients receiving Benicar. Angioedema has been reported with angiotensin II antagonists.

Laboratory Test Findings

In controlled clinical trials, clinically important changes in standard laboratory parameters were rarely associated with administration of Benicar .

Hemoglobin and Hematocrit : Small decreases in hemoglobin and hematocrit (mean decreases of approximately 0.3 g/dL and 0.3 volume percent, respectively) were observed.

Liver Function Tests : Elevations of liver enzymes and/or serum bilirubin were observed infrequently. Five patients (0.1%) assigned to Benicar and one patient (0.2%) assigned to placebo in clinical trials were withdrawn because of abnormal liver chemistries (transaminases or total bilirubin). Of the five Benicar patients, three had elevated transaminases, which were attributed to alcohol use, and one had a single elevated bilirubin value, which normalized while treatment continued.

Pediatric Hypertension

No relevant differences were identified between the adverse experience profile for pediatric patients aged 1 to16 years and that previously reported for adult patients.

Post-Marketing Experience

The following adverse reactions have been reported in post-marketing experience. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Metabolic and Nutritional Disorders . Hyperkalemia

Urogenital System: Acute renal failure. increased blood creatinine levels

Data from one controlled trial and an epidemiologic study have suggested that high-dose olmesartan may increase cardiovascular (CV) risk in diabetic patients, but the overall data are not conclusive. The randomized, placebo-controlled, double-blind ROADMAP trial (Randomized Olmesartan And Diabetes MicroAlbuminuria Prevention trial, n=4447) examined the use of olmesartan, 40 mg daily, vs. placebo in patients with type 2 diabetes mellitus. normoalbuminuria, and at least one additional risk factor for CV disease. The trial met its primary endpoint, delayed onset of microalbuminuria. but olmesartan had no beneficial effect on decline in glomerular filtration rate (GFR). There was a finding of increased CV mortality (adjudicated sudden cardiac death, fatal myocardial infarction. fatal stroke. revascularization death) in the olmesartan group compared to the placebo group (15 olmesartan vs. 3 placebo, HR 4.9, 95% confidence interval [CI], 1.4, 17), but the risk of non-fatal myocardial infarction was lower with olmesartan (HR 0.64, 95% CI 0.35, 1.18).

The epidemiologic study included patients 65 years and older with overall exposure of > 300,000 patient-years. In the sub - group of diabetic patients receiving high-dose olmesartan (40 mg/d) for > 6 months, there appeared to be an increased risk of death (HR 2.0, 95% CI 1.1, 3.8) compared to similar patients taking other angiotensin receptor blockers. In contrast. high-dose olmesartan use in non-diabetic patients appeared to be associated with a decreased risk of death (HR 0.46, 95% CI 0.24, 0.86) compared to similar patients taking other angiotensin receptor blockers. No differences were observed between the groups receiving lower doses of olmesartan compared to other angiotensin blockers or those receiving therapy for < 6 months.

Overall, these data raise a concern of a possible increased CV risk associated with the use of highdose olmesartan in diabetic patients. There are, however, concerns with the credibility of the finding of increased CV risk, notably the observation in the large epidemiologic study for a survival benefit in non-diabetics of a magnitude similar to the adverse finding in diabetics.

Read the entire FDA prescribing information for Benicar (Olmesartan Medoxomil)

Buy Moxatid - Amoxicillin, Clavulanate - Online Without Prescriptions, Moxatid

Augmentin (Moxatid)

Augmentin is used for treating infections caused by certain bacteria. Augmentin is a penicillin antibiotic. It works by killing sensitive bacteria.

Use Augmentin as directed by your doctor.

Take Augmentin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, take Augmentin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Augmentin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Augmentin.

Store Augmentin at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Augmentin out of the reach of children and away from pets.

Active Ingredient: Amoxicillin/clavulanate potassium.

Do NOT use Augmentin if:

you are allergic to any ingredient in Augmentin or another penicillin antibiotic (eg, ampicillin)

you have a history of liver problems or yellowing of the eyes or skin caused by Augmentin

you have infectious mononucleosis (mono)

you are taking a tetracycline antibiotic (eg, doxycycline)

you have recently received or will be receiving live oral typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Augmentin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of allergies, asthma, hay fever, or hives

if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)

if you have kidney problems or gonorrhea

if you have a history of liver problems or yellowing of the eyes or skin.

Some medicines may interact with Augmentin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Probenecid because it may increase the amount of Augmentin in your blood

Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Augmentin's effectiveness

Methotrexate because the risk of its side effects may be increased by Augmentin

Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Augmentin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Augmentin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Augmentin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Augmentin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Augmentin only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Augmentin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Augmentin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Augmentin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Augmentin. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.

Diabetes patients - Augmentin may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Augmentin for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Augmentin with caution in the elderly; they may be more sensitive to its effects, especially patients with kidney problems.

Use Augmentin with extreme caution in children younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

Augmentin should not be used in children who weigh less than 88 lbs (40 kg); safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Augmentin while you are pregnant. Augmentin is found in breast milk. If you are or will be breast-feeding while you use Augmentin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Augmentin (Moxatid)

Augmentin is used for treating infections caused by certain bacteria. Augmentin is a penicillin antibiotic. It works by killing sensitive bacteria.

Use Augmentin as directed by your doctor.

Take Augmentin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, take Augmentin for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Augmentin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Augmentin.

Store Augmentin at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Augmentin out of the reach of children and away from pets.

Active Ingredient: Amoxicillin/clavulanate potassium.

Do NOT use Augmentin if:

you are allergic to any ingredient in Augmentin or another penicillin antibiotic (eg, ampicillin)

you have a history of liver problems or yellowing of the eyes or skin caused by Augmentin

you have infectious mononucleosis (mono)

you are taking a tetracycline antibiotic (eg, doxycycline)

you have recently received or will be receiving live oral typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Augmentin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of allergies, asthma, hay fever, or hives

if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)

if you have kidney problems or gonorrhea

if you have a history of liver problems or yellowing of the eyes or skin.

Some medicines may interact with Augmentin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Probenecid because it may increase the amount of Augmentin in your blood

Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Augmentin's effectiveness

Methotrexate because the risk of its side effects may be increased by Augmentin

Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Augmentin.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Augmentin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Augmentin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Augmentin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Augmentin only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Augmentin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Augmentin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Hormonal birth control (eg, birth control pills) may not work as well while you are using Augmentin. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Augmentin. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.

Diabetes patients - Augmentin may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Augmentin for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Augmentin with caution in the elderly; they may be more sensitive to its effects, especially patients with kidney problems.

Use Augmentin with extreme caution in children younger than 10 years old who have diarrhea or an infection of the stomach or bowel.

Augmentin should not be used in children who weigh less than 88 lbs (40 kg); safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Augmentin while you are pregnant. Augmentin is found in breast milk. If you are or will be breast-feeding while you use Augmentin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Daparox E Sonnolenza, Daparox

Le risposte della psichiatra e psicoterapeuta alle domande online di consulenza psicologica

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daparox e sonnolenza

07/03/2014 ore: 17.13 - stefania vaccari ha scritto:

Buongiorno, assumo daparox 20 mg da 5 Settimane ( dopo un inizio molto graduale), sto molto meglio come ansia e agorafobia, e attacchi di panico, tuttavia presento una certa sonnolenza e stanchezza soprattutto al mattino. ( il farmaco lo assumo dopo pranzo); vorrei sapere se e un effetto tipico della paroxetina e quindi se fastidioso per me dovrei cambiare molecola, oppure se col tempo passera. Ho fatto molta fatica ad abituarmi, notevoli gli eff coll inziali, ma mi dispiacerebbe ora cambiare di nuovo. E' un sintomo che puo ancora ridursi da solo o no? Non prendo piu ansiolitici da due settimane. non ne sento piu il bisogno e di notte dormo bene senza niente. L'astenia che sento, e sempre dovuta al farmaco? grazie

07/03/2014 ore: 20.32 - Dr. Raffaella Salmoria ha scritto:

Gentile Stefania, La paroxetina si distingue dagli altri antidepressivi per il suo spiccato effetto ansiolitico, che la rende farmaco ideale nel trattamento del disturbo d'attacchi di panico con o senza agorafobia. Questo profilo clinico che la mecola ha evidenziato, si traduce in un senso di "rilassatezza" od "ovattamento", utizzando le parole dei pazienti che la assumono. La sonnolenza o addirittura una leggera sedazione. invece, rappresentano effetti collaterali tipici delle prime tre settimane dall'inizio del trattamento, e sono quindi destinati a scomparire. Proseguirei nel suo caso con tutta tranquillita ad assumere il farmaco, che rappresenta tuttora la prima scelta nella cura degli attacchi di panico, con una efficacia assai alta. Cordiali saluti Dr. Raffaella Salmoria

15/02/2016 ore: 16.49 - martinotti davide ha scritto:

sono 15g che assumo daparox 5gocce al mattino 4al pomeriggio e 3 alla sera sta andando meglio come ansia pero oggi non sono andato al lavoro e tutto il giorno mi viene da dormire e stanotte ho avuto ansia forte e tacchicardia cosa posso fare?

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Buy Algisedal Online Without Prescriptions, Algisedal

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What is Algisedal?

The medicine represents the analgesics preparations group, demonstrating comprehensive efficacy in treatment of painful sensations of various nature, painful periods and mild pain associated with arthritis. A true to the type representative of benzene and substituted derivatives-type of meds, the remedy has become available in November, 1968 after a Food and Drug Administration affirmation. Since then Algisedal has rapidly received popularity across the US; the demand has given birth to a line-up of generic alternatives, e. g. generic Anacin. According to FDA license the preparation is available over the counter. Based on acetaminophen active ingredient, produced and initially recorded to Polymedica, the medicine is basically created for oral use, and comes as suspension. Conforming to Canadian DrugBank directory stats as for November, 1968, the pricing for acetaminophen-based meds starts from $0.01 and reaches $2.77 per unit (please, note that our platform doesn’t offer Algisedal and the values are displayed for info purposes only). The remedy is mass-produced all around the world by the leading pharmaceutical corporations, such as Able Laboratories Inc. On the grounds of Algisedal treatment course reviews by verified WebMD. com users, the medication is rated 8.4 out of 10. Algisedal formula

How it works?

Algisedal is created to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Algisedal may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Algisedal is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body.

Dosage & administration

Before you consume Algisedal, please, read the prescribing information. If you have doubts as for drug interactions or any other aspect of Algisedal treatment, you must seek for professional assistance before using the drug. Consult your physician to select an optimum administration regimen.

Side effects

Apart from a long range of positive effects, the great majority of meds cause unwanted adverse reactions, although the frequency of cases generally doesn’t go beyond 9% level. Indicated below is the list of the most widespread adverse reactions as stated at NCBI portal, based on 69 clinical researches and reviews:

unusual bleeding or bruising

pinpoint red spots on the – 3.1%

ulcers – 2.9%

or itching – 3.1%

hives – 2.9%

sudden decrease in the amount of urine – 2.7%

skin rash – 3.3%

sore throat – not present before treatment and not caused by the condition being treated – 3.1%

or white spots on the lips or in the mouth – 3.1%

If one or several indicated adverse effects last long, you should seek for medical attention immediately to avoid any complications. Not listed side effects can be reported to FDA via the phone: 1-800-FDA-1088.

