Aramycin, A Streptothricin-Like Antibiotic, Produced By A Local Strain Of Streptomyces Mys-20a, Amer


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Zentralbl Bakteriol Naturwiss. 1978;133(4):369-74.

Abstract

One strain of actinomycetes, designated as MYS-20 A, was isolated from the Egyptian soil. The organism produces a substance that appears to be different from previously described antibiotics. The substance was named "Aramycin". A description of the strain of actinomyces MYS 20 A is given as well as conditions of growth for maximum production of the antibiotic substance. The bacterial and fungal spectra of aramycin are given. The substance appears to exhibit a very significant cytotoxic effect. The antibiotic was toxic to mice, the lethal dose being, however, about 15 times higher than the curative dose.

PMID

726709 [PubMed - indexed for MEDLINE]