Contraindications

Not all the meds are suitable for those having certain conditions, and it may turn out that a drug can only be applied if extra care is taken. For this reason, before you start taking Algisedal, consult treating physician how to take the drug in case of any diseases.

Review

Jacqueline Raye, 54, Warren, USA I have been applying Algisedal for a couple of weeks, and indeed its effect is second to none. My therapist has warned me about the possible or white spots on the lips or in the mouth and sudden decrease in the amount of urine because in my situation it was a prolonged recovery treatment. Even though I had to adjust the dosage, the treatment course was a great success. Oh yeah, Surprisingly, but it seems like Algisedal in its generic form (generic Anacin) is a no less efficient medication. You should surely turn it into account. Rahul Pahuja, 39, New York, USA I’ve bought Anacin by recommendation of my therapist – impressed by the drug’s treatment capabilities, I’ve bought Anacin online and initiated in the treatment course. Actually, I didn’t expect the effect would be that strong; with a higher dosage I’ve never suffered from neither or itching nor pinpoint red spots on the. Kristen Horton, 43, Anchorage, USA Anacin is probably the best preparation that has helped me to eliminate painful periods quickly and effectively. With the starting from just $0.01 and incredible effect, this is the best you can get.

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Epimil (Lamictal) Explicacion

Epimil es realmente una medicina senalo en relacion con el tratamiento complementario con respecto a la infancia utilizando los tipos siguientes de incautacion por ejemplo convulsiones incompletas, principales convulsiones tonico-clonicas generales, convulsiones generales asociadas al sindrome de Lennox sintomas - Gastaut; monoterapia con respecto a madurar a lo largo de los enfermos con convulsiones incompletas que estan recibiendo, ademas, su propia terapia junto con la carbamazepina, fenitoina, fenobarbital, primidona, asi como valproato; bipolar terapia grupos de apoyo con respecto a los adultos. Epimil le ayuda a manejar los ataques de sentimientos (depresion, odio, hipomania, asi como episodios combinados).

Epimil sigue siendo un impacto asociado con las estaciones de sal. Por lo tanto, Epimil mantiene lejos estaciones de sal respaldo paredes ansiosos, asi como hereupon regulan presinaptica todo eso lanzamiento asociado con proteinas excitatorias.

Epimil tambien puede ser referido como lamotrigina, Lametec.

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Epimil (Lamictal) Dosis

Epimil viene en:

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50 mg de material Regular friccion Dosis

100mg Mejora de material de friccion Dosis

Llevelo por via oral.

Epimil puede utilizarse a traves de los adultos y los ninos.

Si usted desea lograr mejores resultados por lo general no dejar de usar Epimil de repente.

Epimil (Lamictal) Careciendo asocia con dosis

Por lo general, no reciben doble dosis. En caso de que salte la dosis que necesita para llevar una vez se tiene en cuenta en lo que respecta a su deficiente. Cuando es hora de la dosis que necesita para llevar a cabo su propia rutina de dosificacion normal.

Epimil (Lamictal)

En el caso de que una sobredosis de Epimil y que tambien se evita gran usted necesita comprobar hacia fuera su medico o incluso el medico de inmediato. Asociado con la sobredosis de Epimil: ataxia, nistagmus, la mejora de las convulsiones, disminucion de grado de conciencia, coma, fianza intraventricular mantener a raya.

Epimil (Lamictal) Espacio de almacenamiento

Tienda en temperaturas de espacio entre 10 y 30 niveles de D (59, asi como ochenta y seis niveles F) de humedad, asi como la temperatura. Fortalecer cualquier tipo de medicamento sin tocar a partir del dia de vencimiento. Mantener colocado de forma segura fuera del camino de los ninos.

Epimil (Lamictal) Efectos negativos

Epimil ofrece los efectos negativos. El mas tipico tienden a ser:

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Negativa Efectos indicaciones son dependen de la medicacion que pueda estar utilizando, pero, ademas, confiar en su condicion de bienestar y otros aspectos.

Epimil (Lamictal) Contraindicaciones

Por lo general no reciben Epimil en caso de que son sensibles con el fin de elementos Epimil.

Tenga cuidado junto con Epimil en caso de que usted esta esperando, van a quedar embarazada, y / o en periodo de lactancia.

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Epimil (Lamictal) Preguntas comunes

Queen: ?Que es exactamente se utiliza para Epimil?

El: Epimil es realmente una medicina senalo en relacion con el tratamiento complementario con respecto a la infancia utilizando los tipos de convulsiones posteriores: incompleto convulsiones. principal general, tonico-clonicas convulsiones. en general convulsiones asociado con sintomas de Lennox-Gastaut; monoterapia con respecto a madurar a lo largo de los enfermos con incompletos convulsiones que estan recibiendo, ademas, su propia terapia junto con la carbamazepina, fenitoina, fenobarbital, primidona, asi como valproato; bipolar terapia grupos de apoyo con respecto a los adultos. Epimil le ayuda a manejar los ataques de sentimientos ( trastornos depresivos. odio, hipomania y episodios combinados).A

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The Lacs (Featuring Sarah Ross)- ReLacs

Опубликовано: 19 авг. 2013 г.

Off The Lacs album "Keep It Redneck" produced by Average Joes Entertainment. I own nothing.

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Aclene - Pills Blog, Aclene

Description

Differin is used for treating severe acne.

Active Ingredient: Adapalene

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Aclo Forte (100 500 15) Tablet - Drug List A

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Read about what are the Aclo Forte (100+500+15) Tablet medicine side effects, how and when to use Aclo Forte (100+500+15) Tablet, common indications of Aclo Forte (100+500+15) Tablet, when not to use Aclo Forte (100+500+15) Tablet (contra indications), manufacturer, price and generic molecules.

Aclo Forte (100+500+15) - Aceclofenac - Tablet is manufactured by Ambic Aayurchem and the main constituent generic drug is Aceclofenac - 100 mg.

Aclo Forte (100+500+15) Tablet Medicine Side effects and usage Side Effects

Indigestion, heartburn, dyspepsia, diarrhoea, nausea, abdominal pain and flatulence.

For the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Hypersensitivity. GI bleeding. Moderate to severe renal impairment. Last three months of pregnancy.

Patients with GI disease, history of peptic ulceration, cerebrovascular bleeding, ulcerative colitis. Crohns disease, systemic lupus erythmatosus, porphyria, haematopoietic or coagulation disorders. The dose should be reduced in patients with mild to moderate hepatic, renal or cardiac function impairment.

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Aclo Forte (100+500+15) Tablet mainly contains the generic formulation called as Aceclofenac - 100 mg.

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Medicine Name: Aclo Forte (100+500+15) Tablet Manufacturer: Ambic Aayurchem Generic Molecule: Aceclofenac

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A-Cnotren Drug Information, Indications - Other Medicaments on

A-Cnotren Drug Information A-Cnotren forms, composition and dosages: Indications, usages and classification codes:

There is an additional general information about this medication active ingredient isotretinoin:

Isotretinoin is an pharmaceutical agent for the treatment of acne. Contributes to the normalization of terminal cell differentiation, inhibits the hyperproliferation of the epithelium of excretory ducts of the sebaceous glands, the formation of detritus and makes it easier to evacuate. Due to this reduced production of sebum and facilitates its isolation, normal structure, decreasing the inflammatory reaction around the glands. For external and systemic application isotretinoin has antiseborrhea, sebostatic, anti-inflammatory, keratitis and immunomodulatory actions, strengthens the processes of regeneration in the skin.

When administered orally isotretinoin is absorbed from the gastrointestinal tract, absorption may increase when taken with food. C max plasma levels reached after 1-4 hours after ingestion. Oral bioavailability is low which may be caused by parietal metabolism in the intestinal wall and the effect of "first passage" through the liver. Isotretinoin is highly bound to plasma proteins. Metabolized in the liver with the formation of the main metabolite 4-oxo-isotretinoin, also there is some isomerization of isotretinoin in tretinoin. Isotretinoin, tretinoin and its metabolites are enterohepatic recycling. The end of T1/2 of tretinoin is 10-20 hours. An equivalent amount is determined in the feces, mostly unchanged, and urine in the form of metabolites.

Why is A-Cnotren prescribed?

For oral administration: severe nodular-cystic acne especially with the localization on the body. For rectal administration: severe relapsing forms of acne, rashes associated with seborrheic process. For external use: papule-pustular acne, seborrhea, rosacea, perioral dermatitis.

Dosage and administration

For oral administration initial dose is 500 mcg / kg / day; the maximum daily dose used for a limited time and is 1 mg / kg; the maintenance dose is 0.1-1 mg / kg / day; duration of treatment is 16 weeks, a second course conducted at intervals of 8 days. Isotretinoin is taken with meals in one or more receptions. Rectal - 0.5-1 mg / kg / day, one time at night (in the supine position); course of treatment - 8-12 weeks, the intervals between courses - 1-2 months. Ointment applied thinly to the affected areas of skin 2 times / day. Duration of treatment - 4-6 weeks.

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Dermatological reactions: dry mucous membranes, skin rashes, dermatitis, pruritus, cheilitis, erythema (especially on the face), sweating, palmar-plantar desquamation and paronychia, nail dystrophy, increased proliferation of granulation tissue in the affected area, rarely - thinning hair, vasculitis, photosensitivity. Senses: conjunctivitis, photophobia, decreased night vision, corneal opacity, weakening of the hearing. CNS and peripheral nervous system: headache, rarely - depression, seizures, suicide, and in rare cases - intracranial hypertension. Digestive system: nausea, rarely - colitis, bleeding from the gastrointestinal tract, transient elevation of liver transaminases and in rare cases - hepatitis. Hematopoietic system: anemia, neutropenia, changes in platelet count, increased erythrocyte sedimentation rate. Metabolism: increased concentrations of TG and glucose. Musculoskeletal system: pain in muscles and joints, rarely - hyperostosis. Other: nasal bleeding. Rectal and topical using: 1-2 weeks of treatment may cause new eruptions, itching, swelling and redness.

Pregnancy, established and planned lactation, hypersensitivity to isotretinoin, the simultaneous use of tetracycline antibiotics. For oral administration: severe liver and/or kidney damage, hypervitaminosis A, significantly elevated levels of lipids in blood plasma, neoplasms. For rectal use - diseases of the rectum.

Using A-Cnotren during pregnancy and lactation

Isotretinoin has a pronounced teratogenic and embryotoxic action. Contraindicated in established and planned pregnancy. Contraindicated during lactation.

Rectally and topically applied with caution in liver disease, kidney disease, chronic pancreatitis, decompensation of heart function, chronic intoxication (including alcohol). Rectal and external use in a pronounced exacerbation of the reaction (on 1-2-week treatment) is recommended to cancel the medication for a few days before its decline, then therapy can be resumed. For oral administration requires regular monitoring of liver function and lipid levels in blood plasma before treatment, 1 month after initiation of therapy and then every 3 months. In diabetes, obesity, alcoholism or lipid metabolism violations recommended more frequent monitoring of laboratory parameters. In diabetes mellitus or suspected it is necessary to strictly control glucose levels in plasma. With prolonged use may develop symptoms of chronic hypervitaminosis A. During treatment or within a certain time after its completion can not be donors for women of childbearing age. During the treatment, patients should not be given UV treatment, patients should avoid direct exposure to sunlight. In the course of treatment may occur intolerance of contact lenses. Safety of children and prepubertal patients has not been established. Should avoid the simultaneous use of isotretinoin and 19-nortestosterone derivatives, particularly in patients with gynecological / endocrine diseases. Not recommended for concurrent use of other drugs with keratolytic or exfoliative properties (including other retinoids), and progesterone in the microdose (including drugs "mini-pilly").

A-Cnotren drug interactions

The action of isotretinoin is weakened by the simultaneous application of progesterone in the microdose. With the simultaneous application of isotretinoin and vitamin A may increase toxic effects. With the simultaneous application of isotretinoin and aminoglycoside antibiotics is at risk of developing intracranial hypertension.

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Malflam is a nonsteroidal anti-inflammatory drug reducing hormones that cause inflammation and pain in the body. Malflam is appointed to treat pain or inflammation caused by rheumatoid arthritis and osteoarthritis in adults, plus it is also prescribed to treat juvenile rheumatoid arthritis in children who are at least 2 years old.

Dosage & administration

Before you administer Malflam, please, read the instructions for use. If you concerns regarding contraindications or any other aspect of Malflam treatment, you must seek for professional consultation prior to taking the medication. Ask your physician to pick up an optimum administration regimen.

Side effects Apart from a good number of positive effects, the vast majority of meds cause undesired side-effects, however the percentage of cases generally doesn’t go beyond 10% mark. Posted below is the list of the most widespread side effects listed at PubChem website, relying on 193 clinical researches and reviews:

infection – 9.2%

dyspepsia – 8%

upper respiratory tract infection – 3.9%

infestation nos – 8.7%

headache – 4.6%

dyspeptic signs and symptoms – 2%

influenza-like symptoms – 4.4%

nervous system disorder – 5%

gastrointestinal disorder – 4.5%

If one or several aforementioned adverse effects last and aggravate, you should seek for medical attention immediately to avoid any complications. Any adverse reactions can be reported to FDA via the phone: 1-800-FDA-1088.

Some medicines are not suitable for people with certain conditions, and it may turn out that a drug can only be used if extra care is taken. For these reasons, before you start receiving Malflam, visit your treating physician how to take the drug in case of any diseases.

Turbo Burnett, 44, Jackson, USA

I have been applying Malflam for almost 2 weeks, and indeed its effect is incredible. My treating doctor has warned me about the potential infestation nos and infection because in my case it was a complex treatment. Even though I had to change the dosage, the treatment course was a great success. Oh yeah, Surprisingly, but it seems like Malflam in its generic form (Meloxicam) is a no less effective preparation. You should certainly check it out. Kevin Hayes, 46, Kansas City, USA I’ve got Mobic by recommendation of my close friend – excited by the drug’s treatment capabilities, I’ve bought Mobic online and initiated in the treatment course. Frankly speaking, I didn’t expect the effect would be so well-pronounced; despite of a higher dose I’ve never been experiencing neither dyspeptic signs and symptoms nor influenza-like symptoms. Jessica Foley, 44, Anchorage, USA Mobic seems to be the most powerful med that has helped me to get rid of rheumatoid arthritis quickly and effectively. With the price starting from as little as $3.23 and truly impressive effect, just go for it.

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Store Anacin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Anacin out of the reach of children and away from pets.

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Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate). This includes any medicines that contain caffeine.

Anacin has aspirin in it. Before you start any new medicine, check the label to see if it has aspirin in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Talk to your doctor before you take Anacin or other pain relievers/fever reducers if you drink more than 3 drinks with alcohol per day. Serious stomach ulcers or bleeding can occur with the use of Anacin. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Anacin with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Taking more than the recommended dose or taking Anacin regularly may be habit-forming.

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Aspirin has been linked to a serious illness called Reye syndrome. Do not give Anacin to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.

Diabetes patients - Anacin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

If Anacin has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.

Tell your doctor or dentist that you take Anacin before you receive any medical or dental care, emergency care, or surgery.

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you are allergic to any ingredient in Anacin

you are a child or teenager with influenza (flu) or chickenpox

you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets, or you have active severe bleeding

you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin, tartrazine, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)

you are taking anticoagulants (eg, heparin, warfarin) or methotrexate

Before using Anacin:

Some medical conditions may interact with Anacin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have alcoholism or if you consume 3 or more alcohol-containing drinks every day

if you have asthma, bleeding or clotting problems, growths in the nose (nasal polyps), kidney or liver problems, stomach or intestinal problems (eg, ulcer, inflammation), heart problems, heartburn, upset stomach, stomach pain, hives, influenza (flu) or chickenpox, or vitamin K deficiency

if you have anxiety, trouble sleeping, or heart problems

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Some MEDICINES MAY INTERACT with Anacin. Tell your health care provider if you are taking any other medicines.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Anacin while you are pregnant. Anacin is not recommended during the last 3 months (third trimester) of pregnancy because it may cause harm to the fetus. Anacin is found in breast milk. If you are or will be breast-feeding while you use Anacin, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects. Anacin's side effects may include dizziness, heartburn, irritability, nausea, nervousness, rashes, hives, bloody stools, drowsiness, hearing loss, ringing in the ears, and trouble sleeping.

Check with your doctor if any of the listed above most COMMON side effects persist or become bothersome.

Seek medical attention right away if any of these SEVERE side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; diarrhea; drowsiness; hearing loss; ringing in the ears; severe or persistent dizziness; severe or persistent stomach pain or heartburn; shakiness; trouble sleeping; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.

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Lidocaine - Fda Prescribing Information, Side Effects And Uses, Lidocain

Lidocaine

For Infiltration and Nerve Block Including Caudal and Epidural Use.

Lidocaine Description

Lidocaine hydrochloride injection, USP is sterile, nonpyrogenic, aqueous solution that contains a local anesthetic agent and is administered parenterally by injection. See INDICATIONS for specific uses .

Lidocaine hydrochloride injection, USP contains Lidocaine hydrochloride, which is chemically designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride and has the molecular weight 270.8. Lidocaine hydrochloride (C 14 H 22 N 2 O • HCl) has the following structural formula:

Lidocaine hydrochloride injection, USP is a sterile, nonpyrogenic, isotonic solution containing sodium chloride. The pH of the solution is adjusted to approximately 6.5 (5.0−7.0) with sodium hydroxide and/or hydrochloric acid.

Lidocaine - Clinical Pharmacology

Mechanism of Action

Lidocaine hydrochloride stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action.

Hemodynamics

Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system, and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.

Pharmacokinetics and Metabolism

Information derived from diverse formulations, concentrations and usages reveals that Lidocaine hydrochloride is completely absorbed following parenteral administration, its rate of absorption depending, for example, upon various factors such as the site of administration and the presence or absence of a vasoconstrictor agent. Except for intravascular administration, the highest blood levels are obtained following intercostal nerve block and the lowest after subcutaneous administration.

The plasma binding of Lidocaine hydrochloride is dependent on drug concentration, and the fraction bound decreases with increasing concentration. At concentrations of 1 to 4 mcg of free base per mL 60 to 80 percent of Lidocaine hydrochloride is protein bound. Binding is also dependent on the plasma concentration of the alpha-1-acid glycoprotein.

Lidocaine hydrochloride crosses the blood-brain and placental barriers, presumably by passive diffusion.

Lidocaine hydrochloride is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine hydrochloride. Approximately 90% of Lidocaine hydrochloride administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.

The elimination half-life of Lidocaine hydrochloride following an intravenous bolus injection is typically 1.5 to 2 hours. Because of the rapid rate at which Lidocaine hydrochloride is metabolized, any condition that affects liver function may alter Lidocaine hydrochloride kinetics. The half-life may be prolonged two-fold or more in patients with liver dysfunction. Renal dysfunction does not affect Lidocaine hydrochloride kinetics but may increase the accumulation of metabolites.

Factors such as acidosis and the use of CNS stimulants and depressants affect the CNS levels of Lidocaine hydrochloride required to produce overt systemic effects. Objective adverse manifestations become increasingly apparent with increasing venous plasma levels above 6 mcg free base per mL. In the rhesus monkey arterial blood levels of 18 to 21 mcg/mL have been shown to be threshold for convulsive activity.

Indications and Usage for Lidocaine

Lidocaine hydrochloride injection, USP is indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks, when the accepted procedures for these techniques as described in standard textbooks are observed.

Contraindications

Lidocaine hydrochloride is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

Warnings

Lidocaine HYDROCHLORIDE INJECTION, USP FOR INFILTRATION AND NERVE BLOCK SHOULD BE EMPLOYED ONLY BY CLINICIANS WHO ARE WELL VERSED IN DIAGNOSIS AND MANAGEMENT OF DOSE-RELATED TOXICITY AND OTHER ACUTE EMERGENCIES THAT MIGHT ARISE FROM THE BLOCK TO BE EMPLOYED AND THEN ONLY AFTER ENSURING THE IMMEDIATE AVAILABILITY OF OXYGEN, OTHER RESUSCITATIVE DRUGS, CARDIOPULMONARY EQUIPMENT AND THE PERSONNEL NEEDED FOR PROPER MANAGEMENT OF TOXIC REACTIONS AND RELATED EMERGENCIES. (See also ADVERSE REACTIONS and PRECAUTIONS .) DELAY IN PROPER MANAGEMENT OF DOSE-RELATED TOXICITY, UNDERVENTILATION FROM ANY CAUSE AND/OR ALTERED SENSITIVITY MAY LEAD TO THE DEVELOPMENT OF ACIDOSIS, CARDIAC ARREST AND, POSSIBLY, DEATH.

Intra-articular infusions of local anesthetics following arthroscopic and other surgical procedures is an unapproved use, and there have been postmarketing reports of chondrolysis in patients receiving such infusions. The majority of reported cases of chondrolysis have involved the shoulder joint; cases of gleno-humeral chondrolysis have been described in pediatric and adult patients following intra-articular infusions of local anesthetics with and without epinephrine for periods of 48 to 72 hours. There is insufficient information to determine whether shorter infusion periods are not associated with these findings. The time of onset of symptoms, such as joint pain, stiffness and loss of motion can be variable, but may begin as early as the 2 nd month after surgery. Currently, there is no effective treatment for chondrolysis; patients who experienced chondrolysis have required additional diagnostic and therapeutic procedures and some required arthroplasty or shoulder replacement.

To avoid intravascular injection, aspiration should be performed before the local anesthetic solution is injected. The needle must be repositioned until no return of blood can be elicited by aspiration. Note, however, that the absence of blood in the syringe does not guarantee that intravascular injection has been avoided.

Precautions

General

The safety and effectiveness of Lidocaine hydrochloride depend on proper dosage, correct technique, adequate precautions, and readiness for emergencies. Standard textbooks should be consulted for specific techniques and precautions for various regional anesthetic procedures.

Resuscitative equipment, oxygen, and other resuscitative drugs should be available for immediate use. (See WARNINGS and ADVERSE REACTIONS .) The lowest dosage that results in effective anesthesia should be used to avoid high plasma levels and serious adverse effects. Syringe aspirations should also be performed before and during each supplemental injection when using indwelling catheter techniques. During the administration of epidural anesthesia, it is recommended that a test dose be administered initially and that the patient be monitored for central nervous system toxicity and cardiovascular toxicity, as well as for signs of unintended intrathecal administration, before proceeding. When clinical conditions permit, consideration should be given to employing local anesthetic solutions that contain epinephrine for the test dose because circulatory changes compatible with epinephrine may also serve as a warning sign of unintended intravascular injection. An intravascular injection is still possible even if aspirations for blood are negative. Repeated doses of Lidocaine hydrochloride may cause significant increases in blood levels with each repeated dose because of slow accumulation of the drug or its metabolites. Tolerance to elevated blood levels varies with the status of the patient. Debilitated, elderly patients, acutely ill patients, and children should be given reduced doses commensurate with their age and physical condition. Lidocaine hydrochloride should also be used with caution in patients with severe shock or heart block.

Lumbar and caudal epidural anesthesia should be used with extreme caution in persons with the following conditions: existing neurological disease, spinal deformities, septicemia, and severe hypertension.

Local anesthetic solutions containing a vasoconstrictor should be used cautiously and in carefully circumscribed quantities in areas of the body supplied by end arteries or having otherwise compromised blood supply. Patients with peripheral vascular disease and those with hypertensive vascular disease may exhibit exaggerated vasoconstrictor response. Ischemic injury or necrosis may result. Preparations containing a vasoconstrictor should be used with caution in patients during or following the administration of potent general anesthetic agents, since cardiac arrhythmias may occur under such conditions.

Careful and constant monitoring of cardiovascular and respiratory (adequacy of ventilation) vital signs and the patient’s state of consciousness should be accomplished after each local anesthetic injection. It should be kept in mind at such times that restlessness, anxiety, tinnitus, dizziness, blurred vision, tremors, depression or drowsiness may be early warning signs of central nervous system toxicity.

Since amide-type local anesthetics are metabolized by the liver, Lidocaine hydrochloride injection, USP should be used with caution in patients with hepatic disease. Patients with severe hepatic disease, because of their inability to metabolize local anesthetics normally, are at greater risk of developing toxic plasma concentrations. Lidocaine hydrochloride injection, USP should also be used with caution in patients with impaired cardiovascular function since they may be less able to compensate for functional changes associated with the prolongation of A-V conduction produced by these drugs.

Many drugs used during the conduct of anesthesia are considered potential triggering agents for familial malignant hyperthermia. Since it is not known whether amide-type local anesthetics may trigger this reaction and since the need for supplemental general anesthesia cannot be predicted in advance, it is suggested that a standard protocol for the management of malignant hyperthermia should be available. Early unexplained signs of tachycardia, tachypnea, labile blood pressure and metabolic acidosis may precede temperature elevation. Successful outcome is dependent on early diagnosis, prompt discontinuance of the suspect triggering agent(s) and institution of treatment, including oxygen therapy, indicated supportive measures and dantrolene (consult dantrolene sodium intravenous package insert before using).

Proper tourniquet technique, as described in publications and standard textbooks, is essential in the performance of intravenous regional anesthesia. Solutions containing epinephrine or other vasoconstrictors should not be used for this technique.

Lidocaine hydrochloride should be used with caution in persons with known drug sensitivities. Patients allergic to para-aminobenzoic acid derivatives (procaine, tetracaine, benzocaine, etc.) have not shown cross sensitivity to Lidocaine hydrochloride.

Use in the Head and Neck Area

Small doses of local anesthetics injected into the head and neck area, including retrobulbar, dental and stellate ganglion blocks, may produce adverse reactions similar to systemic toxicity seen with unintentional intravascular injections of larger doses. Confusion, convulsions, respiratory depression and/or respiratory arrest, and cardiovascular stimulation or depression have been reported. These reactions may be due to intra-arterial injection of the local anesthetic with retrograde flow to the cerebral circulation. Patients receiving these blocks should have their circulation and respiration monitored and be constantly observed. Resuscitative equipment and personnel for treating adverse reactions should be immediately available. Dosage recommendations should not be exceeded. (See DOSAGE AND ADMINISTRATION. )

Information for Patients

When appropriate, patients should be informed in advance that they may experience temporary loss of sensation and motor activity, usually in the lower half of the body, following proper administration of epidural anesthesia.

Clinically Significant Drug Interactions

The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension.

Phenothiazines and butyrophenones may reduce or reverse the pressor effect of epinephrine.

Concurrent use of these agents should generally be avoided. In situations when concurrent therapy is necessary, careful patient monitoring is essential.

Concurrent administration of vasopressor drugs (for the treatment of hypotension related to obstetric blocks) and ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular accidents.

Drug/Laboratory Test Interactions

The intramuscular injection of Lidocaine hydrochloride may result in an increase in creatine phosphokinase levels. Thus, the use of this enzyme determination, without isoenzyme separation, as a diagnostic test for the presence of acute myocardial infarction may be compromised by the intramuscular injection of Lidocaine hydrochloride.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Studies of Lidocaine hydrochloride in animals to evaluate the carcinogenic and mutagenic potential or the effect on fertility have not been conducted.

Pregnancy

Pregnancy Category B

Reproduction studies have been performed in rats at doses up to 6.6 times the human dose and have revealed no evidence of harm to the fetus caused by Lidocaine hydrochloride. There are, however, no adequate and well-controlled studies in pregnant women. Animal reproduction studies are not always predictive of human response. General consideration should be given to this fact before administering Lidocaine hydrochloride to women of childbearing potential, especially during early pregnancy when maximum organogenesis takes place.

Labor and Delivery

Local anesthetics rapidly cross the placenta and when used for epidural, paracervical, pudendal or caudal block anesthesia, can cause varying degrees of maternal, fetal and neonatal toxicity. (See CLINICAL PHARMACOLOGY: Pharmacokinetics. ) The potential for toxicity depends upon the procedure performed, the type and amount of drug used, and the technique of drug administration. Adverse reactions in the parturient, fetus and neonate involve alterations of the central nervous system, peripheral vascular tone and cardiac function.

Maternal hypotension has resulted from regional anesthesia. Local anesthetics produce vasodilation by blocking sympathetic nerves. Elevating the patient’s legs and positioning her on her left side will help prevent decreases in blood pressure.

The fetal heart rate also should be monitored continuously, and electronic fetal monitoring is highly advisable.

Epidural, spinal, paracervical, or pudendal anesthesia may alter the forces of parturition through changes in uterine contractility or maternal expulsive efforts. In one study, paracervical block anesthesia was associated with a decrease in the mean duration of first stage labor and facilitation of cervical dilation. However, spinal and epidural anesthesia have also been reported to prolong the second stage of labor by removing the parturient’s reflex urge to bear down or by interfering with motor function. The use of obstetrical anesthesia may increase the need for forceps assistance.

The use of some local anesthetic drug products during labor and delivery may be followed by diminished muscle strength and tone for the first day or two of life. The long-term significance of these observations is unknown. Fetal bradycardia may occur in 20 to 30 percent of patients receiving paracervical nerve block anesthesia with the amide-type local anesthetics and may be associated with fetal acidosis. Fetal heart rate should always be monitored during paracervical anesthesia. The physician should weigh the possible advantages against risks when considering a paracervical block in prematurity, toxemia of pregnancy, and fetal distress. Careful adherence to recommended dosage is of the utmost importance in obstetrical paracervical block. Failure to achieve adequate analgesia with recommended doses should arouse suspicion of intravascular or fetal intracranial injection. Cases compatible with unintended fetal intracranial injection of local anesthetic solution have been reported following intended paracervical or pudendal block or both. Babies so affected present with unexplained neonatal depression at birth, which correlates with high local anesthetic serum levels, and often manifest seizures within six hours. Prompt use of supportive measures combined with forced urinary excretion of the local anesthetic has been used successfully to manage this complication.

Case reports of maternal convulsions and cardiovascular collapse following use of some local anesthetics for paracervical block in early pregnancy (as anesthesia for elective abortion) suggest that systemic absorption under these circumstances may be rapid. The recommended maximum dose of each drug should not be exceeded. Injection should be made slowly and with frequent aspiration. Allow a 5-minute interval between sides.

Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Lidocaine hydrochloride is administered to a nursing woman.

Pediatric Use

Dosages in children should be reduced, commensurate with age, body weight and physical condition. (See DOSAGE AND ADMINISTRATION .)

Adverse Reactions

Systemic

Adverse experiences following the administration of Lidocaine hydrochloride are similar in nature to those observed with other amide local anesthetic agents. These adverse experiences are, in general, dose-related and may result from high plasma levels caused by excessive dosage, rapid absorption or inadvertent intravascular injection, or may result from a hypersensitivity, idiosyncrasy or diminished tolerance on the part of the patient. Serious adverse experiences are generally systemic in nature. The following types are those most commonly reported:

CNS manifestations are excitatory and/or depressant and may be characterized by lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest. The excitatory manifestations may be very brief or may not occur at all, in which case the first manifestation of toxicity may be drowsiness merging into unconsciousness and respiratory arrest.

Drowsiness following the administration of Lidocaine hydrochloride is usually an early sign of a high blood level of the drug and may occur as a consequence of rapid absorption.

Cardiovascular manifestations are usually depressant and are characterized by bradycardia, hypotension, and cardiovascular collapse, which may lead to cardiac arrest.

Allergic reactions are characterized by cutaneous lesions, urticaria, edema or anaphylactoid reactions. Allergic reactions may occur as a result of sensitivity to local anesthetic agents. Allergic reactions as result of sensitivity to Lidocaine hydrochloride are extremely rare and, if they occur, should be managed by conventional means. The detection of sensitivity by skin testing is of doubtful value.

The incidences of adverse reactions associated with the use of local anesthetics may be related to the total dose of local anesthetic administered and are also dependent upon the particular drug used, the route of administration and the physical status of the patient. In a prospective review of 10,440 patients who received Lidocaine hydrochloride for spinal anesthesia, the incidences of adverse reactions were reported to be about 3 percent each for positional headaches, hypotension and backache; 2 percent for shivering; and less than 1 percent each for peripheral nerve symptoms, nausea, respiratory inadequacy and double vision. Many of these observations may be related to local anesthetic techniques, with or without a contribution from the local anesthetic.

In the practice of caudal or lumbar epidural block, occasional unintentional penetration of the subarachnoid space by the catheter may occur. Subsequent adverse effects may depend partially on the amount of drug administered subdurally. These may include spinal block of varying magnitude (including total spinal block), hypotension secondary to spinal block, loss of bladder and bowel control, and loss of perineal sensation and sexual function. Persistent motor, sensory and/or autonomic (sphincter control) deficit of some lower spinal segments with slow recovery (several months) or incomplete recovery have been reported in rare instances when caudal or lumbar epidural block has been attempted. Backache and headache have also been noted following use of these anesthetic procedures.

There have been reported cases of permanent injury to extraocular muscles requiring surgical repair following retrobulbar administration.

Overdosage

Acute emergencies from local anesthetics are generally related to high plasma levels encountered during therapeutic use of local anesthetics or to unintended subarachnoid injection of local anesthetic solution (see ADVERSE REACTIONS. WARNINGS. and PRECAUTIONS ).

Management of Local Anesthetic Emergencies

The first consideration is prevention best accomplished by careful and constant monitoring of cardiovascular and respiratory vital signs and the patient’s state of consciousness after each local anesthetic injection. At the first sign of change, oxygen should be administered.

The first step in the management of convulsions, as well as underventilation or apnea due to unintended subarachnoid injection of drug solution, consists of immediate attention to the maintenance of a patent airway and assisted or controlled ventilation with oxygen and a delivery system capable of permitting immediate positive airway pressure by mask. Immediately after the institution of these ventilatory measures, the adequacy of the circulation should be evaluated, keeping in mind that drugs used to treat convulsions sometimes depress the circulation when administered intravenously. Should convulsions persist despite adequate respiratory support, and if the status of the circulation permits, small increments of an ultra-short acting barbiturate (such as thiopental or thiamylal) or a benzodiazepine (such as diazepam) may be administered intravenously. The clinician should be familiar, prior to the use of local anesthetics, with these anticonvulsant drugs. Supportive treatment of circulatory depression may require administration of intravenous fluids and, when appropriate, a vasopressor as directed by the clinical situation (e. g. ephedrine).

If not treated immediately, both convulsions and cardiovascular depression can result in hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest. Underventilation or apnea due to unintentional subarachnoid injection of local anesthetic solution may produce these same signs and also lead to cardiac arrest if ventilatory support is not instituted. If cardiac arrest should occur, standard cardiopulmonary resuscitative measures should be instituted.

Endotracheal intubation, employing drugs and techniques familiar to the clinician, may be indicated, after initial administration of oxygen by mask, if difficulty is encountered in the maintenance of a patent airway or if prolonged ventilatory support (assisted or controlled) is indicated.

Dialysis is of negligible value in the treatment of acute overdosage with Lidocaine hydrochloride. The oral LD 50 of Lidocaine hydrochloride in non-fasted female rats is 459 (346 to 773) mg/kg (as the salt) and 214 (159 to 324) mg/kg (as the salt) in fasted female rats.

Lidocaine Dosage and Administration

Table 1 (Recommended Dosages) summarizes the recommended volumes and concentrations of Lidocaine hydrochloride injection, USP for various types of anesthetic procedures. The dosages suggested in this table are for normal healthy adults and refer to the use of epinephrine-free solutions. When larger volumes are required, only solutions containing epinephrine should be used except in those cases where vasopressor drugs may be contraindicated.

There have been adverse event reports of chondrolysis in patients receiving intra-articular infusions of local anesthetics following arthroscopic and other surgical procedures. Lidocaine hydrochloride injection, USP is not approved for this use (see WARNINGS and DOSAGE AND ADMINISTRATION ).

These recommended doses serve only as a guide to the amount of anesthetic required for most routine procedures. The actual volumes and concentrations to be used depend on a number of factors such as type and extent of surgical procedure, depth of anesthesia and degree of muscular relaxation required, duration of anesthesia required, and the physical condition of the patient. In all cases the lowest concentration and smallest dose that will produce the desired result should be given. Dosages should be reduced for children and for the elderly and debilitated patients and patients with cardiac and/or liver disease.

The onset of anesthesia, the duration of anesthesia and the degree of muscular relaxation are proportional to the volume and concentration (i. e. total dose) of local anesthetic used. Thus, an increase in volume and concentration of Lidocaine hydrochloride injection, USP will decrease the onset of anesthesia, prolong the duration of anesthesia, provide a greater degree of muscular relaxation and increase the segmental spread of anesthesia. However, increasing the volume and concentration of Lidocaine hydrochloride injection, USP may result in a more profound fall in blood pressure when used in epidural anesthesia. Although the incidence of side effects with Lidocaine hydrochloride is quite low, caution should be exercised when employing large volumes and concentrations, since the incidence of side effects is directly proportional to the total dose of local anesthetic agent injected.

Epidural Anesthesia

For epidural anesthesia the following dosage form of Lidocaine hydrochloride injection, USP is recommended:

1% without epinephrine 30 mL single dose vials

Although this solution is intended specifically for epidural anesthesia, it may also be used for infiltration and peripheral nerve block, provided it is employed as a single dose unit.

This solution contains no bacteriostatic agent.

In epidural anesthesia, the dosage varies withthe number of dermatomes to be anesthetized (generally 2 to 3 mL of the indicated concentration per dermatome).

Caudal and Lumbar Epidural Block

As a precaution against the adverse experience sometimes observed following unintentional penetration of the subarachnoid space, a test dose such as 2 to 3 mL of 1.5% Lidocaine hydrochloride should be administered at least 5 minutes prior to injecting the total volume required for a lumbar or caudal epidural block. The test dose should be repeated if the patient is moved in a manner that may have displaced the catheter. Epinephrine, if contained in the test dose (10 to 15 mcg have been suggested), may serve as a warning of unintentional intravascular injection. If injected into a blood vessel, this amount of epinephrine is likely to produce a transient “epinephrine response” within 45 seconds, consisting of an increase in heart rate and systolic blood pressure, circumoral pallor, palpitations and nervousness in the unsedated patient. The sedated patient may exhibit only a pulse rate increase of 20 or more beats per minute for 15 or more seconds. Patients on beta blockers may not manifest changes in heart rate, but blood pressure monitoring can detect an evanescent rise in systolic blood pressure. Adequate time should be allowed for onset of anesthesia after administration of each test dose. The rapid injection of a large volume of Lidocaine hydrochloride injection, USP through the catheter should be avoided, and, when feasible, fractional doses should be administered.

In the event of the known injection of a large volume of local anesthetic solution into the subarachnoid space, after suitable resuscitation and if the catheter is in place, consider attempting the recovery of drug by draining a moderate amount of cerebrospinal fluid (such as 10 mL) through the epidural catheter.

MAXIMUM RECOMMENDED DOSAGES

NOTE: The products accompanying this insert do not contain epinephrine.

Adults

For normal healthy adults, the individual maximum recommended dose of Lidocaine hydrochloride with epinephrine should not exceed 7 mg/kg (3.5 mg/lb) of body weight, and in general it is recommended that the maximum total dose not exceed 500 mg. When used without epinephrine the maximum individual dose should not exceed 4.5 mg/kg (2 mg/lb) of body weight, and in general it is recommended that the maximum total dose does not exceed 300 mg. For continuous epidural or caudal anesthesia, the maximum recommended dosage should not be administered at intervals of less than 90 minutes. When continuous lumbar or caudal epidural anesthesia is used for non-obstetrical procedures, more drug may be administered if required to produce adequate anesthesia.

The maximum recommended dose per 90 minute period of Lidocaine hydrochloride for paracervical block in obstetrical patients and non-obstetrical patients is 200 mg total. One half of the total dose is usually administered to each side. Inject slowly, five minutes between sides. (See also discussion of paracervical block in PRECAUTIONS .)

For intravenous regional anesthesia, the dose administered should not exceed 4 mg/kg in adults.

Children

It is difficult to recommend a maximum dose of any drug for children, since this varies as a function of age and weight. For children over 3 years of age who have a normal lean body mass and normal body development, the maximum dose is determined by the child’s age and weight. For example, in a child of 5 years weighing 50 lbs the dose of Lidocaine hydrochloride should not exceed 75 to 100 mg (1.5 to 2 mg/lb). The use of even more dilute solutions (i. e. 0.25 to 0.5%) and total dosages not to exceed 3 mg/kg (1.4 mg/lb) are recommended for induction of intravenous regional anesthesia in children.

In order to guard against systemic toxicity, the lowest effective concentration and lowest effective dose should be used at all times. In some cases it will be necessary to dilute available concentrations with 0.9% sodium chloride injection in order to obtain the required final concentration.

NOTE: Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever the solution and container permit. Do not use if solution is discolored or contains a precipitate.

Table 1. Recommended Dosages

Lidocaine Hydrochloride Injection, USP (without epinephrine)

THE ABOVE SUGGESTED CONCENTRATIONS AND VOLUMES SERVE ONLY AS A GUIDE. OTHER VOLUMES AND CONCENTRATIONS MAY BE USED PROVIDED THE TOTAL MAXIMUM RECOMMENDED DOSE IS NOT EXCEEDED.

STERILIZATION, STORAGE AND TECHNICAL PROCEDURES

Disinfecting agents containing heavy metals, which cause release of respective ions (mercury, zinc, copper, etc.) should not be used for skin or mucous membrane disinfection as they have been related to incidents of swelling and edema.

How is Lidocaine Supplied

Lidocaine Hydrochloride Injection USP, is supplied as follows:

Lidocaine Hydrochloride Injection USP, 1% (10 mg/mL)

2 mL Single Dose Vials in a Carton of 10 NDC 55150-161-02 5 mL Single Dose Vials in a Carton of 10 NDC 55150-162-05 30 mL Single Dose Vials in a Carton of 1 NDC 55150-163-30

Lidocaine Hydrochloride Injection USP, 2% (20 mg/mL)

2 mL Single Dose Vials in a Carton of 10 NDC 55150-164-02 5 mL Single Dose Vials in a Carton of 10 NDC 55150-165-05

The vial stopper is not made with natural rubber latex.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Manufactured for: AuroMedics Pharma LLC 6 Wheeling Road Dayton, NJ 08810

Manufactured by: Aurobindo Pharma Limited IDA, Pashamylaram - 502307 AP. India

Issued: April 2014

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 20 mg/2 mL (10 mg/mL) - 2 mL Container Label

Rx only NDC 55150-161-02 Lidocaine HYDROCHLORIDE Injection, USP 1% 20 mg/2 mL (10 mg/mL) Methylparaben Free 2 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 20 mg/2 mL (10 mg/mL) - 2 mL Container-Carton [10 Vials]

Rx only NDC 55150-161-02 Lidocaine HYDROCHLORIDE Injection, USP 1% 20 mg/2 mL (10 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 10 x 2 mL Single Dose Vials AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 50 mg/5 mL (10 mg/mL) - 5 mL Container Label

Rx only NDC 55150-162-05 Lidocaine HYDROCHLORIDE Injection, USP 1% 50 mg/5 mL (10 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 5 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 50 mg/5 mL (10 mg/mL) - 5 mL Container-Carton [10 Vials]

Rx only NDC 55150-162-05 Lidocaine HYDROCHLORIDE Injection, USP 1% 50 mg/5 mL (10 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 10 x 5 mL Single Dose Vials AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 300 mg/30 mL (10 mg/mL) - 30 mL Container Label

Rx only NDC 55150-163-30 Lidocaine HYDROCHLORIDE Injection, USP 1% 300 mg/30 mL (10 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 30 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 1% 300 mg/30 mL (10 mg/mL) - 30 mL Container-Carton [1 Vial]

Rx only NDC 55150-163-30 Lidocaine HYDROCHLORIDE Injection, USP 1% 300 mg/30 mL (10 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 30 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 2% 40 mg/2 mL (20 mg/mL) - 2 mL Container Label

Rx only NDC 55150-164-02 Lidocaine HYDROCHLORIDE Injection, USP 2% 40 mg/2 mL (20 mg/mL) Methylparaben Free 2 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 2% 40 mg/2 mL (20 mg/mL) - 2 mL Container-Carton [10 Vials]

Rx only NDC 55150-164-02 Lidocaine HYDROCHLORIDE Injection, USP 2% 40 mg/2 mL (20 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 10 x 2 mL Single Dose Vials AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 2% 100 mg/5 mL (20 mg/mL) - 5 mL Container Label

Rx only NDC 55150-165-05 Lidocaine HYDROCHLORIDE Injection, USP 2% 100 mg/5 mL (20 mg/mL) For Infiltration and Nerve Block Including Caudal and Epidural Use. Methylparaben Free 5 mL Single Dose Vial AUROMEDICS

PACKAGE LABEL-PRINCIPAL DISPLAY PANEL - 2% 100 mg/5 mL (20 mg/mL) - 5 mL Container-Carton [10 Vials]

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Buy Mercilon Contraceptive Pill Online, Mercilon

Mercilon

What is Mercilon?

Mercilon is a combined contraceptive pill which contains two synthetic hormones: ethinylestradiol and desogestrel. It is an effective form of birth control.

How does Mercilon work?

Mercilon birth control works in 3 ways:

Mercilon prevents ovulation. This means that no egg is released from the ovaries, and so no fertilisation can take place.

Mercilon increases the thickness of the cervical mucus. This makes it difficult for sperm to enter the womb.

Mercilon alters the womb lining, making it too thin for an egg to become implanted in the womb, if one was released from the ovaries.

What are the advantages of Mercilon?

Similar to many of the other combined contraceptives, Mercilon can help regulate the menstrual cycle and make periods more predictable. It can also reduce any pain experienced by women when they menstruate. Mercilon might even reduce the risk of cancer of the ovaries and womb.

Can I still get pregnant in the long run?

If you are taking the pill as the instructions state, you are virtually completely protected from becoming pregnant. As the treatment is only hormonal, you can get pregnant again once you stop taking the treatment. The treatment is very reliable and reversible.

Who usually takes Mercilon?

Any woman who is over 18 and is not pregnant can take Mercilon to prevent pregnancy. As with some of the other contraceptives, Mercilon needs to be taken almost every day (every day for 21 days, starting on the first day of your period). To make the treatment work, you need to be consistent with taking the pill: some women may find this inconvenient. You should check the warnings tab to ensure that it is suitable for you to take Mercilon.

However, Mercilon is not recommended for smokers over 35 years old, and women with a body mass index (BMI) greater than 35 kg/m2.

Am I at risk of venous thromboembolism (VTE)?

Any contraception containing oestrogen increases the risk of venous thromboembolism (VTE). Studies suggest that for women who do not use contraception the risk of VTE is 5 to 50 women per year in 100,000. This risk rises two to fivefold for women who use low dose oestrogen combined oral contraceptives (COCs), to 25 to 100 women per year in 100,000. Progesterone only pills (POPs) do not increase the risk of VTE. As Mercilon contains the least oestrogen of the COCs, the increased risk of VTE is minimised.

Am I at risk of a heart attack?

No. There is no increased risk of heart attack (myocardial infarction) due to using low dose oestrogen combined contraceptives such as Mercilon.

Will my weight increase?

No. Mercilon does not cause weight gain. Weight gain was a side effect of earlier contraceptives with higher progesterone doses. The modern combined oral contraceptives (COCs) such as Marvelon, Mercilon, and Cerazette offered by DrEd contain reduced levels of progesterone, and the type of progesterone used (Desogestrel) is more targeted and does not have the side effect of weight gain.

Is there anything I can’t eat whilst taking Mercilon?

No, just maintain your current diet.

Do you need a prescription for Mercilon?

No. DrEd will send Mercilon to you after a consultation, provided Mercilon is suitable for your needs.

When should I start taking Mercilon?

You should start taking Mercilon on the first day of your period. This will continue for 21 days.

Do I still need to use a condom when taking Mercilon?

Yes. Taking a contraceptive like Mercilon does not protect you from STIs (sexually transmitted infections): a condom can prevent STI transmission. Furthermore, there is always that 1% chance that you can still get pregnant whilst taking Mercilon: using a condom is a good back up precaution.

Can I drink alcohol whilst taking Mercilon?

There is no interaction between this medication and alcohol and so it is medically acceptable to drink whilst on Mercilon. However, drinking too much alcohol can have very severe impacts on your general health and so should be avoided.

How will I know that Mercilon is working?

You do not take the pill for 7 days in your cycle (the time between the 21st day after the first day of your period and the first day of your next period). During this time, you will have a “withdrawal” bleed. This is perfectly normal and shows the contraceptive is working as it should. If you miss one of these withdrawal bleeds but have taken your pills correctly, it is unlikely you are pregnant. However, if you miss two withdrawal bleeds in a row, there is a chance you are pregnant. If this applies to you, contact a medical professional as soon as possible; they will be able to confirm whether you are pregnant or not.

What dosage do I take?

A standard Mercilon tablet contains 150mg Desogestrel and 20mg Ethinylestradiol. You should take one tablet per day, and try to set up a routine where you take this at the same time every day to make sure you don’t miss a dose. If you realise you have missed a dose too late, just resume your medication the next day. You will still be protected. However, if you miss three or more treatments, the treatment is ineffective and you can get pregnant. It doesn’t matter if you take food or don’t take food with your treatment.

Vomiting or having diarrhoea 12 hours after taking the pill may mean you are not fully protected. This case should be treated in the same way as missing a dose: resume treatment the next day, but be sure to use additional contraceptive methods just in case.

You should take Mercilon for 21 days, starting on the first day of your period. During the last 7 days of your 28-day cycle, you do not take the pill. During this time, you may experience some bleeding from the vagina: this is not a period, but just shows your body is responding to the contraceptive. The treatment is usually provided in “strips” of 21: this makes it easier for you to remember when to take your treatment.

Even if you are still having a withdrawal bleed but your 7 break days are over, you must resume taking Mercilon for the next 21 days to ensure full protection.

If you overdose, this will not improve you protection. It won’t harm you either, but may make you feel nauseous or experience vaginal bleeding, so is not advisable.

What is in a Mercilon tablet?

Mercilon tablets contain the active ingredients ethinylestradiol (20mg) and desogestrel (150mg). Mercilon tablets also contain dl-alpha-tocopherol, potato starch, povidone, stearic acid, aerosil and lactose. If you are allergic to any of these ingredients you should not take Mercilon.

Mercilon Side Effects

Migraine/headache

Weight gain

Sore breasts/nipple discharge

Depression/mood changes

Increased blood pressure (swollen feet and hands). This is rare

Gynaecological and vaginal problems: fibroids/endometriosis (womb disorders), fungal infections like thrush and changes in secretions

Withdrawal bleeds (do not worry about these, so long as they do not last over 2 days)

Rashes/brown patches on the skin may occasionally occur

Nausea/vomiting

Eye discomfort

Gall stones

Chorea (jerky movements)

Systematic Lupus Erythematosus (causes joint ache and tiredness)

The following side effects are severe and you must see a doctor immediately if you experience any of the following:

Blood Clot (symptoms: painful swelling of the leg, chest pains, laboured breathing)

Heart attack/stroke (symptoms: severe migraine, blurred/loss of vision, dizziness, fainting, seizures, weakness or numbness on one side of the body, slurred speech, sharp chest or stomach pains)

Severe allergic reaction (symptoms: swollen face, lips, mouth, tongue or throat)

Breast cancer As with all oral hormonal contraceptives, there is a slight increase (0.3%) in the risk of breast cancer (symptoms: dimpling of the skin, changes to the nipple, visible or tangible lumps in the breast tissue).

Cervical cancer A possible slight increase in risk of cervical cancer is associated with all the combined contraceptives (symptoms: vaginal discharge containing blood, vaginal bleeding, pelvic pain, painful sex).

Severe liver problems A possible slight increase in risk of liver problems is associated with all the combined contraceptives (symptoms: upper abdomen pain, jaundice (yellow eyes and skin))

Warnings

What a doctor may do before you start taking Mercilon:

Take your blood pressure

Check your family’s medical history

Examine your breasts

While you are taking Mercilon you need to:

Have regular check-ups with your doctor

Have regular cervical smear tests

Check your breasts for changes, lumps and dimpling of the skin regularly

Tell your doctor if you are taking Mercilon and need a blood test

Tell your doctor if you are on Mercilon before an operation: you may need to stop your contraceptive treatment 4-6 weeks before an operation to reduce the risk of blood clots

Which other risks are associated with taking the pill?

Mercilon may slightly increase your risk of having a blood clot. This is particularly true during the first year of treatment. Deep vein thrombosis is a clot in a leg vein. This is not always serious, but if the clot moves into the lungs it can cause chest pains, breathlessness, collapse and even death.

Of 100,000 women who are not on Mercilon, about 5 to 50 per year will have a blood clot: this rises to 25 to 100 in every 100,000 women taking Mercilon. However, as you can see from the figures, the chance of a blood clot is quite rare. Your lifestyle and other health factors, such as smoking and obesity, may be more likely to determine your risk of a blood clot.

Mercilon may increase the risk of cancer of the cervix, but this is more likely to be due to having sex without a condom, rather than Mercilon interacting with your body. To avoid this, have regular smear tests.

Mercilon may increase the risk of breast cancer slightly. You should not take Mercilon if you have or have had breast cancer. If you do not have breast cancer, the risk increases with the length of time you take Mercilon for, but returns to normal within ten years of stopping the medication.

You should see your doctor immediately if you notice any changes to your breasts.

Do not take Mercilon if the following apply to you:

You are pregnant/breast feeding

You have/have had breast cancer

You have unexplained vaginal bleeding

You have/have had severe liver disease

You are allergic to any of the ingredients in Mercilon

You or anyone in your close family has had problems with their circulation (including blood clots, heart attacks or strokes)

You had the following issues whilst pregnant or on steroids: jaundice, blister-like rash, hearing problems or systemic lupus erythematosus

You are over 50

You are under 18

You are a heavy smoker (more than 40 a day)

You should not take Mercilon if any of the above apply to you. In addition, if you experience any of the above whilst on Mercilon, consult your doctor immediately.

Some health issues may mean that Mercilon is less suitable for you, but that you can still use it.

Tell your doctor if any of the following apply to you:

You have had heart or circulation problems (e. g. blood clotting)

You have inflammatory bowel disease or ulcerative colitis

You have sickle cell anaemia

You have diabetes

You have excessive thickening of the womb lining

You have had gynaecological problems like fibroids or endometriosis

You have had kidney/liver problems or gall stones

You have had severe depression

You have/ have had epilepsy/migraines

You have brown patches on your body/face (chloasma)

You smoke

You have taken sex steroids before

You have high blood pressure

You have high blood cholesterol or a family history of this

You have gallstones

If you experience any of these after starting taking Mercilon, consult your doctor at once.

Some medicines can stop Mercilon from working properly :

Epilepsy treatments

Some antibiotics

Some sedatives (barbiturates)

St John’s Wort (herbal remedy)

Griseofulvin (antifungal)

Some laxatives/medical charcoal

Mercilon can also affect how well other medicines work. An example is diabetic medicine. You should consult your doctor if you are taking any other medication whilst taking Mercilon.

You should be over 18 if you use Mercilon.

There are no tests determining the safety of the drug in people under this age.

If you have a question about this service, please email info@dred. com with the question, and one of our doctors will get back to you within 24 hours.

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Prinivil - Blood Pressure, Lisodura

Common use Prinivil is in a group of drugs called ACE inhibitors. Prinivil is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. This medication may also be used to help protect the kidneys from damage due to diabetes.

Dosage and direction Take this medication by mouth, usually once a day or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. The recommended adult dose of Lisinopril ranges from 2.5 mg to 40 mg daily, depending on the condition being treated.

Precautions Before taking Lisinopril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (e. g. captopril, benazepril); or if you have any other allergies (including an allergic reaction after exposure to certain membranes used for blood filtering). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood levels of potassium, severe dehydration (and loss of electrolytes such as sodium), blood vessel disease (e. g. collagen vascular diseases such as lupus, scleroderma). This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Contraindications This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor immediately. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema).

Possible side effects You may experience headache, dizziness, lightheadedness, fatigue, nausea, diarrhea, dry cough or blurred vision as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, decreased sexual ability, chest pain. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: change in the amount of urine, vision changes, signs of infection (e. g. fever, chills, persistent sore throat).

Drug interaction Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. The following medications may affect how lisinopril works or increase the risk of side effects: nonsteroidal anti-inflammatory medications (NSAIDs; e. g. ibuprofen, indomethacin, naproxen) diuretics (water pills) potassium-sparing diuretics (e. g. spironolactone, amiloride, triamterene) medications that increase potassium levels (e. g. potassium supplements, salt substitutes containing potassium) medications that lower blood pressure (e. g. beta-blockers) The following medications may be affected by lisinopril or increase the risk of side effects: lithium

Missed dose If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Prinivil overdose may include feeling extremely dizzy or light-headed, or fainting.

Storage Store tablets at room temperature away from light and moisture. Storage temperature ranges differ according to different manufacturers, so consult your pharmacist for more information. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Dicoxib, Dicoxib

Dicoxib

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Celecoxib belongs to a group of non-steroidal anti-inflammatory drugs (NSAIDs). This medicine is used to treat osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms. It also helps to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.

Dosage and direction Take Celebrex by mouth with a glass of water, with or without food. Take the drug only as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you.

Precautions Before taking Celebrex tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have heart, liver or kidney problems. Avoid drinking alcohol and smoking while being treated with this medication. Caution is advised while using Celebrex by pregnant/nursing women or children. Aged people can be more sensitive to side effects of the medicine. During the pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.

Celebrex should not be used by patients having demonstrated a reaction of hypersensitivity to Baclofen.

Possible side effect The most common side effects are skin rash, itching or hives, chest pain, headache, nausea, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Drug interaction Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you used before using this medication. Celebrex can interact with: * medicines for high blood pressure; * other NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen; * aspirin and aspirin-like drugs; * warfarin. Turn to your doctor or pharmacist for more details.

Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.

Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

Storage Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from children and pets.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Celecoxib belongs to a group of non-steroidal anti-inflammatory drugs (NSAIDs). This medicine is used to treat osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms. It also helps to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.

Dosage and direction Take Celebrex by mouth with a glass of water, with or without food. Take the drug only as prescribed because dosage and schedule may vary depending on your condition and other factors. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for the medicine to help. Consult your doctor concerning proper dose for you.

Precautions Before taking Celebrex tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have heart, liver or kidney problems. Avoid drinking alcohol and smoking while being treated with this medication. Caution is advised while using Celebrex by pregnant/nursing women or children. Aged people can be more sensitive to side effects of the medicine. During the pregnancy this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.

Celebrex should not be used by patients having demonstrated a reaction of hypersensitivity to Baclofen.

Possible side effect The most common side effects are skin rash, itching or hives, chest pain, headache, nausea, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Drug interaction Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you used before using this medication. Celebrex can interact with: * medicines for high blood pressure; * other NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen; * aspirin and aspirin-like drugs; * warfarin. Turn to your doctor or pharmacist for more details.

Missed dose If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.

Overdose If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

Storage Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from children and pets.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Torsemide Oral Uses, Side Effects, Interactions, Pictures, Warnings - Dosing, Torasemida

torsemide

Uses

Torsemide is used to reduce extra fluid in the body (edema ) caused by conditions such as heart failure. liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen .

Torsemide is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.

How to use torsemide

Take this medication by mouth as directed by your doctor, with or without food, usually once daily. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day as directed. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Generally, it may take 4-6 weeks, and sometimes up to 12 weeks, before the full blood pressure - lowering effect is seen. Do not stop taking this medication without consulting your doctor.

Cholestyramine and colestipol can decrease the absorption of torsemide. If you are taking either of these drugs, separate the timing of each dose from torsemide by at least 2 hours.

Tell your doctor if your condition does not improve or if it worsens. If you are taking this medication to control high blood pressure. tell your doctor if your blood pressure readings remain high or increase.

Side Effects

Dizziness or headache may occur as your body adjusts to the medication. If either of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may cause a serious loss of body water (dehydration ) and salt/minerals. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps. weakness. unusual tiredness, confusion, severe dizziness, fainting. drowsiness, unusual dry mouth /thirst, nausea. vomiting. fast/irregular heartbeat. unusual decrease in the amount of urine.

Tell your doctor right away if any of these rare but serious side effects occur: numbness/tingling/pain/redness/swelling of the arms/legs, hearing changes (such as ringing in the ears. temporary or permanent decreased hearing/deafness ).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking torsemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, inability to make urine, gout .

If you have diabetes. torsemide may rarely affect your blood sugar level. Check your blood sugar level regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication or diet.

Torsemide may reduce the potassium level in your blood. Your doctor may instruct you to add potassium-rich foods to your diet (such as bananas, orange juice) or prescribe potassium supplements to prevent potassium loss. Ask your doctor for more details.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Severe sweating, diarrhea, or vomiting can increase the risk of dehydration. Report prolonged diarrhea or vomiting to your doctor. Follow your doctor's instructions about the amount of fluids you can drink.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the effects of this drug, especially dizziness and water/mineral loss.

During pregnancy, this drug should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

See also the How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: lithium.

Check the labels on all your medicines (such as cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure or worsen swelling (edema). Ask your pharmacist for more details.

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, severe weakness, a severe decrease in the amount of urine.

Notes

Do not share this medication with others.

Lifestyle changes that may help this medication work better include exercising, stopping smoking, reducing stress, and changing your diet. Consult your doctor for more details.

Laboratory and/or medical tests (such as kidney tests, blood mineral levels such as potassium) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

Images

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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Epadoren Syr 75mg, Epadoren

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BK76465IHM - RANITIDINE HYDROCHLORIDE

? ?????????? (ranitidine) ????? ????????? ??????????????? ?2-???????????? ??? ?????????, ?? ???? ??????? ?????. ?????????? ??? ?????? ??? ??? ???? ??? ???????? ???????? ???????, ?????????? ??? ???? ??? ??? ?????????????? ??? ?? ??? ??? ??????.

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?? ?????? ???????????? ?? ??????? ???????? ??? 300ml ??? ?? ????? ??? ???????.

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??????? ?? ?? ??? 17/5/2011 ?????? ????? ?? ?????? ??????????? ???3 ?/??? 54949 ??? ?????????? ?????? & ?????????? ??????????? ??? ??????????? ?? ?????? ??? ?????????????? ??????? ??????? ?? ?? ????? 38 ??? ?. 3918/2011 ??? ??' ?????. 2/2011 ?????? ????? ???????? ??? ??????? ??????????? ???????? ??? ?????????? ??????????, ?????????????????? ??? ?????????, ?? ?????? ??????????? A3-295 ??? 18/02/2011.

???? ????????????? ????? ??? ???? ????? ????????? ??? ????????????????? ? ?. ?.?. ???? ????? ???????? ????????????????? ? ?. ?.?. 6.5%. ???? ???????? ??? ??????? ????????? ??????????? ?. ?.?. ?? ??????? ????????? ?? ???????? ????? ????????? ???? 1,41%.

?? ????? ????? ?? ???? ??? ????????? 20/5/2011.

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?? ???????? ????? ???????????? ???? ??????????? ?????????????? (www. e-prescription. gr) ?? ?? ???????? ????????:

EPADOREN SYR 75MG/5ML FL x 300 ML

7,57 € (???????? 7,43 €)

7,57 € (???????? 7,43 €)

• ?????????? • ?????? ?????

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????????? ?????????: 08/09/2016

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?????? ??? ?????? ? ?????????? ??????? ?? ???? ?? ????????? ???? ???????? ??? ???????????? ??? ????????? ?????.

??????? ??? ?????????????? ????????? ??? ??? ??? ??????? ?? ??? 3? ?????? ??? ???????????? ????????? ?????????????? ?????????? ??? ?????????? ????????.

???????????? ?????????? ??? ??????? ???? ?????? ???????? ?????????????????? ???????? ??? ?????????? 1 ??? ?????? 12 ??? ?. 3816/2010, ???? ????? ???????????? ??? ??? ??????? ?????? ???????? ?????????? ??? ??????? ????????? ??? ????.

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?? ???????? ??????????? ??? ???? ????? ???????????:

1.0 [p:BOX]. ??? ????????? 1.0 [p:VIALGL] ??? 1.0 [p:BOX]. ??? ????????? 300.0 mL ??? 1.0 [p:VIALGL]

? ??????????? ??? ????????? ?????? ????????? ?? ????:

75.0 mg ??? 5.0 mL

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Ofloxbeta, Ofloxbeta

Otoflox

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Product Description Common use Floxin belongs to the group of anti-microbial medications called the fluoroquinolones which are synthetic broad-spectrum antibiotics. Due to their principally different mechanism of action they are active against great range of resistant microorganisms including polyresistant ones. They prevent unwinding and duplicating of bacterial DNA. Floxin is used to treat patients with infections of respiratory system (ears, throat, nose), skin, soft tissues, osteomyelitis, infectious diseases of abdomen, kidney, urinary tract, prostatitis, in gynecology, gonorrhea.

Dosage and directions Do not take Floxin with food. Dosage should be corrected for patients with severely abnormal liver or kidney function. Avoid taking of Floxin with antacids, minerals, and vitamins with iron which block the absorption of Floxin.

Avoid exposure of your body to sunlight during treatment with this drug.

Contraindications Hypersensitivity to quinolones, epilepsy, pregnancy, breastfeeding women, children and teenagers younger than 15 y. o.

Possible side effect The most frequent side effects include nausea, vomiting, diarrhea, insomnia, headache, dizziness, itching, and vaginitis in women. Rare allergic reactions may also occur (hives and anaphylaxis). Symptoms of nervous system stimulation, such as anxiety, euphoria, and hallucinations are rather rare.

Drug interaction Floxin is able to interact with caffeine, cyclosporine, theophylline (asthma), warfarin (anticoagulant), medications used to treat diabetes.

If you missed a dose take it as soon as you remember. If it is almost time of your next dose just skip it and return to your regular schedule. Never double the dose of this medication.

Overdose In case of serious and persistent drowsiness, nausea, hot or cold feeling, confusion, and slurred speech consult your doctor about medical attention.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Mibp Major Programs, Natibo

DoD Programs Keeping the Manufacturing and Industrial Base Sufficient, Stable, Competitive

Manufacturing and Industrial Base Policy (MIBP) has oversight responsibility for these Department of Defense programs that help ensure the domestic and global manufacturing and industrial base is fully capable of meeting the current and future product and service needs of the Warfighter.

The Defense Production Act (DPA) grants the President powers to ensure the availability and timely delivery of products, materials, and services to military and civilian agencies. It codifies a robust Presidential legal authority to enlist industry to give priority to national security production and provides for statutory review of foreign investment in U. S. companies.

The Defense Production Act Committee (DPAC) is an interagency body, established in 2009, to advise the President on DPA authorities and policies to ensure timely availability and delivery of industrial resources to meet national security needs. MIBP serves as the Executive Secretariat for the DPAC. A core mission of the DPAC Executive Secretariat is to provide overall policy guidance and execution of DPA authorities.

Title I: Defense Priorities and Allocations System (DPAS):

The Defense Priorities and Allocations System (DPAS) is a mechanism to assure the availability of industrial resources to meet national defense requirements and provides a framework for rapidly expanding industrial resources during national emergencies. -> Learn More About DPAS

Security of Supply:

To ensure the mutual supply of defense goods and services originating outside the United States, the DoD has entered into bilateral Security of Supply arrangements. These arrangements allow the DoD to request priority delivery for DoD contracts, subcontracts, or orders from companies in these countries. -> Learn More About Security of Supply

Title III: Expanding Production Capability and Supply:

The mission of Title III of the Defense Production Act is to create assured, affordable and commercially viable production capabilities and capacities for items essential for national defense.

Title VII: Committee on Foreign Investment in the United States (CFIUS):

Under Title VII of the Defense Production Act the President has delegated authority to review foreign acquisitions of U. S.-based firms and suspend or block them if they present credible threats to national security. -> Learn More About Title VII

The Department of Defense ManTech Program develops technologies and processes to ensure the affordable, timely production and sustainment of defense systems. -> Learn More About ManTech

Assessment of the Industrial Base:

To improve the DoD's ability to develop successful acquisition strategies and to deliver advanced capabilities to the warfighter at reasonable cost to the taxpayer, MIBP is pursuing multiple, concurrent efforts to map and better understand the entire defense industrial base. -> Learn More About S2T2

Independent Research & Development:

This page is currently under development.

North American Technology and Industrial Base Organization (NATIBO)

Promoting the U. S. and Canadian Technology and Industrial Base:

The North American Technology and Industrial Base Organization (NATIBO), is chartered to promote a cost effective, healthy technology and industrial base that is responsive to the national and economic security needs of the United States and Canada. -> Learn More About NATIBO

Victoria Clipper Ferry Schedules - Fares For Seattle Passenger Ferries, Clipper

Plan Your Trip

Schedules & Fares

2016 Passenger Only Ferry Service

Victoria Clipper passenger-only ferry service with year-round daily departures to Victoria, BC and seasonal daily departures to the San Juan Islands.

To book only the passenger ferry transportation, use the Clipper Only tab highlighted under Book Your Trip. Select your from and to cities, departure and return dates and number of passengers to begin the reservation process.

Ferry Schedule

August 22 to September 25

September 26 to October 16

October 17 to February 28, 2017*

Seattle / Victoria Round-Trip Fares

Adv. Purchase ? 7-days 2-days Adults Adults

September 6 to October 31

November 1 to February 28, 2017*

Seattle / Victoria One-Way Fares

September 6 to October 31

November 1 to February 28, 2017*

Special Victoria Origination Round-Trip Fares

August 1 to October 31

November 1 - December 31

January 1 to April 30

? 7 AND 2-DAY ADVANCE PURCHASE (AP) Round-Trip only

Adult: Rates are $10.00 higher for Saturday departures from Seattle, and Sunday departures from Victoria.

Special Victoria Origination Fares valid when originating travel in Victoria and traveling round trip, with min. two day advance purchase.

Child (1-11 yrs old) . Children pay 50% of adult fare.

PACKAGES: Children pay 50% of adult fare when booked in conjunction with an overnight package.

All fares include applicable taxes. A security fee will be added to all Seattle/Victoria fares & packages.

Non-cancelable; date, voyage restrictions may apply. Actual fares may vary based on booking and travel dates.

Group rates available for 20+ people, traveling together.

No Service December 25, 2016 and Tuesdays, Wednesdays and Thursdays from January 4 - February 9, 2017.

All rates in US Dollars.

Subject to change.

Departs Friday Harbor at 12:00 pm and returns at 2:30 pm. Please call for reservations and availability.

Whale sightings guaranteed: If you do not see whales during the Whale & Sealife Search, you will receive a coupon for a complimentary trip.

CHILDREN (1-11 yrs old) $25 with 1-day advance purchase round-trip adult fares when booked in conjunction with whale watching or an overnight package. 1 child per paying adult, additional children at an extra cost.

Advisory: Due to the time spent on the boat during this nearly 12 hour San Juan Island day trip with Whale Watching, it is not recommended for children under 6. Adults traveling with young children should plan accordingly by bringing books, videos, games, toys etc. to assist in keeping them occupied. There is a great deal to see throughout the day but it may be more than a young child can appreciate.

Prices are in US Dollars and include tax. 1-day advance purchase, date and voyage restrictions may apply. Child fare not available for youth groups. Changes or cancellations received 2 or more days before tour start date are fully refundable. 1 day prior to tour start date, the reservation is non-refundable.

A $2.40 pp/RT Port fee and $2 pp/RT security fee will be added to all Friday Harbor fares, until further notice.

NOTE: Ferry Service between Seattle/Victoria, BC and Seattle/San Juan Island are passenger service only. No vehicles.

Fares subject to WUTC approval but may include a whale watching component not subject to UTC.

Subject to change.

Only dates with additional departures are shown * Additional sailing

Departures From Seattle

Departures From Victoria

September 19 Mon

7:30 AM 8:30 AM*. 3:15 PM

September 19 Mon

11:30 AM, 12:30 PM* 7:00 PM

September 20 Tue

7:30 AM 8:30 AM*. 3:15 PM

September 20 Tue

11:30 AM, 12:30 PM* 7:00 PM

September 22 Thu

7:30 AM 12:45 PM*. 3:15 PM

September 22 Thu

11:30 AM, 4:30 PM* 7:00 PM

Clipper Ferry

Schedules and Fares

cargo

Our Fleet

Travel Information

Specials

Things to do

About Us

Groups

Agents

Please Call for Mobile Booking

From your mobile device please call to book your trip between the hours of 6:30 am and 9 pm, daily, PST. To book online you can use your desktop/tablet computer anytime.

Buy Uro-Cephoral - Cefixime - Online Without Prescriptions, Uro-Cephoral

Cefixime (Uro-cephoral)

Cefixime is used for treating infections caused by certain bacteria. Cefixime is a cephalosporin antibiotic. It works by killing sensitive bacteria.

Use Cefixime as directed by your doctor.

Take Cefixime by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, continue using Cefixime for the full course of treatment even if you feel better in a few days.

If you miss a dose of Cefixime, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cefixime.

Store Cefixime at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cefixime out of the reach of children and away from pets.

Do NOT use Cefixime if:

you are allergic to any ingredient in Cefixime or to other cephalosporins (eg, cephalexin)

you will be having a live typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Cefixime. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin (eg, amoxicillin) or beta-lactam antibiotic (eg, imipenem)

if you have diarrhea, stomach or bowel problems (eg, inflammation), bleeding or blood clotting problems, liver problems, or poor nutrition

if you have a history of kidney problems or you are on dialysis treatment.

Some medicines may interact with Cefixime. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Anticoagulants (eg, warfarin) or carbamazepine because the risk of their side effects may be increased by Cefixime

Live typhoid vaccines because their effectiveness may be decreased by Cefixime.

Ask your health care provider if Cefixime may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Cefixime may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Cefixime with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Do not change dose forms (eg, tablets, suspension) of Cefixime without talking with your doctor.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Cefixime only works against bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Cefixime for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of Cefixime may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Cefixime may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

Do not receive a live typhoid vaccine while you are taking Cefixime. It may not work as well. Talk with your doctor if you are scheduled to receive a live typhoid vaccine.

Diabetes patients - Cefixime may cause the results of some tests for urine glucose or urine ketones to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

Cefixime may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Cefixime.

Cefixime should be used with extreme caution in children younger 6 months; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cefixime while you are pregnant. It is not known if Cefixime is found in breast milk. If you are or will be breast-feeding while you use Cefixime, check with your doctor or pharmacist. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; gas; loose stools; nausea; stomach pain or upset.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; decreased urination; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe nausea or vomiting; severe stomach pain or cramping; unusual bruising or bleeding; vaginal discharge or itching; white spots in the mouth; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Ibumed, Ibumed

Ibumed

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Was this page helpful?

Valpress - Manufacturer Cornuda, Valpress

VALPRESS

accessori per coperture, tetti ventilati, ganci fermacoppi, guaina traspirante, colmo ventilato, barriere antivolatile, griglie di ventilazione, arcoppo, accessori per casseforme, distanziatori, attrezzatura edile, tetti fotovoltaici, generatori eolici, inverter, accumulatori, sistemi di montaggio e cablaggio, regolatori di carica, moduli fotovoltaici, monocristallino, policristallino, amorfo

accessori per coperture, tetti ventilati, ganci fermacoppi, guaina traspirante, colmo ventilato, barriere antivolatile, griglie di ventilazione, arcoppo, accessori per casseforme, distanziatori, attrezzatura edile, tetti fotovoltaici, generatori eolici, inverter, accumulatori, sistemi di montaggio e cablaggio, regolatori di carica, moduli fotovoltaici, monocristallino, policristallino, amorfo

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